University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Steven Hetts, MD

Steven Hetts, MD

Associate Professor in Residence of Radiology and Biomedical Imaging, UCSF

Cancer Center Program Memberships

Neurologic Oncology | Pediatric Malignancies

Research Summary

Steven Hetts, MD, is an Associate Professor of Radiology in Residence at the University of California, San Francisco, and he is Chief of Neuroradiology at the San Francisco General Hospital where he has established a new clinical Interventional Neuroradiology service, providing cutting edge minimally invasive endovascular therapy. Dr. Hetts received his medical degree from Harvard Medical School in Boston, Massachusetts in 2000, and completed a residency in Diagnostic Radiology at UCSF, followed by a fellowship in Diagnostic Neuroradiology and Interventional Neuroradiology from UCSF.

Dr. Hetts is involved in translational research as Co-Director of the Interventional Radiology Laboratory at China Basin, including the conception, performance, and management of research projects translating basic science and engineering research into clinical applicability. One of his projects is Magnetic Catheter Navigation and Microinfarction Evaluation in the Brain and Heart. Dr. Hetts also implements many clinical research projects involving retrospective and prospective patient data. The main focus of his clinical research is endovascular therapy for cerebrovascular disease, spinal vascular disease, and neurooncology.

Education

Harvard College, Boston, MA, AB summa cum laude, 06/1996, Biology
Harvard Medical School, Boston, MA, MD, 06/2000, Medicine
Stanford University Medical Center, Stanford, CA, Internship, 06/2001, Internal Medicine
UCSF Medical Center, San Francisco, CA, Residency, 06/2005, Diagnostic Radiology
UCSF Medical Center, San Francisco, CA, Fellowship, 06/2006, Diagnostic Neuroradiology
UCSF Medical Center, San Francisco, CA, Fellowship, 02/2008, Interventional Neuroradiology


Professional Experience

  • 1991-1992
    Research Associate, Department of Cell Genetics, Genentech, Inc., South San Francisco, CA
  • 1993
    Research Associate, UCSF Department of Radiology
  • 1993
    Research Associate, UCSF Center for Medical Technology Assessment
  • 1994
    Research Associate, The Parkinson’s Institute, Sunnyvale, CA
  • 1994-1996
    Research Associate, Department of Neurology, Children’s Hospital, Boston, MA
  • 1997
    Research Associate, Department of Biology, Tularik, Inc., South San Francisco, CA
  • 2000-2001
    Intern Physician in Internal Medicine, Stanford University Hospital
  • 2001-2005
    Resident Physician in Diagnostic Radiology, UCSF Medical Center
  • 2003-2007
    Co-Investigator, NIH R01 HL076486 (Wilson), UCSF Medical Center 
  • 2005-2006
    Clinical Fellow in Diagnostic Neuroradiology, UCSF Medical Center
  • 2006-2008
    Clinical Fellow in Interventional Neuroradiology, UCSF Medical Center
  • 2008-2013
    Assistant Professor in Residence, Radiology, UCSF
  • 2008-2015
    Chief of Interventional Neuroradiology, San Francisco General Hospital
  • 2008-2015
    Chief of Interventional Neuroradiology, San Francisco VA Medical Center
  • 2008-current
    Attending Interventional Neuroradiologist, UCSF Medical Center
  • 2009-current
    Co-Director, UCSF/SFGH Interventional Radiology Research Laboratory
  • 2009-2010
    Co-Director, Neurovascular/Neurointerventional Research Interest Group, UCSF Radiology
  • 2010-current
    Co-Director, Image-Guided Therapy Specialized Resource Group, UCSF Radiology
  • 2013-current
    Chief Medical Officer and Co-Founder, ChemoFilter, Inc., Hillsborough, CA
  • 2013-current
    Associate Professor in Residence, Radiology, UCSF 
  • 2014-current
    Co-Director, UCSF Hereditary Hemorrhagic Telangiectasia Center of Excellence
  • 2015-current
    Chief of Interventional Neuroradiology, UCSF Benioff Children’s Hospital, UCSF Betty Irene Moore Women’s Hospital, and UCSF Bakar Cancer Hospital

