Ivan El-Sayed, MD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Ivan El-Sayed, MD

Professor, Department of Otolaryngology - Head and Neck Surgery, UCSF

Phone: (415) 353-2757 (appts)
Box 0342, UCSF
San Francisco, CA 94143-0342

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Cancer Center Membership

Associate Member » Non-aligned

Research Summary

Ivan H. El-Sayed, MD, is Professor of Clinical Otolaryngology and the Director of the Otolaryngology Minimally Invasive Skill Base Surgery program and center in the Department of Otolaryngology – Head and Neck Surgery (OHNS) at the University of California, San Francisco. As of 2015, he has been elected to the North American Skull Base Society Directors Board, and he is recently named the Vice Chair of the American Academy of Otolaryngology Head and Neck Surgery Skull Base Committee. He has also been the Co-Course Director for Stryker-UCSF Resident Skull Base Approaches Course since 2009. Dr. El-Sayed completed his medical degree and internship from Boston University School of Medicine in Massachusetts. He completed his otolaryngology residency from Boston University, followed by a head and neck surgical oncology fellowship from UCSF. He lectures nationally and internationally on various topics related to head and neck oncology.

Dr. El-Sayed’s clinical focus is skull base surgery and he has developed the minimally invasive program into a nationally recognized program along with his neurosurgical colleagues. The program and center offers a unique capability of providing both endoscopic and open approaches to tailor the approach to the lesion. He has a broad surgical experience having performed over 500 surgical procedures on tumors of the nasal cavity/paranasal sinuses, infratemporal fossa, skull base and pituitary glands in over a decade of experience. He is also interested in the outcomes of research and clinical innovations through novel approach development. His research program goal is to develop 1) novel endoscopic surgical approaches and 2) nanotechnologies as multifunctional theranostic devices for the detection, destruction, and monitoring of oral cancer.

Education

Brown University, Providence, Rhode Island, Sc. B, 1992, Neuroscience
Boston University Medical School, Boston, MA, M.D., 1992-1996, Medicine
Boston University Medical Ctr, Boston, MA, 1996-2001, Otolaryngology-HNS
University of California, San Francisco, Postdoctoral, 2002-2003, Head and Neck Oncology-Fellowship


Professional Experience

  • 1996-1997
    Intern, Boston University Medical Center, Worcester, MA
  • 1997-2001
    Resident in Otolaryngology, Boston Univeristy Medical Center, Worcester, MA
  • 2001-2002
    Staff Physician, Fallon Clinic Department of Otolaryngology
  • 2002-2003
    Fellow, Department of Otolaryngology, University of California, San Francisco
  • 2002-2003
    Clinical Instructor, Department of Otolaryngology, UCSF
  • 2004-2009
    Assistant Professor, Department of Otolaryngology, UCSF
  • 2009-present
    Associate Professor, Department of Otolaryngology, UCSF

