Thomas Kornberg, PhD

Education

Professional Experience

• 1976-1977
  Assistant Professor, Molecular Biology Institute and Department of Chemistry, University of California, Los Angeles
• 1986-present
  Assistant Professor, Associate Professor, Professor, Department of Biochemistry and Biophysics, University of California San Francisco

Honors & Awards

• 1978
  American Cancer Society Career Development Award
• 2001
  Member, American Academy of Arts and Sciences

Selected Publications

1. Zhang Q, Schepis A, Huang H, Yang J, Ma W, Torra J, Zhang SQ, Yang L, Wu H, Nonell S, Dong Z, Kornberg TB, Coughlin SR, Shu X. Designing a green fluorogenic protease reporter by flipping a beta strand of GFP for imaging apoptosis in animals. J Am Chem Soc. 2019 Mar 01.
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2. Huang H, Liu S, Kornberg TB. Glutamate signaling at cytoneme synapses. Science. 2019 03 01; 363(6430):948-955.
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3. Llano E, Pendás AM, Aza-Blanc P, Kornberg TB, López-Otín C. Withdrawal: Dm1-MMP, a matrix metalloproteinase from Drosophila with a potential role in extracellular matrix remodeling during neural development. J Biol Chem. 2019 Jan 25; 294(4):1428.
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4. Zhang Q, Huang H, Zhang L, Wu R, Chung CI, Zhang SQ, Torra J, Schepis A, Coughlin SR, Kornberg TB, Shu X. Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. Mol Cell. 2018 01 18; 69(2):347.
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5. Zhang Q, Huang H, Zhang L, Wu R, Chung CI, Zhang SQ, Torra J, Schepis A, Coughlin SR, Kornberg TB, Shu X. Visualizing Dynamics of Cell Signaling In Vivo with a Phase Separation-Based Kinase Reporter. Mol Cell. 2018 01 18; 69(2):334-346.e4.
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6. Kornberg TB. Scripting a place in time. Dev Biol. 2019 Mar 01; 447(1):24-27.
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7. Chen W, Huang H, Hatori R, Kornberg TB. Essential basal cytonemes take up Hedgehog in the Drosophila wing imaginal disc. Development. 2017 09 01; 144(17):3134-3144.
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8. Kashima R, Redmond PL, Ghatpande P, Roy S, Kornberg TB, Hanke T, Knapp S, Lagna G, Hata A. Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome. Sci Signal. 2017 May 02; 10(477).
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9. Kornberg TB. Macrophages Help Cells Connect to Pattern Zebrafish Stripes. Dev Cell. 2017 03 27; 40(6):520-521.
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10. Ali-Murthy Z, Kornberg TB. Correction: Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm. Elife. 2017 03 15; 6.
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11. Kornberg TB. Distributing signaling proteins in space and time: the province of cytonemes. Curr Opin Genet Dev. 2017 Aug; 45:22-27.
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12. Huang H, Kornberg TB. Cells must express components of the planar cell polarity system and extracellular matrix to support cytonemes. Elife. 2016 09 03; 5.
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13. Kashima R, Roy S, Ascano M, Martinez-Cerdeno V, Ariza-Torres J, Kim S, Louie J, Lu Y, Leyton P, Bloch KD, Kornberg TB, Hagerman PJ, Hagerman R, Lagna G, Hata A. Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome. Sci Signal. 2016 06 07; 9(431):ra58.
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14. Ali-Murthy Z, Kornberg TB. Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm. Elife. 2016 Feb 17; 5.
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15. Kornberg TB. A Path to Pattern. Curr Top Dev Biol. 2016; 116:551-67.
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16. Rao PR, Lin L, Huang H, Guha A, Roy S, Kornberg TB. Developmental compartments in the larval trachea of Drosophila. Elife. 2015 Oct 22; 4.
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17. Kornberg TB, Gilboa L. Developmental biology: Nanotubes in the niche. Nature. 2015 Jul 16; 523(7560):292-3.
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18. Yu D, Baird MA, Allen JR, Howe ES, Klassen MP, Reade A, Makhijani K, Song Y, Liu S, Murthy Z, Zhang SQ, Weiner OD, Kornberg TB, Jan YN, Davidson MW, Shu X. A naturally monomeric infrared fluorescent protein for protein labeling in vivo. Nat Methods. 2015 Aug; 12(8):763-5.
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19. Huang H, Kornberg TB. Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium. Elife. 2015 May 07; 4:e06114.
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20. Roy S, Kornberg TB. Paracrine signaling mediated at cell-cell contacts. Bioessays. 2015 Jan; 37(1):25-33.
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