University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Betty Smoot, DPTSc, PT

Betty Smoot, DPTSc, PT

Associate Professor, Dept. of Physical Therapy and Rehabilitation Science, UCSF

Cancer Center Program Memberships

Breast Oncology

Research Summary

My research focuses on breast cancer-related lymphedema (LE), a progressive and incurable condition that results from lymphatic system damage during cancer treatment. My research goals are to 1) to evaluate genetic and molecular mechanisms associated with increased risk for LE after breast cancer treatment and 2) to evaluate strategies to prevent and treat breast cancer-related lymphedema.

Education

San Francisco State University, BA, 05/81, Biology
University of California, San Francisco, Post-baccalaureate Certif., 09/83, Physical Therapy
University of California, San Francisco, Doctorate of Physical Therapy Science, 06/09, Physical Therapy and Rehabilitation Science
American College of Sports Medicine, Certification, 09/08, Cancer Exercise Trainer
Norton School of Lymphatic Therapy, Certification, 10/10, Lymphedema Therapist
University of California, San Francisco, Masters of Advanced Studies, 06/15, Clinical Research


Professional Experience

  • 1983 – 1988
    San Francisco Bay Area, Staff Physical Therapist
  • 1988 – 2010
    Sonoma Valley Hospital, Sonoma, CA, Lead Physical Therapist
  • 2010 – 2015
    UCSF Dept. of Physical Therapy and Rehabilitation Science, Assistant Professor (Primary Appointment)
  • 2010 – 2015
    UCSF Dept. of Anatomy, Assistant Professor (Joint Appointment)
  • 2015 – present
    UCSF Dept. of Physical Therapy and Rehabilitation Science, Associate Professor (Primary Appointment)
  • 2015 – present
    UCSF Dept. of Anatomy, Associate Professor (Joint Appointment)

Honors & Awards

  • 2006
    Kean Graduate Fellowship Award, University of California, San Francisco
  • 2008
    University of California, San Francisco Graduate Student Research Award
  • 2008
    California Physical Therapy Association Research Award
  • 2009>
    UCSF Graduate Division-Earle C. Anthony Travel Award
  • 2009
    Graduate Student Distinguished Achievement Award, San Francisco State University
  • 2010
    Norton School of Lymphedema, Medi Certified Lymphedema Therapist Scholarship
  • 2010
    American Association of Anatomist Training Program Scholarship
  • 2011
    California Physical Therapy Association Research Publication Award
  • 2012
    Haile T. Debas Academy of Medical Educators Excellence in Teaching Award
  • 2013
    Essential Core Teaching Award Commitment to Teaching
  • 2013
    UCSF-Kaiser Building Interdisciplinary Research Careers in Women’s Health K12 Award
  • 2014
    First Time Writers Award, Journal of Hand Therapy, American Society of Hand Therapists

