University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Kyle Walsh, PhD

Kyle Walsh, PhD

Assistant Professor, School of Medicine, Department of Neurological Surgery, UCSF

Education

The Ohio State University, BS, 06/07, Molecular Genetics
The Ohio State University, BS, 06/07, Anthropology
The Yale University School of Medicine, PhD, 06/11, Genetic Epidemiology
The University of California, San Francisco, Postdoctoral, 08/13, Cancer Genetics
 

Professional Experience

  • 2005-2007
    The Ohio State University James Cancer Center, Clinical Research Associate, Department of Clinical Cancer Genetics
  • 2009-2011
    The Yale University School of Public Health, Research Associate, Center for Perinatal, Pediatric and Environmental Epidemiology
  • 2011-2013
    The University of California, San Francisco, Postdoctoral Scholar, Program in Cancer Genetics, Department of Epidemiology and Biostatistics
  • 2013-Present
    The University of California, San Francisco, Assistant Professor, Division of Neuroepidemiology, Dept. of Neurological Surgery

Honors & Awards

  • 2014
    Award for Excellence in Epidemiology Research
  • 2013
    Marvin Barker Award, The Society for Neuro-OncologyUCSF Brain Tumor Research Center
  • 2011, 2013
    BTEC Junior Investigator Award,, The Brain Tumor Epidemiology Consortium2011
    BTEC Junior Investigator Award, The Brain Tumor Epidemiology Consortium
  • 2011
    Master's degree awarded "With Distinction", The Yale University School of Public Health
  • 2007
    University Fellowship, The Yale University School of Public Health
  • 2007
    Outstanding Student Presentation in Human Genetics, American Association for Anthropological Genetics

