University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Erik Ullian, PhD

Erik Ullian, PhD

Associate Professor of Ophthalmology and Physiology, UCSF

Cancer Center Program Memberships

Neurologic Oncology | Pediatric Malignancies

Education

University of Chicago, Chicago, Ill, BA, 1991, Biological Science
University California San Francisco, CA, Ph.D., 1997, Neuroscience
Stanford University, Postdoc, 2004, Neurobiology


Professional Experience

  • 1998-2004
    Postdoc, Department of Neurobiology, Stanford University, Ben Barres
  • 2004-2010
    Assistant Professor of Ophthalmology and Physiology, UCSF
  • 2010-present
    Associate Professor of Ophthalmology and Physiology, UCSF

Honors & Awards

  • 2001
    Epilepsy training grant award
  • 2002
    Zaffaroni research fellowship in addiction research
  • 2004
    Sandler Award
  • 2005
    Alfred P. Sloan Fellowship
  • 2006
    March of Dimes Basil O’Connor Award
  • 2006
    Research to Prevent Blindness- New Investigator Award
  • 2009
    NIH New Innovator Award
  • 2014
    Walt and Lilly Disney Award for Amblyopia Research, RPB
  • 2015
    Allen Distnguished Investigator Award, Paul G Allen Foundation

Selected Publications

  1. Retallack H, Di Lullo E, Arias C, Knopp KA, Laurie MT, Sandoval-Espinosa C, Mancia Leon WR, Krencik R, Ullian EM, Spatazza J, Pollen AA, Mandel-Brehm C, Nowakowski TJ, Kriegstein AR, DeRisi JL. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016 Dec 13; 113(50):14408-14413.
    View on PubMed
  2. Ou Y, Jo RE, Ullian EM, Wong RO, Della Santina L. Selective Vulnerability of Specific Retinal Ganglion Cell Types and Synapses after Transient Ocular Hypertension. J Neurosci. 2016 Aug 31; 36(35):9240-52.
    View on PubMed
  3. Josowitz R, Mulero-Navarro S, Rodriguez NA, Falce C, Cohen N, Ullian EM, Weiss LA, Rauen KA, Sobie EA, Gelb BD. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports. 2016 Sep 13; 7(3):355-369.
    View on PubMed
  4. Krencik R, van Asperen JV, Ullian EM. Human astrocytes are distinct contributors to the complexity of synaptic function. Brain Res Bull. 2017 Mar; 129:66-73.
    View on PubMed
  5. Etxeberria A, Hokanson KC, Dao DQ, Mayoral SR, Mei F, Redmond SA, Ullian EM, Chan JR. Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity. J Neurosci. 2016 Jun 29; 36(26):6937-48.
    View on PubMed
  6. Rooney GE, Goodwin AF, Depeille P, Sharir A, Schofield CM, Yeh E, Roose JP, Klein OD, Rauen KA, Weiss LA, Ullian EM. Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. J Neurosci. 2016 Jan 06; 36(1):142-52.
    View on PubMed
  7. Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney GE, Rauen KA, Weiss LA, Rowitch DH, Ullian EM. Dysregulation of astrocyte extracellular signaling in Costello syndrome. Sci Transl Med. 2015 May 06; 7(286):286ra66.
    View on PubMed
  8. Shen YA, Chen Y, Dao DQ, Mayoral SR, Wu L, Meijer D, Ullian EM, Chan JR, Lu QR. Phosphorylation of LKB1/Par-4 establishes Schwann cell polarity to initiate and control myelin extent. Nat Commun. 2014 Sep 26; 5:4991.
    View on PubMed
  9. Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, Madireddy L, Chan JR, Baranzini SE, Ullian EM, Rowitch DH. Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature. 2014 May 08; 509(7499):189-94.
    View on PubMed
  10. Krencik R, Ullian EM. A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies. Front Cell Neurosci. 2013; 7:25.
    View on PubMed
  11. Hsu R, Schofield CM, Dela Cruz CG, Jones-Davis DM, Blelloch R, Ullian EM. Loss of microRNAs in pyramidal neurons leads to specific changes in inhibitory synaptic transmission in the prefrontal cortex. Mol Cell Neurosci. 2012 Jul; 50(3-4):283-92.
    View on PubMed
  12. Molofsky AV, Krencik R, Krenick R, Ullian EM, Ullian E, Tsai HH, Deneen B, Richardson WD, Barres BA, Rowitch DH. Astrocytes and disease: a neurodevelopmental perspective. Genes Dev. 2012 May 01; 26(9):891-907.
    View on PubMed
  13. Beaudoin GM, Schofield CM, Nuwal T, Zang K, Ullian EM, Huang B, Reichardt LF. Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampus. J Neurosci. 2012 Jan 04; 32(1):99-110.
    View on PubMed
  14. Koch SM, Dela Cruz CG, Hnasko TS, Edwards RH, Huberman AD, Ullian EM. Pathway-specific genetic attenuation of glutamate release alters select features of competition-based visual circuit refinement. Neuron. 2011 Jul 28; 71(2):235-42.
    View on PubMed
  15. Babiarz JE, Hsu R, Melton C, Thomas M, Ullian EM, Blelloch R. A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing. RNA. 2011 Aug; 17(8):1489-501.
    View on PubMed
  16. Schofield CM, Hsu R, Barker AJ, Gertz CC, Blelloch R, Ullian EM. Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex. Neural Dev. 2011 Apr 05; 6:11.
    View on PubMed
  17. Koch SM, Ullian EM. Neuronal pentraxins mediate silent synapse conversion in the developing visual system. J Neurosci. 2010 Apr 14; 30(15):5404-14.
    View on PubMed
  18. Okerlund ND, Kivimäe S, Tong CK, Peng IF, Ullian EM, Cheyette BN. Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain. J Neurosci. 2010 Mar 24; 30(12):4362-8.
    View on PubMed
  19. Barker AJ, Ullian EM. Astrocytes and synaptic plasticity. Neuroscientist. 2010 Feb; 16(1):40-50.
    View on PubMed
  20. Arikkath J, Peng IF, Ng YG, Israely I, Liu X, Ullian EM, Reichardt LF. Delta-catenin regulates spine and synapse morphogenesis and function in hippocampal neurons during development. J Neurosci. 2009 Apr 29; 29(17):5435-42.
    View on PubMed

Go to UCSF Profiles, powered by CTSI