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Helen Diller Family Compr Cancer Ctr
MARGARET R. WRENSCH, PHD

Stanley D. Lewis and Virginia S. Lewis Endowed Chair in Brain Tumor Research, UCSF
Member, UCSF Helen Diller Family Comprehensive Cancer Center

CONTACT

margaret.wrensch@ucsf.edu
(415) 476-1979 (voice)
(415) 502-1787 (fax)

Box 1215, UCSF, San Francisco, CA 94143-1215

EDUCATION

Ohio State University, Columbus, OH, B.Sc., 1971, Genetics
Ohio State University, Columbus, OH, M.Sc., 1973, Population Genetics
University of California, Berkeley, CA, M.P.H., 1977, Epidemiology
University of California, Berkeley, CA, Ph.D., 1983, Epidemiology

PROFESSIONAL EXPERIENCE

1985-1988

Epidemiologist, California Department of Health Services, Berkeley

1986-present

Assistant, Associate, and Full Professor (Adjunct 1986-6/2002; In Residence 7/2002-present), Dept. of Epidemiology and Biostatistics, University of California, San Francisco

1993-1994

Chief, Division of Epidemiology at Parnassus, University of California, San Francisco

2001-present

Adjunct Investigator, Kaiser Permanente, Division of Research, Oakland

2001

Interim Head, Cancer Epidemiology Division, University of California, San Francisco

2004-present

Co-Director Neuroepidemiology Division

2005

Stanley D. Lewis and Virginia S. Lewis Endowed Chair in Brain Tumor Research

SELECTED PUBLICATIONS

Lee M, Wrensch M, Miike R. Dietary and tobacco risk factors for adult onset glioma in the San Francisco Bay Area (California USA). Cancer, Causes & Control 1997;8:13-24.

Wrensch M, Lee M, Miike R, et al. Familial and personal medical history of cancer and nervous system conditions among adults with glioma and controls. Am J Epidemiol 1997;145:581-93.

Wrensch M, Weinberg A, Wiencke J, Masters H, Miike R, Barger G, Lee M. Does prior infection with varicella zoster virus influence risk of adult glioma? Am J Epidemiol 1997;145:594-7.

Aldape K, Simmons M, Davis R, Miike R, Wiencke J, Barger G, Lee M, Chen P, Wrensch M. Discrepancies in diagnoses of neuroepithelial neoplasms: The San Francisco Bay Area Adult Glioma Study. Cancer 2000;88:2342-9.

Lee, MM; Lin, SS; Wrensch, MR; Adler, SR; Eisenberg, D. Alternative therapies used by women with breast cancer in four ethnic populations. JNCI 2000; 92:42-7.

Chen P, Wiencke J, Aldape K, Kesler-Diaz A, Miike R, Kelsey K, Lee M, Liu J, Wrensch M. Association of an ERCC1 polymorphism with adult onset glioma. Cancer Epidemiol, Biomarkers,& Prev, 2000;9:843-7.

Wiencke J, Kelsey K, Zuo Z, Weinberg A, Wrensch M. Genetic resistance factor for HIV-1 and immune response to varicella-zoster. Lancet, 2001; 357 (9253):360-1.

Chen P, Aldape K, Wiencke J, Kelsey K, Miike R, Davis R, Liu J, Diaz A, Takahashi M, and Wrensch M. Ethnicity delineates different genetic pathways in malignant glioma. Cancer Research 2001; 61(10):3949-3954

Wrensch M, Weinberg A, Wiencke J, Miike R, Barger G, Kelsey K. Prevalence of antibodies to four herpesviruses among adults with glioma and controls. American Journal of Epidemiology 2001;154(2):161-65.

Wrensch M, Petrakis NL, Miike R, King EB, Chew K, Neuhaus, Lee MM, Rhys M. Breast cancer risk in women with abnormal cytology in nipple aspirates of breast fluid. JNCI 2001;93:1791-8.

Tedeschi-Blok N, Schwartzbaum J, Lee M, Miike R, Wrensch M. Dietary calcium and adult glioma. Nutrition and Cancer 2001;39:196-203.

Wiemels JL, Wiencke JK, Sison JD, Miike R, McMillan A, Wrensch MR. History of allergies among adults with glioma and controls. Int J Cancer 2002;98(4):609-15.

Clarke CA, Glaser SL, West DW, Ereman RR, Erdman CA, Barlow JM, Wrensch MR. Rapidly increasing incidence of breast cancer in an affluent population: Marin Count, California, USA, 1990-99. Breast Cancer Research 2002;4:R13

Lee MM, Chang JS, Jacobs B, Wrensch MR. Complementary and alternative medicine use among men with prostate cancer in 4 ethnic populations. American Journal of Public Health 2002;92:1601-9.

Wrensch M, Minn AY, Chew T, Bondy M, Berger M. Epidemiology of primary brain tumors: Current concepts and review of the literature. Neuro-oncology 2002; 4(4):278-299.

