(415) 885-3882 (appts)
(415) 353-9525 (fax)

Box 1674, UCSF; San Francisco, CA 94143-1674

additional websites:

UCSF Physician Referral Directory
Thoracic Oncology Lab

Yale University, New Haven, CT, B.A., 1979, American Lit.
Albany Medical College, Albany, NY, M.D., 1984, Medicine

(2004-present)

Maslyar DJ, Jahan TM, Jablons DM. Mechanisms of and potential treatment strategies for metastatic disease in non-small cell lung cancer. Semin Thorac Cardiovasc Surg, Issue: 1. 16: 40-50, 2004.

He B, You L, Uematsu K, Xu Z, Lee AY, Matsangou M, McCormick F, Jablons DM. A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells. Neoplasia, Issue: 1. 6: 7-14, 2004.

You L, He B, Xu Z, McCormick F, Jablons DM. Future directions: oncolytic viruses. Clin Lung Cancer, Issue: 4. 5: 226-30, Jan/2004.

Wang ZJ, Reddy GP, Gotway MB, Higgins CB, Jablons DM, Ramaswamy M, Hawkins RA, Webb WR. Malignant pleural mesothelioma: evaluation with CT, MR imaging, and PET. Radiographics, Issue: 1. 24: 105-19, 2004.

Corvera CU, Jablons D, Morita E, Clark OH. Retrocardiac parathyroid tumor: a rare mediastinal site. Surgery, Issue: 1. 135: 104-7, Jan/2004.

Mann MJ, Kramer MJ, Hall TS, Anastassiou P, Katz J, Golden J, Jones K, Jablons DM. Isolated pulmonary arteriovenous malformations requiring anatomic resection. J Thorac Cardiovasc Surg, Issue: 2. 127: 574-6, Feb/2004.

Nemunaitis J, Sterman D, Jablons D, Smith JW, Fox B, Maples P, Hamilton S, Borellini F, Lin A, Morali S, Hege K. Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer. J Natl Cancer Inst, Issue: 4. 96: 326-31, Feb/18/2004.

He B, You L, Xu Z, Mazieres J, Lee AY, Jablons DM. Activity of the suppressor of cytokine signaling-3 promoter in human non-small-cell lung cancer. Clin Lung Cancer, Issue: 6. 5: 366-70, May/2004.

You L, He B, Uematsu K, Xu Z, Mazieres J, Lee A, McCormick F, Jablons DM. Inhibition of Wnt-1 signaling induces apoptosis in beta-catenin-deficient mesothelioma cells. Cancer Res, Issue: 10. 64: 3474-8, May/15/2004.

Johnson DH, Fehrenbacher L, Novotny WF, Herbst RS, Nemunaitis JJ, Jablons DM, Langer CJ, DeVore RF, Gaudreault J, Damico LA, Holmgren E, Kabbinavar F. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol, Issue: 11. 22: 2184-91, Jun/1/2004.

Mazieres J, He B, You L, Xu Z, Lee AY, Mikami I, Reguart N, Rosell R, McCormick F, Jablons DM. Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer. Cancer Res, Issue: 14. 64: 4717-20, Jul/15/2004.

You L, He B, Xu Z, Uematsu K, Mazieres J, Fujii N, Mikami I, Reguart N, McIntosh JK, Kashani-Sabet M, McCormick F, Jablons DM. An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth. Cancer Res, Issue: 15. 64: 5385-9, Aug/1/2004.

Beseth BD, Cameron RB, Leland P, You L, Varricchio F, Kreitman RJ, Maki RA, Jablons DM, Husain SR, Puri RK. Interleukin-4 receptor cytotoxin as therapy for human malignant pleural mesothelioma xenografts. Ann Thorac Surg, Issue: 2. 78: 436-43; discussion 436-43, Aug/2004.

