Rebecca Smith-Bindman, MD

Rebecca Smith-Bindman, MD

Professor in Residence, Departments of Radiology, Epidemiology/Biostatistics, and Obstetrics, Gynecology, and Reproductive Medicine, UCSF

Phone: (415) 353-2573 (appts)
Box 1667, UCSF
San Francisco, CA 94143-1667

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Cancer Center Membership

Program Member » Breast Oncology

Research Summary

Rebecca Smith-Bindman, MD, is a Professor in Residence of Radiology, Epidemiology and Biostatistics, Obstetrics, Gynecology and Reproductive Medicine. Dr. Smith–Bindman directs the Radiology Outcomes Research Laboratory. She provides her expertise in the diagnosis of fetal anomalies, the evaluation of patients with symptoms of vaginal bleeding, and helps to understand efficient ways to evaluate a range of symptoms to minimize unnecessary and excessive testing while maximizing accurate diagnoses. Dr. Smith-Bindman received her medical degree from the University of California, San Francisco in 1991, and completed her residency in Radiology at UCSF in 1996, followed by a fellowship in Epidemiology and Biostatistics at UCSF in 1998.

Dr. Smith-Bindman’s research continues to concentrate on understanding the impact of diagnostic testing on important patient outcomes and understanding the difference in access to different tests and variance in accuracy of these tests. Present research projects are assessing the risk of cancer associated with incidental findings identified on ultrasound and CT imaging, and assessing patterns of radiation from diagnostic imaging.

Dr. Smith-Bindman has 68 peer-reviewed articles. In many of her studies, she was responsible for the design, data collection, analysis, manuscript preparation, and dissemination of the results. A few of her significant articles have been covered by extensive media coverage such as the New York Times and the Wall Street Journal.




Diagnosis of fetal anomalies, the evaluation of patients with symptoms of vaginal bleeding, and helping to understand efficient ways to evaluate a range of symptoms to minimize unnecessary and excessive testing while maximizing accurate diagnoses

Professional Interests:

Comparative effectiveness and diagnostic imaging, health services research, outcomes research, disparities research, women's imaging, mammography, evidenced based radiology, screening tests, radiation associated with medical imaging, management of incidental findings on diagnostic testing

Education and Training:

• Medical School: University of California, San Francisco

• Internship: University of California, San Francisco - Pathology

• Residency: University of California, San Francisco - Radiology

• Fellowship: University of California, San Francisco - Epidemiology and Biostatistics

• California Medical License

• California X-ray Supervisor and Operator License

• Board Certification, American Board of Radiology


Princeton University, Princeton, NJ, B.S.E., 1985, Architecture/Engineering
Columbia University, New York, NY, 7/85-6/86, Pre-Medical Program
University of California, San Francisco, CA, M.D., 1991, Medicine

Professional Experience

  • 1986-1987
    Research Assistant, Radiology and General Internal Medicine, UCSF
  • 1991-1992
    Intern, Department of Pathology, UCSF
  • 1992-1996
    Resident, Department of Radiology, UCSF
  • 1996-1997
    Clinical Instructor, Ultrasound, Department of Radiology, UCSF
  • 1996-1998
    Fellow, Women's Health, Epidemiology, Biostatistics, and Medicine, UCSF
  • 1998-2000
    Asst. Adjunct Professor of Radiology, Epidemiology & Biostatistics, UCSF
  • 1998-2000
    Asst. Adjunct Professor of Epidemiology & Biostatistics, UCSF
  • 1999-2000
    Visiting Research Fellow, Dept. of Environmental and Preventive Medicine, Wolfson Institute, St. Bartholowmew's and The Royal London School of Medicine
  • 2000-current
    Assistant Professor in Residence, Radiology, Epidemiology and Biostatistics, UCSF
  • 2000-current
    Director, Radiology Outcomes Research Lab
  • 2003-current
    Associate Professor in Residence, Radiology, Epidemiology and Biostatistics, Obstetrics, Gynecology, and Reproductive Medicine, UCSF

Honors & Awards

  • 1985
    Cum laude, Princeton University
  • 1985
    Senior Thesis Prize, Princeton University
  • 1988
    Student Summer Research Fellowship, Institute for Health Policy, UCSF
  • 1999, 2000
    Radiologic Society of North America Nycomed Amersham Fellow

