Sharof M. Tugizov, DVM, PhD, DSc

Institute of Agriculture, School of Veterinary Medicine, Samarkand, Uzbekistan (former Soviet Union), DVM 1981, Veterinary Medicine
Institute of Experimental Veterinary Medicine, Moscow, Russia, PhD, 1985, Virology, Cell Biology
Ivanosky Institute of Virology, Russian Academy of Medical Sciences, Moscow, Russia, DSc, 1996, Medical Virology Infectious Disease

• 1985-88 Junior Research Scientist, Dept. of Virus Physiology, Ivanovsky Institute of Virology, Academy of Medical Sciences, Moscow, USSR
• 1988-91 Senior Research Scientist, Dept. of Molecular Biology, Ivanovsky Institute of Virology, Academy of Medical Sciences, Moscow, USSR
• 1991-94 Visiting Scientist, Department of Stomatology, School of Dentistry, University of California, San Francisco, California
• 1994-99 Researcher in Virology and Molecular Biology, Department of Stomatology, School of Dentistry, University of California, San Francisco, California
• 1999-2005 Assistant Adjunct Professor, Department of Medicine, School of Medicine, University of California, San Francisco, California
• 2005-current Associate Professor (adj), Department of Medicine, School of Medicine, University of California, San Francisco, California

