Danica Galonić Fujimori, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
fujimori_danica

Assistant Professor of Cellular and Molecular Pharmacology and Pharmaceutical Chemistry, UCSF

danica.fujimori@ucsf.edu

Phone: (415) 514-0147
Box 2280, UCSF
San Francisco, CA 94143-2280

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Additional Websites


Education

University of Belgrade, Belgrade, Serbia BSc 07/2000 Chemistry
University of Illinois, Urbana, IL PhD 05/2005 Chemistry
Harvard Medical School, Boston, MA Postdoc 06/2008 Biochemistry
 

 


Professional Experience

  • 7/05-6/08
    Postdoctoral Fellow, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
  • 7/08-pres.
    Assistant Professor, Department of Cellular and Molecular Pharmacology, Department of Pharmaceutical Chemistry, University of California San Francisco

Honors & Awards

  • 2000
    Serbian Chemical Society Outstanding Undergraduate Student Award
  • 2001
    University of Illinois Teachers Rated as Excellent
  • 2003
    Procter and Gamble Predoctoral Fellowship
  • 2004
    University of Illinois Pines Predoctoral Fellowship
  • 2005
    Damon Runyon Cancer Research Foundation Postdoctoral Fellowship
  • 2007
    NIH Pathway to Independence Award
  • 2009
    Kimmel Scholar Award
  • 2010
    V Foundation Scholar Award
  • 2011
    Basil O'Connor Starter Scholar Award, March of Dimes
  • 2011
    NSF CAREER Award
  • 2011
    Searle Scholar Award

Selected Publications

  1. Fujimori DG. Radical SAM-mediated methylation reactions. Curr Opin Chem Biol. 2013 Aug; 17(4):597-604.
    View on PubMed
  2. Shiau C, Trnka MJ, Bozicevic A, Ortiz Torres I, Al-Sady B, Burlingame AL, Narlikar GJ, Fujimori DG. Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase. Chem Biol. 2013 Apr 18; 20(4):494-9.
    View on PubMed
  3. Le DD, Cortesi AT, Myers SA, Burlingame AL, Fujimori DG. Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding. J Am Chem Soc. 2013 Feb 27; 135(8):2879-82.
    View on PubMed
  4. McCusker KP, Medzihradszky KF, Shiver AL, Nichols RJ, Yan F, Maltby DA, Gross CA, Fujimori DG. . Covalent Intermediate in the Catalytic Mechanism of the Radical S-Adenosyl-l-methionine Methyl Synthase RlmN Trapped by Mutagenesis. J Am Chem Soc. 2012; 134(43):18074-81.
    View on PubMed
  5. Le DD, Fujimori DG. Protein and nucleic acid methylating enzymes: mechanisms and regulation. Curr Opin Chem Biol. 2012 Dec; 16(5-6):507-15.
    View on PubMed
  6. McCusker KP, Fujimori DG. The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. ACS Chem Biol. 2012 Jan 20; 7(1):64-72.
    View on PubMed
  7. Yan F, Fujimori DG. RNA methylation by radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift. Proc Natl Acad Sci U S A. 2011 Mar 8; 108(10):3930-4.
    View on PubMed
  8. Yan F, LaMarre JM, Röhrich R, Wiesner J, Jomaa H, Mankin AS, Fujimori DG. RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA. J Am Chem Soc. 2010 Mar 24; 132(11):3953-64.
    View on PubMed
  9. Wong C, Fujimori DG, Walsh CT, Drennan CL. Structural analysis of an open active site conformation of nonheme iron halogenase CytC3. J Am Chem Soc. 2009 Apr 8; 131(13):4872-9.
    View on PubMed
  10. Fujimori DG. Hypoxia sensing goes gauche. Nat Chem Biol. 2009 Apr; 5(4):202-3.
    View on PubMed
  11. Neumann CS, Fujimori DG, Walsh CT. Halogenation strategies in natural product biosynthesis. Chem Biol. 2008 Feb; 15(2):99-109.
    View on PubMed
  12. Neidig ML, Brown CD, Light KM, Fujimori DG, Nolan EM, Price JC, Barr EW, Bollinger JM, Krebs C, Walsh CT, Solomon EI. CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases. J Am Chem Soc. 2007 Nov 21; 129(46):14224-31.
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  13. Fujimori DG, Barr EW, Matthews ML, Koch GM, Yonce JR, Walsh CT, Bollinger JM, Krebs C, Riggs-Gelasco PJ. Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces. J Am Chem Soc. 2007 Nov 7; 129(44):13408-9.
    View on PubMed
  14. Fujimori DG, Hrvatin S, Neumann CS, Strieker M, Marahiel MA, Walsh CT. Cloning and characterization of the biosynthetic gene cluster for kutznerides. Proc Natl Acad Sci U S A. 2007 Oct 16; 104(42):16498-503.
    View on PubMed
  15. Fujimori DG, Walsh CT. What's new in enzymatic halogenations. Curr Opin Chem Biol. 2007 Oct; 11(5):553-60.
    View on PubMed
  16. Krebs C, Galonic Fujimori D, Walsh CT, Bollinger JM. Non-heme Fe(IV)-oxo intermediates. Acc Chem Res. 2007 Jul; 40(7):484-92.
    View on PubMed
  17. Galonic DP, Gin DY. Chemical glycosylation in the synthesis of glycoconjugate antitumour vaccines. Nature. 2007 Apr 26; 446(7139):1000-7.
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  18. Kelly WL, Boyne MT, Yeh E, Vosburg DA, Galonic DP, Kelleher NL, Walsh CT. Characterization of the aminocarboxycyclopropane-forming enzyme CmaC. Biochemistry. 2007 Jan 16; 46(2):359-68.
    View on PubMed
  19. Galonic DP, Barr EW, Walsh CT, Bollinger JM, Krebs C. Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3. Nat Chem Biol. 2007 Feb; 3(2):113-6.
    View on PubMed
  20. Ueki M, Galonic DP, Vaillancourt FH, Garneau-Tsodikova S, Yeh E, Vosburg DA, Schroeder FC, Osada H, Walsh CT. Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete. Chem Biol. 2006 Nov; 13(11):1183-91.
    View on PubMed

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