Research Summary

I work 2-1/2 days a week in the Radiation Oncology clinic at the Parnassus campus, specializing in the treatment of various kinds of brain tumors and brain metastases using various treatment modalities with particular expertise in Gamma Knife radiosurgery, and in palliative radiotherapy.

Research Funding

  • September 1, 1986 - August 31, 1989 - INTERSTITIAL MICROWAVE, RF &FERROMAGNETIC HYPERTHERMIA , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K08CA001169

Education

University of Missouri, Columbia, Missouri, B.S., 1976, Electrical Engineering
Stanford University Medical School, M.D., 1981, Medicine

Honors & Awards

  • 1975
    Eta Kappa Nu
  • 1975
    Pi Mu Epsilon
  • 1975
    Mortar Board
  • 1976
    Tau Beta Pi
  • 1976
    Phi Kappa Phi
  • 1976
    B.S. degree summa cum laude
  • 1979
    American Cancer Society Medical Student Summer Fellowship in Radiation Therapy at Stanford University School of Medicine
  • 1984-86
    American Cancer Society Regular Clinical Fellowship in Radiation Oncology at the University of California, San Francisco
  • 1985
    American Society for Therapeutic Radiology and Oncology Resident Essay Award
  • 1986
    NIH Clinical Investigator Award
  • 2002
    Fellowship in the American College of Radiology (FACR)

