Research Summary

Dr. Dean Chou is Professor Emeritus in the Department of Neurosurgery at UCSF.

Education

University of California Berkeley, 1991, B.A., Biochemistry
University of California, San Francisco, 1996, M.D., Medicine
The Johns Hopkins Hospital, 1996-1997, Intern, General Surgery
The Johns Hopkins Hospital, 1997-2002, Resident, Neurosurgery
The Johns Hopkins Hospital, Assistant Chief of Service, 2002-2003, Neurosurgery
Barrow Neurological Institute, Spine Fellow, 2003-2004, Spine surgery

Honors & Awards

  • 1990
    UC Berkeley Honor Students Society
  • 1990
    American Heart Association Research Fellowship
  • 1991
    Golden Key National Honor Society
  • 1992
    UCSF School of Medicine Dean's Summer Research Fellowship
  • 1993
    UCSF Travel Award to Western Student Medical Research Committee Meeting in Carmel, CA
  • 1993
    American Federation for Clinical Research Award for Excellence in Research
  • 1994
    Howard Hughes Medical Institute Research Training Fellowship
  • 1995
    Lucien J. Rubinstein Award for Best Paper in Neuro-Oncology, American Association of Neuropathologists Annual Meeting
  • 2000
    AANS Neurosurgery Research and Education Foundation (NREF) Grant
  • 2004
    Cover Article, Journal of Neurosurgery: Spine
  • 2007
    Who's Who in American Teachers and Educators
  • 2007
    Who's Who in Science and Engineering
  • 2007
    Harold Rosegay Neurosurgery Resident Teaching Award
  • 2009
    Best Doctors in America
  • 2009
    Cover Article, Journal of Neurosurgery: Spine
  • 2010
    Outcomes Committee Award, AANS/CNS Joint Section on Disorders of the Spine and Peripheral Nerves
  • 2010
    Cover Article, Journal of Neurosurgery: Spine

