Limin Liu, PhD

Limin Liu, PhD

Assistant Professor, Department of Microbiology and Immunology, UCSF

Phone: (415) 476-1466 (voice)
Box 0414, UCSF
San Francisco, CA 94143-0414

Cancer Center Membership

Associate Member ยป Non-aligned


University of Science & Technology of China, Hefei, China, B.S., 1986, Biology
University of Missouri, Columbia, MO, Ph.D., 1995, Molecular Biology
Duke University Medical Center, Nitric oxide biology

Professional Experience

  • 1996- 1997
    Research Associate, Department of Animal Sciences, University of Missouri-Columbia
  • 1997- 2004
    Research Associate, Department of Medicine, Division of Pulmonary Medicine, Duke University Medical Center
  • 1998-2003
    Research Associate, Howard Hughes Medical Institute, Duke University Medical Center

Honors & Awards

  • 1989-1990
    Scholarship, Division of Biological Sciences, University of Missouri
  • 1989-1993
    Predoctoral Fellowship, Molecular Biology Program, University of Missouri
  • 1994
    New Investigator Award (First Place), Society for the Study of Reproduction (Biology of Reproduction, Vol. 52, pp. 261)

Selected Publications

  • Wu WY, Zhao YG and Liu L (1989). Trophic effect of slow nerve on minced fast muscle from newly hatched chicks transplanted into three-week chicks. Chin J Physiol Sci 5:95-97.
  • Wu WY, Zhao YG, Liu L, Lu DX and Tian, WH (1990). The second stage commitment of chick muscle satellite cells and its relation to the state of innervation. Chin J Physiol Sci 6:19-29.
  • Liu L, Leaman DW, Bixby JA and Roberts RM (1996). A type 1 ovine interferon with limited similarity to IFN-alpha, IFN-omega, and IFN-tau: gene structure, biological properties and unusual species specificity. Biochem Biophys Acta 1294:55-62.
  • Liu L and Roberts RM (1996). Silencing of the gene for the beta-subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/4. J Biol Chem 271:16683-16689.
  • Liu L, Leaman DW and Roberts RM (1996). The interferon-tau genes of the giraffe, a nonbovid species. J Interferon Cytokine Res 16:949-951.
  • Roberts RM, Liu L and Alexenko A (1997). New and atypical families of type I interferons in mammals: comparative functions, structures and evolutionary relationships. Prog Nucleic Acid Res Mol Biol 56:287-325.
  • Liu L, Leaman DW, Villalta M and Roberts RM (1997). Silencing of the gene for the alpha-subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/4. Mol Endocrinol 11:1651-1658.
  • Roberts RM, Liu L, Guo Q, Leaman D and Bixby J (1998) The evolution of type I interferons. J Interferon Cytokine Res 18:805-816.
  • Liu L, Leaman DW and Roberts RM (1998). Possible role of the transcription factor Oct-3/4 in control of human chorionic gonadotropin expression. In: D. Carson, ed., Embryo Implantation: Molecular, Cellular and Clinical Aspects (Serono Symposium), pp.261-270.
  • Mannick JB, Hausladen A, Liu L, Hess DT, Zeng M, Miao QX, Kane LS, Gow AJ, Stamler JS (1999). Fas-induced caspase denitrosylation. Science 284:651-654.
  • Liu L, Stamler JS. (1999) NO: an inhibitor of cell death. Cell Death Differ 6:937-942
  • Liu L, Zeng M, Stamler JS. (1999) Hemoglobin induction in mouse macrophages. Proc Natl Acad Sci USA 96:6643-6647.
  • Eu JP, Liu L, Zeng M and Stamler JS (2000). An apoptotic model for nitrosative stress. Biochemistry 39:1040-1047.
  • Liu L, Zeng M, Hausladen A, Heitman J, Stamler JS (2000). Protection from nitrosative stress by yeast flavohemoglobin. Proc Natl Acad Sci USA 97:4672-4676.
  • Ealy AD*, Larson SF*, Liu L*, Winkelman GL, Kubisch HM, Alexnko AP, Bixby JA, Roberts RM. (2001) Polymorphic forms of expressed bovine interferon-tau genes: relative transcript abundance during early placental development, promoter sequences of genes and biological activity of protein products. Endocrinology 142:2906-2915. *These authors contributed equally.
  • Liu L, Hausladen A, Zeng M, Loretta Que, Heitman J, Stamler JS (2001). A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. Nature 410:490-494.
  • Matsumoto A, Comatas KE, Liu L, Stamler JS (2003). Screening for nitric oxide-dependent protein-protein interactions. Science 301:657-661.
  • Jesus-Berrios MD, Liu L, Nussbaum JC, Cox GM, Stamler JS, Heitman J (2003). Enzymes that counteract nitrosative stress promote fungal virulence. Current Biology 13:1963-1968.
  • Liu L, Yan Y, Zeng M, Zhang J, Hanes MA, Ahearn G, McMahon TJ, Dickfeld T, Marshall HE, Que LG, Stamler JS (2004). Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell 116:617-628.