University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Corey Raffel, MD, PhD

Corey Raffel, MD, PhD

Professor of Neurologic Surgery

Cancer Center Program Memberships

Neurologic Oncology

Education

University of California, San Diego, CA MD 06/80 Medicine
University of California, San Diego, CA PhD 06/80 Biology
University of California, San Francisco, CA Intern 07/80-06/80 General Surgery
University of California, San Francisco, CA Residency 07/80-06/86 Neurosurgery
Hospital for Sick Children, Toronto, Ontario,
Canada/UCSF, San Francisco CA Fellowship 07/86-06/87 Pediatric Neurosurgery
 


Professional Experience

  • 1/87-6/87 Clinical Instructor, Neurological Surgery, Univ. of California, San Francisco Academic Postitions
  • 7/87-6/92 Assistant Professor, Neurological Surgery, Univ. of Southern California School of Medicine
  • 7/92-7/95 Associate Professor, Neurological Surgery, Univ. of Southern California School of Medicine
  • 7/95-12/95 Senior Associate Consult. Neurological Surgery, Mayo Clinic/Mayo Foundation, Rochester, MN
  • 1/96-6/99 Associate Professor, Neurological Surgery, Mayo Clinic/Mayo Foundation, Rochester, MN
  • 7/99-11/07 Professor of Neurological Surgery, Mayo Clinic/Mayo Foundation, Rochester, MN
  • 12/07-present Professor of Neurologic Surgery, The Ohio State University College of Medicine, Columbus, OH
  • 07/08-present Vice Chair, Department of Neurologic Surgery, The Ohio State University College of Medicine, Columbus, OH
  • 1971-1974 National Scholar – Harvard University

Honors & Awards

  • 1974 Magna Cum Laude – Harvard University
  • 1974 Phi Beta Kappa
  • 1986 Preuss Foundation Award – Joint Section on Tumors of the American Association of
    Neurosurgeons/Congress of Neurosurgeons
  • Joint Section on Tumors, the American Association of Neurosurgeons/Congress of Neurosurgeons

