University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Steven Hetts, MD

Steven Hetts, MD

Associate Professor in Residence of Radiology and Biomedical Imaging, UCSF

Cancer Center Program Memberships

Pediatric Malignancies

Research Summary

Steven Hetts, MD, is an Associate Professor of Radiology in Residence at the University of California, San Francisco, and he is Chief of Neuroradiology at the San Francisco General Hospital where he has established a new clinical Interventional Neuroradiology service, providing cutting edge minimally invasive endovascular therapy. Dr. Hetts received his medical degree from Harvard Medical School in Boston, Massachusetts in 2000, and completed a residency in Diagnostic Radiology at UCSF, followed by a fellowship in Diagnostic Neuroradiology and Interventional Neuroradiology from UCSF.

Dr. Hetts is involved in translational research as Co-Director of the Interventional Radiology Laboratory at China Basin, including the conception, performance, and management of research projects translating basic science and engineering research into clinical applicability. One of his projects is Magnetic Catheter Navigation and Microinfarction Evaluation in the Brain and Heart. Dr. Hetts also implements many clinical research projects involving retrospective and prospective patient data. The main focus of his clinical research is endovascular therapy for cerebrovascular disease, spinal vascular disease, and neurooncology.

Education

Harvard College, Boston, MA, AB summa cum laude, 06/1996, Biology
Harvard Medical School, Boston, MA, MD, 06/2000, Medicine
Stanford University Medical Center, Stanford, CA, Internship, 06/2001, Internal Medicine
UCSF Medical Center, San Francisco, CA, Residency, 06/2005, Diagnostic Radiology
UCSF Medical Center, San Francisco, CA, Fellowship, 06/2006, Diagnostic Neuroradiology
UCSF Medical Center, San Francisco, CA, Fellowship, 02/2008, Interventional Neuroradiology


Professional Experience

  • 1991-1992
    Research Associate, Department of Cell Genetics, Genentech, Inc., South San Francisco, CA
  • 1993
    Research Associate, UCSF Department of Radiology
  • 1993
    Research Associate, UCSF Center for Medical Technology Assessment
  • 1994
    Research Associate, The Parkinson’s Institute, Sunnyvale, CA
  • 1994-1996
    Research Associate, Department of Neurology, Children’s Hospital, Boston, MA
  • 1997
    Research Associate, Department of Biology, Tularik, Inc., South San Francisco, CA
  • 2000-2001
    Intern Physician in Internal Medicine, Stanford University Hospital
  • 2001-2005
    Resident Physician in Diagnostic Radiology, UCSF Medical Center
  • 2003-2007
    Co-Investigator, NIH R01 HL076486 (Wilson), UCSF Medical Center 
  • 2005-2006
    Clinical Fellow in Diagnostic Neuroradiology, UCSF Medical Center
  • 2006-2008
    Clinical Fellow in Interventional Neuroradiology, UCSF Medical Center
  • 2008-2013
    Assistant Professor in Residence, Radiology, UCSF
  • 2008-2015
    Chief of Interventional Neuroradiology, San Francisco General Hospital
  • 2008-2015
    Chief of Interventional Neuroradiology, San Francisco VA Medical Center
  • 2008-current
    Attending Interventional Neuroradiologist, UCSF Medical Center
  • 2009-current
    Co-Director, UCSF/SFGH Interventional Radiology Research Laboratory
  • 2009-2010
    Co-Director, Neurovascular/Neurointerventional Research Interest Group, UCSF Radiology
  • 2010-current
    Co-Director, Image-Guided Therapy Specialized Resource Group, UCSF Radiology
  • 2013-current
    Chief Medical Officer and Co-Founder, ChemoFilter, Inc., Hillsborough, CA
  • 2013-current
    Associate Professor in Residence, Radiology, UCSF 
  • 2014-current
    Co-Director, UCSF Hereditary Hemorrhagic Telangiectasia Center of Excellence
  • 2015-current
    Chief of Interventional Neuroradiology, UCSF Benioff Children’s Hospital, UCSF Betty Irene Moore Women’s Hospital, and UCSF Bakar Cancer Hospital

