University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Paul D. Blanc, MD, MSPH

Paul D. Blanc, MD, MSPH

Professor, Department of Medicine, UCSF

Cancer Center Program Memberships

Affiliate Member

Research Summary

My research program focuses primarily on the epidemiology and toxicology of the pulmonary system, with additional research work on injury epidemiology (including poisoning and drug overdose) and on the history of occupational health. My research program has been composed of two principal components: (1) examining the etiologic burden and outcomes of lung disease, with an emphasis on interactions between workplace exposures and disease severity; and (2) epidemiologic and controlled human exposure studies of toxin and drug exposure effects. Outcomes in adult asthma, COPD, and interstitial disease comprise the principal thrust of these research efforts.

Education

Goddard College, Plainfield, Vermont, BA, 1974, Liberal Arts
Harvard School of Public Health, Boston, MA MSPH, 1977, Industrial Hygiene
Albert Einstein School of Medicine, Bronx, NY, MD, 1982, Medicine

Honors & Awards

  • 2011
    Elected Fellow, Collegium Ramazzini
  • 2011
    Snell Memorial Lecturer, British Respiratory Society Winter Meeting
  • 2012
    Occupational Health Nursing Hero Award, UCSF School of Nursing,
  • 2013
    Jarsolav Teisinger Medal, Society of Occupational Medicine of the Czech Medical Society
  • 2013-2014
    Mellon Fellow, Center for Advanced Studies in the Behavioral Sciences, Stanford University
  • 2016
    Honorary Doctorate, Sahlgrenska Medical Academy, Gothenburg, Sweden
  • 2017
    Viseltear Prize, American Public Health Association, for “Outstanding Book on the History of Public Health.”
  • 2019
    Excellence in Education and Research in Occupational and Environmental Medicine Award, American College of Occupational and Environmental Medicine

