Research Summary

I am a Professor in Residence in the HIV, ID, and Global Medicine Division in the Department of Medicine.

Substance use plays important biological and behavioral roles in health outcomes, and my work consists of epidemiology at the intersection of substance use and infectious diseases. My research team is currently conducting several NIH-funded studies to examine the use of TB prophylaxis in HIV/TB co-infected alcohol users, as well as interventions to reduce drinking and increase antiretroviral therapy adherence. We are using novel biomarkers of alcohol consumption and INH pill-taking to gain objective measurements where self-report is problematic. I am also teaching and mentoring via a K-24 award, and grant-writing courses in Epidemiology and Biostatistics and the UCSF CTSI KL2 Scholars Program.

Research Funding

  • September 25, 2025 - August 31, 2030 - Center for Alcohol/HIV Innovations and Biomarker Research (CALIBER) , Principal Investigator . Sponsor: NIH, Sponsor Award ID: P60AA032189
  • June 1, 2024 - May 31, 2027 - The Phosphatidylethanol (PEth) Results Communication (PERC) Study , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R34AA031652
  • September 10, 2021 - August 31, 2026 - The International Uganda Russia Boston Alcohol Network for Alcohol Research Collaboration on HIV/AIDS (URBAN ARCH) Center , Co-Investigator; Uganda project PI . Sponsor: NIH, Sponsor Award ID: P01AA029541
  • May 1, 2022 - February 28, 2025 - Biomarkers for Alcohol/HIV Research (BAHR) Study , Principal Investigator . Sponsor: NIH, Sponsor Award ID: NIH R01AA029962
  • September 15, 2013 - April 30, 2024 - Training in Research Program on Alcohol Use by Persons with our at Risk for HIV , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K24AA022586
  • September 15, 2017 - August 31, 2022 - Interventions to reduce alcohol use and increase adherence to TB preventive therapy among HIV/TB co-infected drinkers (DIPT 1/2) , Principal Investigator . Sponsor: NIH, Sponsor Award ID: U01AA026223
  • September 20, 2011 - August 31, 2022 - URBAN ARCH (3/5) Uganda Cohort TB preventive therapy for HIV-infected alcohol users in Uganda: an evaluation of safety tolerability and adherence , Principal Investigator . Sponsor: NIH, Sponsor Award ID: U01AA020776
  • April 1, 2017 - March 31, 2021 - Mobile technology to extend clinic-based counseling for HIV+s in Uganda , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AA024990
  • July 15, 2010 - March 31, 2015 - Changes in Alcohol Consumption in HIV Positives in Uganda , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R01AA018631
  • June 20, 2007 - May 31, 2012 - Dynamic Modeling of the HCV Epidemic in IDU , Principal Investigator . Sponsor: NIH, Sponsor Award ID: K01DA023365
  • September 30, 2006 - August 31, 2009 - Measurement of Alcohol Use Among HIV-Positives in Uganda , Principal Investigator . Sponsor: NIH, Sponsor Award ID: R21AA015897

Education

Cornell University, Ithaca, NY, B.S., 5/1987, Statistics and Biometry
University of California, Berkeley, CA, M.A., 5/1989, Biostatistics
University of California, Berkeley, CA, Doctoral Student, 1989-1990, Biostatistics
University of California, Berkeley, CA, Ph.D., 5/2001, Epidemiology

Honors & Awards

  • 2009-2010
    Hellman Family Award for Early Career Faculty, UCSF
  • 2013-present
    NIH Center for Scientific Review: Behavioral and Social Science Approaches to Preventing HIV/AIDS (BSPH) Study Section ad hoc reviewer and Special Emphasis Panel reviewer (4 times) and Chair (2 times), Population and Public Health Approaches to HIV/ADS (PPAH) ad hoc reviewer (1 time)
  • 2015
    mHealth Summer Training Institute (UCLA) selected participant