Selected Publications

  • Sneed PK, Gutin PH, Stauffer PR, Phillips TL, Prados MD, Weaver KA, et al: Thermoradiotherapy of recurrent malignant brain tumors. Int J Radiat Oncol Biol Phys 23(4):853-861, 1992.
  • Scharfen CO, Sneed PK, Wara WM, Larson DA, Phillips TL, Prados MD, et al: High activity iodine-125 interstitial implant for gliomas. Int J Radiat Oncol Biol Phys 24(4):583-591, 1992.
  • Sause WT, Scott C, Kirsch R, Rotman M, Sneed PK, Janjan N, et al: Phase I/II trial of accelerated fractionation in brain metastases RTOG 85-28. Int J Radiat Oncol Biol Phys 26(4):653-657, 1993.
  • Sneed PK, Gutin PG, Larson DA, Malec MK, Phillips TL, Prados MD, et al: Patterns of recurrence of glioblastoma multiforme after external irradiation followed by implant boost. Int J Radiat Oncol Biol Phys 29:719-727, 1994.
  • Sneed PK, Prados MD, McDermott MW, Larson DA, Malec MK, Lamborn KR, et al: Large effect of age on survival of patients with glioblastoma treated with radiotherapy and implant boost. Neurosurgery 36(5):898-904, 1995.
  • Sneed PK, Albright NW, Wara WM, Prados MD, Wilson CB: Fetal dose estimates for radiotherapy of brain tumors during pregnancy. Int J Radiat Oncol Biol Phys 32(3):823-830, 1995.
  • Sneed PK, Lamborn KR, Larson DA, Prados MD, Malec MK, McDermott MW, et al: Demonstration of brachytherapy boost dose-response relationships in glioblastoma multiforme. Int J Radiat Oncol Biol Phys 35(1):37-44, 1996.
  • Sneed PK, Russo C, Scharfen CO, Prados MD, Malec MK, Larson DA, et al: Long-term follow-up after high-activity iodine-125 brachytherapy for pediatric brain tumors. Pediatric Neurosurg 24:314-322, 1996.
  • Bauman GS, Sneed PK, Wara WM, Stalpers LJA, Chang SM, McDermott MW, et al: Reirradiation of primary CNS tumors. Int J Radiat Oncol Biol Phys 36(2):433-441, 1996.
  • Shu HKG, Sneed PK, Shiau CY, McDermott MW, Park E, Ho M, et al. Factors influencing survival after gamma knife radiosurgery for patients with single and multiple brain metastases. The Cancer J Sci Amer 2:335-342, 1996.
  • Shiau CY, Sneed PK, Shu HKG, Nowak P, McDermott MW, et al: Radiosurgery for brain metastases: relationship of radiosurgery dose and pattern of enhancement to local control. Int J Radiat Oncol Biol Phys 37(2):375-383, 1997.
  • Sneed PK, Stauffer PR, McDermott MW, Diederich CJ, Lamborn KR, Prados MD, et al: Survival benefit of hyperthermia in a prospective randomized trial of brachytherapy boost +/- hyperthermia for glioblastoma multiforme. Int J Radiat Oncol Biol Phys 40(2):287-295, 1998.
  • Seung SK, Sneed PK, McDermott MW, Shu H-KG, Leong SP, Chang S, et al: Gamma Knife radiosurgery for malignant melanoma brain metastases. The Cancer J Sci Amer 4(2):103-109, 1998.
  • Sneed PK, Lamborn KR, Forstner JM, McDermott MW, Chang S, Park E, et al: Radiosurgery for brain metastases: is whole brain radiotherapy necessary? Int J Radiat Oncol Biol Phys 43(3):549-558, 1999.
  • Ojemann SG, Sneed PK, Larson DA, Gutin PH, Berger MS, Verhey L, et al: Radiosurgery for malignant meningioma: results in 22 patients. J Neurosurg 93(Suppl 3):62-67, 2000.
  • Goodman KA, Sneed PK, McDermott MW, Shiau C-Y, Lamborn KR, Chang S, et al: Relationship between pattern of enhancement and local control of brain metastases after radiosurgery. Int J Radiat Oncol Biol Phys 50(1):139-146, 2001.
  • Hoffman R, Sneed PK, McDermott MW, Chang S, Lamborn KR, Park E, et al: Radiosurgery for brain metastases from primary lung carcinoma. Cancer J Sci Amer 7(2):121-131, 2001.
  • Pirzkall A, McKnight T, Graves EE, Carol MP, Sneed PK, Wara WW, et al: MR-spectroscopy guided target delineation for high-grade gliomas. Int J Radiat Oncol Biol Phys 50(4):915-928, 2001.
  • Barker FG 2nd, Simmons ML, Chang SM, Prados MD, Larson DA, Sneed PK, et al: EGFR overexpression and radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys 51(2):410-418, 2001.
  • Sanghavi SN, Miranpuri SS, Chappell R, Buatti JM, Sneed PK, Suh JH, et al: Radiosurgery for patients with brain metastases: a multi-institutional analysis, stratified by the RTOG recursive partitioning analysis method. Int J Radiat Oncol Biol Phys 51(2):426-434, 2001.
  • Nakamura JL, Verhey LJ, Smith V, Petti PL, Lamborn KR, Larson DA, Wara WM, McDermott MW, Sneed PK: Dose conformity of Gamma Knife radiosurgery and risk factors for complications. Int J Radiat Oncol Biol Phys 51(5):1313-1319, 2001.
  • Barker FG 2nd, Chang SM, Larson DA, Sneed PK, Wara WM, Wilson CB, Prados MD: Age and radiation response in glioblastoma multiforme. Neurosurgery 49(6):1288-1298, 2001.
  • Sneed PK, Suh JH, Goetsch SJ, Sanghavi SN, Chappell R, Buatti JM, et al: A multi-institutional review of radiosurgery alone vs. radiosurgery with whole brain radiotherapy as the initial management of brain metastases. Int J Radiat Oncol Biol Phys 53(3):519-526, 2002.
  • Pirzkall A, Nelson SJ, McKnight TR, Takahashi MM, Li X, Graves EE, Verhey LJ, Wara WW, Larson DA, Sneed PK: Metabolic imaging of low-grade gliomas with three-dimensional magnetic resonance spectroscopy. Int J Radiat Oncol Biol Phys 53(5):1254-1264, 2002.
  • Nakamura JL, Pirzkall A, Carol MP, Xia P, Smith V, Wara WM, Petti PL, Verhey LJ, Sneed PK: Comparison of intensity-modulated radiosurgery with gamma knife radiosurgery for challenging skull base lesions. Int J Radiat Oncol Biol Phys 55(1):99-109, 2003.

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