Selected Publications

  1. Passias PG, Pierce KE, Williamson TK, Lebovic J, Schoenfeld AJ, Lafage R, Lafage V, Gum JL, Eastlack R, Kim HJ, Klineberg EO, Daniels AH, Protopsaltis TS, Mundis GM, Scheer JK, Park P, Chou D, Line B, Hart RA, Burton DC, Bess S, Schwab FJ, Shaffrey CI, Smith JS, Ames CP, International Spine Study Group. Patient-specific Cervical Deformity Corrections With Consideration of Associated Risk: Establishment of Risk Benefit Thresholds for Invasiveness Based on Deformity and Frailty Severity. Clin Spine Surg. 2023 Oct 06.  View on PubMed
  2. Izima C, Sampath SG, Tang AJ, Ambati VS, Chou D, Chan AK. Systematic review and meta-analysis of topical tranexamic acid in spine surgery. Neurosurg Focus. 2023 Oct; 55(4):E18.  View on PubMed
  3. Ambati VS, Macki M, Chan AK, Michalopoulos GD, Le VP, Jamieson AB, Chou D, Shaffrey CI, Gottfried ON, Bisson EF, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialán LM, Turner JD, Sherrod BA, Haid RW, Bydon M, Mummaneni PV. Three-level ACDF versus 3-level laminectomy and fusion: are there differences in outcomes? An analysis of the Quality Outcomes Database cervical spondylotic myelopathy cohort. Neurosurg Focus. 2023 Sep; 55(3):E2.  View on PubMed
  4. Yang E, Mummaneni PV, Chou D, Bydon M, Bisson EF, Shaffrey CI, Gottfried ON, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya CD, Shaffrey ME, Buchholz AL, Tumialán LM, Turner JD, Michalopoulos GD, Sherrod BA, Agarwal N, Haid RW, Chan AK. Cervical laminoplasty versus laminectomy and posterior cervical fusion for cervical myelopathy: propensity-matched analysis of 24-month outcomes from the Quality Outcomes Database. J Neurosurg Spine. 2023 Aug 11; 1-11.  View on PubMed
  5. Liu J, Xie R, Chin CT, Rajagopalan P, Duan PG, Li B, Burch S, Berven SH, Mummaneni PV, Chou D. Comparison of Lumbosacral Fusion Grade in Patients after Transforaminal and Anterior Lumbar Interbody Fusion with Minimum 2-Year Follow-Up. Orthop Surg. 2023 Sep; 15(9):2334-2341.  View on PubMed
  6. CreveCoeur TS, Sperring CP, DiGiorgio AM, Chou D, Chan AK. Antepsoas Approaches to the Lumbar Spine. Neurosurg Clin N Am. 2023 Oct; 34(4):619-632.  View on PubMed
  7. Campbell LJ, Mummaneni PV, Letchuman V, Langnas E, Agarwal N, Guan LS, Croci R, Vargas E, Reisner L, Bickler P, Chou D, Chang E, Guan Z. Mismatched opioid prescription in patients discharged after neurological surgeries: a retrospective cohort study. Pain. 2023 Jun 15.  View on PubMed
  8. Shahrestani S, Chan AK, Bisson EF, Bydon M, Glassman SD, Foley KT, Shaffrey CI, Potts EA, Shaffrey ME, Coric D, Knightly JJ, Park P, Wang MY, Fu KM, Slotkin JR, Asher AL, Virk MS, Michalopoulos GD, Guan J, Haid RW, Agarwal N, Chou D, Mummaneni PV. Developing nonlinear k-nearest neighbors classification algorithms to identify patients at high risk of increased length of hospital stay following spine surgery. Neurosurg Focus. 2023 06; 54(6):E7.  View on PubMed
  9. Park C, Mummaneni PV, Gottfried ON, Shaffrey CI, Tang AJ, Bisson EF, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya C, Shaffrey ME, Buchholz AL, Tumialán LM, Turner JD, Sherrod BA, Agarwal N, Chou D, Haid RW, Bydon M, Chan AK. Which supervised machine learning algorithm can best predict achievement of minimum clinically important difference in neck pain after surgery in patients with cervical myelopathy? A QOD study. Neurosurg Focus. 2023 06; 54(6):E5.  View on PubMed
  10. Semonche A, Scheer JK, Shah VN, Fung M, Tan LA, Chou D, Mummaneni PV, Berven SH, Ames CP, Deviren V, Theologis AA, Clark AJ. Duration of neurological deficit and outcomes in the surgical treatment of spinal coccidioidomycosis. J Neurosurg Spine. 2023 09 01; 39(3):419-426.  View on PubMed
