Kathleen Giacomini, PhD

University of Houston, Houston, TX, B.S., 1973, Pharmacy
State University of New York at Buffalo, Buffalo, NY, Ph.D., 1979, Pharmaceutical Sciences
Stanford University, Stanford, CA, Postdoc, 1979-81, Pharmacology /Clinical Pharmacology

• 1981-87
  Assistant Professor of Pharmacy/ Pharmaceutical Chem. & Pharmacology
• 1987-91
  Associate Professor of Pharmacy/ Pharmaceutical Chem. & Pharmacology
• 1998-2009
  Chair of the Department of Biopharmaceutical Sciences
• 1992-present
  Professor of Biopharmaceutical Sciences, Pharmaceutical Chemistry, and Cellular & Molecular Pharmacology, UCSF
• 2009-present
  Co-chair, Department of Bioengineering and Therapeutic Sciences, UCSF

• 1973
  Rho Chi, Honorary Pharmacy Fraternity
• 1983-84
  Long Foundation Award for Excellence in Teaching, School of Pharmacy, UCSF
• 1984-85
  UCSF Nominee, Recognition Award for Young Scholars, American Association of University Women
• 1985-86
  Distinguished Teaching Award, UCSF, Academic Senate
• 1990
  Leon Goldberg Young Investigator Award, American Society for Clinical Pharmacology and Therapeutics
• 1990-94
  Member of Pharmacological Science Review Committee; National Institutes of Health (GM)
• 1990-94
  Member of Generic Drugs Advisory Committee; Food and Drug Administration
• 1992
  Recipient, Fogarty International Fellowship; National Institutes of Health
• 1993
  Elected Fellow, American Association of Pharmaceutical Scientists
• 1994
  UCSF, Dr. Martin Luther King, Jr. Award for the Advancement of Women and Minorities
• 1996-97
  Vice President, American Society for Clinical Pharmacology and Therapeutics
• 1996-97
  UCSF, Chancellor's Award for the Advancement of Women
• 1999
  Recognition Award for Distinguished Achievement of Filipino at UCSF
• 1999
  International Pharmaceutical Federation (FIP), Pharmaceutical Scientist of the Year
• 2001
  Elected Fellow, American Association for the Advancement of Science
• 2002
  Distinguished Bill Abram's Lectureship (FDA)
• 2002
  First Distinguished Gerhard Levy Lectureship (SUNY Buffalo)
• 2002
  Speaker: State Legislative Presentation 'The Impact of the Human Genome Pronect on Drug Development and Use: Tailoring Drugs to Individuals'
• 2005
  Paul Dawson Biotechnology Award, American Association of College of Pharmacy
• 2006
  Distinguished Scientist in Drug Metabolism, American Association of Pharmaceutical Scientists
• 2006
  Elected Member, Institute of Medicine
• 2007
  International Pharmaceutical Sciences World Congress (PSWC) Research Achievement Award
• 2007
  International Woman Scientist Award, Academy of Pharmaceutical Sciences and Technology, Japan
• 2008
  Japan Society for the Promotion of Sciences (JSPS) Invitation Fellowship Program for Research in Japan
• 2009
  Rawls-Palmer Progress in Medicine Award, American Society for Clinical Pharmacology and Therapeutics (ASCPT)
• 2009
  UCSF Postdoctoral Scholars Association Outstanding Mentor Award
• 2010
  American College of Clinical Pharmacy Therapeutic Frontiers Lecture Award
• 2011
  Scheele Award, Swedish Academy of Pharmaceutical Sciences

• Kroetz,D.L., N. Ahituv, E.G. Burchard, S. Guo, A. Sali and K.M. Giacomini. The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapy. Pharmacogenomics 10(10): 1569-1576 (2009).
• Chen,L., M. Takizawa, E. Chen, A. Schlessinger, J.H. Choi, J. Segenthelar, A. Sali, M. Kubo, S. Nakamura, Y. Iwamoto, N. Iwasaki and K.M. Giacomini. Genetic Polymorphisms in the Organic Cation Transporter 1, OCT1, in Chinese and Japanese Populations, Exhibit Altered Function. J.Pharmacol.Exp.Ther. (2010).
• Shima,J.E., T. Komori, T.R. Taylor, D. Stryke, M. Kawamoto, S.J. Johns, E.J. Carlson, T.E. Ferrin and K.M. Giacomini. Genetic variants of human organic anion transporter 4 demonstrate altered transport of endogenous substrates. Am.J.Physiol.Renal Physiol. (2010).
• Picard,N., L. Levoir, F. Lamoureux, S.W. Yee, K.M. Giacomini and P. Marquet. Interaction of everolimus and sirolimus with the hepatic and intestinal Organic Anion Transporting Polypeptides (OATPs). Fundam.Clin.Pharmacol. 24457 (2010).
• Huang,S.M., L. Zhang and K.M. Giacomini. The International Transporter Consortium: A Collaborative Group of Scientists From Academia, Industry, and the FDA. Clinical Pharmacology & Therapeutics 87(1): 32-36 (2010).
• More,S.S., S. Li, S.W. Yee, L. Chen, Z. Xu, D.M. Jablons and K.M. Giacomini. Organic cation transporters modulate the uptake and cytotoxicity of picoplatin, a third-generation platinum analogue. Mol.Cancer.Ther. 9(4): 1058-1069 (2010).
• Kroetz,D.L., S.W. Yee and K.M. Giacomini. The Pharmacogenomics of Membrane Transporters Project: Research at the Interface of Genomics and Transporter Pharmacology. Clinical Pharmacology & Therapeutics 87(1): 109-116 (2010).
• Yee,S.W., L.G. Chen and K.M. Giacomini. Pharmacogenomics of membrane transporters: past, present and future. Pharmacogenomics 11(4): 475-479 (2010).
• Picard,N., S.W. Yee, J.B. Woillard, Y. Lebranchu, Y. Le Meur, K.M. Giacomini and P. Marquet. The Role of Organic Anion-Transporting Polypeptides and Their Common Genetic Variants in Mycophenolic Acid Pharmacokinetics. Clinical Pharmacology & Therapeutics 87(1): 100-108 (2010).
• More,S.S., O. Akil, A.G. Ianculescu, E.G. Geier, L.R. Lustig and K.M. Giacomini. Role of the copper transporter, CTR1, in platinum-induced ototoxicity. J.Neurosci. 30(28): 9500-9509 (2010).
• Ianculescu,A.G., E.C. Friesema, T.J. Visser, K.M. Giacomini and T.S. Scanlan. Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine. Mol.Biosyst 6(8): 1403-1410 (2010).
• Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KLR, Chu XY, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L, International Transporter. Membrane transporters in drug development. Nature Reviews Drug Discovery. 2010; 9(3): 215-236.
• Schlessinger A, Matsson P, Shima JE, Pieper U, Yee SW, Kelly L, Apeltsin L, Stroud RM, Ferrin TE, Giacomini KM, Sali A. Comparison of human solute carriers. Protein Science. 2010; 19(3): 412-428.