Robert Blelloch, MD, PhD

Associate Professor, Department of Urology, UCSF
Peter R. Carroll, MD, Endowed Chair, UCSF

blellochr@stemcell.ucsf.edu

Phone: (415) 476-2838 (voice)
Box 0525, UCSF

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Education

Duke University, Durham, North Carolina, B.S., 5/1989, Zoology
Duke University, Durham, North Carolina, M.A.T., 5/1990, Biology
University of Wisconsin, Madison, Wisconsin, Ph.D., 5/1999, Cell & Molec Biology
University of Wisconsin, Madison, Wisconsin, M.D., 5/2001, Medicine

Professional Experience

• 7/01 - 7/02
  Resident, Pathology, Brigham and Women's Hospital
• 3/03 - 7/02
  Chief Resident, Pathology, Brigham and Women's Hospital
• 7/04 - 7/02
  Clinical Fellow, Harvard Medical School Joint Program of Transfusion Medicine
• 8/02 - 12/02
  Post-Doctoral Fellow, Whitehead Institute of Biomedical Research
• 12/05 - 7/10
  Assistant Professor, Institute for Regenerative Medicine and Comprehensive Cancer Center, Departments of Urology and Pathology, University of California, San Francisco
• 7/10 - present
  Associate Professor, UCSF
• 7/10 - present
  Chair, UCSF Biomedical Sciences Graduate Program Admissions Committee

Honors & Awards

• 2000-2001
  Rath Wisconsin Distinguished Graduate Fellow
• 2001
  GATE Pharmaceuticals Outstanding Medical Student Award
• 2001
  Alpha Omega Alpha (Medical Student Honor Society)
• 2001
  University of Wisconsin-Madison Commencement Student Speaker
• 2004
  Paul E. Strandjord Young Investigator Award with Distinction
• 2006-
  Peter Carroll Endowed Chair
• 2007-2011
  Pew Scholar
• 2009
  Kavli Fellow (National Academy of Sciences
• 2011
  International Society of Stem Cell Research Outstanding Young Investigator Award.

Selected Publications

1. Blelloch R, Gutkind JS. Epigenetics, noncoding RNAs, and cell signaling-crossroads in the regulation of cell fate decisions. Curr Opin Cell Biol. 2013 Apr; 25(2):149-51.
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2. Lamouille S, Subramanyam D, Blelloch R, Derynck R. Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. Curr Opin Cell Biol. 2013 Apr; 25(2):200-7.
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3. Cook MS, Blelloch R. Small RNAs in Germline Development. Curr Top Dev Biol. 2013; 102:159-205.
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4. Venere M, Han YG, Bell R, Song JS, Alvarez-Buylla A, Blelloch R. Sox1 marks an activated neural stem/progenitor cell in the hippocampus. Development. 2012 Nov; 139(21):3938-49.
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5. Hsu R, Schofield CM, Dela Cruz CG, Jones-Davis DM, Blelloch R, Ullian EM. Loss of microRNAs in pyramidal neurons leads to specific changes in inhibitory synaptic transmission in the prefrontal cortex. Mol Cell Neurosci. 2012 Jul; 50(3-4):283-92.
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6. Manoli DS, Subramanyam D, Carey C, Sudin E, Van Westerhuyzen JA, Bales KL, Blelloch R, Shah NM. Generation of induced pluripotent stem cells from the prairie vole. PLoS One. 2012; 7(5):e38119.
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7. Barad O, Mann M, Chapnik E, Shenoy A, Blelloch R, Barkai N, Hornstein E. Efficiency and specificity in microRNA biogenesis. Nat Struct Mol Biol. 2012 Jun; 19(6):650-2.
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8. Shenoy A, Blelloch R. microRNA induced transdifferentiation. F1000 Biol Rep. 2012; 4:3.
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9. Chapnik E, Sasson V, Blelloch R, Hornstein E. Dgcr8 controls neural crest cells survival in cardiovascular development. Dev Biol. 2012 Feb 1; 362(1):50-6.
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10. Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R, Ansel KM. MicroRNA-29 regulates T-box transcription factors and interferon-? production in helper T cells. Immunity. 2011 Aug 26; 35(2):169-81.
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11. Moltzahn F, Hunkapiller N, Mir AA, Imbar T, Blelloch R. High throughput microRNA profiling: optimized multiplex qRT-PCR at nanoliter scale on the fluidigm dynamic arrayTM IFCs. J Vis Exp. 2011; (54).
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12. Babiarz JE, Hsu R, Melton C, Thomas M, Ullian EM, Blelloch R. A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing. RNA. 2011 Aug; 17(8):1489-501.
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13. Subramanyam D, Blelloch R. From microRNAs to targets: pathway discovery in cell fate transitions. Curr Opin Genet Dev. 2011 Aug; 21(4):498-503.
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14. Suh N, Blelloch R. Small RNAs in early mammalian development: from gametes to gastrulation. Development. 2011 May; 138(9):1653-61.
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15. Subramanyam D, Lamouille S, Judson RL, Liu JY, Bucay N, Derynck R, Blelloch R. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat Biotechnol. 2011 May; 29(5):443-8.
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16. Schofield CM, Hsu R, Barker AJ, Gertz CC, Blelloch R, Ullian EM. Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex. Neural Dev. 2011; 6:11.
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17. Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M. Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 1; 25(7):755-66.
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18. Wang Y, Blelloch R. Cell cycle regulation by microRNAs in stem cells. Results Probl Cell Differ. 2011; 53:459-72.
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19. Moltzahn F, Olshen AB, Baehner L, Peek A, Fong L, Stöppler H, Simko J, Hilton JF, Carroll P, Blelloch R. Microfluidic-based multiplex qRT-PCR identifies diagnostic and prognostic microRNA signatures in the sera of prostate cancer patients. Cancer Res. 2011 Jan 15; 71(2):550-60.
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20. Elefanty AG, Blelloch R, Passegué E, Wernig M, Mummery CL. On the streets of San Francisco: highlights from the ISSCR Annual Meeting 2010. Cell Stem Cell. 2010 Oct 8; 7(4):443-50.
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