Professor, Departments of Biochemistry/Biophysics and Microbiology/Immunology, UCSF
Morris Herzstein Endowed Chair in Biology and Physiology, UCSF
Additional Websites
Education
University of Melbourne, Melbourne, Australia, B.Sc., 1970, Biochemistry
University of Melbourne, Melbourne, Australia, M.Sc., 1972, Biochemistry
University of Cambridge, England, Ph.D., 1975, Molecular Biology
Yale University, New Haven, Connecticut, Postdoc., 1975-1977, Molecular and Cellular Biology
Professional Experience
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1970-1971
Graduate Research Student, Master of Science Degree course Department of Biochemistry, University of Melbourne, Australia
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1971-1974
Graduate Research Student, Division of Protein and Nucleic Acid Chemistry MRC Laboratory of Molecular Biology, Cambridge, England (Advisor: F. Sanger)
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1975-1977
Postdoctoral Fellow, Department of Biology, Yale University
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1978 Postdoctoral Fellow, Department of Biochemistry, University of California, San Francisco
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1978-1983
Assistant Professor, Department of Molecular Biology, University of California, Berkeley
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1983-1986
Associate Professor, Department of Molecular Biology, University of California, Berkeley
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1986-1990
Professor, Department of Molecular Biology, University of California, Berkeley
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1993-1999
Chair, Department of Microbiology Immunology, University of California, San Francisco
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1990-present
Professor, Departments of Biochemistry and Biophysics, and Microbiology and Immunology, University of California, San Francisco
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1996-present
Member, Breast Oncology Program (1996) and Genitourinary Oncology Program (1999), UCSF Comprehensive Cancer Center
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2001-present
Scientific Advisory Board, Division of Basic Science, Fred Hutchinson Cancer Research Center
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2003-present
Scientific Advisory Board, Huntsman Cancer Institute, University of Utah, Salt Lake City
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2003-2007
Member, National Advisory Council on Aging, National Institute of Aging, NIH
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2008-present
Member, National Academies of Sciences Committee on Science, Technology and the Law.
Honors & Awards
- Selected honors and awards since 2000. For complete list, see Blackburn Lab website.
- 2000
American Association for Cancer Research-G.H.A. Clowes Memorial Award - 2000
Elected, Institute of Medicine - 2000
American Cancer Society Medal of Honor - 2000
Elected, Fellow of the American Association for the Advancement of Science - 2001
AACR-Pezcoller Foundation International Award for Cancer Research - 2001
General Motors Cancer Research Foundation Alfred P. Sloan Award - 2003
26th Annual Bristol-Myers Squibb Award for Distinguished Achievement in Cancer Research - 2005
Kirk A. Landon-American Association for Cancer Research Prize for Basic Cancer Research - 2005
Benjamin Franklin Medal in Life Science - 2005
New York Academy of Medicine Medal - 2006
National Cancer Institute Alfred G. Knudson Award - 2006
Fifth annual Wiley Prize in Biomedical Sciences - 2006
Albert Lasker Award for Basic Medical Research - 2006
The 25th Meyenburg Prize - 2006
Elected, American Philosophical Society - 2007
Elected, Australian Academy of Science - 2007
TIME 100 Most Influential People in the World - 2008
L’Oreal UNESCO For Women In Science Award - 2008
Weizmann Women & Science Award: Weizmann Institute of Science - 2009
Nobel Prize in Physiology or Medicine
Selected Publications
- Listerman I, Sun J, Gazzaniga FS, Lukas JL, Blackburn EH. The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis. Cancer Res. 2013 May 1; 73(9):2817-28.
View on PubMed - Blackburn E, Chang J, Hücker M, Holmes AT, Christensen NB, Liang R, Bonn DA, Hardy WN, Rütt U, Gutowski O, Zimmermann MV, Forgan EM, Hayden SM. X-Ray Diffraction Observations of a Charge-Density-Wave Order in Superconducting Ortho-II YBa_{2}Cu_{3}O_{6.54} Single Crystals in Zero Magnetic Field. Phys Rev Lett. 2013 Mar 29; 110(13):137004.
View on PubMed - Belin BJ, Cimini BA, Blackburn EH, Mullins RD. Visualization of actin filaments and monomers in somatic cell nuclei. Mol Biol Cell. 2013 Apr; 24(7):982-94.
View on PubMed - Needham BL, Adler N, Gregorich S, Rehkopf D, Lin J, Blackburn EH, Epel ES. Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999-2002. Soc Sci Med. 2013 May; 85:1-8.
