Bruce Faddegon, PhD

Bruce Faddegon, PhD

Professor in Residence, Department of Radiation Oncology, UCSF

Phone: (415) 353-7195 (voice)
Box 1708, UCSF
San Francisco, CA 94143-1708

View on UCSF Profiles

Cancer Center Membership

Associate Member » Breast Oncology» Prostate Cancer


University of Victoria, Victoria, Canada, B.Sc., 1977, Physics (honors)
University of British Columbia, Vancouver, Canada, M.Sc., 1983, Physics (radiobiology)
Carleton University, Ottawa, Canada, Ph.D., 1990, Physics (radiotherapy)

Professional Experience

  • 1977-80
    Geophysicist, Amoco Canada, Calgary, Alberta
  • 1982-84
    Sessional Lecturer and Laboratory Instructor, University of Victoria, Victoria, BC
  • 1984-86
    Medical Physics Resident, Ottawa Regional Cancer Center, Ottawa, Ontario
  • 1990-92
    Research Associate, Ionizing Radiation Standards, National Research Council of Canada, Ottawa, Ontario
  • 1992-93
    Medical Physicist, BC Cancer Agency, Vancouver, BC
  • 1994-98
    Medical Physicist, Toronto-Sunnybrook Regional Cancer Center, Toronto, Ontario
  • 1994-2000
    Assistant Member, School of Graduate Studies, University of Toronto, Toronto, Ontario
  • 1998-2000
    Senior Medical Physicist, Toronto-Sunnybrook Regional Cancer Center, Ontario
  • 2000-2010
    Associate Professor in Residence, Department of Radiation Oncology, University of California San Francisco
  • 2010-present
    Professor in Residence, Department of Radiation Oncology, University of California San Francisco

Honors & Awards

  • 1980
    National Science and Engineering Research Council of Canada (NSERC) scholarship for M.Sc. studies
  • 1982
    NSERC scholarship for Ph.D. studies - declined
  • 1986
    Ontario Cancer Foundation fellowship for Ph.D. studies
  • 1988
    Ontario Graduate Scholarship for Ph.D. studies
  • 1989
    American Association Physicists in Medicine (AAPM) Young Investigator's Award, Second Prize
  • 1991
    Farrington Daniels Award (AAPM)
  • 1992
    Runner-up to Sylvia Fedoruk Prize (Canadian Organization of Medical Physics)
  • 1996
    Runner-up to Sylvia Fedoruk Prize (Canadian Organization of Medical Physics)
  • 2007
    Appointed Fellow of the American Association of Physicists in Medicine

Selected Publications

  1. Shiao SL, Ruffell B, DeNardo DG, Faddegon BA, Park CC, Coussens LM. TH2-Polarized CD4+ T Cells and Macrophages Limit Efficacy of Radiotherapy. Cancer Immunol Res. 2015 May; 3(5):518-25.
    View on PubMed
  2. Testa M, Schümann J, Lu HM, Shin J, Faddegon B, Perl J, Paganetti H. Experimental validation of the TOPAS Monte Carlo system for passive scattering proton therapy. Med Phys. 2013 Dec; 40(12):121719.
    View on PubMed
  3. Ramos-Méndez J, Perl J, Faddegon B, Schümann J, Paganetti H. Geometrical splitting technique to improve the computational efficiency in Monte Carlo calculations for proton therapy. Med Phys. 2013 Apr; 40(4):041718.
    View on PubMed
  4. Perl J, Shin J, Schumann J, Faddegon B, Paganetti H. TOPAS: an innovative proton Monte Carlo platform for research and clinical applications. Med Phys. 2012 Nov; 39(11):6818-37.
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  5. Choi G, Huang B, Pinarbasi E, Braunstein SE, Horvai AE, Kogan S, Bhatia S, Faddegon B, Nakamura JL. Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms. Cancer Res. 2012 Dec 15; 72(24):6425-34.
    View on PubMed
  6. Schümann J, Paganetti H, Shin J, Faddegon B, Perl J. Efficient voxel navigation for proton therapy dose calculation in TOPAS and Geant4. Phys Med Biol. 2012 Jun 7; 57(11):3281-93.
    View on PubMed
  7. Shin J, Perl J, Schümann J, Paganetti H, Faddegon BA. A modular method to handle multiple time-dependent quantities in Monte Carlo simulations. Phys Med Biol. 2012 Jun 7; 57(11):3295-308.
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  8. Schreiber EC, Sawkey DL, Faddegon BA. Sensitivity analysis of an asymmetric Monte Carlo beam model of a Siemens Primus accelerator. J Appl Clin Med Phys. 2012; 13(2):3402.
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  9. O'Shea TP, Ge Y, Foley MJ, Faddegon BA. Characterization of an extendable multi-leaf collimator for clinical electron beams. Phys Med Biol. 2011 Dec 7; 56(23):7621-38.
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  10. Ge Y, Faddegon BA. Study of intensity-modulated photon-electron radiation therapy using digital phantoms. Phys Med Biol. 2011 Oct 21; 56(20):6693-708.
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  11. O'Shea TP, Foley MJ, Faddegon BA. Accounting for the fringe magnetic field from the bending magnet in a Monte Carlo accelerator treatment head simulation. Med Phys. 2011 Jun; 38(6):3260-9.
    View on PubMed
  12. Nakamura JL, Phong C, Pinarbasi E, Kogan SC, Vandenberg S, Horvai AE, Faddegon BA, Fiedler D, Shokat K, Houseman BT, Chao R, Pieper RO, Shannon K. Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice. Cancer Res. 2011 Jan 1; 71(1):106-15.
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  13. Halabi T, Faddegon B. Practical quantitative measurement of graticule misalignment relative to collimator axis of rotation. J Appl Clin Med Phys. 2010; 11(4):3318.
    View on PubMed
  14. O'Shea TP, Sawkey DL, Foley MJ, Faddegon BA. Monte Carlo commissioning of clinical electron beams using large field measurements. Phys Med Biol. 2010 Jul 21; 55(14):4083-105.
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  15. Faddegon BA, Aubin M, Bani-Hashemi A, Gangadharan B, Gottschalk AR, Morin O, Sawkey D, Wu V, Yom SS. Comparison of patient megavoltage cone beam CT images acquired with an unflattened beam from a carbon target and a flattened treatment beam. Med Phys. 2010 Apr; 37(4):1737-41.
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  16. Sawkey D, Lu M, Morin O, Aubin M, Yom SS, Gottschalk AR, Bani-Hashemi A, Faddegon BA. A diamond target for megavoltage cone-beam CT. Med Phys. 2010 Mar; 37(3):1246-53.
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  17. Sawkey D, Faddegon BA. Simulation of large x-ray fields using independently measured source and geometry details. Med Phys. 2009 Dec; 36(12):5622-32.
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  18. Fragoso M, Kawrakow I, Faddegon BA, Solberg TD, Chetty IJ. Fast, accurate photon beam accelerator modeling using BEAMnrc: a systematic investigation of efficiency enhancing methods and cross-section data. Med Phys. 2009 Dec; 36(12):5451-66.
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  19. Faddegon BA, Sawkey D, O'Shea T, McEwen M, Ross C. Treatment head disassembly to improve the accuracy of large electron field simulation. Med Phys. 2009 Oct; 36(10):4577-91.
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  20. Faddegon BA, Kawrakow I, Kubyshin Y, Perl J, Sempau J, Urban L. The accuracy of EGSnrc, Geant4 and PENELOPE Monte Carlo systems for the simulation of electron scatter in external beam radiotherapy. Phys Med Biol. 2009 Oct 21; 54(20):6151-63.
    View on PubMed

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