Diane L. Barber, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Diane L. Barber, PhD

Professor and Vice Chair, Department of Cell and Tissue Biology, UCSF

barber@itsa.ucsf.edu

Phone: (415) 476-3764 (voice)
Box 0512, UCSF
San Francisco, CA 94143-0512

View on UCSF Profiles

Cancer Center Membership

Associate Member » Non-aligned

Additional Websites


Education

University of California, Davis, B.S., 1975, Biological Sciences
University of California, Davis, M.S., 1977, Physiology
University of California, Los Angeles, Ph.D., 1985, Anatomy


Professional Experience

  • 1977-1980
    Lecturer, Department of Biology, University of California, Los Angeles
  • 1980-1985
    Predoctoral Fellow, Department of Anatomy, University of California, Los Angeles
  • 1985-1987
    NIH Postdoctoral Fellow (NRSA), Department of Physiology, University of Massachusetts Medical Center, Worcester, MA
  • 1987-1991
    Assistant Professor, Department of Surgery/Section of Anatomy, Yale University
  • 1991-1995
    Assistant Professor, Departments of Stomatology and Surgery, UCSF
  • 1993-present
    Member, Biomedical Sciences Graduate Program, UCSF
  • 1995-2001
    Associate Professor, Departments of Stomatology and Surgery, UCSF
  • 2001-present
    Professor, Department of Cell and Tissue Biology (previously Stomatology), UCSF
  • 2005- present
    Vice Chair, Department of Cell and Tissue Biology, UCSF

Honors & Awards

  • 1985-87
    NIH Individual NRSA Postdoctoral Fellowship
  • 1986
    Joseph P. Healy Research Award, University of Massachusetts
  • 1995-2000
    Established Investigator, American Heart Association
  • 1998-present
    Editorial Board, American Journal of Physiology: Cell Physiology
  • 1998-1999
    American Heart Association, National Review Committee for Transport and Metabolism
  • 1998
    Innovation in Basic Sciences Award, UCSF
  • 2000-2002
    American Heart Association, Co-chair National Review Committee for Transport and Metabolism
  • 2001/2003
    Vice-chair/Chair, Gordon Conference on Molecular Pharmacology
  • 2001-2003
    Member, NIH CDF3 Study Section
  • 2003-present
    Editorial Board, Journal of Biological Chemistry
  • 2005
    Sandler Program Integrative Award

Selected Publications

  1. Grillo-Hill BK, Choi C, Jimenez-Vidal M, Barber DL. Increased H(+) efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression. Elife. 2015; 4.
    View on PubMed
  2. Rana MK, Srivastava J, Yang M, Chen CS, Barber DL. Hypoxia increases the abundance but not the assembly of extracellular fibronectin during epithelial cell transdifferentiation. J Cell Sci. 2015 Mar 15; 128(6):1083-9.
    View on PubMed
  3. LeClaire LL, Rana M, Baumgartner M, Barber DL. The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit. J Cell Biol. 2015 Jan 19; 208(2):161-70.
    View on PubMed
  4. Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity. Cancer Cell. 2014 Nov 10; 26(5):638-52.
    View on PubMed
  5. Grillo-Hill BK, Webb BA, Barber DL. Ratiometric imaging of pH probes. Methods Cell Biol. 2014; 123:429-48.
    View on PubMed
  6. Choi CH, Webb BA, Chimenti MS, Jacobson MP, Barber DL. pH sensing by FAK-His58 regulates focal adhesion remodeling. J Cell Biol. 2013 Sep 16; 202(6):849-59.
    View on PubMed
  7. Crevenna AH, Naredi-Rainer N, Schönichen A, Dzubiella J, Barber DL, Lamb DC, Wedlich-Söldner R. Electrostatics control actin filament nucleation and elongation kinetics. J Biol Chem. 2013 Apr 26; 288(17):12102-13.
    View on PubMed
  8. Schönichen A, Webb BA, Jacobson MP, Barber DL. Considering protonation as a posttranslational modification regulating protein structure and function. Annu Rev Biophys. 2013; 42:289-314.
    View on PubMed
  9. Gillis LC, Berry DM, Minden MD, McGlade CJ, Barber DL. Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia. Leukemia. 2013 Aug; 27(8):1666-76.
    View on PubMed
  10. Choi CH, Thomason PA, Zaki M, Insall RH, Barber DL. Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium. J Biol Chem. 2013 Jan 25; 288(4):2464-74.
    View on PubMed
  11. Nunomura W, Denker SP, Barber DL, Takakuwa Y, Gascard P. Characterization of cytoskeletal protein 4.1R interaction with NHE1 (Na(+)/H(+) exchanger isoform 1). Biochem J. 2012 Sep 15; 446(3):427-35.
    View on PubMed
  12. Narayanan A, LeClaire LL, Barber DL, Jacobson MP. Phosphorylation of the Arp2 subunit relieves auto-inhibitory interactions for Arp2/3 complex activation. PLoS Comput Biol. 2011 Nov; 7(11):e1002226.
    View on PubMed
  13. Haynes J, Srivastava J, Madson N, Wittmann T, Barber DL. Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression. Mol Biol Cell. 2011 Dec; 22(24):4750-64.
    View on PubMed
  14. Webb BA, Chimenti M, Jacobson MP, Barber DL. Dysregulated pH: a perfect storm for cancer progression. Nat Rev Cancer. 2011 Sep; 11(9):671-7.
    View on PubMed
  15. Bandyopadhyay S, Chiang CY, Srivastava J, Gersten M, White S, Bell R, Kurschner C, Martin C, Smoot M, Sahasrabudhe S, Barber DL, Chanda SK, Ideker T. A human MAP kinase interactome. Nat Methods. 2010 Oct; 7(10):801-5.
    View on PubMed
  16. Jiménez-Vidal M, Srivastava J, Putney LK, Barber DL. Nuclear-localized calcineurin homologous protein CHP1 interacts with upstream binding factor and inhibits ribosomal RNA synthesis. J Biol Chem. 2010 Nov 19; 285(47):36260-6.
    View on PubMed
  17. Choi CH, Patel H, Barber DL. Expression of actin-interacting protein 1 suppresses impaired chemotaxis of Dictyostelium cells lacking the Na+-H+ exchanger NHE1. Mol Biol Cell. 2010 Sep 15; 21(18):3162-70.
    View on PubMed
  18. Meima ME, Webb BA, Witkowska HE, Barber DL. The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors. J Biol Chem. 2009 Sep 25; 284(39):26666-75.
    View on PubMed
  19. Karydis A, Jimenez-Vidal M, Denker SP, Barber DL. Mislocalized scaffolding by the Na-H exchanger NHE1 dominantly inhibits fibronectin production and TGF-beta activation. Mol Biol Cell. 2009 Apr; 20(8):2327-36.
    View on PubMed
  20. Frantz C, Barreiro G, Dominguez L, Chen X, Eddy R, Condeelis J, Kelly MJ, Jacobson MP, Barber DL. Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding. J Cell Biol. 2008 Dec 1; 183(5):865-79.
    View on PubMed

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