University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Paul D. Blanc, MD, MSPH

Paul D. Blanc, MD, MSPH

Professor, Department of Medicine, UCSF

Cancer Center Program Memberships

Affiliate Member

Research Summary

My research program focuses primarily on the epidemiology and toxicology of the pulmonary system, with additional research work on injury epidemiology (including poisoning and drug overdose) and on the history of occupational health. My research program has been composed of two principal components: (1) examining the etiologic burden and outcomes of lung disease, with an emphasis on interactions between workplace exposures and disease severity; and (2) epidemiologic and controlled human exposure studies of toxin and drug exposure effects. Outcomes in adult asthma, COPD, and interstitial disease comprise the principal thrust of these research efforts.

Education

Goddard College, Plainfield, Vermont, BA, 1974, Liberal Arts
Harvard School of Public Health, Boston, MA MSPH, 1977, Industrial Hygiene
Albert Einstein School of Medicine, Bronx, NY, MD, 1982, Medicine

Honors & Awards

  • 1975-1977
    NIOSH Training Grant, Harvard School of Public Health
  • 1985-1987
    Robert Wood Johnson Foundation Clinical Scholar
  • 1987-1988
    Fulbright Award, Senior Research Fellow
  • 1989-1991
    Research Award, American Lung Association of California Research Fund
  • 1990-1993
    Special Emphasis Research Career Award, NIOSH (CDC)
  • 1991-1994
    New Investigator Award, UC Tobacco Related Diseases Research Program
  • 1998
    Burroughs Wellcome Travel Award
  • 1999
    Rockefeller Foundation Bellagio Center Fellow
  • 2002
    Visiting Scholar, American Academy in Rome
  • 2005
    Dozer Visiting Professor, Ben Gurion University, Beer Sheva, Israel
  • 2007
    Jubilee Medal recipient, Swedish Medical Society, Section of Occupational and Environmental Medicine

