Robert Blelloch, MD, PhD


Associate Professor, Department of Urology, UCSF
Peter R. Carroll, MD, Endowed Chair, UCSF

Phone: (415) 476-2838 (voice)
Box 0525, UCSF

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Duke University, Durham, North Carolina, B.S., 5/1989, Zoology
Duke University, Durham, North Carolina, M.A.T., 5/1990, Biology
University of Wisconsin, Madison, Wisconsin, Ph.D., 5/1999, Cell & Molec Biology
University of Wisconsin, Madison, Wisconsin, M.D., 5/2001, Medicine

Professional Experience

  • 7/01 - 7/02
    Resident, Pathology, Brigham and Women's Hospital
  • 3/03 - 7/02
    Chief Resident, Pathology, Brigham and Women's Hospital
  • 7/04 - 7/02
    Clinical Fellow, Harvard Medical School Joint Program of Transfusion Medicine
  • 8/02 - 12/02
    Post-Doctoral Fellow, Whitehead Institute of Biomedical Research
  • 12/05 - 7/10
    Assistant Professor, Institute for Regenerative Medicine and Comprehensive Cancer Center, Departments of Urology and Pathology, University of California, San Francisco
  • 7/10 - present
    Associate Professor, UCSF
  • 7/10 - present
    Chair, UCSF Biomedical Sciences Graduate Program Admissions Committee

Honors & Awards

  • 2000-2001
    Rath Wisconsin Distinguished Graduate Fellow
  • 2001
    GATE Pharmaceuticals Outstanding Medical Student Award
  • 2001
    Alpha Omega Alpha (Medical Student Honor Society)
  • 2001
    University of Wisconsin-Madison Commencement Student Speaker
  • 2004
    Paul E. Strandjord Young Investigator Award with Distinction
  • 2006-
    Peter Carroll Endowed Chair
  • 2007-2011
    Pew Scholar
  • 2009
    Kavli Fellow (National Academy of Sciences
  • 2011
    International Society of Stem Cell Research Outstanding Young Investigator Award.

Selected Publications

  1. Ye J, Blelloch R. Regulation of pluripotency by RNA binding proteins. Cell Stem Cell. 2014 Sep 4; 15(3):271-80.
    View on PubMed
  2. Shenoy A, Blelloch RH. Regulation of microRNA function in somatic stem cell proliferation and differentiation. Nat Rev Mol Cell Biol. 2014 Sep; 15(9):565-76.
    View on PubMed
  3. Wang SY, Shiboski S, Belair CD, Cooperberg MR, Simko JP, Stoppler H, Cowan J, Carroll PR, Blelloch R. miR-19, miR-345, miR-519c-5p Serum Levels Predict Adverse Pathology in Prostate Cancer Patients Eligible for Active Surveillance. PLoS One. 2014; 9(6):e98597.
    View on PubMed
  4. Parchem RJ, Ye J, Judson RL, Larussa MF, Krishnakumar R, Blelloch A, Oldham MC, Blelloch R. Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming. Cell Stem Cell. 2014 May 1; 14(5):617-31.
    View on PubMed
  5. Judson RL, Greve TS, Parchem RJ, Blelloch R. MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells. Nat Struct Mol Biol. 2013 Oct; 20(10):1227-35.
    View on PubMed
  6. Krishnakumar R, Blelloch RH. Epigenetics of cellular reprogramming. Curr Opin Genet Dev. 2013 Oct; 23(5):548-55.
    View on PubMed
  7. Greve TS, Judson RL, Blelloch R. microRNA control of mouse and human pluripotent stem cell behavior. Annu Rev Cell Dev Biol. 2013; 29:213-39.
    View on PubMed
  8. Wang Y, Melton C, Li YP, Shenoy A, Zhang XX, Subramanyam D, Blelloch R. miR-294/miR-302 promotes proliferation, suppresses G1-S restriction point, and inhibits ESC differentiation through separable mechanisms. Cell Rep. 2013 Jul 11; 4(1):99-109.
    View on PubMed
  9. Jeker LT, Zhou X, Blelloch R, Bluestone JA. DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability. PLoS One. 2013; 8(5):e66282.
    View on PubMed
  10. Blelloch R, Gutkind JS. Epigenetics, noncoding RNAs, and cell signaling--crossroads in the regulation of cell fate decisions. Curr Opin Cell Biol. 2013 Apr; 25(2):149-51.
    View on PubMed
  11. Lamouille S, Subramanyam D, Blelloch R, Derynck R. Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. Curr Opin Cell Biol. 2013 Apr; 25(2):200-7.
    View on PubMed
  12. Cook MS, Blelloch R. Small RNAs in germline development. Curr Top Dev Biol. 2013; 102:159-205.
    View on PubMed
  13. Venere M, Han YG, Bell R, Song JS, Alvarez-Buylla A, Blelloch R. Sox1 marks an activated neural stem/progenitor cell in the hippocampus. Development. 2012 Nov; 139(21):3938-49.
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  14. Hsu R, Schofield CM, Dela Cruz CG, Jones-Davis DM, Blelloch R, Ullian EM. Loss of microRNAs in pyramidal neurons leads to specific changes in inhibitory synaptic transmission in the prefrontal cortex. Mol Cell Neurosci. 2012 Jul; 50(3-4):283-92.
    View on PubMed
  15. Manoli DS, Subramanyam D, Carey C, Sudin E, Van Westerhuyzen JA, Bales KL, Blelloch R, Shah NM. Generation of induced pluripotent stem cells from the prairie vole. PLoS One. 2012; 7(5):e38119.
    View on PubMed
  16. Barad O, Mann M, Chapnik E, Shenoy A, Blelloch R, Barkai N, Hornstein E. Efficiency and specificity in microRNA biogenesis. Nat Struct Mol Biol. 2012 Jun; 19(6):650-2.
    View on PubMed
  17. Shenoy A, Blelloch R. microRNA induced transdifferentiation. F1000 Biol Rep. 2012; 4:3.
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  18. Chapnik E, Sasson V, Blelloch R, Hornstein E. Dgcr8 controls neural crest cells survival in cardiovascular development. Dev Biol. 2012 Feb 1; 362(1):50-6.
    View on PubMed
  19. Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R, Ansel KM. MicroRNA-29 regulates T-box transcription factors and interferon-? production in helper T cells. Immunity. 2011 Aug 26; 35(2):169-81.
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  20. Moltzahn F, Hunkapiller N, Mir AA, Imbar T, Blelloch R. High throughput microRNA profiling: optimized multiplex qRT-PCR at nanoliter scale on the fluidigm dynamic arrayTM IFCs. J Vis Exp. 2011; (54).
    View on PubMed

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