View on PubMed - Jacobs EG, Kroenke C, Lin J, Epel ES, Kenna HA, Blackburn EH, Rasgon NL. Accelerated Cell Aging in Female APOE-e4 Carriers: Implications for Hormone Therapy Use. PLoS One. 2013; 8(2):e54713.
View on PubMed - Dowd JB, Bosch JA, Steptoe A, Blackburn EH, Lin J, Rees-Clayton E, Aiello AE. Cytomegalovirus is associated with reduced telomerase activity in the Whitehall II cohort. Exp Gerontol. 2013 Apr; 48(4):385-90.
View on PubMed - Entringer S, Epel ES, Lin J, Buss C, Shahbaba B, Blackburn EH, Simhan HN, Wadhwa PD. Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length. Am J Obstet Gynecol. 2013 Feb; 208(2):134.e1-7.
View on PubMed - Bansal N, Whooley MA, Regan M, McCulloch CE, Ix JH, Epel E, Blackburn E, Lin J, Hsu CY. Association between Kidney Function and Telomere Length: The Heart and Soul Study. Am J Nephrol. 2012; 36(5):405-11.
View on PubMed - Blackburn EH, Epel ES. Telomeres and adversity: Too toxic to ignore. Nature. 2012 Oct 11; 490(7419):169-71.
View on PubMed - Beery AK, Lin J, Biddle JS, Francis DD, Blackburn EH, Epel ES. Chronic stress elevates telomerase activity in rats. Biol Lett. 2012 Dec 23; 8(6):1063-6.
View on PubMed - Kiecolt-Glaser JK, Epel ES, Belury MA, Andridge R, Lin J, Glaser R, Malarkey WB, Hwang BS, Blackburn E. Omega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial. Brain Behav Immun. 2013 Feb; 28:16-24.
View on PubMed - Armanios M, Blackburn EH. The telomere syndromes. Nat Rev Genet. 2012 Oct; 13(10):693-704.
View on PubMed - Adler N, Pantell MS, O'Donovan A, Blackburn E, Cawthon R, Koster A, Opresko P, Newman A, Harris TB, Epel E. Educational attainment and late life telomere length in the Health, Aging and Body Composition Study. Brain Behav Immun. 2013 Jan; 27(1):15-21.
View on PubMed - Needham BL, Fernandez JR, Lin J, Epel ES, Blackburn EH. Socioeconomic status and cell aging in children. Soc Sci Med. 2012 Jun; 74(12):1948-51.
View on PubMed - Lavretsky H, Epel ES, Siddarth P, Nazarian N, Cyr NS, Khalsa DS, Lin J, Blackburn E, Irwin MR. A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: effects on mental health, cognition, and telomerase activity. Int J Geriatr Psychiatry. 2013 Jan; 28(1):57-65.
View on PubMed - O'Donovan A, Tomiyama AJ, Lin J, Puterman E, Adler NE, Kemeny M, Wolkowitz OM, Blackburn EH, Epel ES. Stress appraisals and cellular aging: A key role for anticipatory threat in the relationship between psychological stress and telomere length. Brain Behav Immun. 2012 May; 26(4):573-9.
View on PubMed - Daubenmier J, Lin J, Blackburn E, Hecht FM, Kristeller J, Maninger N, Kuwata M, Bacchetti P, Havel PJ, Epel E. Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study. Psychoneuroendocrinology. 2012 Jul; 37(7):917-28.
View on PubMed - Tomiyama AJ, O'Donovan A, Lin J, Puterman E, Lazaro A, Chan J, Dhabhar FS, Wolkowitz O, Kirschbaum C, Blackburn E, Epel E. Does cellular aging relate to patterns of allostasis? An examination of basal and stress reactive HPA axis activity and telomere length. Physiol Behav. 2012 Apr 12; 106(1):40-5.
View on PubMed - Krauss J, Farzaneh-Far R, Puterman E, Na B, Lin J, Epel E, Blackburn E, Whooley MA. Physical fitness and telomere length in patients with coronary heart disease: findings from the Heart and Soul Study. PLoS One. 2011; 6(11):e26983.
View on PubMed - Kroenke CH, Pletcher MJ, Lin J, Blackburn E, Adler N, Matthews K, Epel E. Telomerase, telomere length, and coronary artery calcium in black and white men in the CARDIA study. Atherosclerosis. 2012 Feb; 220(2):506-12.
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