Associate Professor, Cancer Research Institute and Biochemistry & Biophysics, UCSF
Member, UCSF Biomedical Sciences Graduate Program (BMS) and Herbert Boyer Program in Biological Sciences (PIBS)
Co-Leader, DNA Repair and Radiation Biology Program, UCSF Helen Diller Family Comprehensive Cancer Center
| CONTACT | |
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toczyski@cc.ucsf.edu Box 0128, UCSF; San Francisco, CA 94143-0128 |
additional websites: |
| EDUCATION | |
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State University of New York/Buffalo, B.S., 1987, Biology
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| PROFESSIONAL EXPERIENCE | |
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1984-1986 |
State University New York - Buffalo, Undergrad Research |
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1987-1992 |
Yale University, Graduate Student |
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1991-1992 |
Yale University, Bass Writing Teacher |
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1993-1998 |
University of Washington/FHCRC, Postdoctoral Associate |
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1998-2005 |
UCSF Biochemistry & Biophysics/CRI, Assistant Professor |
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2005-present |
UCSF Biochemistry & Biophysics/CRI, Associate Professor |
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2006-present |
Co Leader, Comprehensive Cancer Center Program in DNA repair, UCSF |
| HONORS & AWARDS | |
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Summa Cum Laude | |
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Phi Beta Kappa | |
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1984-86 |
University Honors Scholar |
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1993-1996 |
Jane Coffin Childs Fellow |
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2003-2009 |
Leukemia and Lymphoma Society Scholar |
| SELECTED PUBLICATIONS | |
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Paulovich, A., Toczyski, D.P., and Hartwell, L.H. (1997) "When checkpoints fail". Cell 88: 315-321. | |
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Toczyski,D.P., Galgoczy, D.J., and Hartwell, L.H. (1997) "CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint". Cell 90: 1097-1106. | |
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Hartwell, L., Paulovich, A., and Toczyski, D. P. (1997). "The DNA damage Checkpoint" in Genomic instability and immortality in Cancer pg. 149-157. Plenum Press, NY | |
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Galgoczy, D.J., and Toczyski, D.P. (2001) "Checkpoint adaptation precedes spontaneous and DNA damage-induced genomic instability in S. cerevisiae" MCB 21: 1710-1718 | |
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Melo, J., Cohen, J. and Toczyski, D.P. (2001) "Two checkpoint complexes are independently recruited to sites of DNA damage in vivo" Genes and Development 15: 2809-2821 | |
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Melo, J. and Toczyski, D. P. (2002) "The DNA damage checkpoint response" Current Opinions in Cell Biology 14: 237-245 | |
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Thornton B.R., and Toczyski D.P. (2003) "Securin and B-cyclin/CDK are the only essential targets of the APC." Nature Cell Biology 5(12): 1090-4. | |
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Thornton B.R., and Toczyski D.P. (2003) "Precise destruction: an emerging picture of the APC." Genes & Development 20:3069-3078. |
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Thornton, B.R., Chen, K.C., Cross, F.R., Tyson, J.J., and Toczyski, D.P. (2004) "Cycling without the cyclosome: Modeling a yeast strain lacking the APC." The Cell Cycle. 3(5): 629-33 | |
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Kaye, J., Melo, J., Cheung, S.K., Vaze, M.B., Haber, J. and Toczyski, D. P. (2004) "DNA breaks promote genomic instability by impeding proper chromosome segregation" Current Biology14(23):2096-2106. | |
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Garber, P.M., Vidanes, G.M., Toczyski, D.P. (2005) Damage in transition. Trends Biochem Sci. 30(2): 63-6. | |
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Vidanes, G.M., Bonilla, C.Y., Toczyski, D.P. (2005) Complicated tails: histone modifications and the DNA damage response. Cell. Jul 1;121(7):973-6. | |
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Toczyski, D.P. (2006) "Methods for studying adaptation to the DNA damage checkpoint in yeast." Methods in Enzymology. Methods Enzymol. 2006;409:150-65. | |
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Thornton, B.R., Ng, T.M., Matyskiela, M.E., Carroll, C.W. Morgan, D.O., and Toczyski, D.P. (2006) "An architectural map of the anaphase promoting complex." Genes & Development 20(4):449-60. | |
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Maas, N. Miller, K. DeFazio, L. and Toczyski, D.P. (2006) "Cell cycle and checkpoint regulation of H3 K56 Acetylation by Hst3 and Hst4." Mol Cell. 2006 Jul 7;23(1):109-19. | |
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1/29/07 |
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