Kimberly Kirkwood, MD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Kimberly Kirkwood, MD

Professor, Department of Surgery, UCSF

Phone: (415) 514-1964
Box 0790, UCSF
San Francisco, CA 94143-0790

UCSF Profiles | Physician Referral Directory

Cancer Center Membership

Associate Member ยป Cancer Genetics

Education

Reed College, Portland, OR, B.A., 1977-1981, Biology
University of Pennsylvania School of Medicine, Philadelphia, PA, M.D., 1981-1985, Medicine


Professional Experience

  • 1985-1988
    Intern/Resident, Massachusetts General Hospital, Boston, MA
  • 1988-1991
    Research Fellow, UCLA School of Medicine, Los Angeles, CA
  • 1991-1993
    Resident/Chief, Massachusetts General Hospital, Boston, MA
  • 1993-1994
    Chief of the General Surgical Teaching Service, Massachusetts General Hospital, Boston, MA
  • 1994-1994
    Attending in Trauma and General Surgery, Massachusetts General Hospital, Boston, MA
  • 1994-present
    Attending in General and Laproscopic surgery, UCSF Medical Center, San Francisco, CA
  • 1994-2000
    Assistant Professor of Surgery in Residence, UCSF School of Medicine, San Francisco, CA
  • 2000-2008
    Associate Professor of Surgery in Residence, UCSF School of Medicine, San Francisco, CA
  • 2008-present
    Professor of Surgery, UCSF Medical Center, San Francisco, CA

Honors & Awards

  • 1981
    Phi Beta Kappa National Honor Society
  • 1981
    Walter Croll Scholarship, University of Pennsylvania School of Medicine
  • 1983-85
    President, Alpha Omega Alpha National Medical Honor Society, University of Pennsylvania Chapter
  • 1989-90
    Claude E. Welch Research Fellowship Award, Department of Surgery, Mass General Hospital
  • 1990-91
    Claude E. Welch Research Fellowship Award, Department of Surgery, Mass General Hospital
  • 1995-96
    Nominated, Kaiser Award for Excellence in Teaching, UCSF School of Medicine
  • 1996-97
    Excellence in Teaching, UCSF Department of Surgery Chief Residents
  • 1998
    Clinical Teaching Award, UCSF School of Medicine, Class of 1998
  • 1999
    Nominated, Kaiser Award for Excellence in Teaching, Medical Students
  • 2001
    Excellence in Teaching Award, UCSF Department of Surgery Residents
  • 2004
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2004
    Kaiser Award for Excellence in Teaching Nomination, UCSF School of Medicine
  • 2008
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2009
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2010
    AGA Student Abstract Prize (Victoria Lyo), American Gastroenterological Association (AGA) Foundation
  • 2010
    Kaiser Award for Excellence in Teaching Nomination, UCSF School of Medicine
  • 2010
    Pancreas Club Warren Award (Victoria Lyo), Pancreas Club
  • 2010
    Howard Hughes Research Fellowship (Victoria Lyo), Howard Hughes Medical Institute
  • 2012
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2013
    Excellence in Teaching Award, UCSF School of Medicine, Surgical Clerkship
  • 2014
    Excellence in Teaching Award, UCSF Department of Surgery Chief Residents
  • 2015
    Excellence in Teaching Award, Inaugural, UCSF Department of Surgery Junior Residents

  • Ongoing Research Support

    • 7/2013-6/2014
      CTSI Phase 1, TI Catalyst: Early Diagnosis of Pancreatic Cancer Using a Non-Invasive Imaging Tool
    • 7/2013-6/2014
      UCSF RAP Cancer Pilot: Non-Invasive Imaging of Proteolytic Activity in the Pancreas: Towards Early Diagnosis of Pancreatic Cancer
    • 04/01/03-03/31/14
      R01 DK46285 (no cost extension) NIH: Neural Regulation of Pancreatic Function
      The major goals of this project are to examine the role of proteases, sensory nerves, tachykinins, ion channels, and neurokinin receptors in pancreatic inflammation and pain.

    Past Research Support (Selected)

    • 07/01/2009-06/30/12
      2T32DK07573-21 NIH: GI Training Grant
      The goal of this project is to provide 2 years of independent research training to fellows with academic career goals in the field of gastrointestinal surgery. Dr. Kirkwood has mentored 8 surgical research fellows in 17 years.
    • 02/01/10-01/31/11
      3R01DK046285-10S1 NIH: Neural Regulation of Pancreatic Function (Recovery Act Administrative Supplement)
      The purpose of this study is to further to examine the role of proteases, sensory nerves, tachykinins, ion channels, and neurokinin receptors in pancreatic inflammation and pain.
    • 07/01/2010-06/30/11
      Foundation - Greenwall Foundation (Co PI: Kirkwood, Lo) Ethics of Informed Consent for Innovative surgical procedures
      The purpose of this study is to develop an understanding of the ethical and legal issues that surround informed consent for innovative surgical procedures.
    • 04/01/08-03/31/13
      2 R01 DK046285-14 NIH: Neural Regulation of Pancreatic Function
      The major goals of this project are to examine the role of proteases, sensory nerves, tachykinins, ion channels, and neurokinin receptors in pancreatic inflammation and pain.

