University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Kyle Walsh, PhD

Kyle Walsh, PhD

Assistant Professor, School of Medicine, Department of Neurological Surgery, UCSF

Education

The Ohio State University, BS, 06/07, Molecular Genetics
The Ohio State University, BS, 06/07, Anthropology
The Yale University School of Medicine, PhD, 06/11, Genetic Epidemiology
The University of California, San Francisco, Postdoctoral, 08/13, Cancer Genetics
 

Professional Experience

  • 2005-2007
    The Ohio State University James Cancer Center, Clinical Research Associate, Department of Clinical Cancer Genetics
  • 2009-2011
    The Yale University School of Public Health, Research Associate, Center for Perinatal, Pediatric and Environmental Epidemiology
  • 2011-2013
    The University of California, San Francisco, Postdoctoral Scholar, Program in Cancer Genetics, Department of Epidemiology and Biostatistics
  • 2013-Present
    The University of California, San Francisco, Assistant Professor, Division of Neuroepidemiology, Dept. of Neurological Surgery

Honors & Awards

  • 2014
    Award for Excellence in Epidemiology Research
  • 2013
    Marvin Barker Award, The Society for Neuro-OncologyUCSF Brain Tumor Research Center
  • 2011, 2013
    BTEC Junior Investigator Award,, The Brain Tumor Epidemiology Consortium2011
    BTEC Junior Investigator Award, The Brain Tumor Epidemiology Consortium
  • 2011
    Master's degree awarded "With Distinction", The Yale University School of Public Health
  • 2007
    University Fellowship, The Yale University School of Public Health
  • 2007
    Outstanding Student Presentation in Human Genetics, American Association for Anthropological Genetics

