Associate Professor, Departments of Neurological Surgery and Pediatrics, UCSF
Dennis Bruce Dettmer Endowed Chair in Pediatric Neurosurgery, UCSF
Additional Websites
Education
Faculty of Science, McGill University, Montreal, Canada, 1981-1983, Program in Biology
Faculty of Medicine, University of Toronto, Canada, MD, 1987, Medicine
Mt. Sinai Hospital, Faculty of Medicine, University of Toronto, Canada, Internship, 1987-1988, Surgery
Dept. of Surgery, University of Ottawa and University of Toronto, Canada, Residency, 1988-1996, Neurosurgery
University of California, San Francisco, PhD, 1996, Biochemistry / Biophysics
Hospital for Sick Children, Toronto, Canada, 1997-98, Peds Neurosurgery
Professional Experience
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1998 - 2000
Clinical Associate, Section of Neurosurgery, Department of Surgery, University of Chicago
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2000 - 2007
Assistant Professor, Departments of Neurosurgery and Pediatrics, University of California San Francisco
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2000 - present
Principal Investigator, Brain Tumor Research Center, Department of Neurosurgery, UCSF
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2001 - present
Bruce Dettmer Endowed Chair in Pediatric Neurosurgery, UCSF
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2001-present
Chief, Division of Pediatric Neurosurgery, UCSF
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2007 - present
Associate Professor, Departments of Neurosurgery and Pediatrics, UCSF
Honors & Awards
- 1981
J.W. McConnell Scholarship, McGill University - 1988
Outstanding Intern, Department of Emergency Medicine, Mount Sinai Hospital - 1989
Resident Teaching Award, St. Michael's Hospital, Toronto - 1994
Student Travel Award, Radiation Research Society - 1995
Junior Scientist Travel Award, International Congress of Radiation Research - 1995
T.P. Morley Resident Research Award, Division of Neurosurgery, University of Toronto - 1997
Resident Teaching Award, St. Michael's Hospital, Toronto - 1997
Alan Hudson Resident Teaching Award, Division of Neurosurgery, University of Toronto - 2003
Hellman Family Research Award for Junior Faculty, UCSF - 2004
Career Development Award, SPORE Grant, UCSF
Selected Publications
- Silber J, Hashizume R, Felix T, Hariono S, Yu M, Berger MS, Huse JT, Vandenberg SR, James CD, Hodgson JG, Gupta N. Expression of miR-124 inhibits growth of medulloblastoma cells. Neuro Oncol. 2013 Jan; 15(1):83-90.
View on PubMed - Hashizume R, Smirnov I, Liu S, Phillips JJ, Hyer J, McKnight TR, Wendland M, Prados M, Banerjee A, Nicolaides T, Mueller S, James CD, Gupta N. Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment. J Neurooncol. 2012 Dec; 110(3):305-13.
View on PubMed - Clark AJ, Cage TA, Aranda D, Parsa AT, Auguste KI, Gupta N. Treatment-related morbidity and the management of pediatric craniopharyngioma: a systematic review. J Neurosurg Pediatr. 2012 Oct; 10(4):293-301.
View on PubMed - Engler JR, Robinson AE, Smirnov I, Hodgson JG, Berger MS, Gupta N, James CD, Molinaro A, Phillips JJ. Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PLoS One. 2012; 7(8):e43339.
View on PubMed - Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, Dubuc A, Yao Y, Ramaswamy V, Luu B, Rolider A, Cavalli FM, Wang X, Remke M, Wu X, Chiu RY, Chu A, Chuah E, Corbett RD, Hoad GR, Jackman SD, Li Y, Lo A, Mungall KL, Nip KM, Qian JQ, Raymond AG, Thiessen NT, Varhol RJ, Birol I, Moore RA, Mungall AJ, Holt R, Kawauchi D, Roussel MF, Kool M, Jones DT, Witt H, Fernandez-L A, Kenney AM, Wechsler-Reya RJ, Dirks P, Aviv T, Grajkowska WA, Perek-Polnik M, Haberler CC, Delattre O, Reynaud SS, Doz FF, Pernet-Fattet SS, Cho BK, Kim SK, Wang KC, Scheurlen W, Eberhart CG, Fèvre-Montange M, Jouvet A, Pollack IF, Fan X, Muraszko KM, Gillespie GY, Di Rocco C, Massimi L, Michiels EM, Kloosterhof NK, French PJ, Kros JM, Olson JM, Ellenbogen RG, Zitterbart K, Kren L, Thompson RC, Cooper MK, Lach B, McLendon RE, Bigner DD, Fontebasso A, Albrecht S, Jabado N, Lindsey JC, Bailey S, Gupta N, Weiss WA, Bognár L, Klekner A, Van Meter TE, Kumabe T, Tominaga T, Elbabaa SK, Leonard JR, Rubin JB, Liau LM, Van Meir EG, Fouladi M, Nakamura H, Cinalli G, Garami M, Hauser P, Saad AG, Iolascon A, Jung S, Carlotti CG, Vibhakar R, Ra YS, Robinson S, Zollo M, Faria CC, Chan JA, Levy ML, Sorensen PH, Meyerson M, Pomeroy SL, Cho YJ, Bader GD, Tabori U, Hawkins CE, Bouffet E, Scherer SW, Rutka JT, Malkin D, Clifford SC, Jones SJ, Korbel JO, Pfister SM, Marra MA, Taylor MD. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 2012 Aug 2; 488(7409):49-56.
