dschild@lbl.gov
(510) 486-6013 (voice)
(510) 486-6816 (fax)

Box 0628, UCSF; San Francisco, CA 94143-0628

additional websites:

Schild Department Profile

Cornell University, B.A., 1973, Biology
University of Washington, Ph.D., 1978, Genetics
University of California, Berkeley, Postdoc, 1978-1982, Genetics & Mol. Biol

Schild, D. Meiotic effects of the cdc mutations of S. cerevisiae, Univ. of Washington, Ph.D. thesis, 1978.

Schild, D. and B. Byers. Meiotic effects of DNA-defective cell division cycle mutations of Saccharomyces cerevisiae, Chromosoma, (Berl.) 70: 109-130, 1978.

Mortimer, R.K. and D. Schild. The genetic map of S. cerevisiae, Microbiol. Reviews, 44: 519-571, 1980.

Schild, D. and B. Byers. Diploid spore formation and other meiotic effects of two cell division cycle mutations of Saccharomyces cerevisiae, Genetics 96: 859-876, 1981.

Schild, D., H.N. Ananthaswamy and R.K. Mortimer, An endomitotic effect of a cell cycle mutation of Saccharomyces cerevisiae, Genetics 97: 551-562, 1981.

Mortimer, R.K. and D. Schild. Genetic mapping in Saccharomyces cerevisiae, Molecular Biology of Saccharomyces, Cold Spring Harbor Monogram, Vol. 1, 11-26, 1981.

Mortimer, R.K., R. Contopoulou and D. Schild. Mitotic chromosome loss in radiation sensitive strains of the yeast, Saccharomyces cerevisiae, Proc. Nat. Acad. Sci. (USA), 78: 5778-5782, 1981.

Mortimer, R.K. and D. Schild. Genetic map of Saccharomyces cerevisiae, Molecular Biology of Saccharomyces: Metabolism and Gene Expression, Cold Spring Harbor Lab., 639-650, 1982.

Schild, D., B. Konforti, C. Perez, W. Gish and R.K. Mortimer. Isolation and characterization of yeast DNA repair genes: I. Cloning of the rad52 gene, Current Genetics 7: 85-92, 1983.

Schild, D., I.L. Calderon, C.R. Contopoulou and R.K. Mortimer. Cloning of yeast recombination repair genes and evidence that several are nonessential genes. In: Cellular Responses to DNA Damage. Alan R. Liss, Inc., New York, pp. 417-427, 1983.

Schild, D., J. Johnston, C. Chang and R.K. Mortimer. Cloning and mapping of the yeast photoreactivation gene PHR1, Mol. Cell Biol. 4: 1864-1870, 1984.

Mortimer, R.K., and D. Schild. Genetic map of Saccharomyces cerevisiae,Edition 9, Microbiological Reviews, 49: 181-212, 1985.

Schild, D. and R.K. Mortimer. A mapping method for Saccharomyces cerevisiae using RAD52-induced chromosome loss, Genetics 110: 569-589, 1985.

Cole, G.M., D. Schild, S.T. Lovett and R.K. Mortimer. Regulation of RAD54 and RAD52-lacZ gene fusions in S. cerevisiae in response to DNA damage, Mol. Cell. Biol. 7: 1078-1084, 1987.

Cole, G.M., D. Schild, and R.K. Mortimer. Two DNA repair and recombination genes in Saccharomyces cerevisiae, RAD52 and RAD54, are induced during meiosis. Mol. Cell Biol. 9: 3101-3104, 1989.

Mortimer, R.K., D. Schild, C.R. Contopoulou and J. Kans. Genetic map of Saccharomyces cerevisiae. Edition 10, Yeast 5: 321-404, 1989.

Schild, D., A. Brake, M. Kiefer, D. Young and P. Barr. Cloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutations, PNAS 87: 2916-20, 1990.

Mortimer, R.K., D. Schild, C.R. Contopoulou and J. Kans. Genetic and physical maps of Saccharomyces cerevisiae, Methods in Enzym. 194: 827-863, 1990.

Patterson, D., D. Schild and L Lai. Translocations and rearrangements involving chromosome 21. Prog. Clinical Biol. Research 360: 27-37, 1990.