Selected Publications

  1. Hayes J, Yu Y, Jalbert LE, Mazor T, Jones LE, Wood MD, Walsh KM, Bengtsson H, Hong C, Oberndorfer S, Roetzer T, Smirnov IV, Clarke JL, Aghi MK, Chang SM, Nelson SJ, Woehrer A, Phillips JJ, Solomon DA, Costello JF. Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas. Neuro Oncol. 2018 Apr 09; 20(5):632-641.
    View on PubMed
  2. Wiemels JL, Walsh KM, de Smith AJ, Metayer C, Gonseth S, Hansen HM, Francis SS, Ojha J, Smirnov I, Barcellos L, Xiao X, Morimoto L, McKean-Cowdin R, Wang R, Yu H, Hoh J, DeWan AT, Ma X. GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. Nat Commun. 2018 01 18; 9(1):286.
    View on PubMed
  3. Wallace AD, Francis SS, Shao X, de Smith AJ, Walsh KM, Mckean-Cowdin R, Ma X, Dahl G, Barcellos LF, Wiemels JL, Metayer C. A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology. Haematologica. 2018 Jan; 103(1):e29-e31.
    View on PubMed
  4. Zhang C, de Smith AJ, Smirnov IV, Wiencke JK, Wiemels JL, Witte JS, Walsh KM. Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma. J Neurooncol. 2017 Nov; 135(2):237-244.
    View on PubMed
  5. Bazyka D, Finch SC, Ilienko IM, Lyaskivska O, Dyagil I, Trotsiuk N, Gudzenko N, Chumak VV, Walsh KM, Wiemels J, Little MP, Zablotska LB. Buccal mucosa micronuclei counts in relation to exposure to low dose-rate radiation from the Chornobyl nuclear accident and other medical and occupational radiation exposures. Environ Health. 2017 06 23; 16(1):70.
    View on PubMed
  6. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study. JAMA Oncol. 2017 May 01; 3(5):636-651.
    View on PubMed
  7. Pekmezci M, Rice T, Molinaro AM, Walsh KM, Decker PA, Hansen H, Sicotte H, Kollmeyer TM, McCoy LS, Sarkar G, Perry A, Giannini C, Tihan T, Berger MS, Wiemels JL, Bracci PM, Eckel-Passow JE, Lachance DH, Clarke J, Taylor JW, Luks T, Wiencke JK, Jenkins RB, Wrensch MR. Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT. Acta Neuropathol. 2017 Jun; 133(6):1001-1016.
    View on PubMed
  8. de Smith AJ, Kaur M, Gonseth S, Endicott A, Selvin S, Zhang L, Roy R, Shao X, Hansen HM, Kang AY, Walsh KM, Dahl GV, McKean-Cowdin R, Metayer C, Wiemels JL. Correlates of Prenatal and Early-Life Tobacco Smoke Exposure and Frequency of Common Gene Deletions in Childhood Acute Lymphoblastic Leukemia. Cancer Res. 2017 04 01; 77(7):1674-1683.
    View on PubMed
  9. Francis SS, Wallace AD, Wendt GA, Li L, Liu F, Riley LW, Kogan S, Walsh KM, de Smith AJ, Dahl GV, Ma X, Delwart E, Metayer C, Wiemels JL. In utero cytomegalovirus infection and development of childhood acute lymphoblastic leukemia. Blood. 2017 03 23; 129(12):1680-1684.
    View on PubMed
  10. Endicott AA, Morimoto LM, Kline CN, Wiemels JL, Metayer C, Walsh KM. Perinatal factors associated with clinical presentation of osteosarcoma in children and adolescents. Pediatr Blood Cancer. 2017 Jun; 64(6).
    View on PubMed
  11. de Smith AJ, Ojha J, Francis SS, Sanders E, Endicott AA, Hansen HM, Smirnov I, Termuhlen AM, Walsh KM, Metayer C, Wiemels JL. Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia. Oncotarget. 2016 Nov 08; 7(45):72733-72745.
    View on PubMed
  12. Ohba S, Mukherjee J, Johannessen TC, Mancini A, Chow TT, Wood M, Jones L, Mazor T, Marshall RE, Viswanath P, Walsh KM, Perry A, Bell RJ, Phillips JJ, Costello JF, Ronen SM, Pieper RO. Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process. Cancer Res. 2016 11 15; 76(22):6680-6689.
    View on PubMed
  13. Gonseth S, de Smith AJ, Roy R, Zhou M, Lee ST, Shao X, Ohja J, Wrensch MR, Walsh KM, Metayer C, Wiemels JL. Genetic contribution to variation in DNA methylation at maternal smoking-sensitive loci in exposed neonates. Epigenetics. 2016 09; 11(9):664-673.
    View on PubMed
  14. Ojha J, Codd V, Nelson CP, Samani NJ, Smirnov IV, Madsen NR, Hansen HM, de Smith AJ, Bracci PM, Wiencke JK, Wrensch MR, Wiemels JL, Walsh KM. Genetic Variation Associated with Longer Telomere Length Increases Risk of Chronic Lymphocytic Leukemia. Cancer Epidemiol Biomarkers Prev. 2016 07; 25(7):1043-9.
    View on PubMed
  15. Walsh KM, Whitehead TP, de Smith AJ, Smirnov IV, Park M, Endicott AA, Francis SS, Codd V. Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. Carcinogenesis. 2016 06; 37(6):576-582.
    View on PubMed
  16. Endicott AA, Taylor JW, Walsh KM. Telomere length connects melanoma and glioma predispositions. Aging (Albany NY). 2016 Mar; 8(3):423-4.
    View on PubMed
  17. David SP, Wang A, Kapphahn K, Hedlin H, Desai M, Henderson M, Yang L, Walsh KM, Schwartz AG, Wiencke JK, Spitz MR, Wenzlaff AS, Wrensch MR, Eaton CB, Furberg H, Mark Brown W, Goldstein BA, Assimes T, Tang H, Kooperberg CL, Quesenberry CP, Tindle H, Patel MI, Amos CI, Bergen AW, Swan GE, Stefanick ML. Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans. EBioMedicine. 2016 Feb; 4:153-61.
    View on PubMed
  18. Walsh KM, Ohgaki H, Wrensch MR. Epidemiology. Handb Clin Neurol. 2016; 134:3-18.
    View on PubMed
  19. Walsh KM, Codd V, Rice T, Nelson CP, Smirnov IV, McCoy LS, Hansen HM, Elhauge E, Ojha J, Francis SS, Madsen NR, Bracci PM, Pico AR, Molinaro AM, Tihan T, Berger MS, Chang SM, Prados MD, Jenkins RB, Wiemels JL. Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk. Oncotarget. 2015 Dec 15; 6(40):42468-77.
    View on PubMed
  20. de Smith AJ, Walsh KM, Hansen HM, Endicott AA, Wiencke JK, Metayer C, Wiemels JL. Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA. PLoS One. 2015; 10(11):e0143343.
    View on PubMed

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