University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Dean Chou, MD

Dean Chou, MD

Associate Professor, Department of Neurological Surgery; Associate Director of Spinal Tumor Surgery, UCSF Spine Center

Research Summary

Dr. Dean Chou specializes in the treatment of complex and difficult spinal disorders. He treats such disorders as adult scoliosis, spinal deformities, flat back syndrome, kyphosis, kyphoscoliosis, spinal tumors, primary bony tumors of the spinal column, and metastatic disease to the spine. He is an expert in minimally invasive applications to such complex spinal disorders, and he has had multiple peer-reviewed papers published, describing his techniques. Moreover, he is an expert in traditional, open surgery for such complex procedures as en bloc spondylectomy and sacral resections for tumors, and osteotomies for adult scoliosis and adult deformity. His research goal is to try to accomplish the same goals of open surgery with minimally invasive techniques, which hopefully can lead to less morbidity and better outcomes for patients.

After medical school at UCSF, Dr. Chou completed his residency at The Johns Hopkins Hospital and then undertook a fellowship in complex spinal surgery at The Barrow Neurological Institute. He is board certified by the American Board of Neurological Surgery and has been elected by his peers for the past 8 consecutive years to the organization, “Best Doctors in America.”

In addition to having published as either first or senior author in SPINE, Journal of Neurosurgery: Spine, and Neurosurgery, his publications have been featured 5 times as the cover article of the Journal of Neurosurgery: Spine.

Dr. Chou is on the Advisory Board of the journal, SPINE, the Editorial Board of The Global Spine Journal, and on the Editorial Board for the journal, Neurosurgery. He has served for many years on the Scientific Program Committee for the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves, as an abstract reviewer for such society meetings as the North American Spine Society (NASS) and the Congress of Neurological Surgeons, and as faculty member for The American Association of Neurological Surgeons, The North American Spine Society, The Lumbar Spine Research Society, and the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves.

Education

University of California Berkeley, 1991, B.A., Biochemistry
University of California, San Francisco, 1996, M.D., Medicine
The Johns Hopkins Hospital, 1996-1997, Intern, General Surgery
The Johns Hopkins Hospital, 1997-2002, Resident, Neurosurgery
The Johns Hopkins Hospital, Assistant Chief of Service, 2002-2003, Neurosurgery
Barrow Neurological Institute, Spine Fellow, 2003-2004, Spine surgery


Professional Experience

  • 2002-2003
    Instructor in Neurosurgery, The Johns Hopkins Hospital
  • 2003-2004
    Staff Neurosurgeon/Spine Fellow, St. Joseph's Hospital, Phoenix, AZ
  • 2004-2010
    Assistant Clinical Professor, University of California, San Francisco
  • 2007-present
    Associate Director of Spinal Tumor Surgery
  • 2010-present
    Associate Professor of Clinical Neurosurgery, University of California, San Francisco

Honors & Awards

  • 1990
    UC Berkeley Honor Students Society
  • 1990
    American Heart Association Research Fellowship
  • 1991
    Golden Key National Honor Society
  • 1992
    UCSF School of Medicine Dean's Summer Research Fellowship
  • 1993
    UCSF Travel Award to Western Student Medical Research Committee Meeting in Carmel, CA
  • 1993
    American Federation for Clinical Research Award for Excellence in Research
  • 1994
    Howard Hughes Medical Institute Research Training Fellowship
  • 1995
    Lucien J. Rubinstein Award for Best Paper in Neuro-Oncology, American Association of Neuropathologists Annual Meeting
  • 2000
    AANS Neurosurgery Research and Education Foundation (NREF) Grant
  • 2004
    Cover Article, Journal of Neurosurgery: Spine
  • 2007
    Who's Who in American Teachers and Educators
  • 2007
    Who's Who in Science and Engineering
  • 2007
    Harold Rosegay Neurosurgery Resident Teaching Award
  • 2009
    Best Doctors in America
  • 2009
    Cover Article, Journal of Neurosurgery: Spine
  • 2010
    Outcomes Committee Award, AANS/CNS Joint Section on Disorders of the Spine and Peripheral Nerves
  • 2010
    Cover Article, Journal of Neurosurgery: Spine

