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James L. Rubenstein, MD, PhD

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
rubenstein_james

Professor in Residence, Department of Medicine, UCSF

Phone: (415) 353-2421 (appts)
Box 1270, UCSF
San Francisco, CA 94143-1270

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Additional Websites


Education

Stanford University, B.S., June 1985, Biological Sciences
The Rockefeller University, Ph.D., June 1991, Molecular and Cellular Neuroscience (Medical Scientist Training Program)
Cornell University Medical College, M.D., May 1992, Medicine
Stanford University Medical Center, Stanford, CA, Internship/Residency, 1992-1995, Internal Medicine
University of California, San Francisco, San Francisco, CA, Fellowship, 1992-1998, Hematology/Oncology and Neuro-Oncology


Professional Experience

  • 1998-2006
    Assistant Adjunct Professor of Medicine, Attending Physician in Hematology/Oncology, University of California, San Francisco
  • 2006-2009
    Assistant Professor of Medicine in Residence, University of California, San Francisco
  • 2009-2013
    Associate Professor of Medicine in Residence, University of California, San Francisco
  • 2013-present
    Professor in Residence, Department of Medicine, University of California, San Francisco

Honors & Awards

  • 1985
    Phi Beta Kappa
  • 1985
    Departmental Honors in Biological Sciences
  • 1985
    Honors in Humanities
  • 1995
    Housestaff Research Award
  • 1998
    Young Investigator Award -American Society of Clinical Oncology
  • 1999
    American Brain Tumor Association Fellowship
  • 2000
    UCSF/Mt Zion Clinical Investigator Research Program
  • 2000
    California Cancer Research Program Clinical Scientist Development Award
  • 2001
    UCSF/Mt Zion Clinical Investigator Research Program
  • 2001
    Career Development Award-American Society of Clinical Oncology
  • 2001
    Accelerate Brain Cancer Cure Foundation Award
  • 2002
    UCSF Research Evaluation and Allocation Committee Award
  • 2003
    UC Discovery Grant
  • 2003
    Tobacco-Related Disease Research Program IDEA Award
  • 2004
    National Cancer Institute Research Career Award
  • 2004
    American Cancer Society Award
  • 2005
    UCSF Brain Tumor SPORE Development Award
  • 2006
    G&P Foundation Award
  • 2008
    UCSF Clinical and Translational Sciences Grant
  • 2009
    Scholar in Clinical Research Award, Leukemia & Lymphoma Society
  • 2011
    Sandler Award Program in Breakthrough Biomedical Research
  • 2013
    Translational Research Program Award, Leukemia & Lymphoma Society
    Invited Lectures

