Assistant Professor, Brain Tumor Research Center and Department of Neurological Surgery; and Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF
Education
University of Vienna BioCenter, Vienna, MS, BA, 1985 -1991, Cell and Molecular Biology and Biochemistry
University of Vienna BioCenter, Vienna, PhD, 1991-1996, Cell & Molecular Biology
Institute of Molecular Pathology, Vienna, Postdoc, 1996-1997
University of California, San Francisco, Dept of Physiology, Postdoc, 1997-2002
Professional Experience
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2002-2003
Postgraduate Researcher, Department of Physiology, University of California, San Francisco
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2003-2005
Investigator, GeneCenter and Institute of Biochemistry at the University of Munich
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2005-2008
Associate Research Biochemist, Department of Neurological Surgery, University of California, San Francisco
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2008-present
Assistant Professor, Brain Tumor Research Center and Department of Neurological Surgery, University of California, San Francisco
Honors & Awards
- 1990
Diploma Fellowship, Institute of Molecular Pathology - 1991-96
PhD Fellowship, Institute for Molecular Pathology - 1993
European Molecular Biology Organisation short-term fellowship - 1994
Federation of European Biochemical Societies short-term fellowship - 1996
European Molecular Biology Organisation long-term fellowship - 1999
Human Frontiers Science Program Organization long-term fellowship - 2003
PO 1 Research Grant; German Research Council (DFG) # SFB 413 - 2004
PO 1 Research Grant; German Research Council (DFG) # SFB 413 - 2004-06
Award for Outstanding Women in Life Sciences (University of Munich) - 2005-06
Bavarian California Technology Award - 2006
California Breast Cancer Research Program/CBRCP, IDEA Award, San Francisco, USA - 2007-2008
National Brain Tumor Foundation, Oligodendroglioma Award, San Francisco, USA - 2007-2008
Brain Tumor SPORE, Career Development Research Award, San Francisco, USA - 2010
American Brain Tumor Association, Discovery Award, Des Plaines, USA
Selected Publications
- Wade A, Robinson AE, Engler JR, Petritsch C, James CD, Phillips JJ. Proteoglycans and their roles in brain cancer. FEBS J. 2013 May; 280(10):2399-417.
View on PubMed - Huillard E, Hashizume R, Phillips JJ, Griveau A, Ihrie RA, Aoki Y, Nicolaides T, Perry A, Waldman T, McMahon M, Weiss WA, Petritsch C, James CD, Rowitch DH. Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8710-5.
View on PubMed - Sugiarto S, Persson AI, Munoz EG, Waldhuber M, Lamagna C, Andor N, Hanecker P, Ayers-Ringler J, Phillips J, Siu J, Lim DA, Vandenberg S, Stallcup W, Berger MS, Bergers G, Weiss WA, Petritsch C. Asymmetry-defective oligodendrocyte progenitors are glioma precursors. Cancer Cell. 2011 Sep 13; 20(3):328-40.
View on PubMed - Ouyang Y, Petritsch C, Wen H, Jan L, Jan YN, Lu B. Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development. 2011 Jun; 138(11):2185-96.
View on PubMed - Persson AI, Petritsch C, Swartling FJ, Itsara M, Sim FJ, Auvergne R, Goldenberg DD, Vandenberg SR, Nguyen KN, Yakovenko S, Ayers-Ringler J, Nishiyama A, Stallcup WB, Berger MS, Bergers G, McKnight TR, Goldman SA, Weiss WA. Non-stem cell origin for oligodendroglioma. Cancer Cell. 2010 Dec 14; 18(6):669-82.
View on PubMed - Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med. 2008; 6:14.
View on PubMed - Erben V, Waldhuber M, Langer D, Fetka I, Jansen RP, Petritsch C. Asymmetric localization of the adaptor protein Miranda in neuroblasts is achieved by diffusion and sequential interaction of Myosin II and VI. J Cell Sci. 2008 May 1; 121(Pt 9):1403-14.
View on PubMed - Du R, Petritsch C, Lu K, Liu P, Haller A, Ganss R, Song H, Vandenberg S, Bergers G. Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM. Neuro Oncol. 2008 Jun; 10(3):254-64.
View on PubMed - Du R, Lu KV, Petritsch C, Liu P, Ganss R, Passegué E, Song H, Vandenberg S, Johnson RS, Werb Z, Bergers G. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell. 2008 Mar; 13(3):206-20.
View on PubMed - Waldhuber M, Emoto K, Petritsch C. The Drosophila caspase DRONC is required for metamorphosis and cell death in response to irradiation and developmental signals. Mech Dev. 2005 Jul; 122(7-8):914-27.
View on PubMed - Ye B, Petritsch C, Clark IE, Gavis ER, Jan LY, Jan YN. Nanos and Pumilio are essential for dendrite morphogenesis in Drosophila peripheral neurons. Curr Biol. 2004 Feb 17; 14(4):314-21.
View on PubMed - Petritsch C, Tavosanis G, Turck CW, Jan LY, Jan YN. The Drosophila myosin VI Jaguar is required for basal protein targeting and correct spindle orientation in mitotic neuroblasts. Dev Cell. 2003 Feb; 4(2):273-81.
View on PubMed - Petritsch C, Beug H, Balmain A, Oft M. TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest. Genes Dev. 2000 Dec 15; 14(24):3093-101.
View on PubMed - Edelmann HM, Kühne C, Petritsch C, Ballou LM. Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts. J Biol Chem. 1996 Jan 12; 271(2):963-71.
View on PubMed - Petritsch C, Woscholski R, Edelmann HM, Ballou LM. Activation of p70 S6 kinase and erk-encoded mitogen-activated protein kinases is resistant to high cyclic nucleotide levels in Swiss 3T3 fibroblasts. J Biol Chem. 1995 Nov 3; 270(44):26619-25.
View on PubMed - Petritsch C, Woscholski R, Edelmann HM, Parker PJ, Ballou LM. Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors. Eur J Biochem. 1995 Jun 1; 230(2):431-8.
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