Selected Publications

  1. Zhang C, Hansen HM, Semmes EC, Gonzalez-Maya J, Morimoto L, Wei Q, Eward WC, DeWitt SB, Hurst JH, Metayer C, de Smith AJ, Wiemels JL, Walsh KM. Common genetic variation and risk of osteosarcoma in a multi-ethnic pediatric and adolescent population. Bone. 2019 Sep 13; 115070.
    View on PubMed
  2. Brown AL, de Smith AJ, Gant VU, Yang W, Scheurer ME, Walsh KM, Chernus JM, Kallsen NA, Peyton SA, Davies GE, Ehli EA, Winick N, Heerema NA, Carroll AJ, Borowitz MJ, Wood BL, Carroll WL, Raetz EA, Feingold E, Devidas M, Barcellos LF, Hansen HM, Morimoto L, Kang AY, Smirnov I, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson P, Spector LG, Pombo-de-Oliveira MS, DeWan AT, Mullighan CG, Hunger SP, Pui CH, Loh ML, Zwick ME, Metayer C, Ma X, Mueller BA, Sherman SL, Wiemels JL, Relling MV, Yang JJ, Lupo PJ, Rabin KR. Inherited genetic susceptibility of acute lymphoblastic leukemia in Down syndrome. Blood. 2019 Jul 26.
    View on PubMed
  3. de Smith AJ, Walsh KM, Morimoto LM, Francis SS, Hansen HM, Jeon S, Gonseth S, Chen M, Sun H, Luna-Fineman S, Antillón F, Girón V, Kang AY, Smirnov I, Shao X, Whitehead TP, Barcellos LF, Jolly KW, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson PD, Pombo-de-Oliveira MS, Spector LG, DeWan AT, Mueller BA, Chiang C, Metayer C, Ma X, Wiemels JL. Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome. Leukemia. 2019 Jul 11.
    View on PubMed
  4. Muskens IS, Zhang C, de Smith AJ, Biegel JA, Walsh KM, Wiemels JL. Germline genetic landscape of pediatric central nervous system (CNS) tumors. Neuro Oncol. 2019 Jun 19.
    View on PubMed
  5. Feng Y, Liu H, Duan B, Liu Z, Abbruzzese J, Walsh KM, Zhang X, Wei Q. Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer. Carcinogenesis. 2019 Jun 10; 40(4):521-528.
    View on PubMed
  6. de Smith AJ, Lavoie G, Walsh KM, Aujla S, Evans E, Hansen HM, Smirnov I, Kang AY, Zenker M, Ceremsak JJ, Stieglitz E, Muskens IS, Roberts W, McKean-Cowdin R, Metayer C, Roux PP, Wiemels JL. Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children. Genes Chromosomes Cancer. 2019 10; 58(10):723-730.
    View on PubMed
  7. Yang W, Liu H, Duan B, Xu X, Carmody D, Luo S, Walsh KM, Abbruzzese JL, Zhang X, Chen X, Wei Q. Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk. Cancer Sci. 2019 Jun; 110(6):2022-2032.
    View on PubMed
  8. Walsh KM, Claus EB. Diet and risk of glioma: targets for prevention remain elusive. Neuro Oncol. 2019 Apr 23.
    View on PubMed
  9. Xu X, Qian D, Liu H, Cruz D, Luo S, Walsh KM, Abbruzzese JL, Zhang X, Wei Q. Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk. Mol Carcinog. 2019 Aug; 58(8):1338-1348.
    View on PubMed
  10. Takahashi H, Cornish AJ, Sud A, Law PJ, Disney-Hogg L, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Schildkraut JM, Simon M, Bondy M, Wrensch M, Wiemels JL, Claus EB, Turnbull C, Houlston RS. Mendelian randomization provides support for obesity as a risk factor for meningioma. Sci Rep. 2019 Jan 22; 9(1):309.
    View on PubMed
  11. Semmes EC, Zhang C, Walsh KM. Intermediate phenotypes underlying osteosarcoma risk. Oncotarget. 2018 Dec 21; 9(100):37345-37346.
    View on PubMed
  12. Claus EB, Cornish AJ, Broderick P, Schildkraut JM, Dobbins SE, Holroyd A, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Swerdlow A, Larsen SB, Johansen C, Simon M, Bondy M, Wrensch M, Houlston RS, Wiemels JL. Genome-wide association analysis identifies a meningioma risk locus at 11p15.5. Neuro Oncol. 2018 10 09; 20(11):1485-1493.
    View on PubMed
  13. de Smith AJ, Walsh KM, Francis SS, Zhang C, Hansen HM, Smirnov I, Morimoto L, Whitehead TP, Kang A, Shao X, Barcellos LF, McKean-Cowdin R, Zhang L, Fu C, Wang R, Yu H, Hoh J, Dewan AT, Metayer C, Ma X, Wiemels JL. BMI1 enhancer polymorphism underlies chromosome 10p12.31 association with childhood acute lymphoblastic leukemia. Int J Cancer. 2018 12 01; 143(11):2647-2658.
    View on PubMed
  14. Zhang C, Morimoto LM, de Smith AJ, Hansen HM, Gonzalez-Maya J, Endicott AA, Smirnov IV, Metayer C, Wei Q, Eward WC, Wiemels JL, Walsh KM. Genetic determinants of childhood and adult height associated with osteosarcoma risk. Cancer. 2018 09 15; 124(18):3742-3752.
    View on PubMed
  15. Mancini A, Xavier-Magalhães A, Woods WS, Nguyen KT, Amen AM, Hayes JL, Fellmann C, Gapinske M, McKinney AM, Hong C, Jones LE, Walsh KM, Bell RJA, Doudna JA, Costa BM, Song JS, Perez-Pinera P, Costello JF. Disruption of the ß1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner. Cancer Cell. 2018 09 10; 34(3):513-528.e8.
    View on PubMed
  16. Wallace AD, Wendt GA, Barcellos LF, de Smith AJ, Walsh KM, Metayer C, Costello JF, Wiemels JL, Francis SS. To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes. Front Genet. 2018; 9:298.
    View on PubMed
  17. Zhang C, Wiemels JL, Hansen HM, Gonzalez-Maya J, Endicott AA, de Smith AJ, Smirnov IV, Witte JS, Morimoto LM, Metayer C, Walsh KM. Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk. Cancer Epidemiol Biomarkers Prev. 2018 10; 27(10):1151-1158.
    View on PubMed
  18. Ojha J, Dyagil I, Finch SC, Reiss RF, de Smith AJ, Gonseth S, Zhou M, Hansen HM, Sherborne AL, Nakamura J, Bracci PM, Gudzenko N, Hatch M, Babkina N, Little MP, Chumak VV, Walsh KM, Bazyka D, Wiemels JL, Zablotska LB. Genomic characterization of chronic lymphocytic leukemia (CLL) in radiation-exposed Chornobyl cleanup workers. Environ Health. 2018 05 02; 17(1):43.
    View on PubMed
  19. Hayes J, Yu Y, Jalbert LE, Mazor T, Jones LE, Wood MD, Walsh KM, Bengtsson H, Hong C, Oberndorfer S, Roetzer T, Smirnov IV, Clarke JL, Aghi MK, Chang SM, Nelson SJ, Woehrer A, Phillips JJ, Solomon DA, Costello JF. Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas. Neuro Oncol. 2018 04 09; 20(5):632-641.
    View on PubMed
  20. Wiemels JL, Walsh KM, de Smith AJ, Metayer C, Gonseth S, Hansen HM, Francis SS, Ojha J, Smirnov I, Barcellos L, Xiao X, Morimoto L, McKean-Cowdin R, Wang R, Yu H, Hoh J, DeWan AT, Ma X. GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21. Nat Commun. 2018 01 18; 9(1):286.
    View on PubMed

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