Honors & Awards

  • 1992
    United States Presidential Scholar, highest academic honor for US high school students
  • 1993-1996
    John Harvard Scholarship and Dean’s List, Harvard College
  • 1995
    Phi Beta Kappa, elected in Senior 45, Harvard College
  • 1996
    Biology Undergraduate Honors Thesis, summa cum laude
  • 1997
    Finalist, Rhodes Scholarship, California Nominee to Region VIII Competition
  • 1999
    Aesculapian Club, Harvard Medical School
  • 2001
    Nominee, Resident Teaching Award, Department of Internal Medicine, Stanford Hospital
  • 2002, 2003
    Margulis Society Radiology Resident Research Award
  • 2003
    American Roentgen Ray Society Introduction to Research Program
  • 2004
    International Society for Magnetic Resonance in Medicine Amersham Fellowship
  • 2004
    American Society of Pediatric Neuroradiology Annual Research Award
  • 2005
    Executive Council Award, Residents in Radiology Competition, American Roentgen Ray Society
  • 2010, 2011
    American Society of Neuroradiology, Neuroradiology Research and Education Foundation Scholar Award in Neuroradiology Research
  • 2012
    Visiting Professor, Memorial Sloan Kettering Cancer Center
  • 2015
    Nominee, QB3 Award for Startup of the Year, ChemoFilter
  • 2015
    Fellow, Rosenman Institute, UCSF