Honors & Awards

  • 1992
    United States Presidential Scholar, highest academic honor for US high school students
  • 1993-1996
    John Harvard Scholarship and Dean’s List, Harvard College
  • 1995
    Phi Beta Kappa, elected in Senior 45, Harvard College
  • 1996
    Biology Undergraduate Honors Thesis, summa cum laude
  • 1997
    Finalist, Rhodes Scholarship, California Nominee to Region VIII Competition
  • 1999
    Aesculapian Club, Harvard Medical School
  • 2001
    Nominee, Resident Teaching Award, Department of Internal Medicine, Stanford Hospital
  • 2002, 2003
    Margulis Society Radiology Resident Research Award
  • 2003
    American Roentgen Ray Society Introduction to Research Program
  • 2004
    International Society for Magnetic Resonance in Medicine Amersham Fellowship
  • 2004
    American Society of Pediatric Neuroradiology Annual Research Award
  • 2005
    Executive Council Award, Residents in Radiology Competition, American Roentgen Ray Society
  • 2010, 2011
    American Society of Neuroradiology, Neuroradiology Research and Education Foundation Scholar Award in Neuroradiology Research
  • 2012
    Visiting Professor, Memorial Sloan Kettering Cancer Center
  • 2015
    Nominee, QB3 Award for Startup of the Year, ChemoFilter
  • 2015
    Fellow, Rosenman Institute, UCSF

