University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Kyle Walsh, PhD

Kyle Walsh, PhD

Assistant Professor, School of Medicine, Department of Neurological Surgery, UCSF

Education

The Ohio State University, BS, 06/07, Molecular Genetics
The Ohio State University, BS, 06/07, Anthropology
The Yale University School of Medicine, PhD, 06/11, Genetic Epidemiology
The University of California, San Francisco, Postdoctoral, 08/13, Cancer Genetics
 

Professional Experience

  • 2005-2007
    The Ohio State University James Cancer Center, Clinical Research Associate, Department of Clinical Cancer Genetics
  • 2009-2011
    The Yale University School of Public Health, Research Associate, Center for Perinatal, Pediatric and Environmental Epidemiology
  • 2011-2013
    The University of California, San Francisco, Postdoctoral Scholar, Program in Cancer Genetics, Department of Epidemiology and Biostatistics
  • 2013-Present
    The University of California, San Francisco, Assistant Professor, Division of Neuroepidemiology, Dept. of Neurological Surgery

Honors & Awards

  • 2014
    Award for Excellence in Epidemiology Research
  • 2013
    Marvin Barker Award, The Society for Neuro-OncologyUCSF Brain Tumor Research Center
  • 2011, 2013
    BTEC Junior Investigator Award,, The Brain Tumor Epidemiology Consortium2011
    BTEC Junior Investigator Award, The Brain Tumor Epidemiology Consortium
  • 2011
    Master's degree awarded "With Distinction", The Yale University School of Public Health
  • 2007
    University Fellowship, The Yale University School of Public Health
  • 2007
    Outstanding Student Presentation in Human Genetics, American Association for Anthropological Genetics

