Andrei Goga, MD, PhD

University of California, Los Angeles, B.S., 1986-1990, Cell and Molecular Biology
University of California, Los Angeles, M.D., 1990-1997, Medicine
University of California, Los Angeles, Ph.D., 1990-1997, Molecular Biology
University of California, San Francisco, 1997-1999, Internal Medicine
University of California, San Francisco, 1999-2003, Medical Oncology

• 1/88-3/90
  Research Assistant, UCLA Dept. of Biology. Mentor: Asst. Professor J.M. Erickson, Ph.D.
• 6/90-5/95
  Medical Scientist Training Program, Univ. of California, Los Angeles. Ph.D. Advisor: Owen Witte, M.D.
• 7/97-6/98
  Intern, Department of Medicine, University of California, San Francisco.
• 7/98-6/99
  Resident, Department of Medicine, University of California, San Francisco.
• 7/99-8/03
  Medical Oncology Fellow, Division of Hematology/Oncology, University of California, San Francisco.
• 9/03-8/05
  Clinical Instructor, Division of Hematology/Oncology and G.W. Hooper Foundation, University of California, San Francisco.
• 8/05-9/06
  Adjunct Instructor, Division of Hematology/Oncology and G.W.Hooper Foundation, University of California, San Francisco
• 9/06-present
  Assistant Professor, Dept. of Medicine (Division of Hematology/Oncology), University of California, San Francisco

• 1986
  UCLA Alumni Association Scholarship
• 1986-1990
  University of California Regents Scholarship
• 1990
  Summa Cum Laude
• 1990
  Phi Beta Kappa Scholarship
• 1990-1997
  N.I.H. Medical Scientist Training Fellowship
• 5/97
  Emil Bogen Research Award, (most outstanding graduate research) UCLA School of Medicine
• 1997
  UCSF Molecular Medicine Fellow
• May, 2001
  Damon-Runyan Walter-Winchell Foundation Cancer Research Fellowship Award
• 9/01-8/04
  Howard Hughes Medical Institute Physician-Scientist Fellowship
• 2004
  Burroughs-Wellcome Career Awards in the Biomedical Sciences - Finalist

• Goga, A., McLaughlin, J., Pendergast, A.M., Parmar, K., Muller, A., Rosenberg, N., and Witte, O.N. 1993. Oncogenic activation of c-ABL by mutation within its last exon. Mol. Cell Biol. 13:4967-4975.
• Cohen, L., Mohr, R., Chen, Y.Y., Huang, M., Kato, R., Dorin, D., Tamanoi, F., Goga, A., Afar., D., Rosenberg, N., and Witte, O.N. 1994. Transcriptional activation of a novel ras-like gene (kir) by oncogenic tyrosine kinases. Proc. Nat. Acad. Sci. 91: 12448-12452.
• Sawyers, C.L., McLaughlin, J., Goga, A., Havlik, M., and Witte, O.N. 1994. The nuclear tyrosine kinase c-ABL negatively regulates cell growth. Cell 77: 121-31.
• Afar, D., Goga, A., McLaughlin, J., Witte, O.N., and Sawyers, C.S. 1994. Differential complementation of BCR/ABL point mutants with c-MYC. Science 264: 424-426.
• Goga, A., Liu, X., Hambuch, T., Senechal, K., Major, E., Berk, A.J., Witte, O.N., and Sawyers, C.L. 1995. p53 dependent growth suppression by the c-ABL nuclear tyrosine kinase. Oncogene 11: 791-799.
• Goga, A., McLaughlin, J., Afar, D.E.H., Saffran, D.C., and Witte, O.N. 1995. Alternative signals to Ras for hematopoietic transformation by the Bcr-Abl oncogene. Cell 82: 981-988.
• Walkenhorst, J. Goga, A., Witte, O. N., and Superti-Furga, G. 1996. Analysis of human c-Abl tyrosine kinase activity and regulation in S. Pombe. Oncogene, 12: 1513-20.
• Golub, T. R., Goga, A., Barker, G. F., Afar, D.E., McLaughlin, J., Bohlander, S. K., Rowley, J. D., Witte, O. N., and Gilliland, D. G. 1996. Oligomerization of the Abl tyrosine kinase by the Ets protein Tel in human leukemia. Mol. Cell Biol. 16: 4107-16.
• Yang, D., Buchholtz, F., Huang, Z., Goga, A., Chen, C., D.E., Brodsky, F. and Bishop, J.M. 2002. Short RNA duplexes produced by hydrolysis with Escheria coli RNase III mediate effective RNA interference in mammalian cells. Proc. Nat. Acad. Sci.99:9942-7.
• Yang D, Goga A, Bishop JM. 2004. RNA interference (RNAi) with RNase III-prepared siRNAs. Methods Mol Biol. 252:471-82.
• Scott G, Goga A, Bhaumik D, Berger C, Sullivan C, and Benz C. 2007. Coordinate Suppression of ERBB2 and ERBB3 by Enforced Expression of microRNA miR-125a or miR-125b. J. Biol Chem. 282(2):1479-86.
• Goga A, Yang, D, Tward A, Morgan DO and Bishop JM. 2007. Inhibition of Cdk1 as a potential therapy for tumors over-expressing MYC. Nature Medicine. Jul;13(7):820-7. Epub 2007 Jun 24.
• Goga A and Benz, C. 2007. Anti-oncomir suppression of tumor phenotypes. Mol Interv.Aug199-202.