Selected Publications

  1. Maani N, Hetts SW, Rayz VL. A two-scale approach for CFD modeling of endovascular Chemofilter device. Biomech Model Mechanobiol. 2018 Jul 31.
    View on PubMed
  2. Blumenfeld CM, Schulz MD, Aboian MS, Wilson MW, Moore T, Hetts SW, Grubbs RH. Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles. Nat Commun. 2018 Jul 20; 9(1):2870.
    View on PubMed
  3. Lee SK, Mokin M, Hetts SW, Fifi JT, Bousser MG, Fraser JF. Current endovascular strategies for cerebral venous thrombosis: report of the SNIS Standards and Guidelines Committee. J Neurointerv Surg. 2018 Jun 05.
    View on PubMed
  4. Jordan CD, Han M, Kondapavulur S, Vera DB, Neumann KD, Moore T, Stillson C, Krug R, Behr S, Seo Y, VanBrocklin HF, Larson PEZ, Wilson M, Martin AJ, Hetts SW. Quantification of 89 Zr-Iron oxide nanoparticle biodistribution using PET-MR and ultrashort TE sequences. J Magn Reson Imaging. 2018 May 14.
    View on PubMed
  5. Talbott JF, Cooke DL, Mabray MC, Larson PS, Amans MR, Hetts SW, Wilson MW, Moore T, Salegio EA. Accuracy of image-guided percutaneous injection into a phantom spinal cord utilizing flat panel detector CT with MR fusion and integrated navigational software. J Neurointerv Surg. 2018 Apr 17.
    View on PubMed
  6. LaHue SC, Kim H, Pawlikowska L, Nelson J, Cooke DL, Hetts SW, Singh V. Frequency and characteristics associated with inherited thrombophilia in patients with intracranial dural arteriovenous fistula. J Neurosurg. 2018 Apr 06; 1-5.
    View on PubMed
  7. Alexander MD, Hippe DS, Cooke DL, Hallam DK, Hetts SW, Kim H, Lawton MT, Sekhar LN, Kim LJ, Ghodke BV. Targeted Embolization of Aneurysms Associated With Brain Arteriovenous Malformations at High Risk for Surgical Resection: A Case-Control Study. Neurosurgery. 2018 Mar 01; 82(3):343-349.
    View on PubMed
  8. McGregor HCJ, Surman A, Fernandez A, Saeed M, Wilson M, Hetts S, Conrad M. Pilot Study of the Safety and Efficacy of Gallbladder Cryoablation in a Porcine Model: Midterm Results. J Vasc Interv Radiol. 2018 Mar; 29(3):340-344.
    View on PubMed
  9. Kondapavulur S, Cooke DL, Kao A, Amans MR, Alexander M, Darflinger R, Dowd CF, Higashida RT, Damato B, Halbach VV, Matthay KK, Hetts SW. Estimation of intra-arterial chemotherapy distribution to the retina in pediatric retinoblastoma patients using quantitative digital subtraction angiography. Interv Neuroradiol. 2018 Apr; 24(2):214-219.
    View on PubMed
  10. Yu JF, Nicholson AD, Nelson J, Alexander MD, Tse SH, Hetts SW, Hemphill JC, Kim H, Cooke DL. Predictors of intracranial hemorrhage volume and distribution in brain arteriovenous malformation. Interv Neuroradiol. 2018 Apr; 24(2):183-188.
    View on PubMed
  11. Gandhi CD, Al Mufti F, Singh IP, Abruzzo T, Albani B, Ansari SA, Arthur AS, Bain M, Baxter BW, Bulsara KR, Caplan JM, Chen M, Dabus G, Frei D, Hetts SW, Hussain MS, Jayaraman MV, Kayan Y, Klucznik RP, Lee SK, Mack WJ, Leslie-Mazwi T, McTaggart RA, Meyers PM, Mokin M, Patsalides AT, Prestigiacomo CJ, Pride GL, Starke RM, Sunenshine PJ, Fraser JF. Neuroendovascular management of emergent large vessel occlusion: update on the technical aspects and standards of practice by the Standards and Guidelines Committee of the Society of NeuroInterventional Surgery. J Neurointerv Surg. 2018 Mar; 10(3):315-320.
    View on PubMed
  12. Ammanuel S, Alexander MD, Damato B, Cooke DL, Halbach VV, Amans MR, Dowd CF, Higashida RT, Hetts SW. Improved procedural safety following protocol changes for selective ophthalmic arterial infusion of chemotherapy for treatment of ocular retinoblastoma. Interv Neuroradiol. 2018 Jan 01; 1591019918755088.
    View on PubMed
  13. Meybodi AT, Kim H, Nelson J, Hetts SW, Krings T, terBrugge KG, Faughnan ME, Lawton MT. Surgical Treatment vs Nonsurgical Treatment for Brain Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia: A Retrospective Multicenter Consortium Study. Neurosurgery. 2018 Jan 01; 82(1):35-47.
    View on PubMed
  14. Alexander MD, Rebhun JM, Hetts SW, Amans MR, Settecase F, Darflinger RJ, Dowd CF, Halbach VV, Higashida RT, Cooke DL. Technical factors affecting outcomes following endovascular treatment of posterior circulation atherosclerotic lesions. Surg Neurol Int. 2017; 8:284.
    View on PubMed
  15. Settecase F, McCoy DB, Darflinger R, Alexander MD, Cooke DL, Dowd CF, Hetts SW, Higashida RT, Halbach VV, Amans MR. Improving mechanical thrombectomy time metrics in the angiography suite: Stroke cart, parallel workflows, and conscious sedation. Interv Neuroradiol. 2018 Apr; 24(2):168-177.
    View on PubMed
  16. Leslie-Mazwi T, Chen M, Yi J, Starke RM, Hussain MS, Meyers PM, McTaggart RA, Pride GL, Ansari AS, Abruzzo T, Albani B, Arthur AS, Baxter BW, Bulsara KR, Delgado Almandoz JE, Gandhi CD, Heck D, Hetts SW, Klucznik RP, Jayaraman MV, Lee SK, Mack WJ, Mocco J, Prestigiacomo C, Patsalides A, Rasmussen P, Sunenshine P, Frei D, Fraser JF. Post-thrombectomy management of the ELVO patient: Guidelines from the Society of NeuroInterventional Surgery. J Neurointerv Surg. 2017 12; 9(12):1258-1266.
    View on PubMed
  17. Hetts SW, Yen A, Cooke DL, Nelson J, Jolivalt P, Banaga J, Amans MR, Dowd CF, Higashida RT, Lawton MT, Kim H, Halbach VV. Pial Artery Supply as an Anatomic Risk Factor for Ischemic Stroke in the Treatment of Intracranial Dural Arteriovenous Fistulas. AJNR Am J Neuroradiol. 2017 Dec; 38(12):2315-2320.
    View on PubMed
  18. Yang JK, Cote AM, Jordan CD, Kondapavulur S, Losey AD, McCoy D, Chu A, Yu JF, Moore T, Stillson C, Settecase F, Alexander MD, Nicholson A, Cooke DL, Saeed M, Barry D, Martin AJ, Wilson MW, Hetts SW. Interventional magnetic resonance imaging guided carotid embolectomy using a novel resonant marker catheter: demonstration of preclinical feasibility. Biomed Microdevices. 2017 Sep 25; 19(4):88.
    View on PubMed
  19. Cooke DL, McCoy DB, Halbach VV, Hetts SW, Amans MR, Dowd CF, Higashida RT, Lawson D, Nelson J, Wang CY, Kim H, Werb Z, McCulloch C, Hashimoto T, Su H, Sun Z. Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis. Transl Stroke Res. 2018 Feb; 9(1):20-33.
    View on PubMed
  20. Jovin TG, Saver JL, Ribo M, Pereira V, Furlan A, Bonafe A, Baxter B, Gupta R, Lopes D, Jansen O, Smith W, Gress D, Hetts S, Lewis RJ, Shields R, Berry SM, Graves TL, Malisch T, Rai A, Sheth KN, Liebeskind DS, Nogueira RG. Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods. Int J Stroke. 2017 08; 12(6):641-652.
    View on PubMed

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