Selected Publications

  1. Hahn JA, Kane JC, Fatch R, Espinosa da Silva C, Emenyonu NI, Scheffler A, Chirayil P, So-Armah K, Kahler CW, Conroy AA, Edelman EJ, Woolf-King S, Parry CD, Kiene SM, Chamie G, Muyindike WR, Adong J, Go VF, Cook RL, Morojele NK, Fiellin DA, Santos GM, Tahir P, Samet J, Krupitsky E, Allen IE Alcohol interventions for persons with HIV: Meta-analysis of randomized controlled trials using phosphatidylethanol and self-report.  View on PubMed
  2. Kiene SM, Miller AP, Ediau M, Tuhebwe D, Sileo KM, Naigino R, Hahn JA, Reed E, Anecho A, Mukasa B, Lin CD, Wanyenze RK, Tumwesigye NM A pilot randomized controlled trial of Kisoboka, a behavioral economic and motivational interviewing intervention to reduce high-risk alcohol use and improve antiretroviral therapy adherence for men in Uganda.  View on PubMed
  3. Kane JC, Chirayil P, Pawar R, Inoue S, Hofer T, McDonell M, Latkin C, Chander G, Martins SS, Greene MC, Vinikoor M, Sharma A, Hahn JA Measuring alcohol consumption with biomarkers in intervention studies: A scoping review.  View on PubMed
  4. Paniagua-Avila A, Kanguya T, Mwamba C, Hahn JA, Latkin C, Chander G, Martins SS, Munthali S, McDonell MG, Sharma A, Kane J Contextual factors and implementation strategies for a biomarker-augmented alcohol screening with brief intervention and referral to treatment (SBIRT) program for HIV-affected adolescents in Zambia: a qualitative study guided by RE-AIM / PRISM.  View on PubMed
  5. Conroy AA, Butterfield RM, Chibi B, Hahn JA, Neilands TB, Msimango L, van Heerden A, Humphries H, Starks TJ Pilot Results of Masibambisane: Couples Motivational Interviewing with Mobile Breathalyzers to Address Unhealthy Drinking and Adherence to Antiretroviral Therapy in South Africa.  View on PubMed
  6. Odokonyero RF, Muhwezi WW, Musanje K, Sanyu N, Muyindike WR, Katahoire AR, Camlin CS, Hahn JA, Nakasujja N The Lived Experiences of Unhealthy Alcohol Use among Young People with HIV in Southwestern Uganda.  View on PubMed
  7. Lancaster KE, Bula AK, Matoga MM, Hosseinipour MC, Hoffman IF, Grullon JA, Umar E, Msolola J, Magidson JF, Bonumwezi JL, Hahn JA, Parcesepe AM Testing a systematically braided alcohol reduction and HIV status neutral intervention among people receiving STI care in Malawi: study protocol for a pilot hybrid type 1 effectiveness-implementation randomized controlled trial.  View on PubMed
  8. Castle AC, Busang J, Dreyer J, Herbst C, Okesola N, Chimbindi N, Zuma T, Jarolimova J, Hahn JA, Psaros C, Shenoi SV, Shahmanesh M, Siedner MJ Alcohol Use and the Pre-exposure Prophylaxis Continuum of Care Among Men in Rural South Africa: Results from a Longitudinal Study.  View on PubMed
  9. Abbott R, Landsiedel K, Atukunda M, Puryear SB, Chamie G, Hahn JA, Mwangwa F, Kakande E, Petersen ML, Havlir DV, Charlebois E, Balzer LB, Kamya MR, Marquez C. Incident Tuberculosis Infection Is Associated With Alcohol Use in Adults in Rural Uganda. Clin Infect Dis. 2025 Mar 17; 80(3):562-565.  View on PubMed
  10. Mkandawire J, Ssewamala FM, Hahn JA, Mulauzi N, Neilands TB, Tebbetts S, Darbes LA, Brown DS, Conroy AA. Economic and relationship-strengthening intervention to reduce alcohol use in couples living with HIV in Malawi: a study protocol for a randomised controlled trial of Mlambe. BMJ Open. 2025 Feb 10; 15(2):e097247.  View on PubMed
