University of California San Francisco
Helen Diller Family Comprehensive Cancer Center
Jeremy F. Reiter, MD, PhD

Jeremy F. Reiter, MD, PhD

Assistant Professor, Department of Biochemistry and Biophysics, UCSF

Cancer Center Program Memberships

Pediatric Malignancies


Yale College, New Haven, CT, BA, 1989-1993, Molecular Biochemistry and Biophysics
University of California, San Francisco, PhD, 1995-1999, Developmental Biology
University of California, San Francisco, MD, 1993-1995, 1999-2001, Medicine
University of California, Berkeley, Postdoctoral, 2001-2003, Developmental Biology

Professional Experience

  • 2001-2003
    Postdoctoral Fellow with Dr. William C. Skarnes, University of California, Berkeley
  • 2003-2006
    UCSF Fellow, Developmental and Stem Cell Biology Program, University of California, San Francisco
  • 2006-present
    Assistant Professor, Department of Biochemistry and Biophysics, and Cardiovascular Research Institute, University of California, San Francisco

Honors & Awards

  • 1993
    Regents Scholar, University of California
  • 1999
    Achievement Award for College Scientists
  • 2001
    Alpha Omega Alpha Honors Medical Society
  • 1994-2001
    National Institutes of Health Medical Scientist Training Program
  • 2004-2006
    March of Dimes Basil O'Connor Research Award
  • 2005-2010
    Burroughs Wellcome Fund Career Award in the Biomedical Sciences
  • 2006-present
    Developmental Dynamic Editorial Board
  • 2007
    Best Faculty Talk, West Coast Society of Developmental Biology Conference
  • 2007-2012
    Packard Fellow for Science and Engineering
  • 2009
    Elected to the American Society for Clinical Investigation (ASCI)
  • 2009
    Presidential Early Career Award for Scientists and Engineers (PECASE)

Selected Publications

  • Reiter, J.F., Alexander, J., Yelon, D., Patient, R., Holder, N. and Stainier, D.Y. (1999). Gata5 is required for the development of the heart and endoderm in zebrafish. Genes and Development 13:2983-2995.
  • Kikuchi, Y., Trinh, L., Reiter, J.F., Alexander, J., Yelon, D. and Stainier, D.Y. (2000) The zebrafish bonnie and clyde gene encodes a Mix family homeodomain protein that regulates generation of the endodermal precursors. Genes and Development 14:1279-1289.
  • Reiter, J.F., Kikuchi, Y. and Stainier, D.Y. (2001). Multiple roles for Gata5 in early zebrafish endoderm formation. Development 128:125-135.
  • Reiter, J.F., Verkade, H. and Stainier, D.Y. (2001). Bmp2b and Oep promote myocardial differentiation through their regulation of gata5. Developmental Biology 234:330-338.
  • Kikuchi, Y., Verkade, H., Reiter, J. F., Kim, C.-H., Chitnis, A.B., Kuroiwa, A. and Stainier. D.Y. (2004). Notch signaling can regulate endoderm formation in zebrafish. Developmental Dynamics 229:756-762.
  • May, S.R., Ashique, A.M., Karlen, M., Wang, B., Shen, Y., Zarbalis, K., Reiter, J.F., Ericson, J. and Peterson, A.S. (2005). Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev Biology 287:378-89.
  • Corbit, K.C., Aanstad, P., Norman, A.R., Singla, V., Stainier, D.Y. and Reiter, J.F. (2005). Vertebrate Smoothened functions at the primary cilium. Nature 437:1018-1021.
  • Reiter, J.F. and Skarnes, W.C. (2006). Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. Genes and Development 20:22-7.
  • Singla, V. and Reiter, J.F. (2006). The primary cilium as the cell's antenna: Signaling at a sensory organelle. Science 313:629-633.
  • Reiter, J.F.. and K. Mostov. (2006). Vesicle transport, cilium formation, and membrane specialization: the origins of a sensory organelle. Proc Natl Acad Sci USA 103:18383-18384.
  • Corbit, K.C., Shyer, A. E., Dowdle, W.E., Gaulden, J., Singla, V., Chen, M.H., Chaung, P.T. and Reiter, J.F. (2007). Kif3a constrains beta-catenin-dependent Wnt signaling through dual ciliary and non-ciliary mechanisms. Nature Cell Biology 10:70-84.
  • Santos, N. and Reiter, J.F. (2008). Building it up and taking it down: the regulation of vertebrate ciliogenesis. Dev Dyn 237:1972-1981.
  • Reiter, J.F. (2008). A cilium is not a cilium is not a cilium: signaling contributes to ciliary morphological diversity. Dev Cell 14:635-636.
  • Gaulden, J. and Reiter, J.F. (2008). Neur-ons and neur-offs: regulators of neural induction in vertebrate embryos and embryonic stem cells. Hum Mol Genet 17: 60-66.
  • Wong, S.Y. and Reiter, J.F. (2008). The primary cilium at the crossroads of mammalian Hedgehog signaling. Curr Top Dev Biol. 85:225-260.
  • Aanstad, P., Santos, N., Corbit, K.C., Scherz, P.J., Trinh, L.A., Salvenmoser, W., Huisken, J., Reiter, J.F., and Stainier, D. Y. (2009). The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling. Curr Biol. 19:1034-9.
  • Wong, S.Y., Seol, A., So, P.-L., Ermilov, A.N., Bichakjian, C.K., Epstein, E.H. Jr., Dlugosz, A.A., and Reiter, J.F. (2009). Primary Cilia Can Both Mediate and Suppress Hedgehog Pathway-Dependent Tumorigenesis. Nature Medicine 100:181-90.
  • Singla, V., Hunkapiller, J., Santos, N., Seol, A., Norman, A., Skarnes, W. C., and J. F. Reiter. (2010) Floxin, a resource for genetically engineering mouse ESCs. Nature Methods. 7: 50-2.
  • Walker, E., Chang, E. Y., Hunkapiller, J., Cagney, G., Garcha, K., Tochia, J., Krogan, N. J., Reiter, J. F., and W. L. Stanford. (2010) Polycomb-like 2, in association with PRC2, regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. Cell Stem Cell. 6: 153-66.
  • Singla, V., Romaguera-Ros, M., Garcia-Verdugo, J. and J. F. Reiter. (2010) Ofd1, a human disease gene, regulates the length and distal structure of centrioles. Developmental Cell. 18:410-24.