Selected Publications

  1. Domeracki S, Clapp RN, Taylor K, Lu CM, Lampiris H, Blanc PD. Cycle Threshold to Test Positivity in COVID-19 for Return to Work Clearance in Health Care Workers. J Occup Environ Med. 2020 Aug 13.
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  2. Kolaitis NA, Gao Y, Soong A, Greenland JR, Hays SR, Golden J, Leard LE, Shah RJ, Kleinhenz ME, Katz PP, Venado A, Kukreja J, Blanc PD, Singer JP. Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression. Am J Transplant. 2020 Aug 13.
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  3. Melamed J, Gerona R, Blanc PD, Takamoto P, Conner S, Goodnough R. Gamma-Butyrolactone Overdose Potentially Complicated by Co-Ingestion of Industrial Solvent N-Methyl-2-pyrrolidone. J Anal Toxicol. 2020 Jul 16.
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  4. Torén K, Blanc PD, Qvarfordt I, Aspevall O, Schiöler L. Inhaled Corticosteroids Use and Risk of Invasive Pneumococcal Disease Risk in a Population-based Study. Ann Am Thorac Soc. 2020 Jul 10.
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  5. Garshick E, Blanc PD. Military Deployment and Respiratory Symptoms: Some Answers, Many Questions. Chest. 2020 Jun; 157(6):1407-1408.
    View on PubMed
  6. Venado A, Kolaitis NA, Huang CY, Gao Y, Glidden DV, Soong A, Sutter N, Katz PP, Greenland JR, Calabrese DR, Hays SR, Golden JA, Shah RJ, Leard LE, Kukreja J, Deuse T, Wolters PJ, Covinsky K, Blanc PD, Singer JP. Frailty after lung transplantation is associated with impaired health-related quality of life and mortality. Thorax. 2020 08; 75(8):669-678.
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  7. Torén K, Blanc PD, Naidoo RN, Murgia N, Qvarfordt I, Aspevall O, Dahlman-Hoglund A, Schioler L. Occupational exposure to dust and to fumes, work as a welder and invasive pneumococcal disease risk. Occup Environ Med. 2020 02; 77(2):57-63.
    View on PubMed
  8. Blanc PD, Redlich CA. Reply to Lee and Strek: Occupational Burden in Chronic Respiratory Disease: Call for Recognition, Training, and Data Capture. Am J Respir Crit Care Med. 2019 12 15; 200(12):1559.
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  9. Kolaitis NA, Calabrese DR, Ahearn P, Venado A, Florez R, Lei HL, Isaak K, Henricksen E, Martinez E, Chong T, Shah RJ, Leard LE, Kleinhenz ME, Golden J, De Marco T, Greenland JR, Kukreja J, Hays SR, Blanc PD, Singer JP. Tacrolimus trough monitoring guided by mass spectrometry without accounting for assay differences is associated with acute kidney injury in lung transplant recipients. Am J Health Syst Pharm. 2019 12 02; 76(24):2019-2027.
    View on PubMed
  10. Blanc PD. What has been done will be done again. Respirology. 2019 12; 24(12):1125-1126.
    View on PubMed
  11. Shahbaz M, Blanc PD, Domeracki SJ, Guntur S. Shoulder Injury Related to Vaccine Administration (SIRVA): An Occupational Case Report. Workplace Health Saf. 2019 Oct; 67(10):501-505.
    View on PubMed
  12. Schmajuk G, Trupin L, Yelin E, Blanc PD. Prevalence of Arthritis and Rheumatoid Arthritis in Coal Mining Counties of the United States. Arthritis Care Res (Hoboken). 2019 09; 71(9):1209-1215.
    View on PubMed
  13. Garshick E, Abraham JH, Baird CP, Ciminera P, Downey GP, Falvo MJ, Hart JE, Jackson DA, Jerrett M, Kuschner W, Helmer DA, Jones KD, Krefft SD, Mallon T, Miller RF, Morris MJ, Proctor SP, Redlich CA, Rose CS, Rull RP, Saers J, Schneiderman AI, Smith NL, Yiallouros P, Blanc PD. Respiratory Health after Military Service in Southwest Asia and Afghanistan. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2019 08; 16(8):e1-e16.
    View on PubMed
  14. Blanc PD, Annesi-Maesano I, Balmes JR, Cummings KJ, Fishwick D, Miedinger D, Murgia N, Naidoo RN, Reynolds CJ, Sigsgaard T, Torén K, Vinnikov D, Redlich CA. The Occupational Burden of Nonmalignant Respiratory Diseases. An Official American Thoracic Society and European Respiratory Society Statement. Am J Respir Crit Care Med. 2019 06 01; 199(11):1312-1334.
    View on PubMed
  15. Greenland JR, Wang P, Brotman JJ, Ahuja R, Chong TA, Kleinhenz ME, Leard LE, Golden JA, Hays SR, Kukreja J, Singer JP, Rajalingam R, Jones K, Laszik ZG, Trivedi NN, Greenland NY, Blanc PD. Gene signatures common to allograft rejection are associated with lymphocytic bronchitis. Clin Transplant. 2019 05; 33(5):e13515.
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  16. Venado A, McCulloch C, Greenland JR, Katz P, Soong A, Shrestha P, Hays S, Golden J, Shah R, Leard LE, Kleinhenz ME, Kukreja J, Zablotska L, Allen IE, Covinsky K, Blanc P, Singer JP. Frailty trajectories in adult lung transplantation: A cohort study. J Heart Lung Transplant. 2019 07; 38(7):699-707.
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  17. Lytras T, Kogevinas M, Kromhout H, Carsin AE, Antó JM, Bentouhami H, Weyler J, Heinrich J, Nowak D, Urrutia I, Martínez-Moratalla J, Gullón JA, Vega AP, Raherison Semjen C, Pin I, Demoly P, Leynaert B, Villani S, Gíslason T, Svanes Ø, Holm M, Forsberg B, Norbäck D, Mehta AJ, Probst-Hensch N, Benke G, Jogi R, Torén K, Sigsgaard T, Schlünssen V, Olivieri M, Blanc PD, Watkins J, Bono R, Buist AS, Vermeulen R, Jarvis D, Zock JP. Occupational exposures and incidence of chronic bronchitis and related symptoms over two decades: the European Community Respiratory Health Survey. Occup Environ Med. 2019 04; 76(4):222-229.
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  18. Paulin LM, Smith BM, Koch A, Han M, Hoffman EA, Martinez C, Ejike C, Blanc PD, Rous J, Barr RG, Peters SP, Paine R, Pirozzi C, Cooper CB, Dransfield MT, Comellas AP, Kanner RE, Drummond MB, Putcha N, Hansel NN. Occupational Exposures and Computed Tomographic Imaging Characteristics in the SPIROMICS Cohort. Ann Am Thorac Soc. 2018 12; 15(12):1411-1419.
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  19. Gajic S, Callahan EC, Brown JK, Elicker B, Ley B, Blanc PD. Pulmonary toxicity associated with pomalidomide. Int J Tuberc Lung Dis. 2018 11 01; 22(11):1383-1386.
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  20. Torén K, Andersson M, Olin AC, Blanc PD, Järvholm B. Airflow limitation classified with the fixed ratio or the lower limit of normal and cause-specific mortality - A prospective study. Respir Med. 2018 11; 144:36-41.
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