Karla Kerlikowske, MD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Karla Kerlikowske, MD

Professor, Departments of Medicine and Epidemiology/Biostatistics, UCSF

karla.kerlikowske@ucsf.edu

Phone: (415) 750-2093 (voice)
VAMC 111A1, San Francisco, CA 94143

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Cancer Center Membership

Program Member ยป Breast Oncology

Research Summary

I have published widely on breast imaging and the epidemiology of invasive breast cancer, DCIS and breast density, and risk prediction models for invasive breast cancer. I have extensive experience, expertise, and leadership in large-scale multi-disciplinary NIH-funded efforts of breast cancer screening, risk factors, and risk, including the U01 San Francisco Mammography Registry (SFMR), P50 UCSF Breast Cancer SPORE, P01 Breast Density Program Project, and the Breast Cancer Surveillance Consortium (BCSC) P01 Risk-based Breast Cancer Screening Program Project. As PI or co-PI on several these grants, I have developed cohorts of women at risk for invasive breast cancer and DCIS and developed comprehensive databases that include breast imaging, pathologic, clinical, biomarker, and risk factor data, as well as follow-up for subsequent disease and death. In addition, I have successfully administered projects (e.g., staffing, research protections, budget), collaborated with other researchers, and produced many peer-reviewed publications from each project. I have a demonstrated record of successful and productive research projects in areas of high relevance for breast cancer screening, breast density, DCIS, and risk prediction.

Education

Michigan State University, East Lansing, BS, 1978, Medical Technology
University of California, Berkeley, MS, 1984, Nutrition
University of California San Francisco, MD, 1988, Medicine


Professional Experience

  • 1988-89
    Medicine Internship, University of California San Francisco, San Francisco, CA
  • 1989-91
    Primary Care Medicine Residency, University of California San Francisco, San Francisco, CA
  • 1991-93
    Fellow in General Internal Medicine, Veterans Affairs Medical Center, San Francisco, CA
  • 1991-93
    Clinical Instructor, Assistant Physician, UCSF Department of Medicine, San Francisco, CA
  • 1993-1999
    Associate Director, Women's Clinic, Veterans Affairs Medical Center, San Francisco, CA
  • 1999-present
    Director, Women's Clinic, Veterans Affairs Medical Center, San Francisco, CA
  • 1994-present
    Assistant Professor In Residence, UCSF Department of Medicine, San Francisco, CA
  • 1994-present
    Assistant Professor In Residence, UCSF Department of Epidemiology & Biostatistics, San Francisco, CA
  • 2000-present
    Associate Professor, In Residence, Department of Medicine, Univ. of California, San Francisco
  • 2000-present
    Associate Professor, In Residence, Department of Epidemiology & Biostatistics, Univ. of California, San Francisco
  • 2000-present
    Professor, In Residence, Department of Epidemiology & Biostatistics, Univ. of California, San Francisco

Honors & Awards

  • 1975
    Tower Guard Award for Scholastic Achievement
  • 1975-77
    Honors College, Michigan State University
  • 1978
    Magna cum laude, Michigan State University
  • 1986
    Student Summer Research Fellowship, UCSF
  • 1987
    Alpha Omega Alpha
  • 1994-96
    American Cancer Society Award for Primary Care Physicians

Selected Publications

  1. Progress Toward Consensus on Breast Cancer Screening Guidelines and Reducing Screening Harms. JAMA Intern Med. 2015 Dec 1; 175(12):1970-1.
    View on PubMed
  2. Increased Risk of Developing Breast Cancer after a False-Positive Screening Mammogram. Cancer Epidemiol Biomarkers Prev. 2015 Dec; 24(12):1882-9.
    View on PubMed
  3. Diagnostic Accuracy of Digital Screening Mammography With and Without Computer-Aided Detection. JAMA Intern Med. 2015 Nov 1; 175(11):1828-37.
    View on PubMed
  4. Breast Tumor Prognostic Characteristics and Biennial vs Annual Mammography, Age, and Menopausal Status. JAMA Oncol. 2015 Nov 1; 1(8):1069-77.
    View on PubMed
  5. Factors Associated with Preoperative Magnetic Resonance Imaging Use among Medicare Beneficiaries with Nonmetastatic Breast Cancer. Breast J. 2016 Jan; 22(1):24-34.
    View on PubMed
  6. Impact of a primary care based intervention on breast cancer knowledge, risk perception and concern: A randomized, controlled trial. Breast. 2015 Dec; 24(6):758-66.
    View on PubMed
  7. Breast Cancer Characteristics Associated With Digital Versus Film-Screen Mammography for Screen-Detected and Interval Cancers. AJR Am J Roentgenol. 2015 Sep; 205(3):676-84.
    View on PubMed
  8. The Effect of Change in Body Mass Index on Volumetric Measures of Mammographic Density. Cancer Epidemiol Biomarkers Prev. 2015 Nov; 24(11):1724-30.
    View on PubMed
  9. Breast Density and Benign Breast Disease: Risk Assessment to Identify Women at High Risk of Breast Cancer. J Clin Oncol. 2015 Oct 1; 33(28):3137-43.
    View on PubMed
  10. Patient and Radiologist Characteristics Associated With Accuracy of Two Types of Diagnostic Mammograms. AJR Am J Roentgenol. 2015 Aug; 205(2):456-63.
    View on PubMed
  11. Association of tamoxifen use and ovarian function in patients with invasive or pre-invasive breast cancer. Breast Cancer Res Treat. 2015 Aug; 153(1):173-81.
    View on PubMed
  12. Comparing sensitivity and specificity of screening mammography in the United States and Denmark. Int J Cancer. 2015 Nov 1; 137(9):2198-207.
    View on PubMed
  13. Comparison of cumulative false-positive risk of screening mammography in the United States and Denmark. Cancer Epidemiol. 2015 Aug; 39(4):656-63.
    View on PubMed
  14. Identifying women with dense breasts at high risk for interval cancer: a cohort study. Ann Intern Med. 2015 May 19; 162(10):673-81.
    View on PubMed
  15. Radiographers supporting radiologists in the interpretation of screening mammography: a viable strategy to meet the shortage in the number of radiologists. BMC Cancer. 2015; 15(1):410.
    View on PubMed
  16. Variation in Breast Cancer-Risk Factor Associations by Method of Detection: Results From a Series of Case-Control Studies. Am J Epidemiol. 2015 Jun 15; 181(12):956-69.
    View on PubMed
  17. One versus Two Breast Density Measures to Predict 5- and 10-Year Breast Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2015 Jun; 24(6):889-97.
    View on PubMed
  18. The contributions of breast density and common genetic variation to breast cancer risk. J Natl Cancer Inst. 2015 May; 107(5).
    View on PubMed
  19. Dense and nondense mammographic area and risk of breast cancer by age and tumor characteristics. Cancer Epidemiol Biomarkers Prev. 2015 May; 24(5):798-809.
    View on PubMed
  20. Benefits, harms, and cost-effectiveness of supplemental ultrasonography screening for women with dense breasts. Ann Intern Med. 2015 Feb 3; 162(3):157-66.
    View on PubMed

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