Selected Publications

  1. Wang CC, Carnevale J, Rubenstein JL. Progress in central nervous system lymphomas. Br J Haematol. 2014 Aug; 166(3):311-25.
    View on PubMed
  2. Rubenstein JL, Cheson BD, Jung SH, Kaplan LD. Reply to m.C. Chamberlain. J Clin Oncol. 2014 Mar 10; 32(8):858-9.
    View on PubMed
  3. Kadoch C, Li J, Wong VS, Chen L, Cha S, Munster P, Lowell CA, Shuman MA, Rubenstein JL. Complement activation and intraventricular rituximab distribution in recurrent central nervous system lymphoma. Clin Cancer Res. 2014 Feb 15; 20(4):1029-41.
    View on PubMed
  4. Rubenstein JL, Gupta NK, Mannis GN, Lamarre AK, Treseler P. How I treat CNS lymphomas. Blood. 2013 Oct 3; 122(14):2318-30.
    View on PubMed
  5. Rubenstein JL, Wong VS, Kadoch C, Gao HX, Barajas R, Chen L, Josephson SA, Scott B, Douglas V, Maiti M, Kaplan LD, Treseler PA, Cha S, Hwang JH, Cinque P, Cyster JG, Lowell C. CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma. Blood. 2013 Jun 6; 121(23):4740-8.
    View on PubMed
  6. Rubenstein JL, Hsi ED, Johnson JL, Jung SH, Nakashima MO, Grant B, Cheson BD, Kaplan LD. Intensive chemotherapy and immunotherapy in patients with newly diagnosed primary CNS lymphoma: CALGB 50202 (Alliance 50202). J Clin Oncol. 2013 Sep 1; 31(25):3061-8.
    View on PubMed
  7. Scott BJ, Douglas VC, Tihan T, Rubenstein JL, Josephson SA. A systematic approach to the diagnosis of suspected central nervous system lymphoma. JAMA Neurol. 2013 Mar 1; 70(3):311-9.
    View on PubMed
  8. Rubenstein JL, Li J, Chen L, Advani R, Drappatz J, Gerstner E, Batchelor T, Krouwer H, Hwang J, Auerback G, Kadoch C, Lowell C, Munster P, Cha S, Shuman MA, Damon LE. Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma. Blood. 2013 Jan 31; 121(5):745-51.
    View on PubMed
  9. Wieduwilt MJ, Valles F, Issa S, Behler CM, Hwang J, McDermott M, Treseler P, O'Brien J, Shuman MA, Cha S, Damon LE, Rubenstein JL. Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI. Clin Cancer Res. 2012 Feb 15; 18(4):1146-55.
    View on PubMed
  10. Chan CC, Rubenstein JL, Coupland SE, Davis JL, Harbour JW, Johnston PB, Cassoux N, Touitou V, Smith JR, Batchelor TT, Pulido JS. Primary vitreoretinal lymphoma: a report from an International Primary Central Nervous System Lymphoma Collaborative Group symposium. Oncologist. 2011; 16(11):1589-99.
    View on PubMed
  11. Rubenstein JL, Treseler PA, Stewart PJ. Regression of refractory intraocular large B-cell lymphoma with lenalidomide monotherapy. J Clin Oncol. 2011 Jul 10; 29(20):e595-7.
    View on PubMed
  12. Algazi AP, Kadoch C, Rubenstein JL. Biology and treatment of primary central nervous system lymphoma. Neurotherapeutics. 2009 Jul; 6(3):587-97.
    View on PubMed
  13. Kadoch C, Dinca EB, Voicu R, Chen L, Nguyen D, Parikh S, Karrim J, Shuman MA, Lowell CA, Treseler PA, James CD, Rubenstein JL. Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model. Clin Cancer Res. 2009 Mar 15; 15(6):1989-97.
    View on PubMed
  14. Mrugala MM, Rubenstein JL, Ponzoni M, Batchelor TT. Insights into the biology of primary central nervous system lymphoma. Curr Oncol Rep. 2009 Jan; 11(1):73-80.
    View on PubMed
  15. Rubenstein JL, Shen A, Batchelor TT, Kadoch C, Treseler P, Shuman MA. Differential gene expression in central nervous system lymphoma. Blood. 2009 Jan 1; 113(1):266-7; author reply 267-8.
    View on PubMed
  16. Yang I, Delpolyi A, Sughrue ME, Rubenstein J, Bollen AW, Parsa AT. Sarcoidosis of the pineal gland: an unusual presentation of neurosarcoidosis. J Neurooncol. 2009 Jan; 91(1):113-6.
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  17. Rubenstein J, Ferreri AJ, Pittaluga S. Primary lymphoma of the central nervous system: epidemiology, pathology and current approaches to diagnosis, prognosis and treatment. Leuk Lymphoma. 2008; 49 Suppl 1:43-51.
    View on PubMed
  18. Roy S, Josephson SA, Fridlyand J, Karch J, Kadoch C, Karrim J, Damon L, Treseler P, Kunwar S, Shuman MA, Jones T, Becker CH, Schulman H, Rubenstein JL. Protein biomarker identification in the CSF of patients with CNS lymphoma. J Clin Oncol. 2008 Jan 1; 26(1):96-105.
    View on PubMed
  19. Rubenstein JL, Fridlyand J, Abrey L, Shen A, Karch J, Wang E, Issa S, Damon L, Prados M, McDermott M, O'Brien J, Haqq C, Shuman M. Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma. J Clin Oncol. 2007 Apr 10; 25(11):1350-6.
    View on PubMed
  20. Kadoch C, Treseler P, Rubenstein JL. Molecular pathogenesis of primary central nervous system lymphoma. Neurosurg Focus. 2006; 21(5):E1.
    View on PubMed

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