Shichun Zheng, MD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Shichun Zheng, MD

Assistant Adjunct Professor, Department of Neurological Surgery, UCSF

shichun.zheng@ucsf.edu

Phone: (415) 502-1678
Box 0441, UCSF
San Francisco, CA 94143-0441

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Cancer Center Membership

Associate Member » Neurologic Oncology» Cancer Genetics

Education

Xian Medical University, China, MD, 1977, Medicine
Xian Medical University, China, MS, 1987, Medical Parasitology


Professional Experience

  • 1992-94
    Postgraduate Researcher, Dept. of Medicine, University of California San Francisco (UCSF)
  • 1994-96
    Junior Specialist, Dept. of Dermatology, UCSF
  • 1996-98
    Assistant Specialist, Dept. of Epidemiology and Biostatistics, UCSF
  • 1998-00
    Associate Specialist, Dept. of Epidemiology and Biostatistics, UCSF
  • 2000-05
    Specialist, Dept. of Epidemiology and Biostatistics, UCSF
  • 2005-present
    Assistant Adjunct Professor, Department of Neurological Surgery, UCSF

Honors & Awards

  • 1992-94
    Sir Run Run Shaw Scholarship

Selected Publications

  1. Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med. 2015 Jun 25; 372(26):2499-508.
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  2. Serum macrophage-derived chemokine/CCL22 levels are associated with glioma risk, CD4 T cell lymphopenia and survival time. Int J Cancer. 2015 Aug 15; 137(4):826-36.
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  3. A comparison of DNA methylation specific droplet digital PCR (ddPCR) and real time qPCR with flow cytometry in characterizing human T cells in peripheral blood. Epigenetics. 2014 Oct 3; 9(10):1360-5.
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  4. Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. Nat Genet. 2014 Jul; 46(7):731-5.
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  5. Direct and indirect targets of the E2A-PBX1 leukemia-specific fusion protein. PLoS One. 2014; 9(2):e87602.
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  6. Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis. Neuro Oncol. 2013 Aug; 15(8):1041-7.
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  7. Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma. PLoS One. 2013; 8(2):e57610.
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  8. Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology. Neuro Oncol. 2013 May; 15(5):535-41.
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  9. Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studies. Genet Epidemiol. 2013 Feb; 37(2):222-8.
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  10. Epigenetic biomarkers of T-cells in human glioma. Epigenetics. 2012 Dec 1; 7(12):1391-402.
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  11. A global DNA methylation and gene expression analysis of early human B-cell development reveals a demethylation signature and transcription factor network. Nucleic Acids Res. 2012 Dec; 40(22):11339-51.
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  12. PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome. Neuro Oncol. 2012 Sep; 14(9):1146-52.
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  13. DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression. Neuro Oncol. 2011 Mar; 13(3):280-9.
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  14. TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a. Blood. 2010 Dec 2; 116(23):4885-93.
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  15. Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma. Neuro Oncol. 2007 Jul; 9(3):271-9.
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  16. Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia. Cancer Res. 2004 Mar 15; 64(6):2000-6.
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