University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Tarik Tihan, MD, PhD

Tarik Tihan, MD, PhD

Associate Professor, Department of Pathology, UCSF

Cancer Center Program Memberships

Neurologic Oncology

Education

University of Istanbul, School of Medicine, MD, 1979-85, Medicine
University of Istanbul/Univ. Of Vienna, PhD, 1986-89, Biochemistry


Professional Experience

  • 1985-1986
    Kahramanmaras State Hospital, Department of Critical Care, Turkey. House Officer.
  • 1986-1989
    University of Istanbul, Istanbul Medical School, Department of Clinical Biochemistry. Clinical Instructor and Research Assistant.
  • 1988-1989
    University of Vienna, Department of Medical Chemistry, Austria. Research Assistant. Research Grant from the Austrian government, Ministry of Education, (Bundesministerium fuer Auswaertige Angelegenheiten).
  • 1989
    Doctorate, University of Istanbul, Department of Clinical Biochemistry. Diplomate of the Ministry of Health and Social Aid for the medical doctorate in Clinical Biochemistry.
  • 1989-1990
    University of South Florida, Department of Internal Medicine & H. Lee Moffitt Cancer Center. Research Associate.
  • 1991-1992
    Beth Israel Medical Center, Department of Neurosurgery. Manager of the Recanati Research Laboratory.
  • 1992-1994
    Beth Israel Medical Center, Department of Pathology, Resident
  • 1994-1995
    Memorial Sloan-Kettering Cancer Center, Department of Pathology. Fellow in Oncologic Pathology.
  • 1996
    American Board of Pathology Certificate of Anatomic Pathology.
  • 1995-1997
    State University of New York at Stony Brook, Department of Pathology. Fellow in Neuropathology.
  • 1997-2000
    Johns Hopkins Medical Institutions, Department of Pathology, Clinical Instructor. Johns Hopkins Bayview Medical Center, Department of Pathology. Attending Pathologist in Anatomic Pathology and Cytopathology.
  • 2000-2002
    Johns Hopkins Medical Institutions, Department of Pathology, Assistant Professor
  • 2002-present
    UCSF School of Medicine, Department of Pathology, Neuropathology Unit, Associate Professor
  • 2002-present
    Principal Investigator, Brain Tumor Research Center, Department of Neurological Surgery

Honors & Awards

  • 2001-2003
    John Hopkins W. Barry Wood Jr, Award in excellence in teaching
  • 2003
    USCF Department of Pathology Teaching Excellence Award
  • 2003, 2005
    UCSF Department of Neurological Surgery Teaching Excellence in Basic Science Award