  11. Muyindike WR, Fatch R, Lodi S, Emenyonu NI, Kekibiina A, Adong J, Beesiga B, Marson K, Thirumurthy H, McDonell MG, Kamya MR, Chamie G, Hahn JA. Alcohol use and HIV suppression after completion of financial incentives for alcohol abstinence and isoniazid adherence: a randomized controlled trial. EClinicalMedicine. 2025 Feb; 80:103045.  View on PubMed
  12. Hahn JA, Piano MR, Hwang CL, Justice AC. Phosphatidylethanol Can Improve Detection and Treatment of Unhealthy Alcohol Use. Am J Prev Med. 2025 Mar; 68(3):638-641.  View on PubMed
  13. Murnane PM, Afshar M, Chamie G, Cook RL, Ferguson T, Haque LY, Jacobson KR, Justice AC, Kim TW, Khalili M, Krupitsky E, McGinnis KA, Molina P, Muyindike WR, Myers B, Richards VL, So-Armah K, Stewart S, Sulkowski MS, Tien PC, Hahn JA. Using Phosphatidylethanol as an Adjunct to Self-Reported Alcohol Use Improves Identification of Liver Fibrosis Risk. Am J Gastroenterol. 2024 Oct 31.  View on PubMed
  14. Conroy AA, Ruark A, Mulauzi N, Mkandawire J, Darbes LA, Hahn JA, Neilands TB, Tebbetts S, Ssewamala FM. Mlambe economic and relationship-strengthening intervention for alcohol use decreases violence and improves relationship quality in couples living with HIV in Malawi. Soc Sci Med. 2024 Dec; 362:117407.  View on PubMed
  15. Jain JP, Ma Y, Dawson-Rose C, Santos GM, Han A, Price J, Hahn JA, Tien PC. The prevalence and correlates of biomarker positive unhealthy alcohol use among women living with and without HIV in San Francisco, California. PLoS One. 2024; 19(10):e0308867.  View on PubMed
  16. Odokonyero RF, Nakasujja N, Turiho A, Sanyu N, Muyindike WR, Nansera D, Semitala F, Kamya MR, Katahoire AR, Hahn JA, Camlin CC, Muhwezi WW. Provider perceptions of young people living with HIV and unhealthy alcohol use in Southwestern Uganda: a qualitative study. Addict Sci Clin Pract. 2024 Sep 02; 19(1):62.  View on PubMed
  17. Savinkina A, Muyindike W, Hahn JA, Emenyonu NI, Fatch R, Ngabirano C, Adong J, Jacobson KR, Linas BP. Strategies for isoniazid preventive therapy in HIV-positive patients who consume alcohol. Int J Tuberc Lung Dis. 2024 Jul 01; 28(7):335-342.  View on PubMed
  18. Espinosa da Silva C, Fatch R, Emenyonu N, Muyindike W, Adong J, Rao SR, Chamie G, Ngabirano C, Tumwegamire A, Kekibiina A, Marson K, Beesiga B, Sanyu N, Katusiime A, Hahn JA. Psychometric assessment of the Runyankole-translated Marlowe-Crowne Social Desirability Scale among persons with HIV in Uganda. BMC Public Health. 2024 06 19; 24(1):1628.  View on PubMed
  19. Asiimwe SB, Kekibiina A, Woolf-King SE, Fatch R, Emenyonu N, Hahn JA. Alcohol Consumption Among Persons Living with HIV: Perceptions, Messages and Interventions-A Qualitative Study at an HIV Treatment Clinic in South Western Uganda. AIDS Behav. 2024 Aug; 28(8):2559-2576.  View on PubMed
  20. Appa A, Miller AP, Fatch R, Kekibiina A, Beesiga B, Adong J, Emenyonu N, Marson K, Getahun M, Kamya M, Muyindike W, McDonell M, Thirumurthy H, Hahn JA, Chamie G, Camlin CS. Participant perspectives on incentives for TB preventative therapy adherence and reduced alcohol use: A qualitative study. PLOS Glob Public Health. 2024; 4(4):e0002472.  View on PubMed

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