Selected Publications

  1. Muskens IS, de Smith AJ, Zhang C, Hansen HM, Morimoto L, Metayer C, Ma X, Walsh KM, Wiemels JL. Germline cancer predisposition variants and pediatric glioma: a population-based study in California. Neuro Oncol. 2020 Jun 09; 22(6):864-874.
    View on PubMed
  2. Semmes EC, Vijayakrishnan J, Zhang C, Hurst JH, Houlston RS, Walsh KM. Leveraging genome and phenome-wide association studies to investigate genetic risk of acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev. 2020 May 28.
    View on PubMed
  3. Liu X, Qian D, Liu H, Abbruzzese JL, Luo S, Walsh KM, Wei Q. Genetic variants of the peroxisome proliferator-activated receptor (PPAR) signaling pathway genes and risk of pancreatic cancer. Mol Carcinog. 2020 May 05.
    View on PubMed
  4. Shen E, Xiu J, Bentley R, López GY, Walsh KM. Frequent Mutations of POT1 Distinguish Pulmonary Sarcomatoid Carcinoma From Other Lung Cancer Histologies. Clin Lung Cancer. 2020 Apr 15.
    View on PubMed
  5. Walsh KM. Telomere Attrition in Childhood Cancer Survivors. Clin Cancer Res. 2020 May 15; 26(10):2281-2283.
    View on PubMed
  6. Winer P, Muskens IS, Walsh KM, Vora A, Moorman AV, Wiemels JL, Roberts I, Roy A, de Smith AJ. Germline variants in predisposition genes in children with Down syndrome and acute lymphoblastic leukemia. Blood Adv. 2020 Feb 25; 4(4):672-675.
    View on PubMed
  7. Madsen TE, Khoury JC, Leppert M, Alwell K, Moomaw CJ, Sucharew H, Woo D, Ferioli S, Martini S, Adeoye O, Khatri P, Flaherty M, De Los Rios La Rosa F, Mackey J, Mistry E, Demel SL, Coleman E, Jasne A, Slavin SJ, Walsh K, Star M, Broderick JP, Kissela BM, Kleindorfer DO. Temporal Trends in Stroke Incidence Over Time by Sex and Age in the GCNKSS. Stroke. 2020 Apr; 51(4):1070-1076.
    View on PubMed
  8. Shen E, Xiu J, Lopez GY, Bentley R, Jalali A, Heimberger AB, Bainbridge MN, Bondy ML, Walsh KM. POT1 mutation spectrum in tumour types commonly diagnosed among POT1-associated hereditary cancer syndrome families. J Med Genet. 2020 Jan 14.
    View on PubMed
  9. Walsh KM. Epidemiology of meningiomas. Handb Clin Neurol. 2020; 169:3-15.
    View on PubMed
  10. Muskens IS, Zhang C, de Smith AJ, Biegel JA, Walsh KM, Wiemels JL. Germline genetic landscape of pediatric central nervous system tumors. Neuro Oncol. 2019 11 04; 21(11):1376-1388.
    View on PubMed
  11. Brown AL, de Smith AJ, Gant VU, Yang W, Scheurer ME, Walsh KM, Chernus JM, Kallsen NA, Peyton SA, Davies GE, Ehli EA, Winick N, Heerema NA, Carroll AJ, Borowitz MJ, Wood BL, Carroll WL, Raetz EA, Feingold E, Devidas M, Barcellos LF, Hansen HM, Morimoto L, Kang AY, Smirnov I, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson P, Spector LG, Pombo-de-Oliveira MS, DeWan AT, Mullighan CG, Hunger SP, Pui CH, Loh ML, Zwick ME, Metayer C, Ma X, Mueller BA, Sherman SL, Wiemels JL, Relling MV, Yang JJ, Lupo PJ, Rabin KR. Inherited genetic susceptibility to acute lymphoblastic leukemia in Down syndrome. Blood. 2019 10 10; 134(15):1227-1237.
    View on PubMed
  12. Zhang C, Hansen HM, Semmes EC, Gonzalez-Maya J, Morimoto L, Wei Q, Eward WC, DeWitt SB, Hurst JH, Metayer C, de Smith AJ, Wiemels JL, Walsh KM. Common genetic variation and risk of osteosarcoma in a multi-ethnic pediatric and adolescent population. Bone. 2020 Jan; 130:115070.
    View on PubMed
  13. Walsh KM, Claus EB. Diet and risk of glioma: targets for prevention remain elusive. Neuro Oncol. 2019 07 11; 21(7):832-833.
    View on PubMed
  14. de Smith AJ, Walsh KM, Morimoto LM, Francis SS, Hansen HM, Jeon S, Gonseth S, Chen M, Sun H, Luna-Fineman S, Antillón F, Girón V, Kang AY, Smirnov I, Shao X, Whitehead TP, Barcellos LF, Jolly KW, Healy J, Laverdière C, Sinnett D, Taub JW, Birch JM, Thompson PD, Pombo-de-Oliveira MS, Spector LG, DeWan AT, Mueller BA, Chiang C, Metayer C, Ma X, Wiemels JL. Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome. Leukemia. 2019 11; 33(11):2746-2751.
    View on PubMed
  15. Feng Y, Liu H, Duan B, Liu Z, Abbruzzese J, Walsh KM, Zhang X, Wei Q. Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer. Carcinogenesis. 2019 06 10; 40(4):521-528.
    View on PubMed
  16. de Smith AJ, Lavoie G, Walsh KM, Aujla S, Evans E, Hansen HM, Smirnov I, Kang AY, Zenker M, Ceremsak JJ, Stieglitz E, Muskens IS, Roberts W, McKean-Cowdin R, Metayer C, Roux PP, Wiemels JL. Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children. Genes Chromosomes Cancer. 2019 10; 58(10):723-730.
    View on PubMed
  17. Yang W, Liu H, Duan B, Xu X, Carmody D, Luo S, Walsh KM, Abbruzzese JL, Zhang X, Chen X, Wei Q. Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk. Cancer Sci. 2019 Jun; 110(6):2022-2032.
    View on PubMed
  18. Xu X, Qian D, Liu H, Cruz D, Luo S, Walsh KM, Abbruzzese JL, Zhang X, Wei Q. Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk. Mol Carcinog. 2019 08; 58(8):1338-1348.
    View on PubMed
  19. Takahashi H, Cornish AJ, Sud A, Law PJ, Disney-Hogg L, Calvocoressi L, Lu L, Hansen HM, Smirnov I, Walsh KM, Schramm J, Hoffmann P, Nöthen MM, Jöckel KH, Schildkraut JM, Simon M, Bondy M, Wrensch M, Wiemels JL, Claus EB, Turnbull C, Houlston RS. Mendelian randomization provides support for obesity as a risk factor for meningioma. Sci Rep. 2019 01 22; 9(1):309.
    View on PubMed
  20. Semmes EC, Zhang C, Walsh KM. Intermediate phenotypes underlying osteosarcoma risk. Oncotarget. 2018 Dec 21; 9(100):37345-37346.
    View on PubMed

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