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Helen Diller Family Compr Cancer Ctr
JAMES L. RUBENSTEIN, MD, PHD

Assistant Professor of Medicine in Residence, UCSF

CONTACT

(415) 353-2421 (appts)

Box 1270, UCSF; San Francisco, CA 94143-1270

additional websites:

UCSF Physician Referral Directory

EDUCATION

Stanford University, B.S., June 1985, Biological Sciences
The Rockefeller University, Ph.D., June 1991, Molecular and Cellular Neuroscience (Medical Scientist Training Program)
Cornell University Medical College, M.D., May 1992, Medicine
Stanford University Medical Center, Stanford, CA, Internship/Residency, 1992-1995, Internal Medicine
University of California, San Francisco, San Francisco, CA, Fellowship, 1992-1998, Hematology/Oncology and Neuro-Oncology

PROFESSIONAL EXPERIENCE

1998-2006

Assistant Adjunct Professor of Medicine, Attending Physician in Hematology/Oncology, University of California, San Francisco

2006-present

Assistant Professor of Medicine in Residence

HONORS & AWARDS

1985

Phi Beta Kappa

1985

Departmental Honors, Biological Sciences

1985

Honors in Humanities

1995

Housestaff Research Award

1998

Young Investigator Award, Amer. Soc'y of Clinical Oncology

1999

American Brain Tumor Association Fellowship

2000

UCSF/Mt Zion Clinical Investigator Research Program Award

2000

Clinical Scientist Development Award (CA Cancer Research Program)

2001

UCSF/Mt Zion Clinical Investigator Research Program Award

2001

Career Development Award (American Society of Clinical Oncology)

2001

Accelerate Brain Cancer Cure Foundation Award

2002

UCSF Research Evaluation and Allocation Committee Award

2003

UC Discovery Grant

2003

IDEA Award (CA Tobacco-Related Disease Research Program)

2004

National Cancer Institute Research Career Award

2004

American Cancer Society Award

2005

NCI Brain Tumor SPORE Developmental Research Award

2006

Canary Fund Early Detection Award

2006

NCI Brain Tumor SPORE Developmental Research Award

SELECTED PUBLICATIONS

Rubenstein, J.L., Greengard, P., and Czernik, A.J. 1993. Calcium-Dependent Serine Phosphorylation of Synaptophysin. Synapse 13, 161-172.

Benfenati, F., Valtorta, F., Rubenstein, J.L., Gorelick, F.S., Greengard, P., and Czernik, A.J. 1992. Synaptic Vesicle-Associated Ca2+/Calmodulin-Dependent Protein Kinase II is a Binding Protein for Synapsin I. Nature 359: 417-420.

Rubenstein, J.L. and Yaari, H. 1993. Von Hippel-Lindau and the Genetics of Astrocytoma. J. Natl. Cancer Inst. 86(2) 142-143

Ng, S., Tse, V.C., Rubenstein, J.L., Bradford, E., Enzmann, D.R., and Conley, F.K. 1995. Progressive Multifocal Leukoencephelopathy: Unusual MR Findings. J. Computer Assisted Tomography. 19(2) 302-305.

Rubenstein, E., Giacomini, J.C., Gordon, H.J., Rubenstein, J.L., Brown, G. 1995. Xenon K-edge Dichromographic Bronchography: Synchrotron Radiation Based Medical Imaging. Nuclear Instruments and Methods in Physics Research A365, 360-361

Rubenstein, J.L., Kim, J., Ozawa, T., Zhang, M., Westphal, M., Deen, D., and Shuman, M.A. 2000. Anti-VEGF Treatment of Glioblastoma Prolongs Survival But Results in Increased Vascular Cooption. Neoplasia. 2(4) 306-314

Rubenstein, J.L, Fischbein, N., Aldape, K., Burton, E., and Shuman, M. Hemorrhage and VEGF Expression in a Case of Primary Central Nervous System Lymphoma: Role of Vascular Endothelial Growth Factor. 2002. J. Neuro-Oncology 58(1)53-56.

Rubenstein, J.L., Combs, J. Rosenberg, Levy, A., McDermott, M., Damon, L., Ignoffo, R., Aldape, K., Shen, A., Lee, D.,Grillo-Lopez, A. and M.A. Shuman Rituximab in CNS Lymphoma: Targeting the Leptomeningeal Compartment. Blood, 2003 Jan 15;101(2):466-8.

Shenkier, T., Blay, J-Y, O'Neill, B, Poortmans, P, Thiel, E., Jahnke, K., Abrey, L., Neuwelt, E., Tsang, R., Batchelor, T., Harris, N., Ferreri, A., Ponzoni, M., O'Brien, P., Rubenstein, J.L. and Connors, J.M. Primary Central Nervous System Lymphoma of T cell origin: A Descriptive Analysis. Journal of Clinical Oncology. J Clin Oncol. 2005 Apr 1;23(10):2233-9.

Rubenstein, J., Treseler, P and O'Brien, J. Pathology and Genetics of Primary CNS Lymphoma. Hematology/Oncology Clinics of North America. 2005 19(4): 705-717.

Rubenstein, J., Fridlyand, J., Shen, A., Aldape, K., Ginzinger, D.,Batchelor, T., Treseler, P., Berger, M., McDermott, M., Prados, M., Karch, J., Okada, C., Hyun, W., Parikh, S., Haqq, C., Shuman, M. Gene Expression and Angiotropism in Primary CNS Lymphoma. Blood, 2006 107(9): 3716-3723.

Kadoch, C., Treseler, P., and Rubenstein, J. Molecular Pathogenesis of Primary CNS Lymphoma. Neurosurg. Focus. 2006. (5). 1-5.

Rubenstein, J., Fridlyand, J., Abrey, L., Shen, A., Karch, J., Wang, E., Issa,ĘS., Damon, L., Prados, M., McDermott, M., O'Brien, J., Haqq, C., and Shuman, M. Phase I Study of Intraventricular Administration of Rituximab in Patients with Recurrent CNS and Intraocular Lymphoma. J Clin Oncol. 2007 Feb 20; [Epub ahead of print]

Book Chapters

Pathophysiology of Disease: An Introduction to Clinical Medicine, 4th ed. 2002. Neoplasia. Tripathy, D and Rubenstein, J.L. McGraw Hill Press

Intracranial Metastases. Sawaya, R. Brain Metastases from Genitourinary Cancer: Germ Cell, Testicular, Prostate and Bladder Cancer Theodosopoulos, P., Rubenstein, J.L. and McDermott in 2004. Blackwell Publishing.

Clinical Oncology 3rd ed. Abeloff, M., Armitrage, J., Lichter, A. and Niederhuber J. Brain Metastases and Carcinomatous Meningitis. Huang, K., Sneed, P, and Rubenstein, J.L. 2004. Elsevier Churchill Livingstone Press.

Cancer, Principles and Practice of Oncology 7th ed. DeVita, V., Hellman, S., and Rosenberg, S. Metastatic Brain Cancer Larson, D.A., Rubenstein, J.L., McDermott, M. 2005, Lippincott-Raven

Viral and Immunologic Malignancies, Palefsky, J. and Volberding, P. Management of Primary CNS Lymphoma and Intraocular Lymphoma. Rubenstein, J.L. and Berger, M.S. 2006, BC Decker

2/25/07

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