Selected Publications

  1. Wang J, Paris PL, Chen J, Ngo V, Yao H, Frazier ML, Killary AM, Liu CG, Liang H, Mathy C, Bondada S, Kirkwood K, Sen S. Next generation sequencing of pancreatic cyst fluid microRNAs from low grade-benign and high grade-invasive lesions. Cancer Lett. 2015 Jan 28; 356(2 Pt B):404-9.
    View on PubMed
  2. Cattaruzza F, Amadesi S, Carlsson JF, Murphy JE, Lyo V, Kirkwood K, Cottrell GS, Bogyo M, Knecht W, Bunnett NW. Serine proteases and protease-activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants. Br J Pharmacol. 2014 Aug; 171(16):3814-26.
    View on PubMed
  3. Cattaruzza F, Johnson C, Leggit A, Grady E, Schenk AK, Cevikbas F, Cedron W, Bondada S, Kirkwood R, Malone B, Steinhoff M, Bunnett N, Kirkwood KS. Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice. Am J Physiol Gastrointest Liver Physiol. 2013 Jun 1; 304(11):G1002-12.
    View on PubMed
  4. Lee Char SJ, Hills NK, Lo B, Kirkwood KS. Informed consent for innovative surgery: a survey of patients and surgeons. Surgery. 2013 Apr; 153(4):473-80.
    View on PubMed
  5. Lyo V, Cattaruzza F, Kim TN, Walker AW, Paulick M, Cox D, Cloyd J, Buxbaum J, Ostroff J, Bogyo M, Grady EF, Bunnett NW, Kirkwood KS. Active cathepsins B, L, and S in murine and human pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2012 Oct 15; 303(8):G894-903.
    View on PubMed
  6. Minter RM, Angelos P, Coimbra R, Dale P, de Vera ME, Hardacre J, Hawkins W, Kirkwood K, Matthews JB, McLoughlin J, Peralta E, Schmidt M, Zhou W, Schwarze ML. Ethical management of conflict of interest: proposed standards for academic surgical societies. J Am Coll Surg. 2011 Nov; 213(5):677-82.
    View on PubMed
  7. Ceppa EP, Lyo V, Grady EF, Knecht W, Grahn S, Peterson A, Bunnett NW, Kirkwood KS, Cattaruzza F. Serine proteases mediate inflammatory pain in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2011 Jun; 300(6):G1033-42.
    View on PubMed
  8. Ceppa E, Cattaruzza F, Lyo V, Amadesi S, Pelayo JC, Poole DP, Vaksman N, Liedtke W, Cohen DM, Grady EF, Bunnett NW, Kirkwood KS. Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice. Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3):G556-71.
    View on PubMed
  9. Maa J, Carter JT, Kirkwood KS, Gosnell JE, Wang V, McDermott MW. Technique for placement of lumboperitoneal catheters using a combined laparoscopic procedure with the Seldinger micropuncture technique. J Am Coll Surg. 2008 Jul; 207(1):e5-7.
    View on PubMed
  10. Finzi L, Barbu V, Burgel PR, Mergey M, Kirkwood KS, Wick EC, Scoazec JY, Peschaud F, Paye F, Nadel JA, Housset C. MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder. Am J Pathol. 2006 Dec; 169(6):2031-41.
    View on PubMed
  11. Grahn SW, Alvarez J, Kirkwood K. Trends in laparoscopic splenectomy for massive splenomegaly. Arch Surg. 2006 Aug; 141(8):755-61; discussion 761-2.
    View on PubMed
  12. Wick EC, Pikios S, Grady EF, Kirkwood KS. Calcitonin gene-related peptide partially mediates nociception in acute experimental pancreatitis. Surgery. 2006 Feb; 139(2):197-201.
    View on PubMed
  13. Wick EC, Hoge SG, Grahn SW, Kim E, Divino LA, Grady EF, Bunnett NW, Kirkwood KS. Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2006 May; 290(5):G959-69.
    View on PubMed
  14. Day AL, Wick E, Jordan TH, Jaffray CE, Bunnett NW, Grady EF, Kirkwood KS. Neutral endopeptidase determines the severity of pancreatitis-associated lung injury. J Surg Res. 2005 Sep; 128(1):21-7.
    View on PubMed
  15. Hutter MM, Wick EC, Day AL, Maa J, Zerega EC, Richmond AC, Jordan TH, Grady EF, Mulvihill SJ, Bunnett NW, Kirkwood KS. Transient receptor potential vanilloid (TRPV-1) promotes neurogenic inflammation in the pancreas via activation of the neurokinin-1 receptor (NK-1R). Pancreas. 2005 Apr; 30(3):260-5.
    View on PubMed
  16. Lu EJ, Curet MJ, El-Sayed YY, Kirkwood KS. Medical versus surgical management of biliary tract disease in pregnancy. Am J Surg. 2004 Dec; 188(6):755-9.
    View on PubMed
  17. Lightner AM, Glasgow RE, Jordan TH, Krassner AD, Way LW, Mulvihill SJ, Kirkwood KS. Pancreatic resection in the elderly. J Am Coll Surg. 2004 May; 198(5):697-706.
    View on PubMed
  18. Kim EH, Hoge SG, Lightner AM, Grady EF, Coelho AM, Kirkwood KS. Activation of nociceptive neurons in T9 and T10 in cerulein pancreatitis. J Surg Res. 2004 Apr; 117(2):195-201.
    View on PubMed
  19. Kerlan RK, LaBerge JM, Wilson MW, Gordon RL, Kirkwood K, Sawhney R. SIR 2003 film panel case 5: massive hemorrhage from portal vein disruption. J Vasc Interv Radiol. 2003 Jun; 14(6):797-802.
    View on PubMed
  20. Abedin MZ, Narins SC, Park EH, Smith PR, Kirkwood KS. Lovastatin alters biliary lipid composition and dissolves gallstones: a long-term study in prairie dogs. Dig Dis Sci. 2002 Oct; 47(10):2192-210.
    View on PubMed

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