program
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Genetic Syndromes of the Ras/MAPK Pathway: From Bedside to Bench and Back Date: August 1-2, 2009 Location: Berkeley Marina, CA Doubletree Hotel | ||
>> Sunday, August 2, 2009 | ||
| Saturday, August 1, 2009 | ||
| 7:00-8:00 am | Registration and Breakfast | |
| 8:00-8:05 am | Welcoming Comments and Introduction: Katherine Rauen and Lisa Schoyer | |
| 8:05-8:25 am | Keynote Presentation #1: Advocates and Self-Advocates The Road Less Traveled: Our Journey on the Ras/MAPK Pathway | |
| 8:30-9:00 am | Keynote Presentation #2: Frank McCormick, PhD, FRS New Perspectives on an Ancient Pathway | |
| 9:00-10:15 am | Clinical Consequences of Molecular Alterations (10 mins. + 5 min. discussion) Moderator: Angela Lin, MD | |
| 9:00-9:15 am | Noonan Syndrome | Judith E. Allanson, MD |
| 9:15-9:30 am | Neurofibromatosis 1 and Legius Syndromes | David Stevenson, MD, PhD |
| 9:30-9:45 am | Costello Syndrome | Karen W. Gripp, MD |
| 9:45-10:00 am | Cardio-Facio-Cutaneous Syndrome | Giovanni Neri, MD |
| 10:00-10:15 am | Phenotypic Overlap: The Blurred Boundaries | John C. Carey, MD |
| 10:15-10:30 am | Break | |
| 10:30-12:10 pm | Biochemical Properties and Function of Altered Proteins: Perturbation of the Pathway (15 mins. + 5 min. discussion) Moderator: Eric Legius, MD | |
| 10:30-10:50 am | Neurofibromin and SPRED1 | Eric Legius, MD |
| 10:50-11:10 am | SHP2 | Marco Tartaglia, PhD |
| 11:10-11:30 am | KRAS and HRAS | Suzanne Schubbert, PhD |
| 11:30-11:50 am | SOS1 and CRAF | Amy E. Roberts, MD |
| 11:50-12:10 pm | BRAF and MEK1/2 | Katherine Rauen, MD, PhD |
| 12:10-1:15 pm | Lunch Break | |
| 1:15-3:15 pm | Pre-Clinical Modeling of Ras/MAPK Pathway Syndromes (15 mins. + 5 min. discussion) Moderator: Bruce D. Gelb, MD | |
| 1:15-1:35 pm | Pre-Clinical Modeling | Kevin Shannon, MD |
| 1:35-1:55 pm | Neurofibromatosis 1 Mouse Models | David H. Gutmann, MD, PhD |
| 1:55-2:15 pm | Overview of Raf Mouse Models | Martin McMahon, PhD |
| 2:15-2:35 pm | HRas G12V Mouse Model | Mariano Barbacid, PhD |
| 2:35-2:55 pm | HRas G12V Mouse Model | James Fagin, MD |
| 2:55-3:15 pm | K-Ras Mouse Model | Benjamin Yu, MD, PhD |
| 3:15 - 3:30 pm | Break | |
| 3:30-5:25 pm | Pre-Clinical Modeling (continued) Application of New Technologies (20 mins. + 5 min. discussion) Moderator: Yoko Aoki MD, PhD | |
| 3:30-3:50 pm | Noonan Syndrome Mouse Models | Ben G. Neel, MD |
| 3:50-4:10 pm | Noonan/LEOPARD Syndrome Models | Bruce D. Gelb, MD |
| 4:10-4:35 pm | Genetic Architecture | Allan Balmain, PhD, FRSE |
| 4:35-5:00 pm | Proteomics | Richard Drake, PhD |
| 5:00-5:25 pm | Phospho-Signaling | Garry P. Nolan, PhD |
| 6:00-7:30 pm | Banquet Dinner (Free, open to all registered symposium attendees) | |
| 7:30-9:30 pm | Dessert and Poster Session (Free, open to all symposium attendees and advocacy/family groups) | |