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Symposium 2014

Targeting RAS Now for Future Cancer Therapy

June 19th (9:00 am - 5:30 pm)
June 20th (8:00 am - 12:45 pm)

Byers Auditorium, 600 16th Street, Mission Bay

The 2014 Helen Diller Family Comprehensive Cancer Center Symposium, “Targeting RAS Now for Future Cancer Therapy”, will be held Thursday, June 19th and Friday, June 20th, 2014 at the UCSF Mission Bay campus.

There will be five scientific sessions that will span the gamut of RAS biology and biochemistry in relation to normal and abnormal development and relevance to cancer initiation, progression and therapy. The scientific sessions will be open to academic and industry colleagues in the Bay Area. 

Agenda     Contact

Thursday, June 19th
8:30 AM Continental Breakfast
9:00 AM - 9:30 AM Welcome & Introduction
9:30 AM - 11:45 AM Session 1: Direct Attack on the Ras Protein

Kevan Shokat, PhD, Professor and Chair of Cellular and Molecular Pharmacology UC, San Francisco

Stephen Fesik, PhD, Professor of Biochemistry, Pharmacology, and Chemistry Vanderbilt-Ingram Cancer Center

Carla Mattos, PhD, Professor of Chemistry Northeastern University
11:45 AM - 12:45 PM Lunch
12:45 PM - 3:00 PM

Session 2: Disrupting Ras Signaling in the Membrane

James Fagin, MD,. Chief of Endocrinology Service Memorial Sloan-Kettering Cancer Center

Herbert Waldmann, PhD, Professor of Chemistry Max Planck Institute of Molecular Physiology

Dafna Bar-Sagi, PhD, Professor of Biochemistry and Molecular Pharmacology NYU Langone Medical Center

3:00 PM - 3:15 PM Break
3:15 PM - 5:30 PM Session 3: Targets Downstream of KRAS

Deborah Morrison, PhD, Chief, Laboratory of Cell Development and Signaling, NCI Center for Cancer Research

Julian Downward, PhD, Professor Cancer Research UK

Martin McMahon, PhD, Professor, Helen Diller Family Comprehensive Cancer Center University of California, San Francisco
5:45 PM Cocktail Reception
Friday, June 20th
7:30 AM Continental Breakfast
8:00 AM - 10:15 AM Session 4: Ras and NF1 in Human Cancer

Kevin Shannon, MD, Professor of Pediatrics, UCSF

Erica Jackson, PhD, Scientist, Genentech, Inc.

Eric Collisson, MD, Assistant Professor of Medicine, UCSF
10:15 AM - 10:30 AM Break
10:30 AM - 12:45 PM Session 5: Novel Properties of Ras

Xiaolin Nan, PhD, Assistant Professor of Biomedical Engineering, Oregon Health & Science University

Christin Burd, PhD, Assistant Professor of Molecular Genetics, Ohio State University

Frank McCormick, PhD, FRS, DSc (Hon), Professor Emeritus, Helen Diller Family Comprehensive Cancer Center, UCSF
12:45 PM Adjourn


Contact Jordan Brainerd at brainerdj@cc.ucsf.edu for more information.

Image: Structure of drug-bound KRAS. Image courtesy of Jonathan Ostem (Shokat Lab, UCSF)