Stanford W. Ascherman and Norman R. Ascherman Chair in Hematology-Oncology, UCSF
Professor in Residence, Medicine and Urology, UCSF
Director, Investigational Therapeutics, and Co-Leader, Prostate Cancer Program, UCSF Helen Diller Family Comprehensive Cancer Center
| CONTACT | |
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(415) 353-7171 (appts) Box 1711, UCSF; San Francisco, CA 94143-1711 |
additional websites: |
| EDUCATION | |
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Stanford University, Stanford, CA, BS, 1980, Biology
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| PROFESSIONAL EXPERIENCE | |
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1983-1983 |
Research Fellow, Div. of Hematology/Oncology,Case Western ReserveUniversity, Cleveland, OH |
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1982-1983 |
Pathology Fellowship, Department of Pathology, Case Western Reserve University, Cleveland, OH |
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1985-1988 |
Internal Medicine Internship and Residency Training Program, Beth Israel Hospital, Boston, MA |
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1988-1989 |
Clinical Fellow, Cancer Research Institute, University of California, San Francisco, CA |
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1989-1991 |
Research Fellow, Cancer Research Institute, (Dr. Marc Shuman) University of California, San Francisco, CA |
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1991-1997 |
Assistant Clinical Professor of Medicine, University of California, San Francisco, CA |
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1991-present |
Head, Urologic Medical Oncology Section, Division of Hematology/Oncology, Univ. of California, San Franciso |
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1996-present |
Co-Director, Urologic Oncology Program, University of California, San Francisco, CA |
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1997-2001 |
Associate Clinical Professor of Medicine and Urology, University of California, San Francisco, CA |
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1999-present |
Chair, GenitoUrinary Committee, Cancer and Leukemia Group B (CALGB) |
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2001-present |
Clinical Professor of Medicine and Urology, University of California, San Francisco, CA |
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2007-present |
Stanford W. Ascherman and Norman R. Ascherman Endowed Chair, UCSF, San Francisco, CA |
| HONORS & AWARDS | |
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1984 |
Alpha Omega Alpha Honor Medical Society |
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1997 |
Prostate Cancer Foundation Therapy Consortium |
| SELECTED PUBLICATIONS | |
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(From 175) | |
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Small EJ, Fratesi P, Reese DM, Strang G, Laus R, Peshwa M, Valone FH. Immunotherapy of hormone refractory prostate cancer with antigen-loaded dendritic cells. J Clin Oncol 18:3894, 2000. | |
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Small EJ, Reese DM, Frohlich M, Bok R, Shinohara K, Grossfeld G, Kelly WK. A prospective trial of the herbal supplement PC-SPES in patients with progressive prostate cancer. J Clin Oncol 18:3595, 2000. | |
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Reese DM, Fratesi P, Corry M, Novotny W, Small EJ. A phase II trial of humanizedanti-VEGF antibody for the treatment of androgen-independent prostate cancer. The Prostate Journal 3:2, 2001. | |
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Small EJ, McMillan A, Meyer M, Chen L, Slichenmyer WJ, Lenehan PF, Eisenberger M. Serum PSA decline as a marker of clinical outcome in hormone refractory prostate cancer patients: Association with progression-free survival, pain endpoints and survival. J Clin Oncol 19:1304, 2001. | |
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Kantoff PW, Farmer DA, Halabi S, Hayes DF, Vogelzang NJ, Small EJ. Prognostic significance of reverse transcriptase polymerase chain reaction (rt-PCR) for prostate specific antigen in men with hormone refractory prostate cancer. J Clin Oncol 19:3025, 2001. | |
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Small EJ, Halabi S, Ratain M, Rosner G, Ansari R, Palchak D, Marshall E, et al. A phase III study of three different doses of suramin administered with a fixed dosing schedule in patients with advanced prostate cancer: Results of CALGB 9480. J Clin Oncol 20:3369, 2002. | |
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Harris KA, Small EJ. Low-dose ketoconazole with replacement doses of hydrocortisone in patients with progressive androgen-independent prostate cancer. J Urol 168:542, 2002. | |