View on PubMed - Cage TA, Mueller S, Haas-Kogan D, Gupta N. High-grade gliomas in children. Neurosurg Clin N Am. 2012 Jul; 23(3):515-23.
View on PubMed - Gupta N, Farrell JA, Rand L, Cauldwell CB, Farmer D. Open fetal surgery for myelomeningocele. J Neurosurg Pediatr. 2012 Mar; 9(3):265-73.
View on PubMed - Witt H, Mack SC, Ryzhova M, Bender S, Sill M, Isserlin R, Benner A, Hielscher T, Milde T, Remke M, Jones DT, Northcott PA, Garzia L, Bertrand KC, Wittmann A, Yao Y, Roberts SS, Massimi L, Van Meter T, Weiss WA, Gupta N, Grajkowska W, Lach B, Cho YJ, von Deimling A, Kulozik AE, Witt O, Bader GD, Hawkins CE, Tabori U, Guha A, Rutka JT, Lichter P, Korshunov A, Taylor MD, Pfister SM. Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell. 2011 Aug 16; 20(2):143-57.
View on PubMed - Cage TA, Auguste KI, Wrensch M, Wu YW, Gupta N. Self-reported functional outcome after surgical intervention in patients with idiopathic normal pressure hydrocephalus. J Clin Neurosci. 2011 May; 18(5):649-54.
View on PubMed - Adzick NS, Thom EA, Spong CY, Brock JW, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, D'Alton ME, Farmer DL. A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med. 2011 Mar 17; 364(11):993-1004.
View on PubMed - Gupta N, Kaur J, Rajwanshi A, Nijhawan R, Srinivasan R, Dey P, Singh U, Gupta P. Spectrum of orbital and ocular adnexal lesions: an analysis of 389 cases diagnosed by fine needle aspiration cytology. Diagn Cytopathol. 2012 Jul; 40(7):582-5.
View on PubMed - Vanniarajan A, Govindaraj P, Carlus SJ, Aruna M, Aruna P, Kumar A, Jayakar RI, Lionel AC, Gupta S, Rao L, Gupta NJ, Chakravarthy B, Deenadayal M, Selvaraj K, Andal S, Reddy BM, Singh L, Thangaraj K. Mitochondrial DNA variations associated with recurrent pregnancy loss among Indian women. Mitochondrion. 2011 May; 11(3):450-6.
View on PubMed - Hashizume R, Gupta N, Berger MS, Banerjee A, Prados MD, Ayers-Ringler J, James CD, VandenBerg SR. Morphologic and molecular characterization of ATRT xenografts adapted for orthotopic therapeutic testing. Neuro Oncol. 2010 Apr; 12(4):366-76.
View on PubMed - Sanai N, Wachhorst SP, Gupta NM, McDermott MW. Transcerebellar stereotactic biopsy for lesions of the brainstem and peduncles under local anesthesia. Neurosurgery. 2008 Sep; 63(3):460-6; discussion 466-8.
View on PubMed - Wu Y, Green NL, Wrensch MR, Zhao S, Gupta N. Ventriculoperitoneal shunt complications in California: 1990 to 2000. Neurosurgery. 2007 Sep; 61(3):557-62; discussion 562-3.
View on PubMed - Dinca EB, Sarkaria JN, Schroeder MA, Carlson BL, Voicu R, Gupta N, Berger MS, James CD. Bioluminescence monitoring of intracranial glioblastoma xenograft: response to primary and salvage temozolomide therapy. J Neurosurg. 2007 Sep; 107(3):610-6.
View on PubMed - Liang Y, Bollen AW, Gupta N. CC chemokine receptor-2A is frequently overexpressed in glioblastoma. J Neurooncol. 2008 Jan; 86(2):153-63.
View on PubMed - Liang Y, Diehn M, Bollen AW, Israel MA, Gupta N. Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment. J Neurooncol. 2008 Jan; 86(2):133-41.
View on PubMed - Gupta N, Park J, Solomon C, Kranz DA, Wrensch M, Wu YW. Long-term outcomes in patients with treated childhood hydrocephalus. J Neurosurg. 2007 May; 106(5 Suppl):334-9.
View on PubMed - Hsieh MH, Perry V, Gupta N, Pearson C, Nguyen HT. The effects of detethering on the urodynamics profile in children with a tethered cord. J Neurosurg. 2006 Nov; 105(5 Suppl):391-5.
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