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SCOTT RUSSEL VANDENBERG, MD, PHD

Professor in Residence, Departments of Pathology and Neurologic Surgery, UCSF

CONTACT

vandenb@itsa.ucsf.edu
(415) 502-7796 (voice)
(415) 476-7963 (fax)

Box 0511, UCSF; San Francisco, CA 94143-0511

EDUCATION
Duke University, BS, 1968-1972, Zoology Stanford University School of Medicine, M.D., Ph.D., 1972-1979, Medicine/Neurosciences University of Colorado, Intern, 1979-1980, Pathology Stanford University School of Medicine, Postdoctorate, 1980-1982, Neurochemistry/Neuropath University of Virginia, Resident, 1982-1984, Pathology/Neuropathology
PROFESSIONAL EXPERIENCE
1984-1990	Assistant Professor of Pathology, University of Virginia School of Medicine
1984-2003	Faculty of the Neurosciences Graduate Program, University of Virginia School of Medicine
1990-2003	Director of Neuropathology, Neuropathology Training Program; Director, Department of Pathology, University of Virginia School of Medicine
1990-1993	Associate Professor of Pathology (with tenure),*University of Virginia School of Medicine
1994-2003	Professor of Pathology and Neurological Surgery, University of Virginia School of Medicine
1994-2003	Division Head, Neuropathology, University of Virginia School of Medicine
1998-2003	Medical Director of Neuropathology Lab Services, Director of the Special Tissues Laboratory, University of Virginia School of Medicine
1998-2003	John T. and Louise Nerancy Professor of Neurosciences,University of Virginia School of Medicine
2003-present	Professor in Residence, Departments of Pathology and Neurologic Surgery, University of California, San Francisco
HONORS & AWARDS
1976-1979	Scholar of the Insurance Medical Scientist Fund
1984	Weil Award for the Best Paper in Experimental Neuropathology, AANP
1985	Honorable mention for Moore Award for Best Paper in Clinical Neuropathology, AANP
	Charter Member, Diagnostic Slide Session, AANP
SELECTED PUBLICATIONS
(in chronological order from 69 peer-reviewed publications)
Wolf, B.B., Lopes, M.B.S., VandenBerg, S.R. and Gonias, S.L. (1992) Characterization and Immunohistochemical Localization of ±-Macroglobulin Receptor (Low Density Lipoprotein-Receptor Related Protein) in Human Brain. Am. J. Pathol. 141:37-42.
Gonzalez-Fernandez, F., Lopes, M.B.S., Garcia-Fernandez, J.M., Foster, R.G., De Grip, W.J., Newman, S. and VandenBerg, S.R. (1992) Expression of developmentally-defined retinal phenotypes in the histogenesis of retinoblastoma. Amer. J. Pathol. 141:363-375.
Geanacopoulos, M., Turner, J., Bowling, K.E., VandenBerg, S.R. and Gear, A.R.L. (1993) The role of protein kinase C in the initial events of platelet activation by thrombin assessed with a selective inhibitor. Throm. Res. 69:113 124.
Lopes, M.B.S., Gonzalez-Fernandez, F., Scheithauer, B.W. and VandenBerg, S.R. (1993) Differential Expression of Retinal Proteins in a Pineal Parenchymal Tumor J. Neuropathol. Exp. Neurol. 52:516-524.
Turner, J., Redpath, G.T., Humphries, J.E., Gonias, S.L. and VandenBerg, S.R. (1994) Plasmin Selectively Modulates the Thrombin Evoked Calcium Response in C6 Glioma Cells. Biochemical Journal 297:175-179.
Lopes, M.B.S., Bogaev, C.A., Gonias, S.L. and VandenBerg, S.R. (1994) Expression of alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells. FEBS Lett. 338:301-305.
Eberhard, D.A., Brown, M.D., and VandenBerg, S.R. (1994) Alterations of annexin expression in pathologic neuronal and glial reactions: Immunohistochemical localization of annexins I, II (p36 and p11 subunits), IV, and VI in the human hippocampus. Amer. J. Pathol. 145:640-649.