Selected Publications

  1. Delfosse V, Huet T, Harrus D, Granell M, Bourguet M, Gardia-Parège C, Chiavarina B, Grimaldi M, Le Mével S, Blanc P, Huang D, Gruszczyk J, Demeneix B, Cianférani S, Fini JB, Balaguer P, Bourguet W. Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Proc Natl Acad Sci U S A. 2021 Jan 05; 118(1).
    View on PubMed
  2. Vinnikov D, Tulekov Z, Romanova Z, Krugovykh I, Blanc PD. Smoking practices in relation to exhaled carbon monoxide in an occupational cohort. BMC Public Health. 2020 Dec 09; 20(1):1894.
    View on PubMed
  3. Lytras T, Beckmeyer-Borowko A, Kogevinas M, Kromhout H, Carsin AE, Antó JM, Bentouhami H, Weyler J, Heinrich J, Nowak D, Urrutia I, Martínez-Moratalla J, Gullón JA, Pereira Vega A, Raherison Semjen C, Pin I, Demoly P, Leynaert B, Villani S, Gislason T, Svanes Ø, Holm M, Forsberg B, Norbäck D, Mehta AJ, Keidel D, Vernez D, Benke G, Jõgi R, Torén K, Sigsgaard T, Schlünssen V, Olivieri M, Blanc PD, Watkins J, Bono R, Squillacioti G, Buist AS, Vermeulen R, Jarvis D, Probst-Hensch N, Zock JP. Cumulative Occupational Exposures and Lung Function Decline in Two Large General Population Cohorts. Ann Am Thorac Soc. 2020 Oct 22.
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  4. Barnes H, Olin AC, Torén K, McSharry C, Donnelly I, Lärstad M, Iribarren C, Quinlan P, Blanc PD. Occupation versus environmental factors in hypersensitivity pneumonitis: population attributable fraction. ERJ Open Res. 2020 Oct; 6(4).
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  5. Domeracki S, Clapp RN, Taylor K, Lu CM, Lampiris H, Blanc PD. Cycle Threshold to Test Positivity in COVID-19 for Return to Work Clearance in Health Care Workers. J Occup Environ Med. 2020 Aug 13.
    View on PubMed
  6. Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden J, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Venado A, Kukreja J, Blanc PD, Singer JP. Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression. Am J Transplant. 2020 Aug 13.
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  7. Melamed J, Gerona R, Blanc PD, Takamoto P, Conner S, Goodnough R. Gamma-Butyrolactone Overdose Potentially Complicated by Co-Ingestion of Industrial Solvent N-Methyl-2-pyrrolidone. J Anal Toxicol. 2020 Jul 16.
    View on PubMed
  8. Torén K, Blanc PD, Qvarfordt I, Aspevall O, Schiöler L. Inhaled Corticosteroids Use and Risk of Invasive Pneumococcal Disease in a Population-based Study. Ann Am Thorac Soc. 2020 Jul 10.
    View on PubMed
  9. Garshick E, Blanc PD. Military Deployment and Respiratory Symptoms: Some Answers, Many Questions. Chest. 2020 Jun; 157(6):1407-1408.
    View on PubMed
  10. Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD, Singer JP. Frailty after lung transplantation is associated with impaired health-related quality of life and mortality. Thorax. 2020 08; 75(8):669-678.
    View on PubMed
  11. Torén K, Blanc PD, Naidoo RN, Murgia N, Qvarfordt I, Aspevall O, Dahlman-Hoglund A, Schioler L. Occupational exposure to dust and to fumes, work as a welder and invasive pneumococcal disease risk. Occup Environ Med. 2020 02; 77(2):57-63.
    View on PubMed
  12. Blanc PD, Redlich CA. Reply to Lee and Strek: Occupational Burden in Chronic Respiratory Disease: Call for Recognition, Training, and Data Capture. Am J Respir Crit Care Med. 2019 12 15; 200(12):1559.
    View on PubMed
  13. Kolaitis NA, Calabrese DR, Ahearn P, Venado A, Florez R, Lei HL, Isaak K, Henricksen E, Martinez E, Chong T, Shah RJ, Leard LE, Kleinhenz ME, Golden J, De Marco T, Greenland JR, Kukreja J, Hays SR, Blanc PD, Singer JP. Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients. Am J Health Syst Pharm. 2019 12 02; 76(24):2019-2027.
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  14. Blanc PD. What has been done will be done again. Respirology. 2019 12; 24(12):1125-1126.
    View on PubMed
  15. Shahbaz M, Blanc PD, Domeracki SJ, Guntur S. Shoulder Injury Related to Vaccine Administration (SIRVA): An Occupational Case Report. Workplace Health Saf. 2019 Oct; 67(10):501-505.
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  16. Schmajuk G, Trupin L, Yelin E, Blanc PD. Prevalence of Arthritis and Rheumatoid Arthritis in Coal Mining Counties of the United States. Arthritis Care Res (Hoboken). 2019 09; 71(9):1209-1215.
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  17. Garshick E, Abraham JH, Baird CP, Ciminera P, Downey GP, Falvo MJ, Hart JE, Jackson DA, Jerrett M, Kuschner W, Helmer DA, Jones KD, Krefft SD, Mallon T, Miller RF, Morris MJ, Proctor SP, Redlich CA, Rose CS, Rull RP, Saers J, Schneiderman AI, Smith NL, Yiallouros P, Blanc PD. Respiratory Health after Military Service in Southwest Asia and Afghanistan. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2019 08; 16(8):e1-e16.
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  18. Blanc PD, Annesi-Maesano I, Balmes JR, Cummings KJ, Fishwick D, Miedinger D, Murgia N, Naidoo RN, Reynolds CJ, Sigsgaard T, Torén K, Vinnikov D, Redlich CA. The Occupational Burden of Nonmalignant Respiratory Diseases. An Official American Thoracic Society and European Respiratory Society Statement. Am J Respir Crit Care Med. 2019 06 01; 199(11):1312-1334.
    View on PubMed
  19. Greenland JR, Wang P, Brotman JJ, Ahuja R, Chong TA, Kleinhenz ME, Leard LE, Golden JA, Hays SR, Kukreja J, Singer JP, Rajalingam R, Jones K, Laszik ZG, Trivedi NN, Greenland NY, Blanc PD. Gene signatures common to allograft rejection are associated with lymphocytic bronchitis. Clin Transplant. 2019 05; 33(5):e13515.
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  20. Venado A, McCulloch C, Greenland JR, Katz P, Soong A, Shrestha P, Hays S, Golden J, Shah R, Leard LE, Kleinhenz ME, Kukreja J, Zablotska L, Allen IE, Covinsky K, Blanc P, Singer JP. Frailty trajectories in adult lung transplantation: A cohort study. J Heart Lung Transplant. 2019 07; 38(7):699-707.
    View on PubMed

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