Selected Publications

  1. Lau D, Winkler EA, Than KD, Chou D, Mummaneni PV. Laminoplasty versus laminectomy with posterior spinal fusion for multilevel cervical spondylotic myelopathy: influence of cervical alignment on outcomes. J Neurosurg Spine. 2017 Sep 01; 1-10.
    View on PubMed
  2. Safaee MM, Winkler EA, Chou D. Mini-open spinal column shortening for the treatment of adult tethered cord syndrome. J Clin Neurosci. 2017 Oct; 44:315-319.
    View on PubMed
  3. DiGiorgio AM, Edwards CS, Virk MS, Mummaneni PV, Chou D. Stereotactic navigation for the prepsoas oblique lateral lumbar interbody fusion: technical note and case series. Neurosurg Focus. 2017 Aug; 43(2):E14.
    View on PubMed
  4. Leung JM, Sands LP, Chen N, Ames C, Berven S, Bozic K, Burch S, Chou D, Covinsky K, Deviren V, Kinjo S, Kramer JH, Ries M, Tay B, Vail T, Weinstein P, Chang S, Meckler G, Newman S, Tsai T, Voss V, Youngblom E. Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. Anesthesiology. 2017 Jul 20.
    View on PubMed
  5. Zhang YH, Shen L, Shao J, Chou D, Song J, Zhang J. Structural allograft versus autograft for instrumented atlantoaxial fusions in pediatric patients: radiological and clinical outcomes in a series of 32 patients. World Neurosurg. 2017 Jun 14.
    View on PubMed
  6. Oya J, Burke JF, Vogel T, Tay B, Chou D, Mummaneni P. The accuracy of multimodality intraoperative neuromonitoring to predict postoperative neurological deficits following cervical laminoplasty. World Neurosurg. 2017 Jun 12.
    View on PubMed
  7. Tabaraee E, Mummaneni P, Abdul-Jabbar A, Shearer D, Roy E, Amin B, Ames C, Burch S, Deviren V, Berven S, Hu S, Chou D, Tay BK. A Comparison of Implants Used in Open-Door Laminoplasty: Structural Rib Allografts Versus Metallic Miniplates. Clin Spine Surg. 2017 Jun; 30(5):E523-E529.
    View on PubMed
  8. Clarke MJ, Molina CA, Fourney DR, Fisher CG, Gokaslan ZL, Schmidt MH, Rhines LD, Fehlings MG, Laufer I, Patel SR, Rampersaud YR, Reynolds J, Chou D, Bettegowda C, Mendel E, Weber MH, Sciubba DM. Systematic Review of the Outcomes of Surgical Treatment of Prostate Metastases to the Spine. Global Spine J. 2017 Aug; 7(5):460-468.
    View on PubMed
  9. Kumar A, Weber MH, Gokaslan Z, Wolinsky JP, Schmidt M, Rhines L, Fehlings MG, Laufer I, Sciubba DM, Clarke MJ, Sundaresan N, Verlaan JJ, Sahgal A, Chou D, Fisher CG. Metastatic Spinal Cord Compression and Steroid Treatment: A Systematic Review. Clin Spine Surg. 2017 May; 30(4):156-163.
    View on PubMed
  10. Shankar GM, Clarke MJ, Ailon T, Rhines LD, Patel SR, Sahgal A, Laufer I, Chou D, Bilsky MH, Sciubba DM, Fehlings MG, Fisher CG, Gokaslan ZL, Shin JH. The role of revision surgery and adjuvant therapy following subtotal resection of osteosarcoma of the spine: a systematic review with meta-analysis. J Neurosurg Spine. 2017 Jul; 27(1):97-104.
    View on PubMed
  11. Lau D, Chou D. Minimally invasive instrumentation without fusion during posterior thoracic corpectomies: a comparison of percutaneously instrumented nonfused segments with open instrumented fused segments. J Neurosurg Spine. 2017 Jul; 27(1):35-41.
    View on PubMed
  12. Jahangiri A, Chin AT, Wagner JR, Kunwar S, Ames C, Chou D, Barani I, Parsa AT, McDermott MW, Benet A, El-Sayed IH, Aghi MK. In Reply: Factors Predicting Recurrence After Resection of Clival Chordoma Using Variable Surgical Approaches and Radiation Modalities. Neurosurgery. 2017 Apr 04.
    View on PubMed
