stopplerh@cc.ucsf.edu
(415) 476-0435 (voice)
(415) 476-8218 (fax)

Box 0808, UCSF; San Francisco, CA 94143-0808

University of Giessen, Germany, 1981-1984, Biology
University of Heidelberg, Germany, M.S., 1984-1988, Molecular Biology
University of Heidelberg, Germany, Ph.D., 1988-1992, Molecular Biology / Virology
Georgetown University School of Medicine, postdoc, 1992-1994, Tumor Biology

Rittner K, Stöppler H, Pawlita M, and Sczakiel G. Versatile eukaryotic vectors for strong and constitutive transient and stable gene expression. Methods in Molecular and Cellular Biology 1991 (2) 176-181.

Steuer B, Stöppler H, Breuer B, and Alonso A. Transcription of BPV-1 genes in transfected F9 cells. Oncogene 1992 (7) 1875-1878.

Steinmann KE, Pei XF, Stöppler H, Schlegel R, and Schlegel R. Elevated expression and activity of mitotic regulatory proteins in human papillomavirus-immortalized human keratinocytes. Oncogene 1994 (9) 387-394.

Stöppler H, Conrad Stöppler M, Adduci A, Koval D, and Schlegel R. The serine protease inhibitors TLCK and TPCK react with the Rb-binding core of the HPV-18 E7 protein and abolish its Rb-binding capability. Virology, 1996 (217), 542-553.

Stöppler H, Kirchhoff T, Alonso A, and Gissmann L. Influence of the Human Papillomavirus type 16 (HPV-16) gene expression on the in vitro differentiation of the Human Teratocarcinoma cell line 2102 Ep. Molecular Carcinogenesis, 1996 (16), 109-114.

Conrad Stöppler M, Ching K, Stöppler H, Clancy K, Schlegel R, and Icenogle J. Natural variants of the Human Papillomavirus type 16 (HPV-16) E6 protein differ in their ability to alter keratinocyte differentiation and to induce p53 degradation. Journal of Virology, 1996 (70), 6987-6993.

Stöppler H, Koval D, and Schlegel R. The serine protease inhibitors TLCK and TPCK inhibit the in vitro immortalization of primary human keratinocytes by HPV-18 DNA. Oncogene, 1996 (13), 1545-1548.

Araujo JC, Doniger J, Stöppler H, Sadaie RM, and Rosenthal LJ. Cell lines containing and expressing the human herpesvirus 6A ts gene are protected from both H-ras and BPV-1 transformation. Oncogene, 1997 (14), 937-943.

Stöppler H, Hartmann DP, Sherman L, and Schlegel R. The human papillomavirus type 16 E6 and E7 oncoproteins dissociate cellular telomerase activity from the maintenance of telomere length. Journal of Biological Chemistry, 1997 (20), 13332-13337.

Stöppler H, Conrad Stöppler M, Johnson E, Simbulan-Rosenthal CM, Smulson ME, Iyer S, Rosenthal D, and Schlegel R. The E7 protein of human papillomavirus type 16 sensitizes primary human keratinocytes to apoptosis. Oncogene, 1998 (17), 1207-1214.

Stöppler H, Conrad Stöppler M, Kisiela M, Holzbach A, Moll I, Houdek P, and Moll R. Telomerase activity of Merkel cell carcinomas and Merkel cell carcinoma-derived cell cultures. Archives of Dermatological Research, 2001 (293), 397-406.

Stöppler H, Malercyzk C, Block K, Aigner A, and Czubayko F. The human papillomavirus (HPV) 16 E6 oncoprotein leads to an increase in gene expression of the angiogenic switch molecule FGF-BP in non-immortalized human keratinocytes. Oncogene, 2001 (20) 7430-7436.

Möller A, Malerczyk C, Völker U, Stöppler H, and Maser E. Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis. Proteomics, 2002 (2) 697-705.

Kehmeier E, Rühl H, Voland B, Conrad Stöppler M, Androphy E, and Stöppler H. Cellular steady state levels of the "high risk" but not the "low risk" human papillomavirus (HPV) E6 proteins are controlled by proteasome-dependent degradation and independent of their p53 and E6AP binding capabilities. Virology, 2002 (299) 72-87.

Alfke H, Stöppler H, Nocken F, Heverhagen J, Kleb B, Czubayko F, and Klose KJ. In vitro MR Imaging of regulated gene expression. Radiology, 2003 (228) 488-492.

Greengauz-Roberts O, Stöppler H, Nomura S, Yamaguchi H, Goldenring JR, Podolsky RH, Lee JR, and Dynan WS. Saturation labeling with cysteine-reactive cyanine fluorescent dyes provides increased sensitivity for protein expression profiling of laser microdissected clinical specimens. Proteomics, 2005 (5) 1746-1757

Hsu. S, Dickinson DP, Qin H, Lapp C, Lapp D, Borke J, Walsh DS, Bollag WB, Stöppler H, Yamamoto T, Osaki T, Schuster G. Inhibition of Autoantigen Expression by (-)-Epigallocatechin-3-gallate (the Major Constituent of Green Tea) in Normal Human Cells. The Journal of Pharamcology and Experimental Therapeutics, 2005 (315) 805-811

Hsu S, Dickinson DP, Qin H, Borke J, Ogbureke K, Winger J, Camba A, Bollag WB, Stöppler H, Sharawy M, and Schuster G. Green Tea Polyphenols Reduce Autoimmune Symptoms in a Murine Model for Humans SjogrenÕs Syndrome and Protect Human Salivary Acinar Cells from TNF--Induced Cytotoxicity via p38 MAPK Activation. Autoimmunity, 2007 (40) 138-147

Stephen Hsu, Haiyan Qin, Douglas Dickinson, Ding Xie, Wendy B. Bollag, Hubert Stöppler, Henna Pearl, Anna Vu, Margaretta Watkins, Meredith Koehler, and George Schuster. Expression of caspase 14 reduces tumorigenicity of skin cancer cells. In Vivo, 2007 (21) 279-283

12/18/07