Selected Publications

  1. Yang JK, Cote AM, Jordan CD, Kondapavulur S, Losey AD, McCoy D, Chu A, Yu JF, Moore T, Stillson C, Settecase F, Alexander MD, Nicholson A, Cooke DL, Saeed M, Barry D, Martin AJ, Wilson MW, Hetts SW. Interventional magnetic resonance imaging guided carotid embolectomy using a novel resonant marker catheter: demonstration of preclinical feasibility. Biomed Microdevices. 2017 Sep 25; 19(4):88.
    View on PubMed
  2. Cooke DL, McCoy DB, Halbach VV, Hetts SW, Amans MR, Dowd CF, Higashida RT, Lawson D, Nelson J, Wang CY, Kim H, Werb Z, McCulloch C, Hashimoto T, Su H, Sun Z. Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis. Transl Stroke Res. 2017 Sep 13.
    View on PubMed
  3. Alexander MD, Hippe DS, Cooke DL, Hallam DK, Hetts SW, Kim H, Lawton MT, Sekhar LN, Kim LJ, Ghodke BV. Targeted Embolization of Aneurysms Associated With Brain Arteriovenous Malformations at High Risk for Surgical Resection: A Case-Control Study. Neurosurgery. 2017 Apr 13.
    View on PubMed
  4. Zhang X, Martin A, Jordan C, Lillaney P, Losey A, Pang Y, Hu J, Wilson M, Cooke D, Hetts SW. Design of catheter radio frequency coils using coaxial transmission line resonators for interventional neurovascular MR imaging. Quant Imaging Med Surg. 2017 Apr; 7(2):187-194.
    View on PubMed
  5. Kondapavulur S, Cote AM, Neumann KD, Jordan CD, McCoy D, Mabray MC, Liu D, Sze CH, Gautam A, VanBrocklin HF, Wilson M, Hetts SW. Optimization of an endovascular magnetic filter for maximized capture of magnetic nanoparticles. Biomed Microdevices. 2016 Dec; 18(6):109.
    View on PubMed
  6. Aboian MS, Yu JF, Gautam A, Sze CH, Yang JK, Chan J, Lillaney PV, Jordan CD, Oh HJ, Wilson DM, Patel AS, Wilson MW, Hetts SW. In vitro clearance of doxorubicin with a DNA-based filtration device designed for intravascular use with intra-arterial chemotherapy. Biomed Microdevices. 2016 Dec; 18(6):98.
    View on PubMed
  7. Ryu WHA, Avery MB, Dharampal N, Allen IE, Hetts SW. Utility of perfusion imaging in acute stroke treatment: a systematic review and meta-analysis. J Neurointerv Surg. 2017 Oct; 9(10):1012-1016.
    View on PubMed
  8. Lum MA, Martin AJ, Alexander MD, McCoy DB, Cooke DL, Lillaney P, Moftakhar P, Amans MR, Settecase F, Nicholson A, Dowd CF, Halbach VV, Higashida RT, McDermott MW, Saloner D, Hetts SW. Intra-Arterial MR Perfusion Imaging of Meningiomas: Comparison to Digital Subtraction Angiography and Intravenous MR Perfusion Imaging. PLoS One. 2016; 11(11):e0163554.
    View on PubMed
  9. Alexander MD, Nicholson AD, Darflinger RJ, Settecase F, Cooke DL, Dowd CF, Amans MR, Higashida RT, Hetts SW, Halbach VV. Effects on vessel measurement accuracy and subsequent occlusion after calcium channel blocker infusion during treatment of cerebral aneurysms with the Pipeline embolization device. Interv Neuroradiol. 2017 Feb; 23(1):47-51.
    View on PubMed
  10. Pride GL, Fraser JF, Gupta R, Alberts MJ, Rutledge JN, Fowler R, Ansari SA, Abruzzo T, Albani B, Arthur A, Baxter B, Bulsara KR, Chen M, Delgado Almandoz JE, Gandhi CD, Heck D, Hetts SW, Hirsch JA, Hussain MS, Klucznik R, Lee SK, Mack WJ, Leslie-Mazwi T, McTaggart RA, Meyers PM, Mocco J, Prestigiacomo C, Patsalides A, Rasmussen P, Starke RM, Sunenshine P, Frei D, Jayaraman MV. Prehospital care delivery and triage of stroke with emergent large vessel occlusion (ELVO): report of the Standards and Guidelines Committee of the Society of Neurointerventional Surgery. J Neurointerv Surg. 2017 Aug; 9(8):802-812.
    View on PubMed
  11. Hetts SW, Moftakhar P, Maluste N, Fullerton HJ, Cooke DL, Amans MR, Dowd CF, Higashida RT, Halbach VV. Pediatric intracranial dural arteriovenous fistulas: age-related differences in clinical features, angioarchitecture, and treatment outcomes. J Neurosurg Pediatr. 2016 Nov; 18(5):602-610.
    View on PubMed
  12. Chen XC, Oh HJ, Yu JF, Yang JK, Petzetakis N, Patel AS, Hetts SW, Balsara NP. Block Copolymer Membranes for Efficient Capture of a Chemotherapy Drug. ACS Macro Lett. 2016 Aug 16; 5(8):936-941.
    View on PubMed
  13. Turk AS, Johnston SC, Hetts S, Mocco J, English J, Murayama Y, Prestigiacomo CJ, Lopes D, Gobin YP, Carroll K, McDougall C. Geographic Differences in Endovascular Treatment and Retreatment of Cerebral Aneurysms. AJNR Am J Neuroradiol. 2016 Jul 07.
