Professor, Department of Biochemistry and Biophysics, UCSF
Additional Websites
Education
Juilliard School of Music
Columbia College, B.A., 1970, Biology
Columbia University, Ph.D., 1973, Biochemistry
Princeton University, postdoctoral, 1973-1975, Biochemistry
Cambridge MRC Laboratory of Molecular Biology, postdoctoral, 1975-1976, Developmental Genetics
Professional Experience
- 1976-1977
Assistant Professor, Molecular Biology Institute and Department of Chemistry, University of California, Los Angeles
- 1986-present
Assistant Professor, Associate Professor, Professor, Department of Biochemistry and Biophysics, University of California San Francisco
Honors & Awards
- 1978
American Cancer Society Career Development Award - 2001
Member, American Academy of Arts and Sciences
Selected Publications
- Ibrahim DM, Biehs B, Kornberg TB, Klebes A. Microarray comparison of anterior and posterior Drosophila wing imaginal disc cells identifies novel wing genes. G3 (Bethesda). 2013; 3(8):1353-62.
View on PubMed - Kornberg TB. Cytonemes extend their reach. EMBO J. 2013 Jun 12; 32(12):1658-9.
View on PubMed - Ali-Murthy Z, Lott SE, Eisen MB, Kornberg TB. An essential role for zygotic expression in the pre-cellular Drosophila embryo. PLoS Genet. 2013 Apr; 9(4):e1003428.
View on PubMed - Kornberg TB. The imperatives of context and contour for morphogen dispersion. Biophys J. 2012 Dec 5; 103(11):2252-6.
View on PubMed - Casso DJ, Liu S, Biehs B, Kornberg TB. Expression and characterization of Drosophila signal peptide peptidase-like (sppL), a gene that encodes an intramembrane protease. PLoS One. 2012; 7(3):e33827.
View on PubMed - Roy S, Kornberg TB. Direct delivery mechanisms of morphogen dispersion. Sci Signal. 2011; 4(200):pt8.
View on PubMed - Kornberg TB. Barcoding Hedgehog for intracellular transport. Sci Signal. 2011; 4(200):pe44.
View on PubMed - Roy S, Hsiung F, Kornberg TB. Specificity of Drosophila cytonemes for distinct signaling pathways. Science. 2011 Apr 15; 332(6027):354-8.
View on PubMed - Casso DJ, Biehs B, Kornberg TB. A novel interaction between hedgehog and Notch promotes proliferation at the anterior-posterior organizer of the Drosophila wing. Genetics. 2011 Feb; 187(2):485-99.
View on PubMed - Biehs B, Kechris K, Liu S, Kornberg TB. Hedgehog targets in the Drosophila embryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling. Development. 2010 Nov; 137(22):3887-98.
View on PubMed - Kechris KJ, Biehs B, Kornberg TB. Generalizing moving averages for tiling arrays using combined p-value statistics. Stat Appl Genet Mol Biol. 2010; 9(1):Article29.
View on PubMed - Baig J, Chanut F, Kornberg TB, Klebes A. The chromatin-remodeling protein Osa interacts with CyclinE in Drosophila eye imaginal discs. Genetics. 2010 Mar; 184(3):731-44.
View on PubMed - Guha A, Lin L, Kornberg TB. Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis. Dev Biol. 2009 Nov 15; 335(2):317-26.
View on PubMed - Kawamura S, Hervold K, Ramirez-Weber FA, Kornberg TB. Two patched protein subtypes and a conserved domain of group I proteins that regulates turnover. J Biol Chem. 2008 Nov 7; 283(45):30964-9.
View on PubMed - Guha A, Lin L, Kornberg TB. Organ renewal and cell divisions by differentiated cells in Drosophila. Proc Natl Acad Sci U S A. 2008 Aug 5; 105(31):10832-6.
View on PubMed - Casso DJ, Liu S, Iwaki DD, Ogden SK, Kornberg TB. A screen for modifiers of hedgehog signaling in Drosophila melanogaster identifies swm and mts. Genetics. 2008 Mar; 178(3):1399-413.
View on PubMed - Klebes A, Kornberg TB. Linear RNA amplification for the production of microarray hybridization probes. Methods Mol Biol. 2008; 420:303-17.
View on PubMed - Kornberg TB, Guha A. Understanding morphogen gradients: a problem of dispersion and containment. Curr Opin Genet Dev. 2007 Aug; 17(4):264-71.
View on PubMed - Lu X, Liu S, Kornberg TB. The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover. Genes Dev. 2006 Sep 15; 20(18):2539-51.
View on PubMed - Ogden SK, Casso DJ, Ascano M, Yore MM, Kornberg TB, Robbins DJ. Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms. J Biol Chem. 2006 Mar 17; 281(11):7237-43.
View on PubMed
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