Robert Blelloch, MD, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Robert Blelloch, MD, PhD

Associate Professor, Department of Urology, UCSF
Peter R. Carroll, MD, Endowed Chair, UCSF

blellochr@stemcell.ucsf.edu

Phone: (415) 476-2838 (voice)
Box 0525, UCSF

View on UCSF Profiles

Cancer Center Membership

Program Member ยป Prostate Cancer

Education

Duke University, Durham, North Carolina, B.S., 5/1989, Zoology
Duke University, Durham, North Carolina, M.A.T., 5/1990, Biology
University of Wisconsin, Madison, Wisconsin, Ph.D., 5/1999, Cell & Molec Biology
University of Wisconsin, Madison, Wisconsin, M.D., 5/2001, Medicine


Professional Experience

  • 7/01 - 7/02
    Resident, Pathology, Brigham and Women's Hospital
  • 3/03 - 7/02
    Chief Resident, Pathology, Brigham and Women's Hospital
  • 7/04 - 7/02
    Clinical Fellow, Harvard Medical School Joint Program of Transfusion Medicine
  • 8/02 - 12/02
    Post-Doctoral Fellow, Whitehead Institute of Biomedical Research
  • 12/05 - 7/10
    Assistant Professor, Institute for Regenerative Medicine and Comprehensive Cancer Center, Departments of Urology and Pathology, University of California, San Francisco
  • 7/10 - present
    Associate Professor, UCSF
  • 7/10 - present
    Chair, UCSF Biomedical Sciences Graduate Program Admissions Committee

Honors & Awards

  • 2000-2001
    Rath Wisconsin Distinguished Graduate Fellow
  • 2001
    GATE Pharmaceuticals Outstanding Medical Student Award
  • 2001
    Alpha Omega Alpha (Medical Student Honor Society)
  • 2001
    University of Wisconsin-Madison Commencement Student Speaker
  • 2004
    Paul E. Strandjord Young Investigator Award with Distinction
  • 2006-
    Peter Carroll Endowed Chair
  • 2007-2011
    Pew Scholar
  • 2009
    Kavli Fellow (National Academy of Sciences
  • 2011
    International Society of Stem Cell Research Outstanding Young Investigator Award.

Selected Publications

  1. Russ HA, Parent AV, Ringler JJ, Hennings TG, Nair GG, Shveygert M, Guo T, Puri S, Haataja L, Cirulli V, Blelloch R, Szot GL, Arvan P, Hebrok M. Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro. EMBO J. 2015 Jul 2; 34(13):1759-72.
    View on PubMed
  2. Huskey NE, Guo T, Evason KJ, Momcilovic O, Pardo D, Creasman KJ, Judson RL, Blelloch R, Oakes SA, Hebrok M, Goga A. CDK1 Inhibition Targets the p53-NOXA-MCL1 Axis, Selectively Kills Embryonic Stem Cells, and Prevents Teratoma Formation. Stem Cell Reports. 2015 Mar 10; 4(3):374-89.
    View on PubMed
  3. Shenoy A, Danial M, Blelloch RH. Let-7 and miR-125 cooperate to prime progenitors for astrogliogenesis. EMBO J. 2015 May 5; 34(9):1180-94.
    View on PubMed
  4. Kobayashi T, Papaioannou G, Mirzamohammadi F, Kozhemyakina E, Zhang M, Blelloch R, Chong MW. Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage. Osteoarthritis Cartilage. 2015 Jul; 23(7):1214-20.
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  5. Guo WT, Wang XW, Yan YL, Li YP, Yin X, Zhang Q, Melton C, Shenoy A, Reyes NA, Oakes SA, Blelloch R, Wang Y. Suppression of epithelial-mesenchymal transition and apoptotic pathways by miR-294/302 family synergistically blocks let-7-induced silencing of self-renewal in embryonic stem cells. Cell Death Differ. 2015 Jul; 22(7):1158-69.
    View on PubMed
  6. Ye J, Blelloch R. Regulation of pluripotency by RNA binding proteins. Cell Stem Cell. 2014 Sep 4; 15(3):271-80.
    View on PubMed
  7. Shenoy A, Blelloch RH. Regulation of microRNA function in somatic stem cell proliferation and differentiation. Nat Rev Mol Cell Biol. 2014 Sep; 15(9):565-76.
    View on PubMed
  8. Wang SY, Shiboski S, Belair CD, Cooperberg MR, Simko JP, Stoppler H, Cowan J, Carroll PR, Blelloch R. miR-19, miR-345, miR-519c-5p serum levels predict adverse pathology in prostate cancer patients eligible for active surveillance. PLoS One. 2014; 9(6):e98597.
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  9. Parchem RJ, Ye J, Judson RL, LaRussa MF, Krishnakumar R, Blelloch A, Oldham MC, Blelloch R. Two miRNA clusters reveal alternative paths in late-stage reprogramming. Cell Stem Cell. 2014 May 1; 14(5):617-31.
    View on PubMed
  10. Judson RL, Greve TS, Parchem RJ, Blelloch R. MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells. Nat Struct Mol Biol. 2013 Oct; 20(10):1227-35.
    View on PubMed
  11. Krishnakumar R, Blelloch RH. Epigenetics of cellular reprogramming. Curr Opin Genet Dev. 2013 Oct; 23(5):548-55.
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  12. Greve TS, Judson RL, Blelloch R. microRNA control of mouse and human pluripotent stem cell behavior. Annu Rev Cell Dev Biol. 2013; 29:213-39.
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  13. Wang Y, Melton C, Li YP, Shenoy A, Zhang XX, Subramanyam D, Blelloch R. miR-294/miR-302 promotes proliferation, suppresses G1-S restriction point, and inhibits ESC differentiation through separable mechanisms. Cell Rep. 2013 Jul 11; 4(1):99-109.
    View on PubMed
  14. Jeker LT, Zhou X, Blelloch R, Bluestone JA. DGCR8-mediated production of canonical microRNAs is critical for regulatory T cell function and stability. PLoS One. 2013; 8(5):e66282.
    View on PubMed
  15. Blelloch R, Gutkind JS. Epigenetics, noncoding RNAs, and cell signaling--crossroads in the regulation of cell fate decisions. Curr Opin Cell Biol. 2013 Apr; 25(2):149-51.
    View on PubMed
  16. Lamouille S, Subramanyam D, Blelloch R, Derynck R. Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs. Curr Opin Cell Biol. 2013 Apr; 25(2):200-7.
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  17. Cook MS, Blelloch R. Small RNAs in germline development. Curr Top Dev Biol. 2013; 102:159-205.
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  18. Venere M, Han YG, Bell R, Song JS, Alvarez-Buylla A, Blelloch R. Sox1 marks an activated neural stem/progenitor cell in the hippocampus. Development. 2012 Nov; 139(21):3938-49.
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  19. Hsu R, Schofield CM, Dela Cruz CG, Jones-Davis DM, Blelloch R, Ullian EM. Loss of microRNAs in pyramidal neurons leads to specific changes in inhibitory synaptic transmission in the prefrontal cortex. Mol Cell Neurosci. 2012 Jul; 50(3-4):283-92.
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  20. Manoli DS, Subramanyam D, Carey C, Sudin E, Van Westerhuyzen JA, Bales KL, Blelloch R, Shah NM. Generation of induced pluripotent stem cells from the prairie vole. PLoS One. 2012; 7(5):e38119.
    View on PubMed

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