  11. Passias PG, Williamson TK, Joujon-Roche R, Krol O, Tretiakov P, Imbo B, Schoenfeld AJ, Owusu-Sarpong S, Lebovic J, Mir J, Dave P, McFarland K, Vira S, Diebo BG, Park P, Chou D, Smith JS, Lafage R, Lafage V. The Impact of Lumbopelvic Realignment versus Prevention Strategies at the Upper-Instrumented Vertebra on Rates of Junctional Failure following Adult Spinal Deformity Surgery. Spine (Phila Pa 1976). 2023 May 26.  View on PubMed
  12. Asher AL, Haid RW, Stroink AR, Michalopoulos GD, Alexander AY, Zeitouni D, Chan AK, Virk MS, Glassman SD, Foley KT, Slotkin JR, Potts EA, Shaffrey ME, Shaffrey CI, Park P, Upadhyaya C, Coric D, Tumialán LM, Chou D, Fu KG, Knightly JJ, Orrico KO, Wang MY, Bisson EF, Mummaneni PV, Bydon M. Research using the Quality Outcomes Database: accomplishments and future steps toward higher-quality real-world evidence. J Neurosurg. 2023 May 19; 1-19.  View on PubMed
  13. Vargas E, Shabani S, Mummaneni PV, Park C, Rechav Ben-Natan A, Rivera JJ, Huang J, Berven S, Braunstein S, Chou D. Does surgery for metastatic spinal tumors improve functional outcomes in patients without spinal cord compression but with potentially unstable spines (SINS 7-12)? J Neurosurg Spine. 2023 08 01; 39(2):287-294.  View on PubMed
  14. Farber SH, Walker CT, Zhou JJ, Godzik J, Gandhi SV, de Andrada Pereira B, Koffie RM, Xu DS, Sciubba DM, Shin JH, Steinmetz MP, Wang MY, Shaffrey CI, Kanter AS, Yen CP, Chou D, Blaskiewicz DJ, Phillips FM, Park P, Mummaneni PV, Fessler RD, Härtl R, Glassman SD, Koski T, Deviren V, Taylor WR, Kakarla UK, Turner JD, Uribe JS. Reliability of a Novel Classification System for Thoracic Disc Herniations. Spine (Phila Pa 1976). 2023 May 01.  View on PubMed
  15. Neira JA, Chou D. Commentary: Augmented Reality-Assisted Resection of a Large Presacral Ganglioneuroma: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2023 07 01; 25(1):e60-e61.  View on PubMed
  16. Passias PG, Tretiakov PS, Nunley PD, Wang MY, Park P, Kanter AS, Okonkwo DO, Eastlack RK, Mundis GM, Chou D, Agarwal N, Fessler RG, Uribe JS, Anand N, Than KD, Brusko G, Fu KM, Turner JD, Le VP, Line BG, Ames CP, Smith JS, Shaffrey CI, Hart RA, Burton D, Lafage R, Lafage V, Schwab F, Bess S, Mummaneni PV. Incremental benefits of circumferential minimally invasive surgery for increasingly frail patients with adult spinal deformity. J Neurosurg Spine. 2023 08 01; 39(2):168-174.  View on PubMed
  17. Passias PG, Joujon-Roche R, Mir JM, Williamson TK, Tretiakov PS, Imbo B, Krol O, Passfall L, Ahmad S, Lebovic J, Owusu-Sarpong S, Lanre-Amos T, Protopsaltis T, Lafage R, Lafage V, Park P, Chou D, Mummaneni PV, Fu KG, Than KD, Smith JS, Janjua MB, Schoenfeld AJ, Diebo BG, Vira S. Natural history of adult spinal deformity: how do patients with suboptimal surgical outcomes fare relative to nonoperative counterparts? J Neurosurg Spine. 2023 Jul 01; 39(1):92-100.  View on PubMed
  18. Chan AK, Shaffrey CI, Park C, Gottfried ON, Than KD, Bisson EF, Bydon M, Asher AL, Coric D, Potts EA, Foley KT, Wang MY, Fu KM, Virk MS, Knightly JJ, Meyer S, Park P, Upadhyaya CD, Shaffrey ME, Buchholz AL, Tumialán LM, Turner JD, Michalopoulos GD, Sherrod BA, Agarwal N, Chou D, Haid RW, Mummaneni PV. Do comorbid self-reported depression and anxiety influence outcomes following surgery for cervical spondylotic myelopathy? J Neurosurg Spine. 2023 Jul 01; 39(1):11-27.  View on PubMed
  19. Passias PG, Williamson TK, Krol O, Joujon-Roche R, Imbo B, Tretiakov P, Ahmad S, Bennett-Caso C, Lebovic J, Owusu-Sarpong S, Park P, Chou D, Vira S, Diebo BG, Schoenfeld AJ. Patient-Centered Outcomes Following Prone Lateral Single-Position Approach to Same-Day Circumferential Spine Surgery. Spine (Phila Pa 1976). 2023 Mar 24.  View on PubMed
  20. Bharadwaj UU, Christine M, Li S, Chou D, Pedoia V, Link TM, Chin CT, Majumdar S. Deep learning for automated, interpretable classification of lumbar spinal stenosis and facet arthropathy from axial MRI. Eur Radiol. 2023 May; 33(5):3435-3443.  View on PubMed

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