Professor Emeritus, Department of Laboratory Medicine, UCSF; Associate Director, Shared Resources, UCSF Helen Diller Family Comprehensive Cancer Center
Education
University of Michigan, Ann Arbor, MI, B.A., 1966, Physics
University of California, San Diego, CA, Ph.D., 1974, Physics
University of California, Los Angeles, Postdoc, 1975, Medical Physics
Professional Experience
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1966-1974
NSF Graduate Fellow and Research Assistant, University of California, San Diego, California. Assistant Research Physicist, University of California, San Diego, California.
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1975-1977
NIH Postdoctoral Fellow, University of California, Los Angeles, California.
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1977-1991
Biophysicist, Lawrence Livermore Laboratory, University of California, Livermore, California
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1991-1992
Associate Professor, Laboratory Medicine, University of California - San Francisco, San Francisco, California.
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1992-present
Scientist, Lawrence Berkeley National Laboratory (joint appointment)
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1993-2009
Professor, Laboratory Medicine, University of California San Francisco, San Francisco, California
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2010-present
Professor Emeritus, Laboratory Medicine, University of California San Francisco, San Francisco, California
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2006-present
Associate Director Shared Resources, UCSF Helen Diller Family Comprehensive Cancer Center
Honors & Awards
- Phi Beta Kappa, Sigma XI, Phi Kappa Phi
- 2001
Curt Stern Award, American Society of Human Genetics - 2008
Team Science Award, American Association for Cancer Research
Selected Publications
- Magbanua MJ, Sosa EV, Roy R, Eisenbud LE, Scott JH, Olshen A, Pinkel D, Rugo HS, Park JW. Genomic profiling of isolated circulating tumor cells from metastatic breast cancer patients. Cancer Res. 2013 Jan 1; 73(1):30-40.
View on PubMed - Magbanua MJ, Sosa EV, Scott JH, Simko J, Collins C, Pinkel D, Ryan CJ, Park JW. Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer. BMC Cancer. 2012; 12:78.
View on PubMed - Bhattacharya A, Roy R, Snijders AM, Hamilton G, Paquette J, Tokuyasu T, Bengtsson H, Jordan RC, Olshen AB, Pinkel D, Schmidt BL, Albertson DG. Two distinct routes to oral cancer differing in genome instability and risk for cervical node metastasis. Clin Cancer Res. 2011 Nov 15; 17(22):7024-34.
View on PubMed - Clark SM, Hamilton GE, Nordmeyer RA, Uber D, Cornell EW, Brown N, Segraves R, Davis R, Albertson DG, Pinkel D. High-efficiency microarray printer using fused-silica capillary tube printing pins. Anal Chem. 2008 Oct 1; 80(19):7639-42.
View on PubMed - Viros A, Fridlyand J, Bauer J, Lasithiotakis K, Garbe C, Pinkel D, Bastian BC. Improving melanoma classification by integrating genetic and morphologic features. PLoS Med. 2008 Jun 3; 5(6):e120.
View on PubMed - North JP, Kageshita T, Pinkel D, LeBoit PE, Bastian BC. Distribution and significance of occult intraepidermal tumor cells surrounding primary melanoma. J Invest Dermatol. 2008 Aug; 128(8):2024-30.
View on PubMed - Herlyn M, Halaban R, Ronai Z, Schuchter L, Berwick M, Pinkel D. Roadmap for new opportunities in melanoma research. Semin Oncol. 2007 Dec; 34(6):566-76.
View on PubMed - Pinkel D. Analytical description of mutational effects in competing asexual populations. Genetics. 2007 Dec; 177(4):2135-49.
View on PubMed - Curtin JA, Pinkel D, Bastian BC. Absence of PDGFRA mutations in primary melanoma. J Invest Dermatol. 2008 Feb; 128(2):488-9.
View on PubMed - Bastian BC, Pinkel D. Expanding the genetic spectrum of pigmentation. Pigment Cell Melanoma Res. 2008 Oct; 21(5):507-8.
View on PubMed - Tokuyasu TA, Cotter PD, Segraves R, Harris J, Elder ME, Gonzales M, Pinkel D, Albertson DG, Rauen KA. Detection of single clone deletions using array CGH: identification of submicroscopic deletions in the 22q11.2 deletion syndrome as a model system. Am J Med Genet A. 2007 May 1; 143A(9):925-32.
View on PubMed - Climent J, Dimitrow P, Fridlyand J, Palacios J, Siebert R, Albertson DG, Gray JW, Pinkel D, Lluch A, Martinez-Climent JA. Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer. Cancer Res. 2007 Jan 15; 67(2):818-26.
View on PubMed - Gajduskova P, Snijders AM, Kwek S, Roydasgupta R, Fridlyand J, Tokuyasu T, Pinkel D, Albertson DG. Genome position and gene amplification. Genome Biol. 2007; 8(6):R120.
View on PubMed - Thorns C, Bastian B, Pinkel D, Roydasgupta R, Fridlyand J, Merz H, Krokowski M, Bernd HW, Feller AC. Chromosomal aberrations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma unspecified: A matrix-based CGH approach. Genes Chromosomes Cancer. 2007 Jan; 46(1):37-44.
View on PubMed - Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, Kuo WL, Lapuk A, Neve RM, Qian Z, Ryder T, Chen F, Feiler H, Tokuyasu T, Kingsley C, Dairkee S, Meng Z, Chew K, Pinkel D, Jain A, Ljung BM, Esserman L, Albertson DG, Waldman FM, Gray JW. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell. 2006 Dec; 10(6):529-41.
View on PubMed - Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, Clark L, Bayani N, Coppe JP, Tong F, Speed T, Spellman PT, DeVries S, Lapuk A, Wang NJ, Kuo WL, Stilwell JL, Pinkel D, Albertson DG, Waldman FM, McCormick F, Dickson RB, Johnson MD, Lippman M, Ethier S, Gazdar A, Gray JW. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell. 2006 Dec; 10(6):515-27.
View on PubMed - Stransky N, Vallot C, Reyal F, Bernard-Pierrot I, de Medina SG, Segraves R, de Rycke Y, Elvin P, Cassidy A, Spraggon C, Graham A, Southgate J, Asselain B, Allory Y, Abbou CC, Albertson DG, Thiery JP, Chopin DK, Pinkel D, Radvanyi F. Regional copy number-independent deregulation of transcription in cancer. Nat Genet. 2006 Dec; 38(12):1386-96.
View on PubMed - Mestre-Escorihuela C, Rubio-Moscardo F, Richter JA, Siebert R, Climent J, Fresquet V, Beltran E, Agirre X, Marugan I, Marín M, Rosenwald A, Sugimoto KJ, Wheat LM, Karran EL, García JF, Sanchez L, Prosper F, Staudt LM, Pinkel D, Dyer MJ, Martinez-Climent JA. Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas. Blood. 2007 Jan 1; 109(1):271-80.
View on PubMed - Curtin JA, Busam K, Pinkel D, Bastian BC. Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol. 2006 Sep 10; 24(26):4340-6.
View on PubMed - Sharp AJ, Hansen S, Selzer RR, Cheng Z, Regan R, Hurst JA, Stewart H, Price SM, Blair E, Hennekam RC, Fitzpatrick CA, Segraves R, Richmond TA, Guiver C, Albertson DG, Pinkel D, Eis PS, Schwartz S, Knight SJ, Eichler EE. Discovery of previously unidentified genomic disorders from the duplication architecture of the human genome. Nat Genet. 2006 Sep; 38(9):1038-42.
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