• Filatov, F.P., Tugizov, S.M., Savchencova, I.P., Kumarev, V.P., Belicov, A.S., Kadoshnikov, U.L., Kush, A.A., and Urevaev, L.V. Recombinant surface protein of hepatitis B virus that expose immunodominant membrane protein of HIV. Dokladi Akademiya Nauk of Russian Federation (Proc. of Nat. Acad. Sci., Russian Federation), 1:327, 1992.
• Shumay, E.P., Vorobiev, S.M., Makarova, N.E., Tugizov, S.M, Zverev, V.V., and Kush, A.A., Monoclonal antibodies to HIV p24 for the enzyme immunoassay detection of HIV antigen. Voprosi virusologiya (Questions in Virology), 5/6:229-232, 1992.
• Tugizov, S.M., Savchencova, I.P., Grabovskaya, I.L., and Kush, A.A., Changes of hepatitis B virus gene expression in human hepatocarcinoma cell line PLC-PRF-5 in the progress of drug-resistant phenotype formation. Voprosi virusologiya (Questions in Virology), 5/6:238-241, 1992.
• Filatov, F.P., Tugizov, S.M., and Kunarev, V.P., Designing exposition vectors on the basis of HBsAg. Sov. Med. Rev. E: Virology Reviews, 5:27-42, 1992. Printed in the United Kingdom, London.
• Grabovskaya, I.L., Tugizov, S.M., Glukhova, L.A., and Kush, A.A. Cytogenetic analysis of human hepatocarcinoma cell line PLC-PRF-5 and its mutant clones with different degrees of cell differentiation. Cancer Genetics and Cytogenetics, 65:145-151, 1993.
• Tugizov, S.M., Savchenkova, I.P., Grabovskaya, I.L., Makarova, N.E., Eraizrer, T.L., Revazova, E.S., and Kush, A.A., Changes in expression of surface and core antigens of hepatitis B in different mutant clones of hepatoma PLC-PRF-5 cells. Virus Research, 30:189-203, 1993.
• Navarro, D., P. Paz, S. Tugizov, K. Topp, J. La Vail, and L. Pereira. Glycoprotein B of human cytomegalovirus promotes virion penetration into cells, transmission of infection from cell to cell, and fusion of infected cells. Virology, 197:143-158, 1993.
• Tugizov, S., D. Navarro, P. Paz, Y. Wang, I. Qadri, and L. Pereira. Function of human cytomegalovirus glycoprotein B: Syncytium formation in cells constitutively expressing gB is blocked by virus-neutralizing antibodies. Virology, 201:263-276, 1994.
• Tugizov, S., Y. Wang, I. Qadri, D. Navarro, E. Maidji, and L Pereira. Mutated forms of human cytomegalovirus glycoprotein B are impaired in inducing syncytium formation. Virology, 209:580-591, 1995.
• Ramakrishnan, M., S. Tugizov, L. Pereira, and S. Lee. Conformation-defective herpes simplex virus 1 glycoprotein B activates the promoter of grp94 gene that codes for the 94-kD stress protein in the endoplasmic reticulum. Cell Biology and DNA, 14: 373-384, 1995.
• Pereira, L., E. Maidji, S. Tugizov, and T. Jones. Deletion mutants in human cytomegalovirus glycoprotein US9 are impaired in cell-cell transmission and in altering tight junctions of polarized human retinal pigment epithelial cells. Scand. J. of Infect. Dis., 99: 82-87, 1995.
• Tugizov, S., E. Maidji, and L. Pereira. Role of apical and basolateral membranes in replication of human cytomegalovirus in polarized retinal pigment epithelial cells. J. of General Virology, 77:61-74, 1996.
• Maidji, M., S. Tugizov, T. Jones, Z. Zheng, and L. Pereira. Accessory human cytomegalovirus glycoprotein US9 in the unique short component of the viral genome promotes cell-to-cell transmission of virus in polarized epithelial cells. J. Virology, 70:8402-8410, 1996.
• Zheng, Z., E. Maidji, S. Tugizov, and L. Pereira. Mutations in the carboxy-terminal hydrophobic sequence of human cytomegalovirus glycoprotein B alter transport and protein chaperone binding. J. Virology, 70:8029-8040, 1996.
• Navarro, D., E. Lennette, S. Tugizov, and L. Pereira. Humoral immune response to functional regions of human cytomegalovirus glycoprotein B. J. Med. Virol., 52:451-459, 1997.
• Tugizov, S., E. Maidji, J. Xiao and L. Pereira. Human cytomegalovirus glycoprotein B contains determinants for apical transport in polarized epithelial cells. J. Virol., 72:7374-7386, 1998.
• Navarro, D., Lenette, E., Tugizov, S., and Pereira, L., Humoral immune response to functional regions of human cytomegalovirus glycoprotein B. J. Med. Virol., 52:451-459, 1997.
• Maidji, E., Tugizov, S., Abenes, G., Jones, T., and Pereira, L., A novel human cytomegalovirus glycoprotein, gpUS9, which promotes cell-to-cell spread in polarized epithelial cells, colocalizes with cytoskletal proteins E cadherin and F-actin. J. Virol., 72:5717-5727, 1998.
• Tugizov, S., Maidji, E., Xiao, J., Z., Zheng and Pereira, L., Human cytomegalovirus glycoprotein B contains autonomous determinants for vectorial targeting to apical membranes of polarized cells. J. Virol., 72:7374-7386, 1998.
• Tugizov, S., Maidji, E., Xiao, J., and Perera., An acidic cluster in the cytosolic domain of human cytomegalovirus glycoprotein B functions as a signal for internalization of CMV gB. J. Virol., 73;8677-8688, 1999.
• D'konov, L.P., Sitkov, V.I., Galnbek, T.V., Kulikova, I.L., Zaerko, B.E., Kushch, A.A., Tugizov, S.M. et al, Biology of animal cells. Textbook, Published by Russian Academy of Science. Publisher: Kompaniya sputnik, p 400, Moscow, 2000.
• Berline J., Tugizov, S., and Palefsky J., Entry of Epstein Barr virus into polarized oral epithelial cells. Oral Diseases, 8:188-189, 2002.
• Tugizov, S., Berline, J., and Palefsky, J., Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells. Nature Medicine, 9:307-314, 2003.
• Tugizov, S., Berline, J., Herrera, R., Penaranda, M., Nakagawa, M., and Palefsky, J., Inhibition of HPV16 E7 phosphorylation by the S100 MRP-8/14 protein complex. J. Virol, 79:1099-1112, 2005.
• Jianqiao Xiao, Joel Palefsky, Rossana Herrera and Sharof Tugizov. Characterization of the Epstein-Barr virus Glycoprotein BMRF-2, Virology, 359:382-396, 2007
• Sharof Tugizov, Rossana Herrera, Piri Veluppillai, John Greenspan, Deborah Greenspan and Joel M. Palefsky, EBV-infected monocytes facilitate dissemination of EBV within the oral mucosal epithelium. 2007, J. Virol, 81:5484-5496, 2007