  13. Thompson SE, Smith ZA, Hsu WK, Nassr A, Mroz TE, Fish DE, Wang JC, Fehlings MG, Tannoury CA, Tannoury T, Tortolani PJ, Traynelis VC, Gokaslan Z, Hilibrand AS, Isaacs RE, Mummaneni PV, Chou D, Qureshi SA, Cho SK, Baird EO, Sasso RC, Arnold PM, Buser Z, Bydon M, Clarke MJ, De Giacomo AF, Derakhshan A, Jobse B, Lord EL, Lubelski D, Massicotte EM, Steinmetz MP, Smith GA, Pace J, Corriveau M, Lee S, Cha PI, Chatterjee D, Gee EL, Mayer EN, McBride OJ, Roe AK, Yanez MY, Stroh DA, Than KD, Riew KD. C5 Palsy After Cervical Spine Surgery: A Multicenter Retrospective Review of 59 Cases. Global Spine J. 2017 Apr; 7(1 Suppl):64S-70S.
    View on PubMed
  14. O'Neill KR, Fehlings MG, Mroz TE, Smith ZA, Hsu WK, Kanter AS, Steinmetz MP, Arnold PM, Mummaneni PV, Chou D, Nassr A, Qureshi SA, Cho SK, Baird EO, Smith JS, Shaffrey C, Tannoury CA, Tannoury T, Gokaslan ZL, Gum JL, Hart RA, Isaacs RE, Sasso RC, Bumpass DB, Bydon M, Corriveau M, De Giacomo AF, Derakhshan A, Jobse BC, Lubelski D, Lee S, Massicotte EM, Pace JR, Smith GA, Than KD, Riew KD. A Multicenter Study of the Presentation, Treatment, and Outcomes of Cervical Dural Tears. Global Spine J. 2017 Apr; 7(1 Suppl):58S-63S.
    View on PubMed
  15. Ailon T, Smith JS, Nassr A, Smith ZA, Hsu WK, Fehlings MG, Fish DE, Wang JC, Hilibrand AS, Mummaneni PV, Chou D, Sasso RC, Traynelis VC, Arnold PM, Mroz TE, Buser Z, Lord EL, Massicotte EM, Sebastian AS, Than KD, Steinmetz MP, Smith GA, Pace J, Corriveau M, Lee S, Riew KD, Shaffrey C. Rare Complications of Cervical Spine Surgery: Pseudomeningocoele. Global Spine J. 2017 Apr; 7(1 Suppl):109S-114S.
    View on PubMed
  16. Uribe JS, Beckman J, Mummaneni PV, Okonkwo D, Nunley P, Wang MY, Mundis GM, Park P, Eastlack R, Anand N, Kanter A, Lamarca F, Fessler R, Shaffrey CI, Lafage V, Chou D, Deviren V. Does MIS Surgery Allow for Shorter Constructs in the Surgical Treatment of Adult Spinal Deformity? Neurosurgery. 2017 03 01; 80(3):489-497.
    View on PubMed
  17. Bettegowda C, Yip S, Lo SL, Fisher CG, Boriani S, Rhines LD, Wang JY, Lazary A, Gambarotti M, Wang WL, Luzzati A, Dekutoski MB, Bilsky MH, Chou D, Fehlings MG, McCarthy EF, Quraishi NA, Reynolds JJ, Sciubba DM, Williams RP, Wolinsky JP, Zadnik PL, Zhang M, Germscheid NM, Kalampoki V, Varga PP, Gokaslan ZL. Spinal column chordoma: prognostic significance of clinical variables and T (brachyury) gene SNP rs2305089 for local recurrence and overall survival. Neuro Oncol. 2017 Mar 01; 19(3):405-413.
    View on PubMed
  18. Charest-Morin R, Fisher CG, Varga PP, Gokaslan ZL, Rhines LD, Reynolds JJ, Dekutoski MB, Quraishi NA, Bilsky MH, Fehlings MG, Chou D, Germscheid NM, Luzzati A, Boriani S. En bloc resection versus intralesional surgery in the treatment of giant cell tumor of the spine. Spine (Phila Pa 1976). 2017 Jan 31.
    View on PubMed
  19. Zygourakis CC, Sizdahkhani S, Keefe M, Lee J, Chou D, Mummaneni PV, Ames CP. Comparison of Patient Outcomes and Cost of Overlapping Versus Nonoverlapping Spine Surgery. World Neurosurg. 2017 Apr; 100:658-664.e8.
    View on PubMed
  20. Chou D, Bilsky MH, Luzzati A, Fisher CG, Gokaslan ZL, Rhines LD, Dekutoski MB, Fehlings MG, Ghag R, Varga P, Boriani S, Germscheid NM, Reynolds JJ. Malignant peripheral nerve sheath tumors of the spine: results of surgical management from a multicenter study. J Neurosurg Spine. 2016 Nov 11; 1-8.
    View on PubMed

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