Selected Publications

  1. Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, McDermott M, Berger M, Raffel C, Gupta N, Sun PP, Li Y, Shah V, Cha S, Braunstein S, Raleigh DR, Samuel D, Scharnhorst D, Fata C, Guo H, Moes G, Kim JYH, Koschmann C, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Phillips JJ, Tihan T, Bollen AW, Perry A, Solomon DA. Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas. Acta Neuropathol. 2019 Sep 12.
    View on PubMed
  2. Russell SJ, Babovic-Vuksanovic D, Bexon A, Cattaneo R, Dingli D, Dispenzieri A, Deyle DR, Federspiel MJ, Fielding A, Galanis E, Lacy MQ, Leibovich BC, Liu MC, Muñoz-Alía M, Miest TC, Molina JR, Mueller S, Okuno SH, Packiriswamy N, Peikert T, Raffel C, Van Rhee F, Ungerechts G, Young PR, Zhou Y, Peng KW. Oncolytic Measles Virotherapy and Opposition to Measles Vaccination. Mayo Clin Proc. 2019 Sep; 94(9):1834-1839.
    View on PubMed
  3. Ferris SP, Velazquez Vega J, Aboian M, Lee JC, Van Ziffle J, Onodera C, Grenert JP, Saunders T, Chen YY, Banerjee A, Kline CN, Gupta N, Raffel C, Samuel D, Ruiz-Diaz I, Magaki S, Wilson D, Neltner J, Al-Hajri Z, Phillips JJ, Pekmezci M, Bollen AW, Tihan T, Schniederjan M, Cha S, Perry A, Solomon DA. High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis. Brain Pathol. 2019 May 18.
    View on PubMed
  4. Lee JC, Mazor T, Lao R, Wan E, Diallo AB, Hill NS, Thangaraj N, Wendelsdorf K, Samuel D, Kline CN, Banerjee A, Auguste K, Raffel C, Gupta N, Berger M, Raleigh DR, Shai A, Phillips JJ, Bollen AW, Tihan T, Perry A, Costello J, Solomon DA. Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma. Acta Neuropathol. 2019 May; 137(5):851-854.
    View on PubMed
  5. Lal S, Carrera D, Phillips JJ, Weiss WA, Raffel C. An oncolytic measles virus-sensitive Group 3 medulloblastoma model in immune-competent mice. Neuro Oncol. 2018 11 12; 20(12):1606-1615.
    View on PubMed
  6. Lee J, Putnam AR, Chesier SH, Banerjee A, Raffel C, Van Ziffle J, Onodera C, Grenert JP, Bastian BC, Perry A, Solomon DA. Oligodendrogliomas, IDH-mutant and 1p/19q-codeleted, arising during teenage years often lack TERT promoter mutation that is typical of their adult counterparts. Acta Neuropathol Commun. 2018 09 19; 6(1):95.
    View on PubMed
  7. López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C, Gupta N, Kunwar S, Mummaneni P, Aghi M, Theodosopoulos P, Berger M, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA. The genetic landscape of gliomas arising after therapeutic radiation. Acta Neuropathol. 2019 Jan; 137(1):139-150.
    View on PubMed
  8. Sankar K, Kyono W, Raffel C, Nicolaides T. Suprasellar Germinoma Presenting with Slipped Capital Femoral Epiphysis: Case Report. Cureus. 2017 Dec 16; 9(12):e1954.
    View on PubMed
  9. Lal S, Raffel C. Using Cystine Knot Proteins as a Novel Approach to Retarget Oncolytic Measles Virus. Mol Ther Oncolytics. 2017 Dec 15; 7:57-66.
    View on PubMed
  10. Kline CN, Packer RJ, Hwang EI, Raleigh DR, Braunstein S, Raffel C, Bandopadhayay P, Solomon DA, Aboian M, Cha S, Mueller S. Case-based review: pediatric medulloblastoma. Neurooncol Pract. 2017 Sep; 4(3):138-150.
    View on PubMed
  11. Quintanilla-Bordás C, Nourbakhsh B, Strober J, Raffel C, Waubant E. Clinical Reasoning: A 16-year-old girl with subacute weakness and sensory loss. Neurology. 2017 06 06; 88(23):e225-e229.
    View on PubMed
  12. Kline CN, Joseph NM, Grenert JP, van Ziffle J, Talevich E, Onodera C, Aboian M, Cha S, Raleigh DR, Braunstein S, Torkildson J, Samuel D, Bloomer M, Campomanes AGA, Banerjee A, Butowski N, Raffel C, Tihan T, Bollen AW, Phillips JJ, Korn WM, Yeh I, Bastian BC, Gupta N, Mueller S, Perry A, Nicolaides T, Solomon DA. Targeted next-generation sequencing of pediatric neuro-oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy. Neuro Oncol. 2017 05 01; 19(5):699-709.
    View on PubMed
  13. Lal S, Peng KW, Steele MB, Jenks N, Ma H, Kohanbash G, Phillips JJ, Raffel C. Safety Study: Intraventricular Injection of a Modified Oncolytic Measles Virus into Measles-Immune, hCD46-Transgenic, IFNaRko Mice. Hum Gene Ther Clin Dev. 2016 12; 27(4):145-151.
    View on PubMed
  14. Hutzen B, Raffel C, Studebaker AW. Advances in the design and development of oncolytic measles viruses. Oncolytic Virother. 2015; 4:109-18.
    View on PubMed
  15. Studebaker AW, Hutzen B, Pierson CR, Shaffer TA, Raffel C, Jackson EM. Oncolytic measles virus efficacy in murine xenograft models of atypical teratoid rhabdoid tumors. Neuro Oncol. 2015 Dec; 17(12):1568-77.
    View on PubMed
  16. Ostling L, Raffel C. Complications following preresection shunting in patients with posterior fossa tumors. J Neurosurg Pediatr. 2015 Jan; 15(1):1-3.
    View on PubMed
  17. Muszynski JA, Nofziger R, Greathouse K, Nateri J, Hanson-Huber L, Steele L, Nicol K, Groner JI, Besner GE, Raffel C, Geyer S, El-Assal O, Hall MW. Innate immune function predicts the development of nosocomial infection in critically injured children. Shock. 2014 Oct; 42(4):313-21.
    View on PubMed
  18. Hutzen B, Bid HK, Houghton PJ, Pierson CR, Powell K, Bratasz A, Raffel C, Studebaker AW. Treatment of medulloblastoma with oncolytic measles viruses expressing the angiogenesis inhibitors endostatin and angiostatin. BMC Cancer. 2014 Mar 19; 14:206.
    View on PubMed
  19. Raffel C. Cerebellar tonsil position and Chiari malformation. J Neurosurg. 2013 Sep; 119(3):810-1.
    View on PubMed
  20. Hutzen B, Pierson CR, Russell SJ, Galanis E, Raffel C, Studebaker AW. Treatment of medulloblastoma using an oncolytic measles virus encoding the thyroidal sodium iodide symporter shows enhanced efficacy with radioiodine. BMC Cancer. 2012 Nov 07; 12:508.
    View on PubMed

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