Selected Publications

  1. Smith-Bindman R, Bindman AB. Imaging More Wisely-Already At Work-Reply. JAMA Intern Med. 2016 Jun 1; 176(6):870-1.
    View on PubMed
  2. Melnikow J, Xing G, Cox G, Leigh P, Mills L, Miglioretti DL, Moghadassi M, Smith-Bindman R. Cost Analysis of the STONE Randomized Trial: Can Health Care Costs be Reduced One Test at a Time? Med Care. 2016 Apr; 54(4):337-42.
    View on PubMed
  3. Harrison JD, Balonov M, Martin CJ, Ortiz Lopez P, Menzel HG, Simmonds JR, Smith-Bindman R, Wakeford R. Use of effective dose. Ann ICRP. 2016 Jun; 45(1 Suppl):215-24.
    View on PubMed
  4. Fenton JJ, Onega T, Zhu W, Balch S, Smith-Bindman R, Henderson L, Sprague BL, Kerlikowske K, Hubbard RA. Validation of a Medicare Claims-based Algorithm for Identifying Breast Cancers Detected at Screening Mammography. Med Care. 2016 Mar; 54(3):e15-22.
    View on PubMed
  5. Smith-Bindman R, Bindman AB. Imaging More Wisely. JAMA Intern Med. 2016 Feb 1; 176(2):168-70.
    View on PubMed
  6. Smith-Bindman R, Kwan ML, Miglioretti DL. Who Gets to Decide? Radiology. 2016 Feb; 278(2):635-7.
    View on PubMed
  7. Morgan TA, Smith-Bindman R, Harbell J, Kornak J, Stock PG, Feldstein VA. US Findings in Patients at Risk for Pancreas Transplant Failure. Radiology. 2016 Jul; 280(1):281-9.
    View on PubMed
  8. Wang RC, Bent S, Weber E, Neilson J, Smith-Bindman R, Fahimi J. The Impact of Clinical Decision Rules on Computed Tomography Use and Yield for Pulmonary Embolism: A Systematic Review and Meta-analysis. Ann Emerg Med. 2016 Jun; 67(6):693-701.e3.
    View on PubMed
  9. Smith-Bindman R, Miglioretti D. Cell-free DNA Analysis for Noninvasive Examination of Trisomy. N Engl J Med. 2015 Dec 24; 373(26):2581.
    View on PubMed
  10. Solberg LI, Asche SE, Butler J, Carrell D, Norton CK, Jarvik JG, Smith-Bindman R, Tillema JO, Whitebird RR, Ziegenfuss JY. The Effect of Achieving Patient-Reported Outcome Measures on Satisfaction. J Am Board Fam Med. 2015 Nov-Dec; 28(6):785-92.
    View on PubMed
  11. Wang RC, Rodriguez RM, Moghadassi M, Noble V, Bailitz J, Mallin M, Corbo J, Kang TL, Chu P, Shiboski S, Smith-Bindman R. External Validation of the STONE Score, a Clinical Prediction Rule for Ureteral Stone: An Observational Multi-institutional Study. Ann Emerg Med. 2016 Apr; 67(4):423-432.e2.
    View on PubMed
  12. Bahadori A, Miglioretti D, Kruger R, Flynn M, Weinmann S, Smith-Bindman R, Lee C. Calculation of Organ Doses for a Large Number of Patients Undergoing CT Examinations. AJR Am J Roentgenol. 2015 Oct; 205(4):827-33.
    View on PubMed
  13. Onega T, Goldman LE, Walker RL, Miglioretti DL, Buist DS, Taplin S, Geller BM, Hill DA, Smith-Bindman R. Facility Mammography Volume in Relation to Breast Cancer Screening Outcomes. J Med Screen. 2016 Mar; 23(1):31-7.
    View on PubMed
  14. Smith-Bindman R, Moghadassi M, Griffey RT, Camargo CA, Bailitz J, Beland M, Miglioretti DL. Computed Tomography Radiation Dose in Patients With Suspected Urolithiasis. JAMA Intern Med. 2015 Aug; 175(8):1413-6.
    View on PubMed
  15. Smith-Bindman R, Moghadassi M, Wilson N, Nelson TR, Boone JM, Cagnon CH, Gould R, Hall DJ, Krishnam M, Lamba R, McNitt-Gray M, Seibert A, Miglioretti DL. Radiation Doses in Consecutive CT Examinations from Five University of California Medical Centers. Radiology. 2015 Oct; 277(1):134-41.
    View on PubMed
  16. Mongan J, Kline J, Smith-Bindman R. Age and sex-dependent trends in pulmonary embolism testing and derivation of a clinical decision rule for young patients. Emerg Med J. 2015 Nov; 32(11):840-5.
    View on PubMed
  17. Smith-Bindman R. Ultrasonography vs. CT for suspected nephrolithiasis. N Engl J Med. 2014 Dec 25; 371(26):2531.
    View on PubMed
  18. Hubbard RA, Benjamin-Johnson R, Onega T, Smith-Bindman R, Zhu W, Fenton JJ. Classification accuracy of claims-based methods for identifying providers failing to meet performance targets. Stat Med. 2015 Jan 15; 34(1):93-105.
    View on PubMed
  19. Smith-Bindman R, Aubin C, Bailitz J, Bengiamin RN, Camargo CA, Corbo J, Dean AJ, Goldstein RB, Griffey RT, Jay GD, Kang TL, Kriesel DR, Ma OJ, Mallin M, Manson W, Melnikow J, Miglioretti DL, Miller SK, Mills LD, Miner JR, Moghadassi M, Noble VE, Press GM, Stoller ML, Valencia VE, Wang J, Wang RC, Cummings SR. Ultrasonography versus computed tomography for suspected nephrolithiasis. N Engl J Med. 2014 Sep 18; 371(12):1100-10.
    View on PubMed
  20. Fenton JJ, Zhu W, Balch S, Smith-Bindman R, Fishman P, Hubbard RA. Distinguishing screening from diagnostic mammograms using Medicare claims data. Med Care. 2014 Jul; 52(7):e44-51.
    View on PubMed

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