• Home
  • Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D.

Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D.

Author List
Zheng Q, Zhang Z, Guiley KZ, Shokat KM
Publication
Nature chemical biology
Publication ID (Profile URL)
https://researcherprofiles.org/profile/488654650
Publication Year
2024
PubMed ID
38443470
Publication Title
Zheng Q, Zhang Z, Guiley KZ, Shokat KM. Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nat Chem Biol. 2024 09; 20(9):1114-1122.