Gabriele Bergers, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
bergers_gabriele

Professor, Brain Tumor Research Center (BTRC) and Departments of Neurological Surgery and Anatomy, UCSF
Neill H. and Linda S. Brownstein Endowed Chair in Brain Tumor Research, UCSF

gabriele.bergers@ucsf.edu

Phone: (415) 476-6786 (voice)
Box 0520, UCSF
San Francisco, CA 94158-0520

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Additional Websites


Education

University of Munich, Germany, B.S., 1988, Biochemistry
Max Planck Institute (MPI), Martinsried, Germany, M.S., 1989, Biochemistry/Virology
Institute for Molecular Pathology (IMP), University of Vienna, Austria, Ph.D., 1993, Molecular Biology/Genetics
University of California, San Francisco, Postdoctoral Fellow, 1994-1997, Cancer Biology


Professional Experience

  • 1999-2001
    Assistant Research Biochemist, Department of Biochemistry and Biophysics, UCSF
  • 2001-2005
    Assistant Professor, Brain Tumor Research Center and Departments of Neurosurgery, UCSF
  • 2005-2011
    Associate Professor, Brain Tumor Research Center and Departments of Neurosurgery and Anatomy, UCSF
  • 2011-present
    Professor, Brain Tumor Research Center and Departments of Neurosurgery and Anatomy, UCSF

Honors & Awards

  • 2002-2002
    American Cancer Society Award
  • 2003-2002
    V Foundation Scholar Award
  • 2002-2004
    Sydney Kimmel Scholar Award
  • 2004-2005
    Goldhirsh Foundation Award
  • 2005-2006
    Sandler Opportunity Award
  • 2005-Present
    Neill H. and Linda S. Brownstein Endowed Chair in Brain Tumor Research

Selected Publications

  1. Wang AS, Lodi A, Rivera LB, Izquierdo-Garcia JL, Firpo MA, Mulvihill SJ, Tempero MA, Bergers G, Ronen SM. HR-MAS MRS of the pancreas reveals reduced lipid and elevated lactate and taurine associated with early pancreatic cancer. NMR Biomed. 2014 Nov; 27(11):1361-70.
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  2. Rivera LB, Bergers G. Angiogenesis. Targeting vascular sprouts. Science. 2014 Jun 27; 344(6191):1449-50.
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  3. Hyvönen M, Enbäck J, Huhtala T, Lammi J, Sihto H, Weisell J, Joensuu H, Rosenthal-Aizman K, El-Andaloussi S, Langel U, Närvänen A, Bergers G, Laakkonen P. Novel target for Peptide-based imaging and treatment of brain tumors. Mol Cancer Ther. 2014 Apr; 13(4):996-1007.
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  4. Rivera L, Pandika M, Bergers G. Escape Mechanisms from Antiangiogenic Therapy: An Immune Cell's Perspective. Adv Exp Med Biol. 2014; 772:83-99.
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  5. Rivera LB, Bergers G. Location, Location, Location: Macrophage Positioning within Tumors Determines Pro- or Antitumor Activity. Cancer Cell. 2013 Dec 9; 24(6):687-9.
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  6. Jahangiri A, De Lay M, Miller LM, Carbonell WS, Hu YL, Lu K, Tom MW, Paquette J, Tokuyasu TA, Tsao S, Marshall R, Perry A, Bjorgan KM, Chaumeil MM, Ronen SM, Bergers G, Aghi MK. Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance. Clin Cancer Res. 2013 Apr 1; 19(7):1773-83.
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  7. Lu KV, Bergers G. Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma. CNS Oncol. 2013 Jan; 2(1):49-65.
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  8. Lu KV, Chang JP, Parachoniak CA, Pandika MM, Aghi MK, Meyronet D, Isachenko N, Fouse SD, Phillips JJ, Cheresh DA, Park M, Bergers G. VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell. 2012 Jul 10; 22(1):21-35.
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  9. Sugiarto S, Persson AI, Munoz EG, Waldhuber M, Lamagna C, Andor N, Hanecker P, Ayers-Ringler J, Phillips J, Siu J, Lim DA, Vandenberg S, Stallcup W, Berger MS, Bergers G, Weiss WA, Petritsch C. Asymmetry-defective oligodendrocyte progenitors are glioma precursors. Cancer Cell. 2011 Sep 13; 20(3):328-40.
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  10. Dvorak HF, Weaver VM, Tlsty TD, Bergers G. Tumor microenvironment and progression. J Surg Oncol. 2011 May 1; 103(6):468-74.
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  11. Persson AI, Petritsch C, Swartling FJ, Itsara M, Sim FJ, Auvergne R, Goldenberg DD, Vandenberg SR, Nguyen KN, Yakovenko S, Ayers-Ringler J, Nishiyama A, Stallcup WB, Berger MS, Bergers G, McKnight TR, Goldman SA, Weiss WA. Non-stem cell origin for oligodendroglioma. Cancer Cell. 2010 Dec 14; 18(6):669-82.
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  12. Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, Dang J, Dinca EB, Plaisier SB, Oderberg I, Lee Y, Chen Z, Caldwell JS, Xie Y, Loo JA, Seligson D, Chakravari A, Lee FY, Weinmann R, Cloughesy TF, Nelson SF, Bergers G, Graeber T, Furnari FB, James CD, Cavenee WK, Johns TG, Mischel PS. Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res. 2009 Sep 1; 69(17):6889-98.
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  13. Pàez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Viñals F, Inoue M, Bergers G, Hanahan D, Casanovas O. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell. 2009 Mar 3; 15(3):220-31.
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  14. Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer. 2008 Aug; 8(8):592-603.
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  15. Silber J, Lim DA, Petritsch C, Persson AI, Maunakea AK, Yu M, Vandenberg SR, Ginzinger DG, James CD, Costello JF, Bergers G, Weiss WA, Alvarez-Buylla A, Hodgson JG. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med. 2008; 6:14.
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  16. Du R, Petritsch C, Lu K, Liu P, Haller A, Ganss R, Song H, Vandenberg S, Bergers G. Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM. Neuro Oncol. 2008 Jun; 10(3):254-64.
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  17. Du R, Lu KV, Petritsch C, Liu P, Ganss R, Passegué E, Song H, Vandenberg S, Johnson RS, Werb Z, Bergers G. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell. 2008 Mar; 13(3):206-20.
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  18. Pietras K, Pahler J, Bergers G, Hanahan D. Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting. PLoS Med. 2008 Jan 29; 5(1):e19.
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  19. Lu K, Lamagna C, Bergers G. Chapter 3. Bone marrow-derived vascular progenitors and proangiogenic monocytes in tumors. Methods Enzymol. 2008; 445:53-82.
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  20. Chesler L, Goldenberg DD, Seales IT, Satchi-Fainaro R, Grimmer M, Collins R, Struett C, Nguyen KN, Kim G, Tihan T, Bao Y, Brekken RA, Bergers G, Folkman J, Weiss WA. Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma. Cancer Res. 2007 Oct 1; 67(19):9435-42.
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