Andrew D. Leavitt, MD


Professor, Departments of Laboratory Medicine and Medicine (Div. of Hematology/Oncology), UCSF

Phone: (415) 514-3432, 476-4217 (voice)
Box 0100, UCSF
San Francisco, CA 94143-0100

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University of Michigan, Ann Arbor, B.S., 1979, Zoology
Harvard Medical School, M.D., 1984, Medicine

Professional Experience

  • 1982-1984
    Medical School Research Fellowship, Harvard Medical School, Department of Pediatric Hematology & Oncology (Laboratory of Dr. Robert Garcea; Project: Expression cloning, purification, and characterization of Polyoma major capsid protein, VP1)
  • 1984-1987
    Intern and Resident, Department of Internal Medicine, University of Michigan Hospitals
  • 1987-1988
    Chief Resident, Department of Internal Medicine, University of Michigan Hospitals
  • 1988-1991
    Hematology/Oncology Fellow, University of California, San Francisco
  • 1991-1992
    Molecular Medicine Fellow, University of California, San Francisco
  • 1989-1992
    Post-doctoral Research Fellow, University of California, San Francisco, Department of Microbiology & Immunology (Laboratory of Dr. Harold Varmus; Project: Biochemical characterization of retroviral integration)
  • 1992-2001
    Assistant Professor-in-residence, Department of Laboratory Medicine & Department of Medicine, UCSF
  • 1992-present
    Assistant Director, Blood Bank, Moffit-Long Hospitals, UCSF
  • 1994-present
    Medical Director, Adult Hematopoietic Progenitor Cell & Cellular Therapy Laboratory, Moffitt-Long Hospitals, UCSF
  • 2001-2007
    Associate Professor in Residence, Departments of Laboratory Medicine and Medicine (Div. of Hematology/Oncology), UCSF
  • 2007-present
    Professor in Residence, Departments of Laboratory Medicine and Medicine (Div. of Hematology/Oncology), UCSF

Honors & Awards

  • 1978-79
    James B. Angell Scholar, University of Michigan
  • 1979
    Phi Beta Kappa, University of Michigan
  • 1982-83
    Karin Grunebaum Cancer Research Foundation Fellowship, Harvard Medical School
  • 1984
    Cum Laude, Harvard Medical School
  • 1985
    Outstanding House Officer Award, Department of Internal Medicine, University of Michigan
  • 1991-92
    Burroughs Wellcome Research Fellowship
  • 1998
    Nomination for Small Group Teaching Award; UCSF Class of 2000
  • 2000
    Nomination for Small Group Teaching and Outstanding Lecture Award; UCSF Class of 2002
  • 2002
    Outstanding Lecture Award; UCSF Class of 2005
  • 2003
    Nominated for Kaiser Award for Excellence in Teaching
  • 2006
    Excellence in Teaching Award from the Haile T. Debas Academy of Medical Educator-UCSF

Selected Publications

  1. Kamata T, Dankort D, Kang J, Giblett S, Pritchard CA, McMahon M, Leavitt AD. Hematopoietic Expression of Oncogenic BRAF Promotes Aberrant Growth of Monocyte-Lineage Cells Resistant to PLX4720. Mol Cancer Res. 2013 Dec; 11(12):1530-41.
    View on PubMed
  2. Jacquot C, Moayeri M, Kim B, Shugarts S, Lynch KL, Leavitt AD. Prolonged ceftriaxone-induced immune thrombocytopenia due to impaired drug clearance: a case report. Transfusion. 2013 Nov; 53(11):2715-21.
    View on PubMed
  3. Choi YS, Patena W, Leavitt AD, McManus MT. Widespread RNA 3'-end oligouridylation in mammals. RNA. 2012 Mar; 18(3):394-401.
    View on PubMed
  4. Leavitt AD, Hamlett I. Homologous recombination in human embryonic stem cells: a tool for advancing cell therapy and understanding and treating human disease. Clin Transl Sci. 2011 Aug; 4(4):298-305.
    View on PubMed
  5. Bu W, Chen J, Morrison GD, Huang S, Creighton CJ, Huang J, Chamness GC, Hilsenbeck SG, Roop DR, Leavitt AD, Li Y. Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. Oncogene. 2011 Oct 27; 30(43):4399-409.
    View on PubMed
  6. Leavitt AD. A vote for scientists as politicians. Science. 2011 Feb 25; 331(6020):1010.
    View on PubMed
  7. Leavitt AD. Are there more tricks in the bag for treating thrombocytopenia? J Clin Invest. 2010 Nov; 120(11):3807-10.
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  8. King FW, Ritner C, Liszewski W, Kwan HC, Pedersen A, Leavitt AD, Bernstein HS. Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures. Stem Cells Dev. 2009 Dec; 18(10):1441-50.
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  9. Alian A, Griner SL, Chiang V, Tsiang M, Jones G, Birkus G, Geleziunas R, Leavitt AD, Stroud RM. Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs. Proc Natl Acad Sci U S A. 2009 May 19; 106(20):8192-7.
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  10. Nicholas CR, Gaur M, Wang S, Pera RA, Leavitt AD. A method for single-cell sorting and expansion of genetically modified human embryonic stem cells. Stem Cells Dev. 2007 Feb; 16(1):109-17.
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  11. Gaur M, Kamata T, Wang S, Moran B, Shattil SJ, Leavitt AD. Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function. J Thromb Haemost. 2006 Feb; 4(2):436-42.
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  12. Watson SP, Bahou WF, Fitzgerald D, Ouwehand W, Rao AK, Leavitt AD. Mapping the platelet proteome: a report of the ISTH Platelet Physiology Subcommittee. J Thromb Haemost. 2005 Sep; 3(9):2098-101.
    View on PubMed
  13. Kamata T, Kang J, Lee TH, Wojnowski L, Pritchard CA, Leavitt AD. A critical function for B-Raf at multiple stages of myelopoiesis. Blood. 2005 Aug 1; 106(3):833-40.
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  14. Kerrigan SW, Gaur M, Murphy RP, Shattil SJ, Leavitt AD. Caspase-12: a developmental link between G-protein-coupled receptors and integrin alphaIIbbeta3 activation. Blood. 2004 Sep 1; 104(5):1327-34.
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  15. Gaur M, Murphy GJ, Frampton J, Leavitt AD. Using retroviruses to express genes in primary megakaryocyte lineage cells. Methods Mol Biol. 2004; 273:381-96.
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  16. Kamata T, Pritchard CA, Leavitt AD. Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation. Blood. 2004 Apr 1; 103(7):2568-70.
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  17. Murphy GJ, Göttgens B, Vegiopoulos A, Sanchez MJ, Leavitt AD, Watson SP, Green AR, Frampton J. Manipulation of mouse hematopoietic progenitors by specific retroviral infection. J Biol Chem. 2003 Oct 31; 278(44):43556-63.
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  18. Eto K, Murphy R, Kerrigan SW, Bertoni A, Stuhlmann H, Nakano T, Leavitt AD, Shattil SJ. Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling. Proc Natl Acad Sci U S A. 2002 Oct 1; 99(20):12819-24.
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  19. Shattil SJ, Leavitt AD. All in the family: primary megakaryocytes for studies of platelet alphaIIbbeta3 signaling. Thromb Haemost. 2001 Jul; 86(1):259-65.
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  20. Gaur M, Murphy GJ, deSauvage FJ, Leavitt AD. Characterization of Mpl mutants using primary megakaryocyte-lineage cells from mpl(-/-) mice: a new system for Mpl structure-function studies. Blood. 2001 Mar 15; 97(6):1653-61.
    View on PubMed

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