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Rini BI, Weinberg V, Bok RA, Small EJ. PSA kinetics as a measure of the biologic effect of granulocyte-macrophage colony stimulating factor in patients with serologic progression of prostate cancer. J Clin Oncol 21:99, 2003. | |
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Small EJ, Smith MR, Seaman J, Kowalski M. A multicenter, randomized, placebo-controlled study of pamidronate disodium for the palliation of bone pain in patients with advanced prostate cancer. J Clin Oncol 21:4277, 2003. | |
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Oh WK, Halabi S, Kelly WK, Werner C, Godley PA, Vogelzang NJ, Small EJ. A phase II study of estramustine, docetaxel and carboplatin with G-CSF support in patients with hormone refractory prostate cancer: Cancer and Leukemia Group B 99813. Cancer 98:2592, 2003. | |
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Taplin ME, Halabi S, Wods B, Picus J, Hayes DF, Kantoff P, Vogelzang NJ, Small EJ. Androgen receptor mutations in androden independent prostate cancer: CALGB 9663. J Clin Oncol 21:2678, 2003. | |
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Halabi S, Small EJ, Kantoff PW, Dawson NA, Vogelzang NJ. A prognostic model for predicting overall survival in men with hormone refractory metastatic prostate cancer. J Clin Oncol 21:1232, 2003. | |
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Halabi S, Small EJ, Hayes DF, Vogelzang NJ, Kantoff PW. The prognostic significance of reverse transcriptase polymerase chain reaction (rt-PCR) for prostate specific antigen in prostate cancer patients with one prior hormonal therapy: A nested study within CALGB 9583. J Clin Oncol 21:490, 2003. | |
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Small EJ, Halabi S, Dawson NA, Stadler WM, Rini BI, et al. A phase III trial of antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: Results of CALGB 9583. J.Clin Oncol 22:1025, 2004. | |
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Oh WK, Kantoff PW, Weinberg V, Jones G, Rini BI, Bok R, Smith MR, Bubley GJ, Rosen RT, DiPaola R, Small EJ. A prospective, multicenter, randomized phase II trial of the herbal supplement PC-SPES & diethylstilbestrol in patients with androgen-independent prostate cancer. J Clin Oncol 22:3707, 2004. | |
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Petrylak DP, Tangen CM, Hussain M, Lara PN, Jr., Jones JA, Small EJ, et al. Docetaxel and estramustine versus mitoxantrone and prednisone: Results of Southwest Oncology Group Intergroup Protocol 99-16. New Engl J Med 351:1513, 2004. | |
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Ryan CJ, Small EJ. Long-term response to ketoconazole as secondary hormonal therapy in prostate cancer. Am J Oncol Rev 3:471, 2004. | |
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Rini BI, Beinart G, Weinberg V, Small EJ. APC8015 (ProvengeŠ) in patients with androgen independent biochemically relapsed prostate cancer. Clin Prostate Cancer 4:55, 2005. | |
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Small EJ, Schellhammer P, Higano C, Redfern C, Nemunaitis J, Valone F, Jones L, Hershberg R. Results of a placebo-controlled phase III trial of immunologic therapy with Sipuleucel T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol 24:3089, 2006. | |
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Halabi S, Vogelzang NJ, Ou SS, Small EJ. Survival of octagenarians with hormone refractory prostate cancer: A pooled analysis of eight Cancer & Leukemia Group B (CALGB) studies. J Urol 176:81, 2006. | |
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Rini B, Fong L, Weinberg V, Conry S, Small E. Combination immunotherapy with prostatic acid phosphotase-pulsed antigen presenting cells plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy. Cancer 107:67, 2006. | |
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Wilding G, Soulie P, Trump D, Das-Gupta A, Small EJ. Results from a pilot trial of Geftinib (Iressa ZD19839) refractory prostate cancer. Cancer 106:1917, 2006. | |
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Rosenberg JE, Galsky MD, Weinberg VK, Oh WK, Kelly WK, Small EJ. A retrospective evaluation of second-line chemotherapy response in hormone refractory prostate cancer. Cancer 106:58, 2006. | |
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Rini BI, Fong L, Weinberg V, Kavanaugh B, Small EJ. Clinical and immunological characteristics of patients with serologic progression of prostate cancer achieving long-term disease control with granulocyte macrophage colony-stimulating factor. J Urol 175: 2087, 2006. |
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9/6/07 |
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