Selected Publications

  1. Mazor M, Paul SM, Chesney MA, Chen LM, Smoot B, Topp K, Conley YP, Levine JD, Miaskowski C. Perceived stress is associated with a higher symptom burden in cancer survivors. Cancer. 2019 Sep 10.
    View on PubMed
  2. Petrovchich I, Kober KM, Wagner L, Paul SM, Abrams G, Chesney MA, Topp K, Smoot B, Schumacher M, Conley YP, Hammer M, Levine JD, Miaskowski C. Deleterious Effects of Higher Body Mass Index on Subjective and Objective Measures of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors. J Pain Symptom Manage. 2019 Aug; 58(2):252-263.
    View on PubMed
  3. Knisely MR, Conley YP, Smoot B, Paul SM, Levine JD, Miaskowski C. Associations Between Catecholaminergic and Serotonergic Genes and Persistent Arm Pain Severity Following Breast Cancer Surgery. J Pain. 2019 Sep; 20(9):1100-1111.
    View on PubMed
  4. Kober KM, Olshen A, Conley YP, Schumacher M, Topp K, Smoot B, Mazor M, Chesney M, Hammer M, Paul SM, Levine JD, Miaskowski C. Expression of mitochondrial dysfunction-related genes and pathways in paclitaxel-induced peripheral neuropathy in breast cancer survivors. Mol Pain. 2018 Jan-Dec; 14:1744806918816462.
    View on PubMed
  5. Mazor M, Smoot BJ, Mastick J, Mausisa G, Paul SM, Kober KM, Elboim C, Singh K, Conley YP, Mickevicius G, Field J, Hutchison H, Miaskowski C. Assessment of local tissue water in the arms and trunk of breast cancer survivors with and without upper extremity lymphoedema. Clin Physiol Funct Imaging. 2019 Jan; 39(1):57-64.
    View on PubMed
  6. Kober KM, Mazor M, Abrams G, Olshen A, Conley YP, Hammer M, Schumacher M, Chesney M, Smoot B, Mastick J, Paul SM, Levine JD, Miaskowski C. Phenotypic Characterization of Paclitaxel-Induced Peripheral Neuropathy in Cancer Survivors. J Pain Symptom Manage. 2018 12; 56(6):908-919.e3.
    View on PubMed
  7. Correll S, Field J, Hutchinson H, Mickevicius G, Fitzsimmons A, Smoot B. RELIABILITY AND VALIDITY OF THE HALO DIGITAL GONIOMETER FOR SHOULDER RANGE OF MOTION IN HEALTHY SUBJECTS. Int J Sports Phys Ther. 2018 Aug; 13(4):707-714.
    View on PubMed
  8. Mazor M, Cataldo JK, Lee K, Dhruva A, Paul SM, Smoot BJ, Dunn LB, Levine JD, Mastick J, Conley YP, Miaskowski C. Influence of Menopausal Status on the Symptom Experience of Women Before Breast Cancer Surgery. Cancer Nurs. 2018 Jul/Aug; 41(4):265-278.
    View on PubMed
  9. Bernas M, Thiadens SRJ, Smoot B, Armer JM, Stewart P, Granzow J. Lymphedema following cancer therapy: overview and options. Clin Exp Metastasis. 2018 08; 35(5-6):547-551.
    View on PubMed
  10. Knisely MR, Conley YP, Kober KM, Smoot B, Paul SM, Levine JD, Miaskowski C. Associations Between Catecholaminergic and Serotonergic Genes and Persistent Breast Pain Phenotypes After Breast Cancer Surgery. J Pain. 2018 10; 19(10):1130-1146.
    View on PubMed
  11. Miaskowski C, Paul SM, Mastick J, Abrams G, Topp K, Smoot B, Kober KM, Chesney M, Mazor M, Mausisa G, Schumacher M, Conley YP, Sabes JH, Cheung S, Wallhagen M, Levine JD. Associations Between Perceived Stress and Chemotherapy-Induced Peripheral Neuropathy and Otoxicity in Adult Cancer Survivors. J Pain Symptom Manage. 2018 07; 56(1):88-97.
    View on PubMed
  12. Mazor M, Cataldo JK, Lee K, Dhruva A, Cooper B, Paul SM, Topp K, Smoot BJ, Dunn LB, Levine JD, Conley YP, Miaskowski C. Differences in symptom clusters before and twelve months after breast cancer surgery. Eur J Oncol Nurs. 2018 Feb; 32:63-72.
    View on PubMed
  13. Mazor M, Lee K, Dhruva A, Cataldo JK, Paul SM, Melisko M, Smoot BJ, Levine JD, Elboim C, Conley YP, Miaskowksi C. Menopausal-Related Symptoms in Women One Year After Breast Cancer Surgery. J Pain Symptom Manage. 2018 04; 55(4):1138-1151.e1.
    View on PubMed
  14. Miaskowski C, Mastick J, Paul SM, Abrams G, Cheung S, Sabes JH, Kober KM, Schumacher M, Conley YP, Topp K, Smoot B, Mausisa G, Mazor M, Wallhagen M, Levine JD. Impact of chemotherapy-induced neurotoxicities on adult cancer survivors' symptom burden and quality of life. J Cancer Surviv. 2018 04; 12(2):234-245.
    View on PubMed
  15. Miaskowski C, Paul SM, Mastick J, Schumacher M, Conley YP, Smoot B, Abrams G, Kober KM, Cheung S, Henderson-Sabes J, Chesney M, Mazor M, Wallhagen M, Levine JD. Hearing loss and tinnitus in survivors with chemotherapy-induced neuropathy. Eur J Oncol Nurs. 2018 Feb; 32:1-11.
    View on PubMed
  16. Mazor M, Lee JQ, Peled A, Zerzan S, Irwin C, Chesney MA, Serrurier K, Sbitany H, Dhruva A, Sacks D, Smoot B. The Effect of Yoga on Arm Volume, Strength, and Range of Motion in Women at Risk for Breast Cancer-Related Lymphedema. J Altern Complement Med. 2018 Feb; 24(2):154-160.
    View on PubMed
  17. K. Kober, J. Mastick, S. Paul, K. Topp, B. Smoot, G. Abrams, L. Chen, Y. Conley, M. Chesney, K. Bolla, G. Mausisa, M. Azor, M. Wong, M. Schumacher, J. Levine, C. Miaskowski. (431) Characteristics of chemotherapy induced neuropathy (CIN) in cancer survivors who received taxol. Journal of Pain. 2017 Apr 1; 18(4):s82.
    View on PubMed
  18. Smoot B, Kober KM, Paul SM, Levine JD, Abrams G, Mastick J, Topp K, Conley YP, Miaskowski CA. Potassium Channel Candidate Genes Predict the Development of Secondary Lymphedema Following Breast Cancer Surgery. Nurs Res. 2017 Mar/Apr; 66(2):85-94.
    View on PubMed
  19. Judy Mastick, Grace Mausisa, Melissa Mazor, Steven M. Paul, Bruce A. Cooper, Betty Smoot, Kimberly Topp, Gary Abrams, Lee-may Chen, Margaret Chesney, Kord Kober, Yvette Conley, Jon Levine, Christine Miaskowski. Subgroups of survivors with distinct aggravating factors associated with chemotherapy-induced neuropathy (CIN) in the feet. Journal of Clinical Oncology. 2017 Feb 10; 35(5_suppl):151-151.
    View on PubMed
  20. Grace Mausisa, Judy Mastick, Melissa Mazor, Steven M. Paul, Bruce A. Cooper, Betty Smoot, Kimberly Topp, Gary Abrams, Lee-may Chen, Margaret Chesney, Kord Kober, Yvette Conley, Jon Levine, Christine Miaskowski. Subgroups of survivors with distinct aggravating factors associated with chemotherapy-induced neuropathy (CIN) in the hands. Journal of Clinical Oncology. 2017 Feb 10; 35(5_suppl):157-157.
    View on PubMed

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