You L, He B, Xu Z, Uematsu K, Mazieres J, Mikami I, Reguart N, Moody TW, Kitajewski J, McCormick F, Jablons DM. Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. Oncogene, Issue: 36. 23: 6170-4, Aug/12/2004.

Lee AY, He B, You L, Dadfarmay S, Xu Z, Mazieres J, Mikami I, McCormick F, Jablons DM. Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene, Issue: 39. 23: 6672-6, Aug/26/2004.

Reguart N, He B, Xu Z, You L, Lee AY, Mazieres J, Mikami I, Batra S, Rosell R, McCormick F, Jablons DM. Cloning and characterization of the promoter of human Wnt inhibitory factor-1. Biochem Biophys Res Commun, Issue: 1. 323: 229-34, Oct/8/2004.

Lee AY, He B, You L, Xu Z, Mazieres J, Reguart N, Mikami I, Batra S, Jablons DM. Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma. Biochem Biophys Res Commun, Issue: 4. 323: 1246-50, Oct/29/2004.

Mikami I, You L, He B, Xu Z, Batra S, Lee AY, Mazieres J, Reguart N, Uematsu K, Koizumi K, Jablons DM. Efficacy of Wnt-1 monoclonal antibody in sarcoma cells. BMC Cancer, Issue: 1. 5: 53, 2005.

Carter YM, Shagrun L, Klein H, Katz J, Jablons DM. Salmonella infection in an anterior mediastinal mass. J Thorac Cardiovasc Surg, Issue: 1. 129: 228-30, Jan/2005.

He B, Lee AY, Dadfarmay S, You L, Xu Z, Reguart N, Mazieres J, Mikami I, McCormick F, Jablons DM. Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells. Cancer Res, Issue: 3. 65: 743-8, Feb/1/2005.

Dresler CM, Olak J, Herndon JE, Richards WG, Scalzetti E, Fleishman SB, Kernstine KH, Demmy T, Jablons DM, Kohman L, Daniel TM, Haasler GB, Sugarbaker DJ, , , ,. Phase III intergroup study of talc poudrage vs talc slurry sclerosis for malignant pleural effusion. Chest, Issue: 3. 127: 909-15, Mar/2005.

McCowin MJ, Hall TS, Babcock WD, Solinger LL, Hall KW, Jablons DM. Changes in radiographic abnormalities in organ donors: associations with lung transplantation. J Heart Lung Transplant, Issue: 3. 24: 323-30, Mar/2005.

Hansen EK, Krieg RM, Azar RJ, Jablons DM, Jahan TM, Zaloudek CJ. Unusual thoracic problems in patients with malignancies: case 3. Carcinoid tumor of the thymus. J Clin Oncol, Issue: 12. 23: 2859-61, Apr/20/2005.

He B, Reguart N, You L, Mazieres J, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations. Oncogene, Issue: 18. 24: 3054-8, Apr/21/2005.

Mazieres J, He B, You L, Xu Z, Jablons DM. Wnt signaling in lung cancer. Cancer Lett, Issue: 1. 222: 1-10, May/10/2005.

He B, Barg RN, You L, Xu Z, Reguart N, Mikami I, Batra S, Rosell R, Jablons DM. Wnt signaling in stem cells and non-small-cell lung cancer. Clin Lung Cancer, Issue: 1. 7: 54-60, Jul/2005.

Mazieres J, You L, He B, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene, Issue: 34. 24: 5396-400, Aug/11/2005.

Taron M, Ichinose Y, Rosell R, Mok T, Massuti B, Zamora L, Mate JL, Manegold C, Ono M, Queralt C, Jahan T, Sanchez JJ, Sanchez-Ronco M, Hsue V, Jablons D, Sanchez JM, Moran T. Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res, Issue: 16. 11: 5878-85, Aug/15/2005.

Mazieres J, You L, He B, Xu Z, Twogood S, Lee AY, Reguart N, Batra S, Mikami I, Jablons DM. Wnt2 as a new therapeutic target in malignant pleural mesothelioma. Int J Cancer, Issue: 2. 117: 326-32, Nov/1/2005.

