Research Summary
Carolyn S. Calfee, MD MAS is Professor of Medicine and Anesthesia at the University of California, San Francisco, where she attends in the intensive care units. Her primary academic focus is the pathogenesis and treatment of the acute respiratory distress syndrome (ARDS). Current research projects include: (1) molecular subphenotypes of ARDS and precision medicine in critical care; (2) the role of environmental exposures including smoking, air pollution, and novel tobacco products in susceptibility to lung injury; and (3) novel treatments for ARDS. During the COVID-19 pandemic, she has been the UCSF clinical lead and steering committee member for the NIAID-funded Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) study and she is one of the lead PI’s for the ISPY COVID clinical trial, a Phase 2 platform clinical trial of novel treatments for COVID-19 associated ARDS.
Research Funding
January 16, 2018 - December 31, 2024 - Precision Medicine in the Acute Respiratory Distress Syndrome , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R35HL140026
July 15, 2016 - June 30, 2021 - ARDS Endotypes: Expanded Analysis of Clinical and Biological Phenotypes and Evolution Over Time , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K24HL133390
March 15, 2016 - February 28, 2020 - Molecular Endotypes of ARDS: Identification, Biology, and Differential Response to Therapy , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01HL131621
September 19, 2013 - August 31, 2018 - Improved Models to Inform Tobacco Product Regulation , Co-Investigator . Sponsor: NIH/NCI, Sponsor Award ID: P50CA180890
Education
Yale University, BA, 1991-1995, English
University of Pennsylvania, MD, 1995-1999, Medicine
University of California, San Francisco Internship/Residency, 1999-2002, Internal Medicine
University of California, San Francisco Chief Residency, 2002-2003, Internal Medicine
University of California, San Francisco Fellowship, 2003-2007, Pulmonary/Critical Care
University of California, San Francisco Masters in Clinical Research (expected), 2007-2009, Clinical Research