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Scientific Accomplishments

Scientific Accomplishments

Selected highlights from the Program members are:

  • Demonstrated the critical role for microRNA in stem cell renewal (Blelloch lab, Nature)

  • Identified DNA as an allosteric ligand for nuclear receptors (Yamamoto Laboratory, Science)

  • First-in-man use of hyperpolarized 13C pyruvate for metabolic imaging (Kurhanewicz, NCI trials)

  • Established active surveillance as an option for men with low-risk prostate cancer (Carroll, multiple)

  • Program members led the first-in-man trials of Ipilimumab, Abiraterone, and Sipuleucel-T