Reguart N, He B, Taron M, You L, Jablons DM, Rosell R. The role of Wnt signaling in cancer and stem cells. Fut Oncol, Issue: 6. 1: 787-797, Dec/2005.

Kim KU, Wilson SM, Abayasiriwardana KS, Collins R, Fjellbirkeland L, Xu Z, Jablons DM, Nishimura SL, Broaddus VC. A novel in vitro model of human mesothelioma for studying tumor biology and apoptotic resistance. Am J Respir Cell Mol Biol, Issue: 6. 33: 541-8, Dec/2005.

You L, Kim J, He B, Xu Z, McCormick F, Jablons DM. Wnt-1 signal as a potential cancer therapeutic target. Drug News Perspect, Issue: 1. 19: 27-31, 2006.

Raz D, Jablons DM. Bronchioloalveolar Carcinoma Is Not Associated with Younger Age at Diagnosis: an Analysis of the SEER Database. J Thorac Oncol., (In Press) , 2006.

You L, Mazieres J, Xu Z, He B, Kuchenbecher K, Mikami I, Reguart N, McCormick F, Jablons DM. Recombinant Human WIF-1 Kills Non-Small Cell Lung Cancer Cells by Inhibiting Wnt Signaling Pathway. Oncogene., (In Press) , 2006.

Nemunaitis J, Jahan T, Ross H, Sterman D, Richards D, Fox B, Jablons D, Aimi J, Lin A, Hege K. Phase 1/2 trial of autologous tumor mixed with an allogeneic GVAX((R)) vaccine in advanced-stage non-small-cell lung cancer. Cancer Gene Ther, Jan/6/2006.

Rosell R, Cecere F, Cognetti F, Cuello M, Sanchez JM, Taron M, Reguart N, Jablons D. Future directions in the second-line treatment of non-small cell lung cancer. Semin Oncol, Issue: 1 Suppl 1. 33: S45-51, Feb/2006.

Raz DJ, He B, Rosell R, Jablons DM. Bronchioloalveolar carcinoma: a review. Clin Lung Cancer, Issue: 5. 7: 313-22, Mar/2006.

Lin YC, You L, Xu Z, He B, Mikami I, Thung E, Chou J, Kuchenbecker K, Kim J, Raz D, Yang CT, Chen JK, Jablons DM. Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines. Biochem Biophys Res Commun, Issue: 2. 341: 635-40, Mar/10/2006.

Batra S, Shi Y, Kuchenbecker KM, He B, Reguart N, Mikami I, You L, Xu Z, Lin YC, ClŽment G, Jablons DM. Wnt inhibitory factor-1, a Wnt antagonist, is silenced by promoter hypermethylation in malignant pleural mesothelioma. Biochem Biophys Res Commun, Issue: 4. 342: 1228-32, Apr/21/2006.

Leong SP, Cady B, Jablons DM, Garcia-Aguilar J, Reintgen D, Jakub J, Pendas S, Duhaime L, Cassell R, Gardner M, Giuliano R, Archie V, Calvin D, Mensha L, Shivers S, Cox C, Werner JA, Kitagawa Y, Kitajima M. Clinical patterns of metastasis. Cancer Metastasis Rev, Issue: 2. 25: 221-32, Jun/2006.

Raz DJ, He B, Rosell R, Jablons DM. Current concepts in bronchioloalveolar carcinoma biology. Clin Cancer Res, Issue: 12. 12: 3698-704, Jun/15/2006.

Zhou BB, Peyton M, He B, Liu C, Girard L, Caudler E, Lo Y, Baribaud F, Mikami I, Reguart N, Yang G, Li Y, Yao W, Vaddi K, Gazdar AF, Friedman SM, Jablons DM, Newton RC, Fridman JS, Minna JD, Scherle PA. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell, Issue: 1. 10: 39-50, Jul/2006.

5/4/07