Associate Professor in Residence, Department of Medicine, UCSF
Additional Websites
Education
Stanford University, B.S., June 1985, Biological Sciences
The Rockefeller University, Ph.D., June 1991, Molecular and Cellular Neuroscience (Medical Scientist Training Program)
Cornell University Medical College, M.D., May 1992, Medicine
Stanford University Medical Center, Stanford, CA, Internship/Residency, 1992-1995, Internal Medicine
University of California, San Francisco, San Francisco, CA, Fellowship, 1992-1998, Hematology/Oncology and Neuro-Oncology
Professional Experience
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1998-2006
Assistant Adjunct Professor of Medicine, Attending Physician in Hematology/Oncology, University of California, San Francisco
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2006-2009
Assistant Professor of Medicine in Residence, University of California, San Francisco
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2009-present
Associate Professor of Medicine in Residence, University of California, San Francisco
Honors & Awards
- 1985
Phi Beta Kappa - 1985
Departmental Honors in Biological Sciences - 1985
Honors in Humanities - 1995
Housestaff Research Award - 1998
Young Investigator Award -American Society of Clinical Oncology - 1999
American Brain Tumor Association Fellowship - 2000
UCSF/Mt Zion Clinical Investigator Research Program - 2000
California Cancer Research Program Clinical Scientist Development Award - 2001
UCSF/Mt Zion Clinical Investigator Research Program - 2001
Career Development Award-American Society of Clinical Oncology - 2001
Accelerate Brain Cancer Cure Foundation Award - 2002
UCSF Research Evaluation and Allocation Committee Award - 2003
UC Discovery Grant - 2003
Tobacco-Related Disease Research Program IDEA Award - 2004
National Cancer Institute Research Career Award - 2004
American Cancer Society Award - 2005
UCSF Brain Tumor SPORE Development Award - 2006
G&P Foundation Award - 2008
UCSF Clinical and Translational Sciences Grant - 2009
Scholar in Clinical Research Award, Leukemia & Lymphoma Society - 2009
Cancer and Leukemia Group B Clinical Scholars Award
Selected Publications
- Scott BJ, Douglas VC, Tihan T, Rubenstein JL, Josephson SA. A systematic approach to the diagnosis of suspected central nervous system lymphoma. JAMA Neurol. 2013 Mar 1; 70(3):311-9.
View on PubMed - Rubenstein JL, Li J, Chen L, Advani R, Drappatz J, Gerstner E, Batchelor T, Krouwer H, Hwang J, Auerback G, Kadoch C, Lowell C, Munster P, Cha S, Shuman MA, Damon LE. Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma. Blood. 2013 Jan 31; 121(5):745-51.
View on PubMed - Wieduwilt MJ, Valles F, Issa S, Behler CM, Hwang J, McDermott M, Treseler P, O'Brien J, Shuman MA, Cha S, Damon LE, Rubenstein JL. Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI. Clin Cancer Res. 2012 Feb 15; 18(4):1146-55.
View on PubMed - Chan CC, Rubenstein JL, Coupland SE, Davis JL, Harbour JW, Johnston PB, Cassoux N, Touitou V, Smith JR, Batchelor TT, Pulido JS. Primary vitreoretinal lymphoma: a report from an International Primary Central Nervous System Lymphoma Collaborative Group symposium. Oncologist. 2011; 16(11):1589-99.
View on PubMed - Rubenstein JL, Treseler PA, Stewart PJ. Regression of refractory intraocular large B-cell lymphoma with lenalidomide monotherapy. J Clin Oncol. 2011 Jul 10; 29(20):e595-7.
View on PubMed - Algazi AP, Kadoch C, Rubenstein JL. Biology and treatment of primary central nervous system lymphoma. Neurotherapeutics. 2009 Jul; 6(3):587-97.
View on PubMed - Kadoch C, Dinca EB, Voicu R, Chen L, Nguyen D, Parikh S, Karrim J, Shuman MA, Lowell CA, Treseler PA, James CD, Rubenstein JL. Pathologic correlates of primary central nervous system lymphoma defined in an orthotopic xenograft model. Clin Cancer Res. 2009 Mar 15; 15(6):1989-97.
