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Helen Diller Family Compr Cancer Ctr
OSAMU TETSU, MD, PHD

Assistant Adjunct Professor, Dept. of Pathology, UCSF

CONTACT

tetsu@cc.ucsf.edu
(415) 514-0870 (voice)
(415) 502-3179 (fax)

Box 0128, UCSF; San Francisco, CA 94143-0128

EDUCATION

Chiba University, School of Medicine, M.D., 1989, Medicine
Chiba University, Graduate School of Medicine, Ph.D., 1997, Surgery and Immunology
Chiba University Hospital, Department of Surgery, Residency, 1990-1997, General Surgery
University of California, San Francisco, Postdoc, 1997-2002, Cancer Biology

PROFESSIONAL EXPERIENCE

1990-1997

Resident, Department of Surgery, Chiba University Hospital

1997-1999

Visiting Postdoctoral Fellow, Dr. Frank McCormick Lab, Cancer Research Institute, University of California, San Francisco

1999-2002

Assistant Research Biochemist, Dr. Frank McCormick Lab, Cancer Research Institute, University of California, San Francisco

2002-2005

Assistant Adjunct Professor, Cancer Research Institute and Department of Surgery, University of California, San Francisco

2005-present

Assistant Adjunct Professor, Department of Pathology, University of California, San Francisco

HONORS & AWARDS

1990

Chiba University Hospital, 6th Isono Prize (1st place) for the Best Resident's Presentation

1993-1997

The Japan Scholarship Foundation, Graduate School Student Fellowship

2000

The Uehara Memorial Foundation, Research Fellowship Award

2003

American Cancer Society, Institutional Individual Research Award

2004

UCSF Research-Evaluation and Allocation Committee (REAC), New Junior Faculty Award

2004

Chiba University School of Medicine Alumni Association, Outstanding Academic Achievement Award

2004

The Concern Foundation, Young Investigator Award

2005

The V Foundation for Cancer Research, V Scholar Award

SELECTED PUBLICATIONS

Furukawa H, Hara T, Taniguchi T, Tetsu O. A case of spontaneous intramural hematoma of the esophagus. Gastroenterol Jpn. 1993;28:81-7.

Tetsu O, Kanno R, Isono K, Taniguchi M, Kanno M. Cloning and characterization of two transcripts generated from the mel-13 gene positioned adjacent to the mammalian Polycomb group-related gene mel-18. Biochim Biophys Acta. 1996;1305:109-12.

Akasaka T, Tsuji K, Kawahira H, Kanno M, Harigaya K, Hu L, Ebihara Y, Nakahata T, Tetsu O, Taniguchi M, Koseki H. The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors. Immunity. 1997;7:135-46.

Kenmochi T, Asano T, Nakagori T, Kaneko K, Nakajima K, Tetsu O, Jingu K, Iwashita C, Kainuma O, Tokoro Y, Sugamoto Y, Sakamoto K, Hatakeyama E, Yamada K, Isono K. Successful gene transfer into murine pancreatic islets using polyamine transfection reagents. Transplant Proc. 1998;30:470-2.

Hasegawa M, Tetsu O, Kanno R, Inoue H, Ishihara H, Kamiyasu M, Taniguchi M, Kanno M. Mammalian Polycomb group genes are categorized as a new type of early response gene induced by B-cell receptor cross-linking. Mol Immunol. 1998;35:559-63.

Tetsu O, Ishihara H, Kanno R, Kamiyasu M, Inoue H, Tokuhisa T, Taniguchi M, Kanno M. mel-18 negatively regulates cell cycle progression upon B cell antigen receptor stimulation through a cascade leading to c-myc/cdc25. Immunity. 1998;9:439-48.

Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 1999;398:422-6.

Wakita K, Tetsu O, McCormick F. A mammalian two-hybrid system for adenomatous polyposis coli-mutated colon cancer therapeutics. Cancer Res. 2001;61:854-8.

Wakita K, McCormick F, Tetsu O. Method for screening ecdysone-inducible stable cell lines. Biotechniques. 2001;31:414-8.

Tetsu O, McCormick F. Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell. 2003;3:233-45.

Rodriguez-Viciana P*, Tetsu O*, Tidyman WE, Estep AL, Conger BA, Santa Cruz M, McCormick F, Rauen KA. Germline Mutations in Genes within the MAPK Pathway Cause Cardio-facio-cutaneous Syndrome. Science. 2006 Jan 26; [Epub ahead of print] (*co-first author)

2/1/06

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