Program/Disease Site Committees
The NCI requires that each Cancer Center have a Protocol Review and Monitoring System (PRMS) to assess scientific merit and feasibility of all protocols studying subjects diagnosed with, or at risk for, cancer conducted at the Center and to monitor for accrual and scientific relevance; NCI looks for centralized oversight across the Center.
While the centralized oversight is provided by the Protocol Review Committee (PRC), the Helen Diller Family Comprehensive Cancer Center provides for additional disease-specific input via the various Program/Disease Site Committees. These Program/Disease Site Committees are charged with the contextual review, feasibility assessment and prioritization of each new concept and protocol as it relates to the patient populations and research focus of each Program/Disease Site Committee. They consider relevant clinical programs, programmatic goals, expertise, and research interests in assessing both concepts and protocols. A protocol cannot move forward for review by the Protocol Review Committee (PRC) unless it has full approval from at least one Program/Disease Site Committee.
All studies reviewed by a Program/Disease Site Committee will be subject to:
Multiple Program/Disease Site Committees exist covering all disease areas, including one for supportive care and one for early phase trials.
> for Program/Disease Site Committee review process policies see ITR Policies