Gnirke, A., T. Barnes, D. Patterson, D. Schild, T. Featherstone and M. Olson. Cloning and in vivo expression of the human GART gene using yeast artificial chromosomes. EMBO 10: 1629-34, 1991.

Emery, J., D. Schild, D.E. Kellogg and R.K. Mortimer. Sequence of RAD54, a Saccharomyces cerevisiae gene involved in recombination and repair. Gene 104: 103-106, 1991.

Chang, F.H., T.S. Barnes, D. Schild, A. Gnirke, J. Bleskan and D. Patterson. Expression of a human cDNA encoding a protein containing GARS, AIRS and GART corrects the defects in mutant chinese hamster overy cells lacking these activities. Somat. Cell and Molec. Genet. 17: 411-420, 1991.

Schild, D., B.J. Glassner, R.K. Mortimer, M. Carlson and B.C. Laurent. Identification of RAD16, a yeast excision repair gene homologous to the recombinational repair gene RAD54 and to the SNF2 gene involved in transcriptional activation. Yeast 8: 385-395, 1992.

Schild, D. Genetic analysis of a new rad52 allele in yeast which is suppressed by srs2 and ccr4 mutations, mating type heterozygosity, or over-expression of RAD51. Genetics 140: 115-127, 1995.

Dosanjh, M., D.W. Collins, W. Fan, G.G. Lennon, J. Albala, Z. Shen and D. Schild. Analysis of RAD51C, a new human member of the RAD51 family of related genes. Nucleic Acids Res. 26: 1179-1184, 1998.

Liu, N., J.E. Lamerdin, R.S. Tebbs, D. Schild, J.D. Tucker, M.R. Shen, K.W. Brookman, M.J. Siciliano, C.A. Walter, W. Fan, L.S. Narayana, Z.Q. Zhou, A.W. Adamson, K.J. Sorensen, D.J. Chen, N.J. Jones and L.H. Thompson. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA crosslinks and other damages. Mol. Cell 1: 783-793, 1998.

Thompson, L.H. and D. Schild. The contribution of homologous recombination in preserving genome integrity in mammalian cells. Biochemie 81: 87-105, 1999.

Schild, D., Y. Lio, D.W. Collins, T. Tsomondo and D.J. Chen. Evidence for simultaneous protein interactions between human RAD51 paralogs. J. Biol. Chem. 275: 16443-16449, 2000.

Thompson, L.H. and D. Schild. Homologous recombinational repair of DNA ensures chromosome stability in mammalian cells . Mut. Research 477: 131-153, 2001.

Takata, M., M.S. Sasaki, S. Tachiiri, T. Fukushima, E. Sonoda, D. Schild, L.H. Thompson and S. Takeda. Five Rad51 paralogs: a functional unit that stabilizes chromosomes by recombinational DNA repair. Mol. Cell. Biol. 21: 2858-2866, 2001.

Sigurdsson, S., S. Von Komen, W. Bussen, D. Schild, J. Albala, and P. Sung. Mediator Function of the Human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA Strand Exchange. Genes and Dev. 15: 3308-3318, 2001.

Wiese, C., D.W. Collins, J.S. Albala, L.H. Thompson, A. Kronenberg and D. Schild. Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells. Nucleic Acid Res. 30: 1001-1008, 2002.

Miller, K.A. , D.M. Yoshikawa, I.R. McConnell, R. Clark, D. Schild, and J.S. Albala. RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51. J. Biol. Chem. 277: 8406-8411, 2002.

Liu, N., D. Schild, M.P. Thelen, and L.H. Thompson. Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells. Nucleic Acid Res. 30: 1009-1015, 2002.

Thompson, L.H. and D. Schild. Recombinational DNA Repair and Human Disease. Mut. Research 509: 49-78, 2002.

Lio, Y.C., D. Schild, M. A. Brenneman, J L. Redpath, and D. J. Chen. Human Rad51C deficiency destabilizes XRCC3, impairs recombination and radiosensitizes S/G2-phase cells. J. Biol. Chem. In press, 2004 (available at the JBC web site).

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