Hirose, T., Scheithauer, B.S., Lopes, M.B., and VandenBerg, S.R. (1994) Dysembryoplastic neuroepithelial tumor (DNT): An immunohistochemical and ultrastructural study. Neuropathol. Exp. Neurol. 53:184-195.
Hussaini, I.M., La Marre, J., Lysiak, J.L., Karns, L.R., VandenBerg, S.R., and Gonias, S.L. (1996) Transcriptional regulation of low density lipoprotein receptor-related protein by interferon-³ and the antagonistic activity of transforming growth factor-² in the RAW 264.7 macrophage-like cell line. J. Leukocyte Biol. 59:733-739.
Brown, M.D., Banker, G.A., Hussaini, I.M., Gonias, S.L., and VandenBerg, S.R. (1997) Low density lipoprotein receptor-related protein is expressed early and becomes restricted to a somatodendritic domain during neuronal differentiation in culture. Brain Research 747: 313-317.
Eberhard, D.A., and VandenBerg, S.R. (1998) Annexins I and II Bind to Lipid A: A Possible Role in the Inhibition of Endotoxins. Biochem. J. 330:67-72.
Mandell, J.W., Hussaini, I.M., Zecevic, M., Weber, M.J., VandenBerg, S.R. (1998) In Situ Visualization of Intratumoral Growth Factor Signaling: Immunohistochemical localization of activated ERK/MAP kinase in glial neoplasms. Am. J. Pathol. 153: 1411-1423.
Hussaini, I.M., Brown, M.D., Karns. L.R., Carpenter, J., Redpath, G.T., Gonias, S.L., VandenBerg, S.R. (1999) Epidermal Growth Factor Differentially Regulates Low-Density Lipoprotein Receptor-Related Protein Gene Expression in Neoplastic and Fetal Human Astrocytes. Glia 25:71-84, 1999.
Hirano, H., Lopes, M.B.S., Carpenter, J., Laws, E.R. Jr., Asakura, T., Goto, M., Karns, L.R., VandenBerg, S.R. (1999) The IGF-I Content and Pattern of Expression Correlates with Histopathologic Grade in Diffusely Infiltrating Astrocytomas. Neuro-Oncology 1:109-119.
Hussaini, I.M., Brown, M.D., Weaver, A.M., Carpenter, J., Karns, L.R., VandenBerg, S.R., Gonias, S.L. (1999) Stable antisense RNA expression neutralizes the activity of low density lipoprotein receptor-related protein and promotes urokinase accumulation in the medium of an astrocytic tumor cell line. Antisense and Nucleic Acid Drug Development 9:183-190.
Mandell, J.M., VandenBerg, S.R. (1999) ERP/MAP Kinase is chronically activated in human reactive astrocytes. NeuroReport 10:3567-3572.
Hussaini,I.M., Karns, L.R., Vinton, G., Carpenter, J., Redpath, G.T., Sando,J.J., VandenBerg, S.R. (2000) Phorbol 12-Myristate -13-Acetate Induces Protein Kinase C eta-Specific Cell Proliferative Response in Astrocytic Tumor Cells. J. Biol. Chem. 275:22348-22354.
Mandell JW , Gocan NC, and VandenBerg SR. (2001) Mechanical Trauma Induces Rapid Astroglial Activation of ERK/MAP Kinase: Evidence for a Paracrine Signal. Glia 34:283-395.
Eberhard, D,A., Karns, L.R., VandenBerg, S.R., and Creutz., C.E. (2001) Control of the Nuclear-cytoplasmic Partitioning of Annexin II by a Nuclear Export Signal and by p11 Binding. J. Cell Sci. 114:3155-3166.
Hussaini, I.M., Sando, J.J., Shaffrey, M. and VandenBerg, S. (2002) Protein Kinase C-eta regulates resistance to irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation. Neuro-Onocology. 4:9-21.
Giannini, C., Scheithauer, B.W., Lopes M.B., Hirose, T., Kros, J.M., VandenBerg, S.R. (2002) Immunophenotype of pleomorphic xanthoastrocytoma. Am. J. Surg. Path. 26:479-85.
12/15/04

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