Honors & Awards

  • 1995
    Member, Alpha Omega Alpha Honor Society
  • 1998
    First Place: Ethics of Cochlear Implantation in Young Children, New England Otolaryngology Society
  • 2002
    U.S. Patent: Spectroscopic Diagnostics for Bacteria in Biologic Samples. Ivan El-Sayed, MD and Mostafa El-Sayed, PhD
  • 2002-2012
    Board Certified by the American Board of Otolaryngology
  • 2003
    THANKS Star Award, UCSF Medical Center
  • 2005
    "Quality Award" UCSF Medical Center Quality Improvement Office. For: Altered Airway PI Project. Member of the committee which developed this form.
  • 2007
    U.S. Patent: GTRC 3424 U.S.S.N. 11/913,915 "Shape Tunable Plasmonic Nanoparticles" Mostafa A. El-Sayed and Ivan Homer El-Sayed (Provisional Patent Filed 2005)
  • 2007
    "Hot Paper", American Chemical Society Publications, first author. [As defined by the ACS: "Hot Papers are articles published within the last two years receiving the most citations over the most recent two-month period. In a typical two-month period, Essential Science Indicators recognizes more than 200 total Hot Papers in chemistry.] For Article: Surface Plasmon Resonance Scattering and Absorption of anti-EGFR Antibody Conjugated Gold Nanoparticles in Cancer Diagnostics: Applications in Oral Cancer. Nano Lett. 2005.
  • 2007
    Outstanding Productive Physician and Surgeon, Certificate of Accomplishment, Department of Otolaryngology, UCSF
  • 2007
    "Most Accessed Article" for the 3rd quarter of 2007, American Chemical Society Publications. For article: "Gold Nanorods for Nuclear Targeting. BioconjugChemistry 2007.
  • 2008
    "Most Accessed Article" for first quarter 2008, American Chemical Society Publications: For article: Calculated Absorption and Scattering Properties of Gold Nanoparticles of Different Size, Shape, and Composition: Applications in Biological Imaging and Biomedicine. J. Phys. Chem. B.; (Article); 2006
  • 2008
    "Editor Selected Papers in Imaging"- Bioconjugate Chemistry- For Article: Peptide-Conjugated Gold Nanorods for Nuclear Targeting. Bioconjug Chem. 2007 Sep-Oct;18(5):1490-7. Epub 2007 Jul 13.
  • 2008
    #1 ranked article in citations in the field of Chemistry for 2007. Described by ScienceWatch. For article: 14. Huang X, El-Sayed IH, Qian W, El-Sayed MA. Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods. J Am Chem Soc. 2006 Feb 15;128(6):2115-2120.
  • 2008
    "Hot Paper", American Chemical Society Publications. For article: Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods, J Am Chem Soc 2006.
  • 2008
    "Most Cited Author"- First author- recognized as one of the top 20 cited papers in Cancer Letters toward the calculation of the 2007 impact factor. Cancer Letters. 2006 Jul 28;239(1):129-35.