    View on PubMed
  14. De la Huerta I, Seider MI, Hetts SW, Damato BE. Delayed Cerebral Infarction Following Intra-arterial Chemotherapy for Retinoblastoma. JAMA Ophthalmol. 2016 Jun 01; 134(6):712-4.
    View on PubMed
  15. Lavine SD, Cockroft K, Hoh B, Bambakidis N, Khalessi AA, Woo H, Riina H, Siddiqui A, Hirsch JA, Chong W, Rice H, Wenderoth J, Mitchell P, Coulthard A, Signh TJ, Phatorous C, Khangure M, Klurfan P, Ter Brugge K, Iancu D, Gunnarsson T, Jansen O, Muto M, Szikora I, Pierot L, Brouwer P, Gralla J, Renowden S, Andersson T, Fiehler J, Turjman F, White P, Januel AC, Spelle L, Kulcsar Z, Chapot R, Biondi A, Dima S, Taschner C, Szajner M, Krajina A, Sakai N, Matsumaru Y, Yoshimura S, Ezura M, Fujinaka T, Iihara K, Ishii A, Higashi T, Hirohata M, Hyodo A, Ito Y, Kawanishi M, Kiyosue H, Kobayashi E, Kobayashi S, Kuwayama N, Matsumoto Y, Miyachi S, Murayama Y, Nagata I, Nakahara I, Nemoto S, Niimi Y, Oishi H, Satomi J, Satow T, Sugiu K, Tanaka M, Terada T, Yamagami H, Diaz O, Lylyk P, Jayaraman MV, Patsalides A, Gandhi CD, Lee SK, Abruzzo T, Albani B, Ansari SA, Arthur AS, Baxter BW, Bulsara KR, Chen M, Almandoz JED, Fraser JF, Heck DV, Hetts SW, Hussain MS, Klucznik RP, Leslie-Mawzi TM, Mack WJ, McTaggart RA, Meyers PM, Mocco J, Prestigiacomo CJ, Pride GL, Rasmussen PA, Starke RM, Sunenshine PJ, Tarr RW, Frei DF, Ribo M, Nogueira RG, Zaidat OO, Jovin T, Linfante I, Yavagal D, Liebeskind D, Novakovic R, Pongpech S, Rodesch G, Soderman M, Taylor A, Krings T, Orbach D, Picard L, Suh DC, Zhang HQ. Training guidelines for endovascular stroke intervention: an international multi-society consensus document. Neuroradiology. 2016 Jun; 58(6):537-541.
    View on PubMed
  16. McGregor HC, Saeed M, Surman A, Ehman EC, Hetts SW, Wilson MW, Conrad MB. Gallbladder Cryoablation: Proof of Concept in a Swine Model for a Percutaneous Alternative to Cholecystectomy. Cardiovasc Intervent Radiol. 2016 Jul; 39(7):1031-5.
    View on PubMed
  17. Alexander MD, Cooke DL, Hallam DK, Kim H, Hetts SW, Ghodke BV. Less can be more: Targeted embolization of aneurysms associated with arteriovenous malformations unsuitable for surgical resection. Interv Neuroradiol. 2016 Aug; 22(4):445-51.
    View on PubMed
  18. Saeed M, Krug R, Do L, Hetts SW, Wilson MW. Renal ablation using magnetic resonance-guided high intensity focused ultrasound: Magnetic resonance imaging and histopathology assessment. World J Radiol. 2016 Mar 28; 8(3):298-307.
    View on PubMed
  19. Lillaney PV, Yang JK, Losey AD, Martin AJ, Cooke DL, Thorne BR, Barry DC, Chu A, Stillson C, Do L, Arenson RL, Saeed M, Wilson MW, Hetts SW. Endovascular MR-guided Renal Embolization by Using a Magnetically Assisted Remote-controlled Catheter System. Radiology. 2016 Oct; 281(1):219-28.
    View on PubMed
  20. Lavine SD, Cockroft K, Hoh B, Bambakidis N, Khalessi AA, Woo H, Riina H, Siddiqui A, Hirsch JA, Chong W, Rice H, Wenderoth J, Mitchell P, Coulthard A, Signh TJ, Phatorous C, Khangure M, Klurfan P, Ter Brugge K, Iancu D, Gunnarsson T, Jansen O, Muto M, Szikora I, Pierot L, Brouwer P, Gralla J, Renowden S, Andersson T, Fiehler J, Turjman F, White P, Januel AC, Spelle L, Kulcsar Z, Chapot R, Biondi A, Dima S, Taschner C, Szajner M, Krajina A, Sakai N, Matsumaru Y, Yoshimura S, Diaz O, Lylyk P, Jayaraman MV, Patsalides A, Gandhi CD, Lee SK, Abruzzo T, Albani B, Ansari SA, Arthur AS, Baxter BW, Bulsara KR, Chen M, Almandoz JE, Fraser JF, Heck DV, Hetts SW, Hussain MS, Klucznik RP, Leslie-Mawzi TM, Mack WJ, McTaggart RA, Meyers PM, Mocco J, Prestigiacomo CJ, Pride GL, Rasmussen PA, Starke RM, Sunenshine PJ, Tarr RW, Frei DF, Ribo M, Nogueira RG, Zaidat OO, Jovin T, Linfante I, Yavagal D, Liebeskind D, Novakovic R, Pongpech S, Rodesch G, Soderman M, Ter Brugge K, Taylor A, Krings T, Orbach D, Biondi A, Picard L, Suh DC, Tanaka M, Zhang HQ. Training Guidelines for Endovascular Stroke Intervention: An International Multi-Society Consensus Document. Interv Neurol. 2016 Jun; 5(1-2):51-6.
    View on PubMed

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