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Helen Diller Family Compr Cancer Ctr
RONG WANG, PHD

Mildred V. Strouss Endowed Chair in Vascular Surgery, UCSF
Director, Laboratory for Accelerated Vascular Research, UCSF
Member, UCSF Biomedical Sciences Graduate Program (BMS) and Herbert Boyer Program in Biological Sciences (PIBS) and Affiliate Member, UCB/UCSF Graduate Group in Bioengineering

CONTACT

rong.wang@ucsfmedctr.org
(415) 476-6855 (voice)
(415) 564-5698 (fax)

Box 0507, UCSF; San Francisco, CA 94143-0507

EDUCATION

Sichuan University, Chendu, China, B.Sc., 1980-84, Biology
Graduate School of Chinese Science and Technology University, Institute of Genetics, Academia Sinica, Beijing, China, M.Sc. candidate, 1984-88, Genetics
University of North Carolina at Chapel Hill, Ph.D., 1988-93, Biology (Angiogenesis)
University of California, San Francisco, Postdoctoral Fellow, 1994-2001, Cancer Biology

PROFESSIONAL EXPERIENCE

1988-1993

Graduate Research Assistant, Dr. Victoria L. Bautch, Department of Biology, University of North Carolina at Chapel Hill

1994-2001

Postdoctoral Fellow, J. Michael Bishop, G.W. Hooper Laboratory, UCSF

2001-2007

Assistant Professor, Surgery and Anatomy, UCSF

2001-present

Director, Laboratory for Accelerated Vascular Research, UCSF

2006-present

Mildred V. Strouss Endowed Chair in Vascular Surgery

2007-2008

Associate Professor, Anatomy, UCSF

2007-present

Associate Professor, Surgery, UCSF

HONORS & AWARDS

1994-97

Leukemia Society of America, Postdoctoral Fellowship

1997-99

American Heart Association, Postdoctoral Fellowship

2003-2005

Pfizer Atorvastatin Research Award

SELECTED PUBLICATIONS

Dubois, NA, LC Kolpack, R Wang, RG Azizkhan and VL Bautch. Isolation and characterization of an established endothelial cell line from transgenic mouse hemangiomas. Exp Cell Res, 1991 196(2): 302-13.

Wang, R and VL Bautch. The polyomavirus early region gene in transgenic mice causes vascular and bone tumors. J Virol, 1991 65(10): 5174-83.

Wang, R, R Clark and VL Bautch. Embryonic stem cell-derived cystic embryoid bodies form vascular channels: an in vitro model of blood vessel development. Development, 1992 114(2): 303-16.

Wang, R, GP Siegal, DL Scott and VL Bautch. Developmental analysis of bone tumors in polyomavirus transgenic mice. Lab Invest, 1994 70(1): 86-94.

Wang, R, R Kobayashi and JM Bishop. Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor. Proc Natl Acad Sci U S A, 1996 93(16): 8425-30.

Wang, R, LD Ferrell, S Faouzi, JJ Maher and JM Bishop. Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice. J Cell Biol, 2001 153(5): 1023-34.

Chang, DS, H Su, GL Tang, LS Brevetti, R Sarkar, R Wang, YW Kan and LM Messina. Adeno-associated viral vector-mediated gene transfer of VEGF normalizes skeletal muscle oxygen tension and induces arteriogenesis in ischemic rat hindlimb. Mol Ther, 2003 7(1): 44-51.

Tang, G, DN Charo, R Wang, IF Charo and L Messina. CCR2-/- knockout mice revascularize normally in response to severe hindlimb ischemia. J Vasc Surg, 2004 40(4): 786-95.

Tang, GL, DS Chang, R Sarkar, R Wang and LM Messina. The effect of gradual or acute arterial occlusion on skeletal muscle blood flow, arteriogenesis, and inflammation in rat hindlimb ischemia. J Vasc Surg, 2005 41(2): 312-20.

Yan, J, GL Tang, R Wang and LM Messina. Optimization of Adenovirus-mediated endothelial nitric oxide synthase delivery in hindlimb ischemia. Gene Therapy, 2005 12(22):1640-50.

Carpenter, B, Y Lin, S Stoll, RL Raffai, R McCuskey and R Wang. VEGF is crucial for the hepatic vascular development required for lipoprotein uptake. Development, 2005 132(14): 3293-303.

Carlson, TR, Y Yan, X Wu, MT Lam, GL Tang, LJ Beverly, LM Messina, AJ Capobianco, Z Werb and R Wang. Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice. Proc Natl Acad Sci U S A, 2005 102(28): 9884-9.

Proctor, JM, K Zang, D Wang, R Wang and LF Reichardt. Vascular Development of the Brain Requires beta8 Integrin Expression in the Neuroepithelium. J Neurosci, 2005 25(43): 9940-8.

Braren, R, H Hu, YH Kim, H Beggs, LF Reichardt and R Wang. Endothelial FAK is essential for vascular network stability by regulating lamellipodial formation and cell survival. J Cell Biol, 2006 176(1): 151-162.

Tward, AD, KD Jones, S Yant, ST Cheung, ST Fan, X Chen, MA Kay, R Wang, JM Bishop. Distinct pathways of genomic progression to benign and malignant tumors of the liver. Proc Natl Acad Sci U S A, 2007 104(37): 14771-14776.

Carlson, TR, H Hu, R Braren, YH Kim, and RA Wang. Cell-autonomous requirement for β1 integrin in endothelial cell adhesion, migration, and survival during angiogenesis in mice. Development, 2008 135(12):2193-202.

He, C, H Hu, R Braren, S-Y Fong, A Trumpp, TR Carlson, and RA Wang. c-myc in the hematopoetic lineage is crucial for its angiogenic function in the mouse embryo. Development, 2008 135(14):2467-77.

Dubois, NC, C Adolphe, A Ehninger, RA Wang, EJ Robertson, and A Trumpp. Placental rescue reveals a sole requirement for C-Myc in embryonic erythroblast survival and hematopoietic stem cell function. Development, 2008 135(14):2455-65.

Murphy, PA, MTY Lam, X Wu, TN Kim, SM Vartanian, AW Bollen, TR Carlson, and RA Wang. Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice. Proc Natl Acad Sci U S A, 2008 105(31):10901-10906.

7/31/08

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