Selected Publications

  1. Sanmillan JL, Lawton MT, Rincon-Torroella J, El-Sayed IH, Zhang X, Meybodi AT, Gabarros A, Benet A. Assessment of the Endoscopic Endonasal Transclival Approach for Surgical Clipping of Anterior Pontine Anterior-Inferior Cerebellar Artery Aneurysms. World Neurosurg. 2016 May; 89:368-75.
    View on PubMed
  2. Chan AK, Benet A, Ohya J, Zhang X, Vogel TD, Flis DW, El-Sayed IH, Mummaneni PV. The endoscopic transoral approach to the craniovertebral junction: an anatomical study with a clinical example. Neurosurg Focus. 2016 Feb; 40(2):E11.
    View on PubMed
  3. Mabray MC, Lillaney P, Sze CH, Losey AD, Yang J, Kondapavulur S, Liu D, Saeed M, Patel A, Cooke D, Jun YW, El-Sayed I, Wilson M, Hetts SW. In Vitro Capture of Small Ferrous Particles with a Magnetic Filtration Device Designed for Intravascular Use with Intraarterial Chemotherapy: Proof-of-Concept Study. J Vasc Interv Radiol. 2016 Mar; 27(3):426-432.e1.
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  4. Jun P, Russell M, El-Sayed I, Dillon W, Glastonbury C. Invasive facial fungal infections: Orofacial soft-tissue infiltration in immunocompromised patients. Radiol Case Rep. 2013; 8(2):813.
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  5. Winkler EA, Rowland NC, Yue JK, Birk H, Ozpinar A, Tay B, Ames CP, Mummaneni PV, El-Sayed IH. A Tunneled Subcricoid Approach for Anterior Cervical Spine Reoperation: Technical and Safety Results. World Neurosurg. 2016 Feb; 86:328-35.
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  6. Markey JD, Seth R, Wang SJ, Ryan WR, El-Sayed IH, Knott PD. Anterolateral Thigh Adipofascial Flap: A New Option for Scalp Reconstruction. J Reconstr Microsurg. 2016 Feb; 32(2):160-3.
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  7. Benet A, Plata Bello J, El-Sayed I. Combined Endonasal-Transcervical Approach to a Metastatic Parapharyngeal Space Papillary Thyroid Carcinoma. Cureus. 2015 Jul; 7(7):e285.
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  8. Markey J, Benet A, El-Sayed IH. The endonasal endoscopic harvest and anatomy of the buccal fat pad flap for closure of skull base defects. Laryngoscope. 2015 Oct; 125(10):2247-52.
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  9. Jahangiri A, Chin AT, Wagner JR, Kunwar S, Ames C, Chou D, Barani I, Parsa AT, McDermott MW, Benet A, El-Sayed IH, Aghi MK. Factors predicting recurrence after resection of clival chordoma using variable surgical approaches and radiation modalities. Neurosurgery. 2015 Feb; 76(2):179-85; discussion 185-6.
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  10. Awad AJ, Mohyeldin A, El-Sayed IH, Aghi MK. Sinonasal morbidity following endoscopic endonasal skull base surgery. Clin Neurol Neurosurg. 2015 Mar; 130:162-7.
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  11. Ivan ME, Iorgulescu JB, El-Sayed I, McDermott MW, Parsa AT, Pletcher SD, Jahangiri A, Wagner J, Aghi MK. Risk factors for postoperative cerebrospinal fluid leak and meningitis after expanded endoscopic endonasal surgery. J Clin Neurosci. 2015 Jan; 22(1):48-54.
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  12. Rolston JD, Han SJ, Cotter JA, El-Sayed IH, Aghi MK. Gangliogliomas of the optic pathway. J Clin Neurosci. 2014 Dec; 21(12):2244-9.
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  13. Safaee M, Oh T, Sun MZ, Parsa AT, McDermott MW, El-Sayed IH, Bloch O. Pigmented villonodular synovitis of the temporomandibular joint with intracranial extension: A case series and systematic review. Head Neck. 2015 Aug; 37(8):1213-24.
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  14. Gruss CL, Al Komser M, Aghi MK, Pletcher SD, Goldberg AN, McDermott M, El-Sayed IH. Risk factors for cerebrospinal leak after endoscopic skull base reconstruction with nasoseptal flap. Otolaryngol Head Neck Surg. 2014 Sep; 151(3):516-21.
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  15. Yu J, Aldabagh B, Wang J, Yom SS, El-Sayed I, Knott D, McGrath MH, Arron S. Multidisciplinary management of advanced basal cell carcinoma: report of four cases. J Drugs Dermatol. 2014 May; 13(5):601-6.
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  16. Schafer AL, Mumm S, El-Sayed I, McAlister WH, Horvai AE, Tom AM, Hsiao EC, Schaefer FV, Collins MT, Anderson MS, Whyte MP, Shoback DM. Panostotic expansile bone disease with massive jaw tumor formation and a novel mutation in the signal peptide of RANK. J Bone Miner Res. 2014 Apr; 29(4):911-21.
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  17. Burke K, Benet A, Aghi MK, El-Sayed I. Impact of platybasia and anatomic variance on surgical approaches to the craniovertebral junction. Laryngoscope. 2014 Aug; 124(8):1760-6.
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  18. Ouyang D, El-Sayed IH, Yom SS. National trends in surgery for sinonasal malignancy and the effect of hospital volume on short-term outcomes. Laryngoscope. 2014 Jul; 124(7):1609-14.
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  19. Jahangiri A, Potts M, Kunwar S, Blevins L, El-Sayed IH, Aghi MK. Extended endoscopic endonasal approach for suprasellar Rathke's cleft cysts. J Clin Neurosci. 2014 May; 21(5):779-85.
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  20. Clark AJ, Jahangiri A, Garcia RM, George JR, Sughrue ME, McDermott MW, El-Sayed IH, Aghi MK. Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis. Neurosurg Rev. 2013 Jul; 36(3):349-59.
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