Thomas Kornberg, PhD


Professor, Department of Biochemistry and Biophysics, UCSF

Phone: (415) 476-8821 (voice)
Box 2711, UCSF
San Francisco, CA 94143-2711

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Additional Websites


Juilliard School of Music
Columbia College, B.A., 1970, Biology
Columbia University, Ph.D., 1973, Biochemistry
Princeton University, postdoctoral, 1973-1975, Biochemistry
Cambridge MRC Laboratory of Molecular Biology, postdoctoral, 1975-1976, Developmental Genetics

Professional Experience

  • 1976-1977
    Assistant Professor, Molecular Biology Institute and Department of Chemistry, University of California, Los Angeles
  • 1986-present
    Assistant Professor, Associate Professor, Professor, Department of Biochemistry and Biophysics, University of California San Francisco

Honors & Awards

  • 1978
    American Cancer Society Career Development Award
  • 2001
    Member, American Academy of Arts and Sciences

Selected Publications

  1. Roy S, Kornberg TB. Paracrine signaling mediated at cell-cell contacts. Bioessays. 2015 Jan; 37(1):25-33.
    View on PubMed
  2. Kornberg TB. Cytonemes and the dispersion of morphogens. Wiley Interdiscip Rev Dev Biol. 2014 Nov; 3(6):445-63.
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  3. Kornberg TB. The contrasting roles of primary cilia and cytonemes in Hh signaling. Dev Biol. 2014 Oct 1; 394(1):1-5.
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  4. Guerrero I, Kornberg TB. Hedgehog and its circuitous journey from producing to target cells. Semin Cell Dev Biol. 2014 Sep; 33:52-62.
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  5. Yu D, Gustafson WC, Han C, Lafaye C, Noirclerc-Savoye M, Ge WP, Thayer DA, Huang H, Kornberg TB, Royant A, Jan LY, Jan YN, Weiss WA, Shu X. An improved monomeric infrared fluorescent protein for neuronal and tumour brain imaging. Nat Commun. 2014; 5:3626.
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  6. Kornberg TB, Roy S. Communicating by touch--neurons are not alone. Trends Cell Biol. 2014 Jun; 24(6):370-6.
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  7. Kornberg TB, Roy S. Cytonemes as specialized signaling filopodia. Development. 2014 Feb; 141(4):729-36.
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  8. Roy S, Huang H, Liu S, Kornberg TB. Cytoneme-mediated contact-dependent transport of the Drosophila decapentaplegic signaling protein. Science. 2014 Feb 21; 343(6173):1244624.
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  9. Ibrahim DM, Biehs B, Kornberg TB, Klebes A. Microarray comparison of anterior and posterior Drosophila wing imaginal disc cells identifies novel wing genes. G3 (Bethesda). 2013 Aug; 3(8):1353-62.
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  10. Kornberg TB. Cytonemes extend their reach. EMBO J. 2013 Jun 12; 32(12):1658-9.
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  11. Ali-Murthy Z, Lott SE, Eisen MB, Kornberg TB. An essential role for zygotic expression in the pre-cellular Drosophila embryo. PLoS Genet. 2013 Apr; 9(4):e1003428.
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  12. Kornberg TB. The imperatives of context and contour for morphogen dispersion. Biophys J. 2012 Dec 5; 103(11):2252-6.
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  13. Casso DJ, Liu S, Biehs B, Kornberg TB. Expression and characterization of Drosophila signal peptide peptidase-like (sppL), a gene that encodes an intramembrane protease. PLoS One. 2012; 7(3):e33827.
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  14. Roy S, Kornberg TB. Direct delivery mechanisms of morphogen dispersion. Sci Signal. 2011; 4(200):pt8.
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  15. Kornberg TB. Barcoding Hedgehog for intracellular transport. Sci Signal. 2011; 4(200):pe44.
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  16. Roy S, Hsiung F, Kornberg TB. Specificity of Drosophila cytonemes for distinct signaling pathways. Science. 2011 Apr 15; 332(6027):354-8.
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  17. Casso DJ, Biehs B, Kornberg TB. A novel interaction between hedgehog and Notch promotes proliferation at the anterior-posterior organizer of the Drosophila wing. Genetics. 2011 Feb; 187(2):485-99.
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  18. Biehs B, Kechris K, Liu S, Kornberg TB. Hedgehog targets in the Drosophila embryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling. Development. 2010 Nov; 137(22):3887-98.
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  19. Kechris KJ, Biehs B, Kornberg TB. Generalizing moving averages for tiling arrays using combined p-value statistics. Stat Appl Genet Mol Biol. 2010; 9:Article29.
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  20. Baig J, Chanut F, Kornberg TB, Klebes A. The chromatin-remodeling protein Osa interacts with CyclinE in Drosophila eye imaginal discs. Genetics. 2010 Mar; 184(3):731-44.
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