View on PubMed - Mrugala MM, Rubenstein JL, Ponzoni M, Batchelor TT. Insights into the biology of primary central nervous system lymphoma. Curr Oncol Rep. 2009 Jan; 11(1):73-80.
View on PubMed - Rubenstein JL, Shen A, Batchelor TT, Kadoch C, Treseler P, Shuman MA. Differential gene expression in central nervous system lymphoma. Blood. 2009 Jan 1; 113(1):266-7; author reply 267-8.
View on PubMed - Yang I, Delpolyi A, Sughrue ME, Rubenstein J, Bollen AW, Parsa AT. Sarcoidosis of the pineal gland: an unusual presentation of neurosarcoidosis. J Neurooncol. 2009 Jan; 91(1):113-6.
View on PubMed - Rubenstein J, Ferreri AJ, Pittaluga S. Primary lymphoma of the central nervous system: epidemiology, pathology and current approaches to diagnosis, prognosis and treatment. Leuk Lymphoma. 2008; 49 Suppl 1:43-51.
View on PubMed - Roy S, Josephson SA, Fridlyand J, Karch J, Kadoch C, Karrim J, Damon L, Treseler P, Kunwar S, Shuman MA, Jones T, Becker CH, Schulman H, Rubenstein JL. Protein biomarker identification in the CSF of patients with CNS lymphoma. J Clin Oncol. 2008 Jan 1; 26(1):96-105.
View on PubMed - Rubenstein JL, Fridlyand J, Abrey L, Shen A, Karch J, Wang E, Issa S, Damon L, Prados M, McDermott M, O'Brien J, Haqq C, Shuman M. Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma. J Clin Oncol. 2007 Apr 10; 25(11):1350-6.
View on PubMed - Kadoch C, Treseler P, Rubenstein JL. Molecular pathogenesis of primary central nervous system lymphoma. Neurosurg Focus. 2006; 21(5):E1.
View on PubMed - Rubenstein JL, Fridlyand J, Shen A, Aldape K, Ginzinger D, Batchelor T, Treseler P, Berger M, McDermott M, Prados M, Karch J, Okada C, Hyun W, Parikh S, Haqq C, Shuman M. Gene expression and angiotropism in primary CNS lymphoma. Blood. 2006 May 1; 107(9):3716-23.
View on PubMed - Orr JW, Dosoretz DD, Mahoney D, Roland PY, Kelly FJ, Blitzer P, Nakfoor B, Katin M, Rubenstein J, Boothby RR. Surgically (laparotomy/laparoscopy) guided placement of high dose rate interstitial irradiation catheters (LG-HDRT): technique and outcome. Gynecol Oncol. 2006 Jan; 100(1):145-8.
View on PubMed - Rubenstein JL, Treseler P, O'Brien JM. Pathology and genetics of primary central nervous system and intraocular lymphoma. Hematol Oncol Clin North Am. 2005 Aug; 19(4):705-17, vii.
View on PubMed - Shenkier TN, Blay JY, O'Neill BP, Poortmans P, Thiel E, Jahnke K, Abrey LE, Neuwelt E, Tsang R, Batchelor T, Harris N, Ferreri AJ, Ponzoni M, O'Brien P, Rubenstein J, Connors JM. Primary CNS lymphoma of T-cell origin: a descriptive analysis from the international primary CNS lymphoma collaborative group. J Clin Oncol. 2005 Apr 1; 23(10):2233-9.
View on PubMed - Rubenstein JL, Combs D, Rosenberg J, Levy A, McDermott M, Damon L, Ignoffo R, Aldape K, Shen A, Lee D, Grillo-Lopez A, Shuman MA. Rituximab therapy for CNS lymphomas: targeting the leptomeningeal compartment. Blood. 2003 Jan 15; 101(2):466-8.
View on PubMed - Rubenstein J, Fischbein N, Aldape K, Burton E, Shuman M. Hemorrhage and VEGF expression in a case of primary CNS lymphoma. J Neurooncol. 2002 May; 58(1):53-6.
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