University of California San Francisco
Helen Diller Family Comprehensive Cancer Center

Funding & Research

Benioff Initiative for Prostate Cancer Research

Therapy for prostate cancer is not yet individualized based on the molecular drivers found within each individual’s cancers. This makes prostate cancer unlike other common cancers, such as breast, colon, and lung cancer. 

The difference highlights the critical need to understand the fundamental biology underlying aggressive prostate cancer, in order to radically improve outcomes. The UCSF Benioff Initiative looks to fund projects and core resources that aim to accelerate research in aggressive prostate cancer.

Funded Research Projects

The Benioff Initiative for Prostate Cancer Research is excited to announce the funded projects from our first RFA Cycle. Were received a total of 18 RFAs during this cycle and were able to provide funding to the top 6 scored proposals.  

RFA Funded Projects, February 2020 - January 2021:

Principal Investigators: Danica Fujimori, PhD & Lawrence Fong, MD
Project Title: Potentiating Prostate Cancer Immunogenicity through Epigenetic Modulation

Principal Investigators: Matthew Krummel, PhD & Vincent Chan, PhD
Co-Investigators: Felix Feng, MD & Eric Small, MD
Project Title: Investigating the Tumor Immune Microenvironment in Metastatic Prostate Cancer
Addition support for this project will be provided by the Bakar ImmunoX Initiative at UCSF.

Principal Investigator: David Quigley, PhD
Project Title: Investigating the evolution of targeted therapy resistance in advanced prostate tumors
This project will be cosponsored with the Center for BRCA Research.

Principal Investigators: Robert Blelloch, MD, PhD & James Fraser, PhD
Project Title: Enhancing the anti-tumor immune response in prostate cancer through the inhibition of exosomal PD-L1

Principal Investigators: Luke Gilbert, PhD & Eric Small, MD
Project Title: Systematic elucidation of WNT signaling in Prostate Cancer

Principal Investigators: Davide Ruggero, PhD & Hao Nguyen, MD, PhD
Project Title: Deciphering the role of the translational oncogenic program in prostate cancer


Funding Opportunities

Check back for funding opportunities soon.