Selected Publications

  1. Mandel-Brehm C, Retallack H, Knudsen GM, Yamana A, Hajj-Ali RA, Calabrese LH, Tihan T, Sample HA, Zorn KC, Gorman MP, Madan Cohen J, Sreih AG, Marcus JF, Josephson SA, Douglas VC, Gelfand JM, Wilson MR, DeRisi JL. Exploratory proteomic analysis implicates the alternative complement cascade in primary CNS vasculitis. Neurology. 2019 Jul 03.
    View on PubMed
  2. Çakir E, Oran G, Yüksek GE, Ding C, Tihan T. Intraoperative Consultations of Central Nervous System Tumors: A Review for Practicing Pathologists and Testing of an Algorithmic Approach. Turk Patoloji Derg. 2019 May 20.
    View on PubMed
  3. Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, Kline CN, Gupta N, Raffel C, Samuel D, Ruiz-Diaz I, Magaki S, Wilson D, Neltner J, Al-Hajri Z, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Schniederjan M, Cha S, Perry A, Solomon DA. High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis. Brain Pathol. 2019 May 18.
    View on PubMed
  4. Yousef A, Rutkowski MJ, Yalcin CE, Eren OC, Caliskan I, Tihan T. Sporadic and Von-Hippel Lindau disease-associated spinal hemangioblastomas: institutional experience on their similarities and differences. J Neurooncol. 2019 Jul; 143(3):547-552.
    View on PubMed
  5. Kulac I, Tihan T. Pilomyxoid astrocytomas: a short review. Brain Tumor Pathol. 2019 Apr; 36(2):52-55.
    View on PubMed
  6. Lee JC, Mazor T, Lao R, Wan E, Diallo AB, Hill NS, Thangaraj N, Wendelsdorf K, Samuel D, Kline CN, Banerjee A, Auguste K, Raffel C, Gupta N, Berger M, Raleigh DR, Shai A, Phillips JJ, Bollen AW, Tihan T, Perry A, Costello J, Solomon DA. Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma. Acta Neuropathol. 2019 May; 137(5):851-854.
    View on PubMed
  7. Lee JC, Sharifai N, Dahiya S, Kleinschmidt-DeMasters BK, Rosenblum MK, Reis GF, Samuel D, Siongco AM, Santi M, Storm PB, Ferris SP, Bollen AW, Pekmezci M, Solomon DA, Tihan T, Perry A. Clinicopathologic features of anaplastic myxopapillary ependymomas. Brain Pathol. 2019 01; 29(1):75-84.
    View on PubMed
  8. Winkler EA, Birk H, Burkhardt JK, Chen X, Yue JK, Guo D, Rutledge WC, Lasker GF, Partow C, Tihan T, Chang EF, Su H, Kim H, Walcott BP, Lawton MT. Reductions in brain pericytes are associated with arteriovenous malformation vascular instability. J Neurosurg. 2018 Dec 01; 129(6):1464-1474.
    View on PubMed
  9. Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Bastian BC, Grenert JP, Kline CN, Mueller S, Banerjee A, Nicolaides T, Gupta N, Berger MS, Lee HS, Pekmezci M, Tihan T, Bollen AW, Perry A, Shieh JTC, Solomon DA. The genetic landscape of anaplastic pleomorphic xanthoastrocytoma. Brain Pathol. 2019 01; 29(1):85-96.
    View on PubMed
  10. Safaee MM, Jonzzon S, López GY, Asaikar S, Tihan T, Glenn OA, Gupta N. Perilesional edema associated with an intracranial calcifying pseudoneoplasm of the neuraxis in a child: case report and review of imaging features. J Neurosurg Pediatr. 2018 Nov 01; 22(5):528-531.
    View on PubMed
  11. Payabvash S, Tihan T, Cha S. Volumetric voxelwise apparent diffusion coefficient histogram analysis for differentiation of the fourth ventricular tumors. Neuroradiol J. 2018 Dec; 31(6):554-564.
    View on PubMed
  12. López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C, Gupta N, Kunwar S, Mummaneni P, Aghi M, Theodosopoulos P, Berger M, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. The genetic landscape of gliomas arising after therapeutic radiation. Acta Neuropathol. 2019 Jan; 137(1):139-150.
    View on PubMed
  13. Payabvash S, Tihan T, Cha S. Differentiation of Cerebellar Hemisphere Tumors: Combining Apparent Diffusion Coefficient Histogram Analysis and Structural MRI Features. J Neuroimaging. 2018 Nov; 28(6):656-665.
    View on PubMed
  14. Ding C, Tihan T. Recent Progress in the Pathology and Genetics of Pilocytic and Pilomyxoid Astrocytomas Balkan Med J. 2019 01 01; 36(1):3-11.
    View on PubMed
  15. Pekmezci M, Villanueva-Meyer JE, Goode B, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Chamyan G, Maher OM, Khatib Z, Kleinschmidt-DeMasters BK, Samuel D, Mueller S, Banerjee A, Clarke JL, Cooney T, Torkildson J, Gupta N, Theodosopoulos P, Chang EF, Berger M, Bollen AW, Perry A, Tihan T, Solomon DA. The genetic landscape of ganglioglioma. Acta Neuropathol Commun. 2018 06 07; 6(1):47.
    View on PubMed
  16. Winkler EA, Rutledge C, Ward M, Tihan T, Sneed PK, Barbaro N, Garcia P, McDermott M, Chang EF. Radiation-induced Cavernous Malformation as a Late Sequelae of Stereotactic Radiosurgery for Epilepsy. Cureus. 2018 Mar 11; 10(3):e2308.
    View on PubMed
  17. Goode B, Mondal G, Hyun M, Ruiz DG, Lin YH, Van Ziffle J, Joseph NM, Onodera C, Talevich E, Grenert JP, Hewedi IH, Snuderl M, Brat DJ, Kleinschmidt-DeMasters BK, Rodriguez FJ, Louis DN, Yong WH, Lopes MB, Rosenblum MK, Butowski N, Tihan T, Bollen AW, Phillips JJ, Wiita AP, Yeh I, Jacobson MP, Bastian BC, Perry A, Solomon DA. A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Nat Commun. 2018 02 23; 9(1):810.
    View on PubMed
  18. Iorgulescu JB, Van Ziffle J, Stevers M, Grenert JP, Bastian BC, Chavez L, Stichel D, Buchhalter I, Samuel D, Nicolaides T, Banerjee A, Mueller S, Gupta N, Tihan T, Bollen AW, Northcott PA, Kool M, Pfister S, Korshunov A, Perry A, Solomon DA. Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation. Acta Neuropathol. 2018 04; 135(4):635-638.
    View on PubMed
  19. Pekmezci M, Stevers M, Phillips JJ, Van Ziffle J, Bastian BC, Tsankova NM, Kleinschmidt-DeMasters BK, Rosenblum MK, Tihan T, Perry A, Solomon DA. Multinodular and vacuolating neuronal tumor of the cerebrum is a clonal neoplasm defined by genetic alterations that activate the MAP kinase signaling pathway. Acta Neuropathol. 2018 03; 135(3):485-488.
    View on PubMed
  20. Villanueva-Meyer JE, Wood MD, Choi BS, Mabray MC, Butowski NA, Tihan T, Cha S. MRI Features and IDH Mutational Status of Grade II Diffuse Gliomas: Impact on Diagnosis and Prognosis. AJR Am J Roentgenol. 2018 Mar; 210(3):621-628.
    View on PubMed

Go to UCSF Profiles, powered by CTSI