Cabral DN, Napoles-Springer AM, Miike R, McMillan A, Sison J, Wrensch MR, Perez-Stable EJ, Wiencke JK;San Francisco Bay Area Lung Cancer Study. Population- and community-based recruitment of African Americans and Latinos:the San Francisco Bay Area Lung Cancer Study. Am J Epidemiol. 2003 Aug 1;158(3):272-9.

Krishnan G, Felini M, Carozza SE, Miike R, Chew T, Wrensch M. Occupation and Adult Gliomas in the San Francisco Bay Area. J Occup Environ Med. 2003 June;45(6):639-47.

Aldape KD, Okcu MF, Bondy M, Wrensch M. Molecular epidemiology of glioblastoma. The Cancer Journal, 2003 Mar-Apr;9(2):99-106. Review.

Wrensch MR, Kelsey KT, Liu M, Miike R, Moghadassi M, Aldape K, McMillan A, Wiencke J. Constitutive polymorphisms in Glutathione S Transferase (GST) Mu (M1), Theta (T1), and Pi (P) in adults with glioma and controls. Cancer Epidemiology Biomarkers and Prevention, 2004 Mar;13(3):461-7.

Wiemels JL, Wiencke JK, Patoka J, Moghadassi M, Chew T, McMillan A, Miike R, Barger G, Wrensch M. Reduced immunoglobulin E and allergy among adults with glioma compared with controls. Cancer Res. 2004 Nov 15;64(22):8468-73.

Sivak-Sears NR, Schwartzbaum JA, Miike R, Moghadassi M, Wrensch M Case-control study of non-steroidal anti-inflammatory drug use and glioblastoma multiforme, Am J Epidemiol, 2004 Jun 15;159(12):1131-9.

Wrensch MR, Miike R, Sison JD, Kelsey KT, Liu M, McMillan A, Quesenberry C, Wiencke JK. CYP1A1 Variants and smoking related lung cancer in San Francisco Bay Area Latinos and African Americans. Int J Cancer, 2005 Jan 1;113(1):141-7.

Hwang ES, Chew T, Shiboski S, Farren G, Benz CC and Wrensch M. Risk factors for estrogen-receptor positive breast cancer, Archives of Surgery, Arch Surg 2005 Jan;140(1):58-62.

Wrensch, M.,, A. Weinberg, J. Wiencke, R. Miike, J. Sison, J. Wiemels, G. Barger, G. DeLorenze, K. Aldape, and K. Kelsey, History of chickenpox and shingles and prevalence of antibodies to varicella-zoster virus and three other herpes viruses among adults with glioma and controls. Am J Epidemiol., 2005. 161(10): p. 929-38.

Tang, J., W. Shao, M.T. Dorak, Y. Li, R. Miike, E. Lobashevsky, J.K. Wiencke, M. Wrensch, R.A. Kaslow, and C.S. Cobbs, Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme. Cancer Epidemiol Biomarkers Prev., 2005. 14(8): 2040-4.

Wiencke, J.K., K. Aldape, A. McMillan, J. Wiemels, M. Moghadassi, R. Miike, K.T. Kelsey, J. Patoka, J. Long, and M. Wrensch, Molecular features of adult glioma associated with patient race/ethnicity, age, and a polymorphism in O6-methylguanine-DNA-methyltransferase. Cancer Epidemiol Biomarkers Prev., 2005. 14(7): p. 1774-83.

Tice, J.A., R. Miike, K. Adduci, N.L. Petrakis, E. King, and M.R. Wrensch, Nipple aspirate fluid cytology and the Gail model for breast cancer risk assessment in a screening population. Cancer Epidemiol Biomarkers Prev., 2005. 14(2): p. 324-8.

Wrensch, M., K.T. Kelsey, M. Liu, R. Miike, M. Moghadassi, J.D. Sison, K. Aldape, A. McMillan, J. Wiemels, and J.K. Wiencke, ERCC1 and ERCC2 polymorphisms and adult glioma. Neuro-oncol., 2005. 7(4): p. 495-507.

Wrensch, M., J.L. Fisher, J.A. Schwartzbaum, M. Bondy, M. Berger, and K.D. Aldape, The molecular epidemiology of gliomas in adults. Neurosurg Focus., 2005. 19(5): p. E5.

Claus, E.B., M.L. Bondy, J.M. Schildkraut, J.L. Wiemels, M. Wrensch, and P.M. Black, Epidemiology of intracranial meningioma. Neurosurgery., 2005. 57(6): p. 1088-95; discussion 1088-95

Wrensch, M., T. Rice, R. Miike, A. McMillan, K. Lamborn, K. Aldape, and M. Prados, Diagnostic, treatment and demographic factors influencing survival in population based glioma patients in the San Francisco Bay Area. Neuro-oncology, 2006. 8(1): p. 12-26.

1/8/07

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